PYGO1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PYGO1
Entrez Gene ID	26108
Full Name	pygopus family PHD finger 1
General protein information	Preferred Names pygopus family PHD finger 1 Names pygopus homolog 1 pygopus-like protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q21.3
Disorder MIM:	606902

mRNA and Protein(s)

mRNA	Protein	Name
XM_011521446.2	XP_011519748.1	pygopus homolog 1 isoform X1
NM_001330326.2	NP_001317255.1	pygopus homolog 1 isoform 2
NM_015617.3	NP_056432.1	pygopus homolog 1 isoform 1
NM_015617.2	NP_056432.1	pygopus homolog 1 isoform 1
NM_001367806.1	NP_001354735.1	pygopus homolog 1 isoform 2
NM_001330326.1	NP_001317255.1	pygopus homolog 1 isoform 2

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	pygo1	NP_001107109.1
Xenopus tropicalis (tropical clawed frog)	pygo1	XP_002942500.2
	PYGO1	XP_001090005.2
Canis lupus familiaris (dog)	PYGO1	XP_005638747.1
Rattus norvegicus (Norway rat)	Pygo1	NP_001178046.1
Homo sapiens (human)	PYGO1	NP_056432.1
Bos taurus (cattle)	PYGO1	XP_002690938.1
Pan troglodytes (chimpanzee)	PYGO1	XP_523199.1
Mus musculus (house mouse)	Pygo1	NP_082392.1
Gallus gallus (chicken)	PYGO1	NP_001019862.1

Gene Ontology
Bibliography

Related articles in PubMed

Single nucleotide polymorphisms in Wnt signaling and cell death pathway genes and susceptibility to colorectal cancer.
Frank B, Hoffmeister M, Klopp N, Illig T, Chang-Claude J, Brenner H
Carcinogenesis31(8)1381-6(2010 Aug)

Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex.
Fiedler M, S?nchez-Barrena MJ, Nekrasov M, Mieszczanek J, Rybin V, M?ller J, Evans P, Bienz M
Molecular cell30(4)507-18(2008 May)

Pygopus residues required for its binding to Legless are critical for transcription and development.
Townsley FM, Thompson B, Bienz M
The Journal of biological chemistry279(7)5177-83(2004 Feb)

A new nuclear component of the Wnt signalling pathway.
Thompson B, Townsley F, Rosin-Arbesfeld R, Musisi H, Bienz M
Nature cell biology4(5)367-73(2002 May)

Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex.
Kramps T, Peter O, Brunner E, Nellen D, Froesch B, Chatterjee S, Murone M, Z?llig S, Basler K
Cell109(1)47-60(2002 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: Single nucleotide polymorphisms in Wnt signaling and cell death pathway genes and susceptibility to colorectal cancer.

Data show that human and Drosophila Pygo PHD fingers associate with their cognate HD1 domains from BCL9/Legless to bind specifically to the histone H3 tail methylated at lysine 4 (H3K4me).
Title: Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex.

The following PYGO1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PYGO1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu00380	NM_015617.3 Latest version!	Homo sapiens pygopus family PHD finger 1 (PYGO1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$244.30 $349.00
OHu48225	NM_001330326.2 Latest version!	Homo sapiens pygopus family PHD finger 1 (PYGO1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu48225	NM_001367806.1 Latest version!	Homo sapiens pygopus family PHD finger 1 (PYGO1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu48225	XM_011521446.2 Latest version!	Homo sapiens pygopus family PHD finger 1 (PYGO1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu00380	NM_015617.2	Homo sapiens pygopus family PHD finger 1 (PYGO1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$244.30 $349.00
OHu48225	NM_001330326.1	Homo sapiens pygopus family PHD finger 1 (PYGO1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PYGO1 ( NM_015617.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_056432.1 Homo sapiens pygopus family PHD finger 1 (PYGO1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu00380
Clone ID Related Accession (Same CDS sequence)	NM_015617.3 , NM_015617.2
Accession Version	NM_015617.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-06
Organism	Homo sapiens(human)
Product	pygopus homolog 1 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC012378.10, AF457207.1 and AC022083.6. On Dec 19, 2018 this sequence version replaced NM_015617.2. Transcript Variant: This variant (1) encodes isoform 1. Variants 1 and 2 encode isoforms that are the same length, but have distinct protein sequences. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.48348.1, SRR1803613.219019.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCCGCCG AGAACTCTCC AGCTCCCGCT TACAAAGTTT CCTCGCATGG TGGTGATAGT 
GGACTGGATG GGTTAGGAGG ACCAGGTGTA CAACTAGGAA GCCCAGATAA GAAAAAGCGC 
AAGGCAAATA CACAGGGACC TTCTTTCCCT CCATTGTCTG AGTATGCTCC ACCACCGAAT 
CCAAACTCTG ACCATCTAGT GGCTGCTAAT CCATTTGATG ACAACTATAA TACTATTTCC 
TATAAACCAC TACCTTCGTC AAATCCATAT CTTGGCCCTG GTTATCCTGG CTTTGGAGGC 
TATAGTACAT TCAGAATGCC ACCTCACGTT CCCCCAAGAA TGTCTTCCCC ATACTGTGGT 
CCTTACTCAC TCAGGAACCA GCCACACCCA TTTCCTCAGA ATCCTCTGGG CATGGGTTTT 
AATCGACCTC ATGCTTTTAA CTTTGGGCCA CATGATAATT CAAGTTTCGG TAATCCATCT 
TATAATAATG CACTAAGTCA GAATGTCAAC ATGCCTAATC AACATTTTAG ACAAAATCCT 
GCTGAAAATT TCAGTCAAAT TCCTCCACAG AATGCTAGCC AAGTTTCTAA CCCCGATTTG 
GCATCTAATT TTGTTCCTGG AAATAATTCA AATTTTACTT CTCCGTTAGA ATCTAATCAT 
TCTTTTATTC CTCCCCCAAA CACTTTTGGT CAAGCAAAAG CACCACCCCC AAAACAAGAC 
TTTACTCAAG GAGCAACCAA AAACACTAAT CAAAATTCCT CTGCTCATCC ACCTCACTTG 
AATATGGATG ACACAGTGAA TCAGAGTAAT ATTGAATTAA AAAATGTTAA TCGAAACAAT 
GCAGTAAATC AGGAGAACAG CCGTTCAAGT AGCACTGAAG CCACAAACAA TAACCCTGCA 
AATGGGACGC AGAATAAGCC ACGACAACCA AGAGGTGCAG CAGATGCCTG CACCACAGAA 
AAAAGCAATA AATCCTCTCT TCACCCAAAC CGTCATGGCC ATTCGTCTTC TGACCCAGTG 
TATCCTTGTG GAATTTGTAC AAACGAGGTG AACGATGATC AGGATGCCAT CTTATGTGAG 
GCCTCTTGTC AGAAATGGTT TCATCGGATC TGTACTGGAA TGACTGAAAC AGCTTATGGC 
CTCTTAACTG CAGAAGCATC TGCAGTATGG GGCTGTGATA CCTGTATGGC TGACAAAGAT 
GTCCAGTTAA TGCGTACTAG AGAAACTTTT GGTCCATCTG CAGTGGGCAG TGATGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056432.1
CDS	120..1379
Translation	MPAENSPAPAYKVSSHGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEYAPPPNPNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYCGPYSLRNQPHPFPQNPLGMGFNRPHAFNFGPHDNSSFGNPSYNNALSQNVNMPNQHFRQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPNTFGQAKAPPPKQDFTQGATKNTNQNSSAHPPHLNMDDTVNQSNIELKNVNRNNAVNQENSRSSSTEATNNNPANGTQNKPRQPRGAADACTTEKSNKSSLHPNRHGHSSSDPVYPCGICTNEVNDDQDAILCEASCQKWFHRICTGMTETAYGLLTAEASAVWGCDTCMADKDVQLMRTRETFGPSAVGSDA

Target ORF information:

RefSeq Version	NM_015617.3
Organism	Homo sapiens(human)
Definition	Homo sapiens pygopus family PHD finger 1 (PYGO1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015617.3

ORF Insert Sequence:

ATGCCCGCCG AGAACTCTCC AGCTCCCGCT TACAAAGTTT CCTCGCATGG TGGTGATAGT 
GGACTGGATG GGTTAGGAGG ACCAGGTGTA CAACTAGGAA GCCCAGATAA GAAAAAGCGC 
AAGGCAAATA CACAGGGACC TTCTTTCCCT CCATTGTCTG AGTATGCTCC ACCACCGAAT 
CCAAACTCTG ACCATCTAGT GGCTGCTAAT CCATTTGATG ACAACTATAA TACTATTTCC 
TATAAACCAC TACCTTCGTC AAATCCATAT CTTGGCCCTG GTTATCCTGG CTTTGGAGGC 
TATAGTACAT TCAGAATGCC ACCTCACGTT CCCCCAAGAA TGTCTTCCCC ATACTGTGGT 
CCTTACTCAC TCAGGAACCA GCCACACCCA TTTCCTCAGA ATCCTCTGGG CATGGGTTTT 
AATCGACCTC ATGCTTTTAA CTTTGGGCCA CATGATAATT CAAGTTTCGG TAATCCATCT 
TATAATAATG CACTAAGTCA GAATGTCAAC ATGCCTAATC AACATTTTAG ACAAAATCCT 
GCTGAAAATT TCAGTCAAAT TCCTCCACAG AATGCTAGCC AAGTTTCTAA CCCCGATTTG 
GCATCTAATT TTGTTCCTGG AAATAATTCA AATTTTACTT CTCCGTTAGA ATCTAATCAT 
TCTTTTATTC CTCCCCCAAA CACTTTTGGT CAAGCAAAAG CACCACCCCC AAAACAAGAC 
TTTACTCAAG GAGCAACCAA AAACACTAAT CAAAATTCCT CTGCTCATCC ACCTCACTTG 
AATATGGATG ACACAGTGAA TCAGAGTAAT ATTGAATTAA AAAATGTTAA TCGAAACAAT 
GCAGTAAATC AGGAGAACAG CCGTTCAAGT AGCACTGAAG CCACAAACAA TAACCCTGCA 
AATGGGACGC AGAATAAGCC ACGACAACCA AGAGGTGCAG CAGATGCCTG CACCACAGAA 
AAAAGCAATA AATCCTCTCT TCACCCAAAC CGTCATGGCC ATTCGTCTTC TGACCCAGTG 
TATCCTTGTG GAATTTGTAC AAACGAGGTG AACGATGATC AGGATGCCAT CTTATGTGAG 
GCCTCTTGTC AGAAATGGTT TCATCGGATC TGTACTGGAA TGACTGAAAC AGCTTATGGC 
CTCTTAACTG CAGAAGCATC TGCAGTATGG GGCTGTGATA CCTGTATGGC TGACAAAGAT 
GTCCAGTTAA TGCGTACTAG AGAAACTTTT GGTCCATCTG CAGTGGGCAG TGATGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PYGO1 ( NM_015617.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_056432.1 Homo sapiens pygopus family PHD finger 1 (PYGO1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu00380
Clone ID Related Accession (Same CDS sequence)	NM_015617.3 , NM_015617.2
Accession Version	NM_015617.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	pygopus homolog 1 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AF457207.1 and AC022083.6. On Dec 11, 2013 this sequence version replaced NM_015617.1. Transcript Variant: This variant (1) encodes isoform 1. Variants 1 and 2 encode isoforms that are the same length, but have distinct protein sequences. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AF457207.1, SRR1803614.48348.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCCGCCG AGAACTCTCC AGCTCCCGCT TACAAAGTTT CCTCGCATGG TGGTGATAGT 
GGACTGGATG GGTTAGGAGG ACCAGGTGTA CAACTAGGAA GCCCAGATAA GAAAAAGCGC 
AAGGCAAATA CACAGGGACC TTCTTTCCCT CCATTGTCTG AGTATGCTCC ACCACCGAAT 
CCAAACTCTG ACCATCTAGT GGCTGCTAAT CCATTTGATG ACAACTATAA TACTATTTCC 
TATAAACCAC TACCTTCGTC AAATCCATAT CTTGGCCCTG GTTATCCTGG CTTTGGAGGC 
TATAGTACAT TCAGAATGCC ACCTCACGTT CCCCCAAGAA TGTCTTCCCC ATACTGTGGT 
CCTTACTCAC TCAGGAACCA GCCACACCCA TTTCCTCAGA ATCCTCTGGG CATGGGTTTT 
AATCGACCTC ATGCTTTTAA CTTTGGGCCA CATGATAATT CAAGTTTCGG TAATCCATCT 
TATAATAATG CACTAAGTCA GAATGTCAAC ATGCCTAATC AACATTTTAG ACAAAATCCT 
GCTGAAAATT TCAGTCAAAT TCCTCCACAG AATGCTAGCC AAGTTTCTAA CCCCGATTTG 
GCATCTAATT TTGTTCCTGG AAATAATTCA AATTTTACTT CTCCGTTAGA ATCTAATCAT 
TCTTTTATTC CTCCCCCAAA CACTTTTGGT CAAGCAAAAG CACCACCCCC AAAACAAGAC 
TTTACTCAAG GAGCAACCAA AAACACTAAT CAAAATTCCT CTGCTCATCC ACCTCACTTG 
AATATGGATG ACACAGTGAA TCAGAGTAAT ATTGAATTAA AAAATGTTAA TCGAAACAAT 
GCAGTAAATC AGGAGAACAG CCGTTCAAGT AGCACTGAAG CCACAAACAA TAACCCTGCA 
AATGGGACGC AGAATAAGCC ACGACAACCA AGAGGTGCAG CAGATGCCTG CACCACAGAA 
AAAAGCAATA AATCCTCTCT TCACCCAAAC CGTCATGGCC ATTCGTCTTC TGACCCAGTG 
TATCCTTGTG GAATTTGTAC AAACGAGGTG AACGATGATC AGGATGCCAT CTTATGTGAG 
GCCTCTTGTC AGAAATGGTT TCATCGGATC TGTACTGGAA TGACTGAAAC AGCTTATGGC 
CTCTTAACTG CAGAAGCATC TGCAGTATGG GGCTGTGATA CCTGTATGGC TGACAAAGAT 
GTCCAGTTAA TGCGTACTAG AGAAACTTTT GGTCCATCTG CAGTGGGCAG TGATGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_056432.1
CDS	1..1260
Translation	MPAENSPAPAYKVSSHGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEYAPPPNPNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYCGPYSLRNQPHPFPQNPLGMGFNRPHAFNFGPHDNSSFGNPSYNNALSQNVNMPNQHFRQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPNTFGQAKAPPPKQDFTQGATKNTNQNSSAHPPHLNMDDTVNQSNIELKNVNRNNAVNQENSRSSSTEATNNNPANGTQNKPRQPRGAADACTTEKSNKSSLHPNRHGHSSSDPVYPCGICTNEVNDDQDAILCEASCQKWFHRICTGMTETAYGLLTAEASAVWGCDTCMADKDVQLMRTRETFGPSAVGSDA

Target ORF information:

RefSeq Version	NM_015617.2
Organism	Homo sapiens(human)
Definition	Homo sapiens pygopus family PHD finger 1 (PYGO1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_015617.2

ORF Insert Sequence:

ATGCCCGCCG AGAACTCTCC AGCTCCCGCT TACAAAGTTT CCTCGCATGG TGGTGATAGT 
GGACTGGATG GGTTAGGAGG ACCAGGTGTA CAACTAGGAA GCCCAGATAA GAAAAAGCGC 
AAGGCAAATA CACAGGGACC TTCTTTCCCT CCATTGTCTG AGTATGCTCC ACCACCGAAT 
CCAAACTCTG ACCATCTAGT GGCTGCTAAT CCATTTGATG ACAACTATAA TACTATTTCC 
TATAAACCAC TACCTTCGTC AAATCCATAT CTTGGCCCTG GTTATCCTGG CTTTGGAGGC 
TATAGTACAT TCAGAATGCC ACCTCACGTT CCCCCAAGAA TGTCTTCCCC ATACTGTGGT 
CCTTACTCAC TCAGGAACCA GCCACACCCA TTTCCTCAGA ATCCTCTGGG CATGGGTTTT 
AATCGACCTC ATGCTTTTAA CTTTGGGCCA CATGATAATT CAAGTTTCGG TAATCCATCT 
TATAATAATG CACTAAGTCA GAATGTCAAC ATGCCTAATC AACATTTTAG ACAAAATCCT 
GCTGAAAATT TCAGTCAAAT TCCTCCACAG AATGCTAGCC AAGTTTCTAA CCCCGATTTG 
GCATCTAATT TTGTTCCTGG AAATAATTCA AATTTTACTT CTCCGTTAGA ATCTAATCAT 
TCTTTTATTC CTCCCCCAAA CACTTTTGGT CAAGCAAAAG CACCACCCCC AAAACAAGAC 
TTTACTCAAG GAGCAACCAA AAACACTAAT CAAAATTCCT CTGCTCATCC ACCTCACTTG 
AATATGGATG ACACAGTGAA TCAGAGTAAT ATTGAATTAA AAAATGTTAA TCGAAACAAT 
GCAGTAAATC AGGAGAACAG CCGTTCAAGT AGCACTGAAG CCACAAACAA TAACCCTGCA 
AATGGGACGC AGAATAAGCC ACGACAACCA AGAGGTGCAG CAGATGCCTG CACCACAGAA 
AAAAGCAATA AATCCTCTCT TCACCCAAAC CGTCATGGCC ATTCGTCTTC TGACCCAGTG 
TATCCTTGTG GAATTTGTAC AAACGAGGTG AACGATGATC AGGATGCCAT CTTATGTGAG 
GCCTCTTGTC AGAAATGGTT TCATCGGATC TGTACTGGAA TGACTGAAAC AGCTTATGGC 
CTCTTAACTG CAGAAGCATC TGCAGTATGG GGCTGTGATA CCTGTATGGC TGACAAAGAT 
GTCCAGTTAA TGCGTACTAG AGAAACTTTT GGTCCATCTG CAGTGGGCAG TGATGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PYGO1 ( NM_001330326.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001317255.1 Homo sapiens pygopus family PHD finger 1 (PYGO1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu48225
Clone ID Related Accession (Same CDS sequence)	XM_011521446.2 , NM_001330326.2 , NM_001367806.1 , NM_001330326.1
Accession Version	NM_001330326.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Homo sapiens(human)
Product	pygopus homolog 1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC012378.10 and AC022083.6. On Dec 19, 2018 this sequence version replaced NM_001330326.1. Transcript Variant: This variant (2) differs in the 5' and 3' UTRs, and uses an alternate start codon, compared to variant 1. The encoded isoform (2) is the same length as isoform 1, but has a distinct N-terminus. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.26301.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCAGCAG AACAGGAGAA GGATCCCATT TCGCTGAAGA GAGTTCGAGG TGGTGATAGT 
GGACTGGATG GGTTAGGAGG ACCAGGTGTA CAACTAGGAA GCCCAGATAA GAAAAAGCGC 
AAGGCAAATA CACAGGGACC TTCTTTCCCT CCATTGTCTG AGTATGCTCC ACCACCGAAT 
CCAAACTCTG ACCATCTAGT GGCTGCTAAT CCATTTGATG ACAACTATAA TACTATTTCC 
TATAAACCAC TACCTTCGTC AAATCCATAT CTTGGCCCTG GTTATCCTGG CTTTGGAGGC 
TATAGTACAT TCAGAATGCC ACCTCACGTT CCCCCAAGAA TGTCTTCCCC ATACTGTGGT 
CCTTACTCAC TCAGGAACCA GCCACACCCA TTTCCTCAGA ATCCTCTGGG CATGGGTTTT 
AATCGACCTC ATGCTTTTAA CTTTGGGCCA CATGATAATT CAAGTTTCGG TAATCCATCT 
TATAATAATG CACTAAGTCA GAATGTCAAC ATGCCTAATC AACATTTTAG ACAAAATCCT 
GCTGAAAATT TCAGTCAAAT TCCTCCACAG AATGCTAGCC AAGTTTCTAA CCCCGATTTG 
GCATCTAATT TTGTTCCTGG AAATAATTCA AATTTTACTT CTCCGTTAGA ATCTAATCAT 
TCTTTTATTC CTCCCCCAAA CACTTTTGGT CAAGCAAAAG CACCACCCCC AAAACAAGAC 
TTTACTCAAG GAGCAACCAA AAACACTAAT CAAAATTCCT CTGCTCATCC ACCTCACTTG 
AATATGGATG ACACAGTGAA TCAGAGTAAT ATTGAATTAA AAAATGTTAA TCGAAACAAT 
GCAGTAAATC AGGAGAACAG CCGTTCAAGT AGCACTGAAG CCACAAACAA TAACCCTGCA 
AATGGGACGC AGAATAAGCC ACGACAACCA AGAGGTGCAG CAGATGCCTG CACCACAGAA 
AAAAGCAATA AATCCTCTCT TCACCCAAAC CGTCATGGCC ATTCGTCTTC TGACCCAGTG 
TATCCTTGTG GAATTTGTAC AAACGAGGTG AACGATGATC AGGATGCCAT CTTATGTGAG 
GCCTCTTGTC AGAAATGGTT TCATCGGATC TGTACTGGAA TGACTGAAAC AGCTTATGGC 
CTCTTAACTG CAGAAGCATC TGCAGTATGG GGCTGTGATA CCTGTATGGC TGACAAAGAT 
GTCCAGTTAA TGCGTACTAG AGAAACTTTT GGTCCATCTG CAGTGGGCAG TGATGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001317255.1
CDS	463..1722
Translation	MSAEQEKDPISLKRVRGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEYAPPPNPNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYCGPYSLRNQPHPFPQNPLGMGFNRPHAFNFGPHDNSSFGNPSYNNALSQNVNMPNQHFRQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPNTFGQAKAPPPKQDFTQGATKNTNQNSSAHPPHLNMDDTVNQSNIELKNVNRNNAVNQENSRSSSTEATNNNPANGTQNKPRQPRGAADACTTEKSNKSSLHPNRHGHSSSDPVYPCGICTNEVNDDQDAILCEASCQKWFHRICTGMTETAYGLLTAEASAVWGCDTCMADKDVQLMRTRETFGPSAVGSDA

Target ORF information:

RefSeq Version	NM_001330326.2
Organism	Homo sapiens(human)
Definition	Homo sapiens pygopus family PHD finger 1 (PYGO1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001330326.2

ORF Insert Sequence:

ATGTCAGCAG AACAGGAGAA GGATCCCATT TCGCTGAAGA GAGTTCGAGG TGGTGATAGT 
GGACTGGATG GGTTAGGAGG ACCAGGTGTA CAACTAGGAA GCCCAGATAA GAAAAAGCGC 
AAGGCAAATA CACAGGGACC TTCTTTCCCT CCATTGTCTG AGTATGCTCC ACCACCGAAT 
CCAAACTCTG ACCATCTAGT GGCTGCTAAT CCATTTGATG ACAACTATAA TACTATTTCC 
TATAAACCAC TACCTTCGTC AAATCCATAT CTTGGCCCTG GTTATCCTGG CTTTGGAGGC 
TATAGTACAT TCAGAATGCC ACCTCACGTT CCCCCAAGAA TGTCTTCCCC ATACTGTGGT 
CCTTACTCAC TCAGGAACCA GCCACACCCA TTTCCTCAGA ATCCTCTGGG CATGGGTTTT 
AATCGACCTC ATGCTTTTAA CTTTGGGCCA CATGATAATT CAAGTTTCGG TAATCCATCT 
TATAATAATG CACTAAGTCA GAATGTCAAC ATGCCTAATC AACATTTTAG ACAAAATCCT 
GCTGAAAATT TCAGTCAAAT TCCTCCACAG AATGCTAGCC AAGTTTCTAA CCCCGATTTG 
GCATCTAATT TTGTTCCTGG AAATAATTCA AATTTTACTT CTCCGTTAGA ATCTAATCAT 
TCTTTTATTC CTCCCCCAAA CACTTTTGGT CAAGCAAAAG CACCACCCCC AAAACAAGAC 
TTTACTCAAG GAGCAACCAA AAACACTAAT CAAAATTCCT CTGCTCATCC ACCTCACTTG 
AATATGGATG ACACAGTGAA TCAGAGTAAT ATTGAATTAA AAAATGTTAA TCGAAACAAT 
GCAGTAAATC AGGAGAACAG CCGTTCAAGT AGCACTGAAG CCACAAACAA TAACCCTGCA 
AATGGGACGC AGAATAAGCC ACGACAACCA AGAGGTGCAG CAGATGCCTG CACCACAGAA 
AAAAGCAATA AATCCTCTCT TCACCCAAAC CGTCATGGCC ATTCGTCTTC TGACCCAGTG 
TATCCTTGTG GAATTTGTAC AAACGAGGTG AACGATGATC AGGATGCCAT CTTATGTGAG 
GCCTCTTGTC AGAAATGGTT TCATCGGATC TGTACTGGAA TGACTGAAAC AGCTTATGGC 
CTCTTAACTG CAGAAGCATC TGCAGTATGG GGCTGTGATA CCTGTATGGC TGACAAAGAT 
GTCCAGTTAA TGCGTACTAG AGAAACTTTT GGTCCATCTG CAGTGGGCAG TGATGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PYGO1 ( NM_001367806.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001354735.1 Homo sapiens pygopus family PHD finger 1 (PYGO1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu48225
Clone ID Related Accession (Same CDS sequence)	XM_011521446.2 , NM_001330326.2 , NM_001367806.1 , NM_001330326.1
Accession Version	NM_001367806.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Homo sapiens(human)
Product	pygopus homolog 1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC012378.10 and AC022083.6. On Dec 19, 2018 this sequence version replaced XM_011521446.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.153189.1, SRR1803617.351206.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTCAGCAG AACAGGAGAA GGATCCCATT TCGCTGAAGA GAGTTCGAGG TGGTGATAGT 
GGACTGGATG GGTTAGGAGG ACCAGGTGTA CAACTAGGAA GCCCAGATAA GAAAAAGCGC 
AAGGCAAATA CACAGGGACC TTCTTTCCCT CCATTGTCTG AGTATGCTCC ACCACCGAAT 
CCAAACTCTG ACCATCTAGT GGCTGCTAAT CCATTTGATG ACAACTATAA TACTATTTCC 
TATAAACCAC TACCTTCGTC AAATCCATAT CTTGGCCCTG GTTATCCTGG CTTTGGAGGC 
TATAGTACAT TCAGAATGCC ACCTCACGTT CCCCCAAGAA TGTCTTCCCC ATACTGTGGT 
CCTTACTCAC TCAGGAACCA GCCACACCCA TTTCCTCAGA ATCCTCTGGG CATGGGTTTT 
AATCGACCTC ATGCTTTTAA CTTTGGGCCA CATGATAATT CAAGTTTCGG TAATCCATCT 
TATAATAATG CACTAAGTCA GAATGTCAAC ATGCCTAATC AACATTTTAG ACAAAATCCT 
GCTGAAAATT TCAGTCAAAT TCCTCCACAG AATGCTAGCC AAGTTTCTAA CCCCGATTTG 
GCATCTAATT TTGTTCCTGG AAATAATTCA AATTTTACTT CTCCGTTAGA ATCTAATCAT 
TCTTTTATTC CTCCCCCAAA CACTTTTGGT CAAGCAAAAG CACCACCCCC AAAACAAGAC 
TTTACTCAAG GAGCAACCAA AAACACTAAT CAAAATTCCT CTGCTCATCC ACCTCACTTG 
AATATGGATG ACACAGTGAA TCAGAGTAAT ATTGAATTAA AAAATGTTAA TCGAAACAAT 
GCAGTAAATC AGGAGAACAG CCGTTCAAGT AGCACTGAAG CCACAAACAA TAACCCTGCA 
AATGGGACGC AGAATAAGCC ACGACAACCA AGAGGTGCAG CAGATGCCTG CACCACAGAA 
AAAAGCAATA AATCCTCTCT TCACCCAAAC CGTCATGGCC ATTCGTCTTC TGACCCAGTG 
TATCCTTGTG GAATTTGTAC AAACGAGGTG AACGATGATC AGGATGCCAT CTTATGTGAG 
GCCTCTTGTC AGAAATGGTT TCATCGGATC TGTACTGGAA TGACTGAAAC AGCTTATGGC 
CTCTTAACTG CAGAAGCATC TGCAGTATGG GGCTGTGATA CCTGTATGGC TGACAAAGAT 
GTCCAGTTAA TGCGTACTAG AGAAACTTTT GGTCCATCTG CAGTGGGCAG TGATGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001354735.1
CDS	463..1722
Translation	MSAEQEKDPISLKRVRGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEYAPPPNPNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYCGPYSLRNQPHPFPQNPLGMGFNRPHAFNFGPHDNSSFGNPSYNNALSQNVNMPNQHFRQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPNTFGQAKAPPPKQDFTQGATKNTNQNSSAHPPHLNMDDTVNQSNIELKNVNRNNAVNQENSRSSSTEATNNNPANGTQNKPRQPRGAADACTTEKSNKSSLHPNRHGHSSSDPVYPCGICTNEVNDDQDAILCEASCQKWFHRICTGMTETAYGLLTAEASAVWGCDTCMADKDVQLMRTRETFGPSAVGSDA

Target ORF information:

RefSeq Version	NM_001367806.1
Organism	Homo sapiens(human)
Definition	Homo sapiens pygopus family PHD finger 1 (PYGO1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001367806.1

ORF Insert Sequence:

ATGTCAGCAG AACAGGAGAA GGATCCCATT TCGCTGAAGA GAGTTCGAGG TGGTGATAGT 
GGACTGGATG GGTTAGGAGG ACCAGGTGTA CAACTAGGAA GCCCAGATAA GAAAAAGCGC 
AAGGCAAATA CACAGGGACC TTCTTTCCCT CCATTGTCTG AGTATGCTCC ACCACCGAAT 
CCAAACTCTG ACCATCTAGT GGCTGCTAAT CCATTTGATG ACAACTATAA TACTATTTCC 
TATAAACCAC TACCTTCGTC AAATCCATAT CTTGGCCCTG GTTATCCTGG CTTTGGAGGC 
TATAGTACAT TCAGAATGCC ACCTCACGTT CCCCCAAGAA TGTCTTCCCC ATACTGTGGT 
CCTTACTCAC TCAGGAACCA GCCACACCCA TTTCCTCAGA ATCCTCTGGG CATGGGTTTT 
AATCGACCTC ATGCTTTTAA CTTTGGGCCA CATGATAATT CAAGTTTCGG TAATCCATCT 
TATAATAATG CACTAAGTCA GAATGTCAAC ATGCCTAATC AACATTTTAG ACAAAATCCT 
GCTGAAAATT TCAGTCAAAT TCCTCCACAG AATGCTAGCC AAGTTTCTAA CCCCGATTTG 
GCATCTAATT TTGTTCCTGG AAATAATTCA AATTTTACTT CTCCGTTAGA ATCTAATCAT 
TCTTTTATTC CTCCCCCAAA CACTTTTGGT CAAGCAAAAG CACCACCCCC AAAACAAGAC 
TTTACTCAAG GAGCAACCAA AAACACTAAT CAAAATTCCT CTGCTCATCC ACCTCACTTG 
AATATGGATG ACACAGTGAA TCAGAGTAAT ATTGAATTAA AAAATGTTAA TCGAAACAAT 
GCAGTAAATC AGGAGAACAG CCGTTCAAGT AGCACTGAAG CCACAAACAA TAACCCTGCA 
AATGGGACGC AGAATAAGCC ACGACAACCA AGAGGTGCAG CAGATGCCTG CACCACAGAA 
AAAAGCAATA AATCCTCTCT TCACCCAAAC CGTCATGGCC ATTCGTCTTC TGACCCAGTG 
TATCCTTGTG GAATTTGTAC AAACGAGGTG AACGATGATC AGGATGCCAT CTTATGTGAG 
GCCTCTTGTC AGAAATGGTT TCATCGGATC TGTACTGGAA TGACTGAAAC AGCTTATGGC 
CTCTTAACTG CAGAAGCATC TGCAGTATGG GGCTGTGATA CCTGTATGGC TGACAAAGAT 
GTCCAGTTAA TGCGTACTAG AGAAACTTTT GGTCCATCTG CAGTGGGCAG TGATGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PYGO1 ( NM_001330326.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001317255.1 Homo sapiens pygopus family PHD finger 1 (PYGO1), transcript variant 2, mRNA.

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CloneID	OHu48225
Clone ID Related Accession (Same CDS sequence)	XM_011521446.2 , NM_001330326.2 , NM_001367806.1 , NM_001330326.1
Accession Version	NM_001330326.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-03
Organism	Homo sapiens(human)
Product	pygopus homolog 1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC012378.10 and AC022083.6. On Aug 23, 2016 this sequence version replaced XM_005254300.4. Transcript Variant: This variant (2) differs in the 5' and 3' UTRs, and uses an alternate start codon, compared to variant 1. The encoded isoform (2) is the same length as isoform 1, but has a distinct N-terminus. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.26301.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCAGCAG AACAGGAGAA GGATCCCATT TCGCTGAAGA GAGTTCGAGG TGGTGATAGT 
GGACTGGATG GGTTAGGAGG ACCAGGTGTA CAACTAGGAA GCCCAGATAA GAAAAAGCGC 
AAGGCAAATA CACAGGGACC TTCTTTCCCT CCATTGTCTG AGTATGCTCC ACCACCGAAT 
CCAAACTCTG ACCATCTAGT GGCTGCTAAT CCATTTGATG ACAACTATAA TACTATTTCC 
TATAAACCAC TACCTTCGTC AAATCCATAT CTTGGCCCTG GTTATCCTGG CTTTGGAGGC 
TATAGTACAT TCAGAATGCC ACCTCACGTT CCCCCAAGAA TGTCTTCCCC ATACTGTGGT 
CCTTACTCAC TCAGGAACCA GCCACACCCA TTTCCTCAGA ATCCTCTGGG CATGGGTTTT 
AATCGACCTC ATGCTTTTAA CTTTGGGCCA CATGATAATT CAAGTTTCGG TAATCCATCT 
TATAATAATG CACTAAGTCA GAATGTCAAC ATGCCTAATC AACATTTTAG ACAAAATCCT 
GCTGAAAATT TCAGTCAAAT TCCTCCACAG AATGCTAGCC AAGTTTCTAA CCCCGATTTG 
GCATCTAATT TTGTTCCTGG AAATAATTCA AATTTTACTT CTCCGTTAGA ATCTAATCAT 
TCTTTTATTC CTCCCCCAAA CACTTTTGGT CAAGCAAAAG CACCACCCCC AAAACAAGAC 
TTTACTCAAG GAGCAACCAA AAACACTAAT CAAAATTCCT CTGCTCATCC ACCTCACTTG 
AATATGGATG ACACAGTGAA TCAGAGTAAT ATTGAATTAA AAAATGTTAA TCGAAACAAT 
GCAGTAAATC AGGAGAACAG CCGTTCAAGT AGCACTGAAG CCACAAACAA TAACCCTGCA 
AATGGGACGC AGAATAAGCC ACGACAACCA AGAGGTGCAG CAGATGCCTG CACCACAGAA 
AAAAGCAATA AATCCTCTCT TCACCCAAAC CGTCATGGCC ATTCGTCTTC TGACCCAGTG 
TATCCTTGTG GAATTTGTAC AAACGAGGTG AACGATGATC AGGATGCCAT CTTATGTGAG 
GCCTCTTGTC AGAAATGGTT TCATCGGATC TGTACTGGAA TGACTGAAAC AGCTTATGGC 
CTCTTAACTG CAGAAGCATC TGCAGTATGG GGCTGTGATA CCTGTATGGC TGACAAAGAT 
GTCCAGTTAA TGCGTACTAG AGAAACTTTT GGTCCATCTG CAGTGGGCAG TGATGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001317255.1
CDS	96..1355
Translation	MSAEQEKDPISLKRVRGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEYAPPPNPNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYCGPYSLRNQPHPFPQNPLGMGFNRPHAFNFGPHDNSSFGNPSYNNALSQNVNMPNQHFRQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPNTFGQAKAPPPKQDFTQGATKNTNQNSSAHPPHLNMDDTVNQSNIELKNVNRNNAVNQENSRSSSTEATNNNPANGTQNKPRQPRGAADACTTEKSNKSSLHPNRHGHSSSDPVYPCGICTNEVNDDQDAILCEASCQKWFHRICTGMTETAYGLLTAEASAVWGCDTCMADKDVQLMRTRETFGPSAVGSDA

Target ORF information:

RefSeq Version	NM_001330326.1
Organism	Homo sapiens(human)
Definition	Homo sapiens pygopus family PHD finger 1 (PYGO1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001330326.1

ORF Insert Sequence:

ATGTCAGCAG AACAGGAGAA GGATCCCATT TCGCTGAAGA GAGTTCGAGG TGGTGATAGT 
GGACTGGATG GGTTAGGAGG ACCAGGTGTA CAACTAGGAA GCCCAGATAA GAAAAAGCGC 
AAGGCAAATA CACAGGGACC TTCTTTCCCT CCATTGTCTG AGTATGCTCC ACCACCGAAT 
CCAAACTCTG ACCATCTAGT GGCTGCTAAT CCATTTGATG ACAACTATAA TACTATTTCC 
TATAAACCAC TACCTTCGTC AAATCCATAT CTTGGCCCTG GTTATCCTGG CTTTGGAGGC 
TATAGTACAT TCAGAATGCC ACCTCACGTT CCCCCAAGAA TGTCTTCCCC ATACTGTGGT 
CCTTACTCAC TCAGGAACCA GCCACACCCA TTTCCTCAGA ATCCTCTGGG CATGGGTTTT 
AATCGACCTC ATGCTTTTAA CTTTGGGCCA CATGATAATT CAAGTTTCGG TAATCCATCT 
TATAATAATG CACTAAGTCA GAATGTCAAC ATGCCTAATC AACATTTTAG ACAAAATCCT 
GCTGAAAATT TCAGTCAAAT TCCTCCACAG AATGCTAGCC AAGTTTCTAA CCCCGATTTG 
GCATCTAATT TTGTTCCTGG AAATAATTCA AATTTTACTT CTCCGTTAGA ATCTAATCAT 
TCTTTTATTC CTCCCCCAAA CACTTTTGGT CAAGCAAAAG CACCACCCCC AAAACAAGAC 
TTTACTCAAG GAGCAACCAA AAACACTAAT CAAAATTCCT CTGCTCATCC ACCTCACTTG 
AATATGGATG ACACAGTGAA TCAGAGTAAT ATTGAATTAA AAAATGTTAA TCGAAACAAT 
GCAGTAAATC AGGAGAACAG CCGTTCAAGT AGCACTGAAG CCACAAACAA TAACCCTGCA 
AATGGGACGC AGAATAAGCC ACGACAACCA AGAGGTGCAG CAGATGCCTG CACCACAGAA 
AAAAGCAATA AATCCTCTCT TCACCCAAAC CGTCATGGCC ATTCGTCTTC TGACCCAGTG 
TATCCTTGTG GAATTTGTAC AAACGAGGTG AACGATGATC AGGATGCCAT CTTATGTGAG 
GCCTCTTGTC AGAAATGGTT TCATCGGATC TGTACTGGAA TGACTGAAAC AGCTTATGGC 
CTCTTAACTG CAGAAGCATC TGCAGTATGG GGCTGTGATA CCTGTATGGC TGACAAAGAT 
GTCCAGTTAA TGCGTACTAG AGAAACTTTT GGTCCATCTG CAGTGGGCAG TGATGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PYGO1 ( XM_011521446.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011519748.1 Homo sapiens pygopus family PHD finger 1 (PYGO1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu48225
Clone ID Related Accession (Same CDS sequence)	XM_011521446.2 , NM_001330326.2 , NM_001367806.1 , NM_001330326.1
Accession Version	XM_011521446.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1260bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	pygopus homolog 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000015.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011521446.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCAGCAG AACAGGAGAA GGATCCCATT TCGCTGAAGA GAGTTCGAGG TGGTGATAGT 
GGACTGGATG GGTTAGGAGG ACCAGGTGTA CAACTAGGAA GCCCAGATAA GAAAAAGCGC 
AAGGCAAATA CACAGGGACC TTCTTTCCCT CCATTGTCTG AGTATGCTCC ACCACCGAAT 
CCAAACTCTG ACCATCTAGT GGCTGCTAAT CCATTTGATG ACAACTATAA TACTATTTCC 
TATAAACCAC TACCTTCGTC AAATCCATAT CTTGGCCCTG GTTATCCTGG CTTTGGAGGC 
TATAGTACAT TCAGAATGCC ACCTCACGTT CCCCCAAGAA TGTCTTCCCC ATACTGTGGT 
CCTTACTCAC TCAGGAACCA GCCACACCCA TTTCCTCAGA ATCCTCTGGG CATGGGTTTT 
AATCGACCTC ATGCTTTTAA CTTTGGGCCA CATGATAATT CAAGTTTCGG TAATCCATCT 
TATAATAATG CACTAAGTCA GAATGTCAAC ATGCCTAATC AACATTTTAG ACAAAATCCT 
GCTGAAAATT TCAGTCAAAT TCCTCCACAG AATGCTAGCC AAGTTTCTAA CCCCGATTTG 
GCATCTAATT TTGTTCCTGG AAATAATTCA AATTTTACTT CTCCGTTAGA ATCTAATCAT 
TCTTTTATTC CTCCCCCAAA CACTTTTGGT CAAGCAAAAG CACCACCCCC AAAACAAGAC 
TTTACTCAAG GAGCAACCAA AAACACTAAT CAAAATTCCT CTGCTCATCC ACCTCACTTG 
AATATGGATG ACACAGTGAA TCAGAGTAAT ATTGAATTAA AAAATGTTAA TCGAAACAAT 
GCAGTAAATC AGGAGAACAG CCGTTCAAGT AGCACTGAAG CCACAAACAA TAACCCTGCA 
AATGGGACGC AGAATAAGCC ACGACAACCA AGAGGTGCAG CAGATGCCTG CACCACAGAA 
AAAAGCAATA AATCCTCTCT TCACCCAAAC CGTCATGGCC ATTCGTCTTC TGACCCAGTG 
TATCCTTGTG GAATTTGTAC AAACGAGGTG AACGATGATC AGGATGCCAT CTTATGTGAG 
GCCTCTTGTC AGAAATGGTT TCATCGGATC TGTACTGGAA TGACTGAAAC AGCTTATGGC 
CTCTTAACTG CAGAAGCATC TGCAGTATGG GGCTGTGATA CCTGTATGGC TGACAAAGAT 
GTCCAGTTAA TGCGTACTAG AGAAACTTTT GGTCCATCTG CAGTGGGCAG TGATGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011519748.1
CDS	396..1655
Translation	MSAEQEKDPISLKRVRGGDSGLDGLGGPGVQLGSPDKKKRKANTQGPSFPPLSEYAPPPNPNSDHLVAANPFDDNYNTISYKPLPSSNPYLGPGYPGFGGYSTFRMPPHVPPRMSSPYCGPYSLRNQPHPFPQNPLGMGFNRPHAFNFGPHDNSSFGNPSYNNALSQNVNMPNQHFRQNPAENFSQIPPQNASQVSNPDLASNFVPGNNSNFTSPLESNHSFIPPPNTFGQAKAPPPKQDFTQGATKNTNQNSSAHPPHLNMDDTVNQSNIELKNVNRNNAVNQENSRSSSTEATNNNPANGTQNKPRQPRGAADACTTEKSNKSSLHPNRHGHSSSDPVYPCGICTNEVNDDQDAILCEASCQKWFHRICTGMTETAYGLLTAEASAVWGCDTCMADKDVQLMRTRETFGPSAVGSDA

Target ORF information:

RefSeq Version	XM_011521446.2
Organism	Homo sapiens(human)
Definition	Homo sapiens pygopus family PHD finger 1 (PYGO1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011521446.2

ORF Insert Sequence:

ATGTCAGCAG AACAGGAGAA GGATCCCATT TCGCTGAAGA GAGTTCGAGG TGGTGATAGT 
GGACTGGATG GGTTAGGAGG ACCAGGTGTA CAACTAGGAA GCCCAGATAA GAAAAAGCGC 
AAGGCAAATA CACAGGGACC TTCTTTCCCT CCATTGTCTG AGTATGCTCC ACCACCGAAT 
CCAAACTCTG ACCATCTAGT GGCTGCTAAT CCATTTGATG ACAACTATAA TACTATTTCC 
TATAAACCAC TACCTTCGTC AAATCCATAT CTTGGCCCTG GTTATCCTGG CTTTGGAGGC 
TATAGTACAT TCAGAATGCC ACCTCACGTT CCCCCAAGAA TGTCTTCCCC ATACTGTGGT 
CCTTACTCAC TCAGGAACCA GCCACACCCA TTTCCTCAGA ATCCTCTGGG CATGGGTTTT 
AATCGACCTC ATGCTTTTAA CTTTGGGCCA CATGATAATT CAAGTTTCGG TAATCCATCT 
TATAATAATG CACTAAGTCA GAATGTCAAC ATGCCTAATC AACATTTTAG ACAAAATCCT 
GCTGAAAATT TCAGTCAAAT TCCTCCACAG AATGCTAGCC AAGTTTCTAA CCCCGATTTG 
GCATCTAATT TTGTTCCTGG AAATAATTCA AATTTTACTT CTCCGTTAGA ATCTAATCAT 
TCTTTTATTC CTCCCCCAAA CACTTTTGGT CAAGCAAAAG CACCACCCCC AAAACAAGAC 
TTTACTCAAG GAGCAACCAA AAACACTAAT CAAAATTCCT CTGCTCATCC ACCTCACTTG 
AATATGGATG ACACAGTGAA TCAGAGTAAT ATTGAATTAA AAAATGTTAA TCGAAACAAT 
GCAGTAAATC AGGAGAACAG CCGTTCAAGT AGCACTGAAG CCACAAACAA TAACCCTGCA 
AATGGGACGC AGAATAAGCC ACGACAACCA AGAGGTGCAG CAGATGCCTG CACCACAGAA 
AAAAGCAATA AATCCTCTCT TCACCCAAAC CGTCATGGCC ATTCGTCTTC TGACCCAGTG 
TATCCTTGTG GAATTTGTAC AAACGAGGTG AACGATGATC AGGATGCCAT CTTATGTGAG 
GCCTCTTGTC AGAAATGGTT TCATCGGATC TGTACTGGAA TGACTGAAAC AGCTTATGGC 
CTCTTAACTG CAGAAGCATC TGCAGTATGG GGCTGTGATA CCTGTATGGC TGACAAAGAT 
GTCCAGTTAA TGCGTACTAG AGAAACTTTT GGTCCATCTG CAGTGGGCAG TGATGCTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Single nucleotide polymorphisms in Wnt signaling and cell death pathway genes and susceptibility to colorectal cancer.
Carcinogenesis31(8)1381-6(2010 Aug)
Frank B,Hoffmeister M,Klopp N,Illig T,Chang-Claude J,Brenner H

Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex.
Molecular cell30(4)507-18(2008 May)
Fiedler M,S?nchez-Barrena MJ,Nekrasov M,Mieszczanek J,Rybin V,M?ller J,Evans P,Bienz M

Pygopus residues required for its binding to Legless are critical for transcription and development.
The Journal of biological chemistry279(7)5177-83(2004 Feb)
Townsley FM,Thompson B,Bienz M

A new nuclear component of the Wnt signalling pathway.
Nature cell biology4(5)367-73(2002 May)
Thompson B,Townsley F,Rosin-Arbesfeld R,Musisi H,Bienz M

Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex.
Cell109(1)47-60(2002 Apr)
Kramps T,Peter O,Brunner E,Nellen D,Froesch B,Chatterjee S,Murone M,Z?llig S,Basler K

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PYGO1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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