TAS2R19 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TAS2R19
Entrez Gene ID	259294
Full Name	taste 2 receptor member 19
Synonyms	MSTP058,T2R19,T2R23,T2R48,TAS2R23,TAS2R48
General protein information	Preferred Names taste 2 receptor member 19 Names taste receptor type 2 member 19 taste receptor, type 2, member 19 taste receptor, type 2, member 23 taste receptor, type 2, member 48
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12p13.2
Disorder MIM:	613961

mRNA and Protein(s)

mRNA	Protein	Name
NM_176888.2	NP_795369.1	taste receptor type 2 member 19

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	TAS2R19	XP_003313544.1
Homo sapiens (human)	TAS2R19	NP_795369.1

Gene Ontology
Bibliography

Related articles in PubMed

The perception of quinine taste intensity is associated with common genetic variants in a bitter receptor cluster on chromosome 12.
Reed DR, Zhu G, Breslin PA, Duke FF, Henders AK, Campbell MJ, Montgomery GW, Medland SE, Martin NG, Wright MJ
Human molecular genetics19(21)4278-85(2010 Nov)

The molecular receptive ranges of human TAS2R bitter taste receptors.
Meyerhof W, Batram C, Kuhn C, Brockhoff A, Chudoba E, Bufe B, Appendino G, Behrens M
Chemical senses35(2)157-70(2010 Feb)

Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.
Go Y, Satta Y, Takenaka O, Takahata N
Genetics170(1)313-26(2005 May)

Evolution of bitter taste receptors in humans and apes.
Fischer A, Gilad Y, Man O, P??bo S
Molecular biology and evolution22(3)432-6(2005 Mar)

Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.
Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ
Cell112(3)293-301(2003 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
Title: The perception of quinine taste intensity is associated with common genetic variants in a bitter receptor cluster on chromosome 12.

The following TAS2R19 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TAS2R19 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu78483	NM_176888.2 Latest version!	Homo sapiens taste 2 receptor member 19 (TAS2R19), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TAS2R19 ( NM_176888.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_795369.1 Homo sapiens taste 2 receptor member 19 (TAS2R19), mRNA.

Price & Availability↑

CloneID	OHu78483
Clone ID Related Accession (Same CDS sequence)	NM_176888.2
Accession Version	NM_176888.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 900bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Homo sapiens(human)
Product	taste receptor type 2 member 19
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC101804.1. On Dec 18, 2014 this sequence version replaced NM_176888.1. ##Evidence-Data-START## Transcript is intronless :: BC101804.1, BC111998.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000390673.2/ ENSP00000375091.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGATGTGTT TTCTGCTCAT CATTTCATCA ATTCTGGTAG TGTTTGCATT TGTTCTTGGA 
AATGTTGCCA ATGGCTTCAT AGCCCTAGTA AATGTCATTG ACTGGGTTAA CACACGAAAG 
ATCTCCTCAG CTGAGCAAAT TCTCACTGCT CTGGTGGTCT CCAGAATTGG TTTACTCTGG 
GTCATGTTAT TCCTTTGGTA TGCAACTGTG TTTAATTCTG CTTTATATGG TTTAGAAGTA 
AGAATTGTTG CTTCTAATGC CTGGGCTGTA ACGAACCATT TCAGCATGTG GCTTGCTGCT 
AGCCTCAGCA TATTTTGTTT GCTCAAGATT GCCAATTTCT CCAACCTTAT TTCTCTCCAC 
CTAAAGAAGA GAATTAAGAG TGTTGTTCTG GTGATACTGT TGGGGCCCTT GGTATTTCTG 
ATTTGTAATC TTGCTGTGAT AACCATGGAT GAGAGAGTGT GGACAAAAGA ATATGAAGGA 
AATGTGACTT GGAAGATCAA ATTGAGGAAT GCAATACACC TTTCAAGCTT GACTGTAACT 
ACTCTAGCAA ACCTCATACC CTTTACTCTG AGCCTAATAT GTTTTCTGCT GTTAATCTGT 
TCTCTTTGTA AACATCTCAA GAAGATGCGG CTCCATAGCA AAGGATCTCA AGATCCCAGC 
ACCAAGGTCC ATATAAAAGC TTTGCAAACT GTGACCTCCT TCCTCATGTT ATTTGCCATT 
TACTTTCTGT GTATAATCAC ATCAACTTGG AATCTTAGGA CACAGCAGAG CAAACTTGTA 
CTCCTGCTTT GCCAAACTGT TGCAATCATG TATCCTTCAT TCCACTCATT CATCCTGATT 
ATGGGAAGTA GGAAGCTAAA ACAGACCTTT CTTTCAGTTT TGTGGCAGAT GACACGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_795369.1
CDS	50..949
Translation	MMCFLLIISSILVVFAFVLGNVANGFIALVNVIDWVNTRKISSAEQILTALVVSRIGLLWVMLFLWYATVFNSALYGLEVRIVASNAWAVTNHFSMWLAASLSIFCLLKIANFSNLISLHLKKRIKSVVLVILLGPLVFLICNLAVITMDERVWTKEYEGNVTWKIKLRNAIHLSSLTVTTLANLIPFTLSLICFLLLICSLCKHLKKMRLHSKGSQDPSTKVHIKALQTVTSFLMLFAIYFLCIITSTWNLRTQQSKLVLLLCQTVAIMYPSFHSFILIMGSRKLKQTFLSVLWQMTR

Target ORF information:

RefSeq Version	NM_176888.2
Organism	Homo sapiens(human)
Definition	Homo sapiens taste 2 receptor member 19 (TAS2R19), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_176888.2

ORF Insert Sequence:

ATGATGTGTT TTCTGCTCAT CATTTCATCA ATTCTGGTAG TGTTTGCATT TGTTCTTGGA 
AATGTTGCCA ATGGCTTCAT AGCCCTAGTA AATGTCATTG ACTGGGTTAA CACACGAAAG 
ATCTCCTCAG CTGAGCAAAT TCTCACTGCT CTGGTGGTCT CCAGAATTGG TTTACTCTGG 
GTCATGTTAT TCCTTTGGTA TGCAACTGTG TTTAATTCTG CTTTATATGG TTTAGAAGTA 
AGAATTGTTG CTTCTAATGC CTGGGCTGTA ACGAACCATT TCAGCATGTG GCTTGCTGCT 
AGCCTCAGCA TATTTTGTTT GCTCAAGATT GCCAATTTCT CCAACCTTAT TTCTCTCCAC 
CTAAAGAAGA GAATTAAGAG TGTTGTTCTG GTGATACTGT TGGGGCCCTT GGTATTTCTG 
ATTTGTAATC TTGCTGTGAT AACCATGGAT GAGAGAGTGT GGACAAAAGA ATATGAAGGA 
AATGTGACTT GGAAGATCAA ATTGAGGAAT GCAATACACC TTTCAAGCTT GACTGTAACT 
ACTCTAGCAA ACCTCATACC CTTTACTCTG AGCCTAATAT GTTTTCTGCT GTTAATCTGT 
TCTCTTTGTA AACATCTCAA GAAGATGCGG CTCCATAGCA AAGGATCTCA AGATCCCAGC 
ACCAAGGTCC ATATAAAAGC TTTGCAAACT GTGACCTCCT TCCTCATGTT ATTTGCCATT 
TACTTTCTGT GTATAATCAC ATCAACTTGG AATCTTAGGA CACAGCAGAG CAAACTTGTA 
CTCCTGCTTT GCCAAACTGT TGCAATCATG TATCCTTCAT TCCACTCATT CATCCTGATT 
ATGGGAAGTA GGAAGCTAAA ACAGACCTTT CTTTCAGTTT TGTGGCAGAT GACACGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The perception of quinine taste intensity is associated with common genetic variants in a bitter receptor cluster on chromosome 12.
Human molecular genetics19(21)4278-85(2010 Nov)
Reed DR,Zhu G,Breslin PA,Duke FF,Henders AK,Campbell MJ,Montgomery GW,Medland SE,Martin NG,Wright MJ

The molecular receptive ranges of human TAS2R bitter taste receptors.
Chemical senses35(2)157-70(2010 Feb)
Meyerhof W,Batram C,Kuhn C,Brockhoff A,Chudoba E,Bufe B,Appendino G,Behrens M

Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.
Genetics170(1)313-26(2005 May)
Go Y,Satta Y,Takenaka O,Takahata N

Evolution of bitter taste receptors in humans and apes.
Molecular biology and evolution22(3)432-6(2005 Mar)
Fischer A,Gilad Y,Man O,P??bo S

Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.
Cell112(3)293-301(2003 Feb)
Zhang Y,Hoon MA,Chandrashekar J,Mueller KL,Cook B,Wu D,Zuker CS,Ryba NJ