GNG4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	GNG4
Entrez Gene ID	2786
Full Name	G protein subunit gamma 4
General protein information	Preferred Names G protein subunit gamma 4 Names guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 guanine nucleotide binding protein (G protein), gamma 4 guanine nucleotide binding protein 4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q42.3
Disorder MIM:	604388

mRNA and Protein(s)

mRNA	Protein	Name
NM_001098721.1	NP_001092191.1	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 precursor
NM_001098722.2	NP_001092192.1	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 precursor
NM_004485.3	NP_004476.1	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 precursor
NM_001098722.1	NP_001092192.1	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 precursor
NM_004485.4	NP_004476.1	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 precursor
XM_006711761.2	XP_006711824.1	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 isoform X1
XM_011544167.2	XP_011542469.1	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	GNG4	XP_849303.2
Xenopus tropicalis (tropical clawed frog)	gng4	NP_001165066.1
Mus musculus (house mouse)	Gng4	NP_034447.1
Homo sapiens (human)	GNG4	NP_001092191.1
Pan troglodytes (chimpanzee)	GNG4	XP_001155515.1
Bos taurus (cattle)	GNG4	NP_001096794.1
Rattus norvegicus (Norway rat)	Gng4	XP_003751785.1
Gallus gallus (chicken)	GNG4	XP_004935529.1
	LOC718223	XP_001110597.2

Gene Ontology
Bibliography

Related articles in PubMed

Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for GNG4 and KCNQ2 Genes.
Bonham LW, Evans DS, Liu Y, Cummings SR, Yaffe K, Yokoyama JS
American journal of Alzheimer's disease and other dementias1533317517739384(2018 Jan)

TREK-1 and Best1 channels mediate fast and slow glutamate release in astrocytes upon GPCR activation.
Woo DH, Han KS, Shim JW, Yoon BE, Kim E, Bae JY, Oh SJ, Hwang EM, Marmorstein AD, Bae YC, Park JY, Lee CJ
Cell151(1)25-40(2012 Sep)

Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study.
Lunetta KL, D'Agostino RB Sr, Karasik D, Benjamin EJ, Guo CY, Govindaraju R, Kiel DP, Kelly-Hayes M, Massaro JM, Pencina MJ, Seshadri S, Murabito JM
BMC medical genetics8 Suppl 1S13(2007 Sep)

Evidence for association of GABA(B) receptors with Kir3 channels and regulators of G protein signalling (RGS4) proteins.
Fowler CE, Aryal P, Suen KF, Slesinger PA
The Journal of physiology580(Pt 1)51-65(2007 Apr)

Identification of novel VHL target genes and relationship to hypoxic response pathways.
Maina EN, Morris MR, Zatyka M, Raval RR, Banks RE, Richards FM, Johnson CM, Maher ER
Oncogene24(28)4549-58(2005 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following GNG4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GNG4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu12701	NM_001098722.2 Latest version!	Homo sapiens G protein subunit gamma 4 (GNG4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu12701	NM_004485.4 Latest version!	Homo sapiens G protein subunit gamma 4 (GNG4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu12701	NM_001098721.1 Latest version!	Homo sapiens G protein subunit gamma 4 (GNG4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu12701	XM_006711761.2 Latest version!	Homo sapiens G protein subunit gamma 4 (GNG4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu12701	XM_011544167.2 Latest version!	Homo sapiens G protein subunit gamma 4 (GNG4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu12701	NM_001098722.1	Homo sapiens G protein subunit gamma 4 (GNG4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu12701	NM_004485.3	Homo sapiens G protein subunit gamma 4 (GNG4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GNG4 ( NM_001098722.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001092192.1 Homo sapiens G protein subunit gamma 4 (GNG4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu12701
Clone ID Related Accession (Same CDS sequence)	NM_001098721.1 , NM_001098722.2 , NM_004485.3 , NM_001098722.1 , NM_004485.4 , XM_006711761.2 , XM_011544167.2
Accession Version	NM_001098722.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 228bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-12
Organism	Homo sapiens(human)
Product	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CX784976.1, AK311781.1, FO393422.1 and AK074383.1. On Nov 22, 2018 this sequence version replaced NM_001098722.1. Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, and 3 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.297756.1, SRR1803613.82635.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000391854.7/ ENSP00000375727.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAAGAGG GCATGTCTAA TAACAGCACC ACTAGCATCT CCCAAGCCAG GAAAGCTGTG 
GAGCAGCTAA AGATGGAAGC CTGTATGGAC AGGGTCAAGG TCTCCCAGGC AGCTGCGGAC 
CTCCTGGCCT ACTGTGAAGC TCACGTGCGG GAAGATCCTC TCATCATTCC AGTGCCTGCA 
TCAGAAAACC CCTTTCGCGA GAAGAAGTTC TTTTGTACCA TTCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001092192.1
CDS	246..473
Translation	MKEGMSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFREKKFFCTIL

Target ORF information:

RefSeq Version	NM_001098722.2
Organism	Homo sapiens(human)
Definition	Homo sapiens G protein subunit gamma 4 (GNG4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001098722.2

ORF Insert Sequence:

ATGAAAGAGG GCATGTCTAA TAACAGCACC ACTAGCATCT CCCAAGCCAG GAAAGCTGTG 
GAGCAGCTAA AGATGGAAGC CTGTATGGAC AGGGTCAAGG TCTCCCAGGC AGCTGCGGAC 
CTCCTGGCCT ACTGTGAAGC TCACGTGCGG GAAGATCCTC TCATCATTCC AGTGCCTGCA 
TCAGAAAACC CCTTTCGCGA GAAGAAGTTC TTTTGTACCA TTCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GNG4 ( NM_001098721.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001092191.1 Homo sapiens G protein subunit gamma 4 (GNG4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu12701
Clone ID Related Accession (Same CDS sequence)	NM_001098721.1 , NM_001098722.2 , NM_004485.3 , NM_001098722.1 , NM_004485.4 , XM_006711761.2 , XM_011544167.2
Accession Version	NM_001098721.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 228bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-12
Organism	Homo sapiens(human)
Product	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC022485.1, DA230013.1, AK311781.1, FO393422.1 and AK074383.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.252565.1, SRR1660807.168242.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAAGAGG GCATGTCTAA TAACAGCACC ACTAGCATCT CCCAAGCCAG GAAAGCTGTG 
GAGCAGCTAA AGATGGAAGC CTGTATGGAC AGGGTCAAGG TCTCCCAGGC AGCTGCGGAC 
CTCCTGGCCT ACTGTGAAGC TCACGTGCGG GAAGATCCTC TCATCATTCC AGTGCCTGCA 
TCAGAAAACC CCTTTCGCGA GAAGAAGTTC TTTTGTACCA TTCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001092191.1
CDS	329..556
Translation	MKEGMSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFREKKFFCTIL

Target ORF information:

RefSeq Version	NM_001098721.1
Organism	Homo sapiens(human)
Definition	Homo sapiens G protein subunit gamma 4 (GNG4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001098721.1

ORF Insert Sequence:

ATGAAAGAGG GCATGTCTAA TAACAGCACC ACTAGCATCT CCCAAGCCAG GAAAGCTGTG 
GAGCAGCTAA AGATGGAAGC CTGTATGGAC AGGGTCAAGG TCTCCCAGGC AGCTGCGGAC 
CTCCTGGCCT ACTGTGAAGC TCACGTGCGG GAAGATCCTC TCATCATTCC AGTGCCTGCA 
TCAGAAAACC CCTTTCGCGA GAAGAAGTTC TTTTGTACCA TTCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GNG4 ( NM_004485.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004476.1 Homo sapiens G protein subunit gamma 4 (GNG4), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu12701
Clone ID Related Accession (Same CDS sequence)	NM_001098721.1 , NM_001098722.2 , NM_004485.3 , NM_001098722.1 , NM_004485.4 , XM_006711761.2 , XM_011544167.2
Accession Version	NM_004485.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 228bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-20
Organism	Homo sapiens(human)
Product	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC022485.1, FO393422.1 and AK074383.1. On Jun 19, 2007 this sequence version replaced NM_004485.2. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC022485.1, BI669326.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2151119, SAMEA2155371 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAAGAGG GCATGTCTAA TAACAGCACC ACTAGCATCT CCCAAGCCAG GAAAGCTGTG 
GAGCAGCTAA AGATGGAAGC CTGTATGGAC AGGGTCAAGG TCTCCCAGGC AGCTGCGGAC 
CTCCTGGCCT ACTGTGAAGC TCACGTGCGG GAAGATCCTC TCATCATTCC AGTGCCTGCA 
TCAGAAAACC CCTTTCGCGA GAAGAAGTTC TTTTGTACCA TTCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004476.1
CDS	217..444
Translation	MKEGMSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFREKKFFCTIL

Target ORF information:

RefSeq Version	NM_004485.3
Organism	Homo sapiens(human)
Definition	Homo sapiens G protein subunit gamma 4 (GNG4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004485.3

ORF Insert Sequence:

ATGAAAGAGG GCATGTCTAA TAACAGCACC ACTAGCATCT CCCAAGCCAG GAAAGCTGTG 
GAGCAGCTAA AGATGGAAGC CTGTATGGAC AGGGTCAAGG TCTCCCAGGC AGCTGCGGAC 
CTCCTGGCCT ACTGTGAAGC TCACGTGCGG GAAGATCCTC TCATCATTCC AGTGCCTGCA 
TCAGAAAACC CCTTTCGCGA GAAGAAGTTC TTTTGTACCA TTCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GNG4 ( NM_001098722.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001092192.1 Homo sapiens G protein subunit gamma 4 (GNG4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu12701
Clone ID Related Accession (Same CDS sequence)	NM_001098721.1 , NM_001098722.2 , NM_004485.3 , NM_001098722.1 , NM_004485.4 , XM_006711761.2 , XM_011544167.2
Accession Version	NM_001098722.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 228bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB501745.1, CX784976.1, AK311781.1, FO393422.1 and AK074383.1. Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, and 3 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.20878.1, SRR1803615.130381.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAAGAGG GCATGTCTAA TAACAGCACC ACTAGCATCT CCCAAGCCAG GAAAGCTGTG 
GAGCAGCTAA AGATGGAAGC CTGTATGGAC AGGGTCAAGG TCTCCCAGGC AGCTGCGGAC 
CTCCTGGCCT ACTGTGAAGC TCACGTGCGG GAAGATCCTC TCATCATTCC AGTGCCTGCA 
TCAGAAAACC CCTTTCGCGA GAAGAAGTTC TTTTGTACCA TTCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001092192.1
CDS	455..682
Translation	MKEGMSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFREKKFFCTIL

Target ORF information:

RefSeq Version	NM_001098722.1
Organism	Homo sapiens(human)
Definition	Homo sapiens G protein subunit gamma 4 (GNG4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001098722.1

ORF Insert Sequence:

ATGAAAGAGG GCATGTCTAA TAACAGCACC ACTAGCATCT CCCAAGCCAG GAAAGCTGTG 
GAGCAGCTAA AGATGGAAGC CTGTATGGAC AGGGTCAAGG TCTCCCAGGC AGCTGCGGAC 
CTCCTGGCCT ACTGTGAAGC TCACGTGCGG GAAGATCCTC TCATCATTCC AGTGCCTGCA 
TCAGAAAACC CCTTTCGCGA GAAGAAGTTC TTTTGTACCA TTCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GNG4 ( NM_004485.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_004476.1 Homo sapiens G protein subunit gamma 4 (GNG4), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu12701
Clone ID Related Accession (Same CDS sequence)	NM_001098721.1 , NM_001098722.2 , NM_004485.3 , NM_001098722.1 , NM_004485.4 , XM_006711761.2 , XM_011544167.2
Accession Version	NM_004485.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 228bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-12
Organism	Homo sapiens(human)
Product	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC022485.1, FO393422.1 and AK074383.1. On May 31, 2019 this sequence version replaced NM_004485.3. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC022485.1, BI669326.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2151119, SAMEA2155371 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAAGAGG GCATGTCTAA TAACAGCACC ACTAGCATCT CCCAAGCCAG GAAAGCTGTG 
GAGCAGCTAA AGATGGAAGC CTGTATGGAC AGGGTCAAGG TCTCCCAGGC AGCTGCGGAC 
CTCCTGGCCT ACTGTGAAGC TCACGTGCGG GAAGATCCTC TCATCATTCC AGTGCCTGCA 
TCAGAAAACC CCTTTCGCGA GAAGAAGTTC TTTTGTACCA TTCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004476.1
CDS	71..298
Translation	MKEGMSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFREKKFFCTIL

Target ORF information:

RefSeq Version	NM_004485.4
Organism	Homo sapiens(human)
Definition	Homo sapiens G protein subunit gamma 4 (GNG4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004485.4

ORF Insert Sequence:

ATGAAAGAGG GCATGTCTAA TAACAGCACC ACTAGCATCT CCCAAGCCAG GAAAGCTGTG 
GAGCAGCTAA AGATGGAAGC CTGTATGGAC AGGGTCAAGG TCTCCCAGGC AGCTGCGGAC 
CTCCTGGCCT ACTGTGAAGC TCACGTGCGG GAAGATCCTC TCATCATTCC AGTGCCTGCA 
TCAGAAAACC CCTTTCGCGA GAAGAAGTTC TTTTGTACCA TTCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GNG4 ( XM_006711761.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006711824.1 Homo sapiens G protein subunit gamma 4 (GNG4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu12701
Clone ID Related Accession (Same CDS sequence)	NM_001098721.1 , NM_001098722.2 , NM_004485.3 , NM_001098722.1 , NM_004485.4 , XM_006711761.2 , XM_011544167.2
Accession Version	XM_006711761.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 228bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006711761.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAAGAGG GCATGTCTAA TAACAGCACC ACTAGCATCT CCCAAGCCAG GAAAGCTGTG 
GAGCAGCTAA AGATGGAAGC CTGTATGGAC AGGGTCAAGG TCTCCCAGGC AGCTGCGGAC 
CTCCTGGCCT ACTGTGAAGC TCACGTGCGG GAAGATCCTC TCATCATTCC AGTGCCTGCA 
TCAGAAAACC CCTTTCGCGA GAAGAAGTTC TTTTGTACCA TTCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006711824.1
CDS	100..327
Translation	MKEGMSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFREKKFFCTIL

Target ORF information:

RefSeq Version	XM_006711761.2
Organism	Homo sapiens(human)
Definition	Homo sapiens G protein subunit gamma 4 (GNG4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006711761.2

ORF Insert Sequence:

ATGAAAGAGG GCATGTCTAA TAACAGCACC ACTAGCATCT CCCAAGCCAG GAAAGCTGTG 
GAGCAGCTAA AGATGGAAGC CTGTATGGAC AGGGTCAAGG TCTCCCAGGC AGCTGCGGAC 
CTCCTGGCCT ACTGTGAAGC TCACGTGCGG GAAGATCCTC TCATCATTCC AGTGCCTGCA 
TCAGAAAACC CCTTTCGCGA GAAGAAGTTC TTTTGTACCA TTCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GNG4 ( XM_011544167.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011542469.1 Homo sapiens G protein subunit gamma 4 (GNG4), transcript variant X2, mRNA.

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CloneID	OHu12701
Clone ID Related Accession (Same CDS sequence)	NM_001098721.1 , NM_001098722.2 , NM_004485.3 , NM_001098722.1 , NM_004485.4 , XM_006711761.2 , XM_011544167.2
Accession Version	XM_011544167.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 228bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011544167.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAAGAGG GCATGTCTAA TAACAGCACC ACTAGCATCT CCCAAGCCAG GAAAGCTGTG 
GAGCAGCTAA AGATGGAAGC CTGTATGGAC AGGGTCAAGG TCTCCCAGGC AGCTGCGGAC 
CTCCTGGCCT ACTGTGAAGC TCACGTGCGG GAAGATCCTC TCATCATTCC AGTGCCTGCA 
TCAGAAAACC CCTTTCGCGA GAAGAAGTTC TTTTGTACCA TTCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011542469.1
CDS	30..257
Translation	MKEGMSNNSTTSISQARKAVEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFREKKFFCTIL

Target ORF information:

RefSeq Version	XM_011544167.2
Organism	Homo sapiens(human)
Definition	Homo sapiens G protein subunit gamma 4 (GNG4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011544167.2

ORF Insert Sequence:

ATGAAAGAGG GCATGTCTAA TAACAGCACC ACTAGCATCT CCCAAGCCAG GAAAGCTGTG 
GAGCAGCTAA AGATGGAAGC CTGTATGGAC AGGGTCAAGG TCTCCCAGGC AGCTGCGGAC 
CTCCTGGCCT ACTGTGAAGC TCACGTGCGG GAAGATCCTC TCATCATTCC AGTGCCTGCA 
TCAGAAAACC CCTTTCGCGA GAAGAAGTTC TTTTGTACCA TTCTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for GNG4 and KCNQ2 Genes.
American journal of Alzheimer's disease and other dementias1533317517739384(2018 Jan)
Bonham LW,Evans DS,Liu Y,Cummings SR,Yaffe K,Yokoyama JS

TREK-1 and Best1 channels mediate fast and slow glutamate release in astrocytes upon GPCR activation.
Cell151(1)25-40(2012 Sep)
Woo DH,Han KS,Shim JW,Yoon BE,Kim E,Bae JY,Oh SJ,Hwang EM,Marmorstein AD,Bae YC,Park JY,Lee CJ

Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study.
BMC medical genetics8 Suppl 1S13(2007 Sep)
Lunetta KL,D'Agostino RB Sr,Karasik D,Benjamin EJ,Guo CY,Govindaraju R,Kiel DP,Kelly-Hayes M,Massaro JM,Pencina MJ,Seshadri S,Murabito JM

Evidence for association of GABA(B) receptors with Kir3 channels and regulators of G protein signalling (RGS4) proteins.
The Journal of physiology580(Pt 1)51-65(2007 Apr)
Fowler CE,Aryal P,Suen KF,Slesinger PA

Identification of novel VHL target genes and relationship to hypoxic response pathways.
Oncogene24(28)4549-58(2005 Jun)
Maina EN,Morris MR,Zatyka M,Raval RR,Banks RE,Richards FM,Johnson CM,Maher ER

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GNG4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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Services & Products

見積依頼

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電話

FAX

オンラインフォーム