| Gene Symbol | POU2F3 |
| Entrez Gene ID | 25833 |
| Full Name | POU class 2 homeobox 3 |
| Synonyms | Epoc-1,OCT-11,OCT11,OTF-11,PLA-1,PLA1,Skn-1a |
| General protein information |
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| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]. |
| Disorder MIM: |








































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