EDC4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	EDC4
Entrez Gene ID	23644
Full Name	enhancer of mRNA decapping 4
Synonyms	GE1,Ge-1,HEDL5,HEDLS,RCD-8,RCD8
General protein information	Preferred Names enhancer of mRNA decapping 4 Names enhancer of mRNA-decapping protein 4 autoantigen Ge-1 autoantigen RCD-8 human enhancer of decapping large subunit
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16q22.1
Disorder MIM:	606030

mRNA and Protein(s)

mRNA	Protein	Name
NM_014329.4	NP_055144.3	enhancer of mRNA-decapping protein 4
NM_014329.5	NP_055144.3	enhancer of mRNA-decapping protein 4

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	edc4	XP_002935417.2
Pan troglodytes (chimpanzee)	EDC4	XP_003315200.1
Canis lupus familiaris (dog)	EDC4	XP_546871.3
Danio rerio (zebrafish)	edc4	NP_001038550.1
Bos taurus (cattle)	EDC4	XP_002694948.2
Mus musculus (house mouse)	Edc4	NP_853625.1
Gallus gallus (chicken)	EDC4	XP_414022.4
Homo sapiens (human)	EDC4	NP_055144.3
Rattus norvegicus (Norway rat)	Edc4	NP_001028240.3

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

A human microprotein that interacts with the mRNA decapping complex.
D'Lima NG, Ma J, Winkler L, Chu Q, Loh KH, Corpuz EO, Budnik BA, Lykke-Andersen J, Saghatelian A, Slavoff SA
Nature chemical biology13(2)174-180(2017 02)

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M
Cell163(3)712-23(2015 Oct)

The Assembly of EDC4 and Dcp1a into Processing Bodies Is Critical for the Translational Regulation of IL-6.
Seto E, Yoshida-Sugitani R, Kobayashi T, Toyama-Sorimachi N
PloS one10(5)e0123223(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The assembly of EDC4 and Dcp1a into processing bodies is critical for the translational regulation of IL-6.
Title: The Assembly of EDC4 and Dcp1a into Processing Bodies Is Critical for the Translational Regulation of IL-6.

EDC4 is a processing body (P-body) component.
Title: CCHCR1 interacts with EDC4, suggesting its localization in P-bodies.

The data indicates that DCP2 activation by DCP1 occurs preferentially on the EDC4 scaffold, which may serve to couple DCP2 activation by DCP1 with 5'-to-3' mRNA degradation by XRN1 in human cells.
Title: The activation of the decapping enzyme DCP2 by DCP1 occurs on the EDC4 scaffold and involves a conserved loop in DCP1.

LMKB is the first protein identified to date that interacts with this portion of Ge-1. LMKB was expressed in human B and T lymphocyte cell lines; depletion of LMKB increased expression of IFI44L.
Title: LMKB/MARF1 localizes to mRNA processing bodies, interacts with Ge-1, and regulates IFI44L gene expression.

EDC4 might contribute to regulation of CoA biosynthesis in addition to its scaffold function in processing bodies
Title: EDC4 interacts with and regulates the dephospho-CoA kinase activity of CoA synthase.

The following EDC4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the EDC4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu06313	NM_014329.5 Latest version!	Homo sapiens enhancer of mRNA decapping 4 (EDC4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$274.50-$384.30 $549.00
View Old Accession Versions >>
OHu06313	NM_014329.4	Homo sapiens enhancer of mRNA decapping 4 (EDC4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$274.50-$384.30 $549.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

EDC4 ( NM_014329.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055144.3 Homo sapiens enhancer of mRNA decapping 4 (EDC4), mRNA.

Price & Availability↑

CloneID	OHu06313
Clone ID Related Accession (Same CDS sequence)	NM_014329.4 , NM_014329.5
Accession Version	NM_014329.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4206bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	enhancer of mRNA-decapping protein 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC403765.1, BC064567.1 and AI631525.1. On Nov 5, 2011 this sequence version replaced NM_014329.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.133095.1, SRR1803617.183345.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCTCCT GCGCGAGCAT CGACATCGAG GACGCCACGC AGCACCTGCG GGACATCCTC 
AAGCTGGACC GGCCCGCGGG CGGCCCCAGT GCAGAGAGCC CACGGCCATC CAGTGCCTAC 
AATGGGGACC TCAATGGACT TCTGGTCCCA GACCCGCTCT GCTCAGGTGA TAGTACCTCA 
GCAAACAAGA CTGGTCTTCG GACCATGCCA CCCATTAACC TGCAAGAGAA GCAGGTCATC 
TGTCTCTCAG GAGATGATAG CTCCACCTGC ATTGGGATTT TGGCCAAGGA GGTGGAGATT 
GTGGCTAGCA GTGACTCTAG CATTTCAAGC AAGGCCCGGG GAAGCAACAA GGTGAAAATT 
CAGCCTGTCG CCAAGTATGA CTGGGAACAG AAGTACTACT ATGGCAACCT GATTGCTGTG 
TCTAACTCCT TCTTGGCCTA TGCCATTCGG GCTGCCAACA ATGGCTCTGC CATGGTGCGG 
GTGATCAGCG TCAGCACTTC GGAGCGGACC TTGCTCAAGG GCTTCACAGG CAGTGTGGCT 
GATCTGGCTT TCGCGCACCT CAACTCTCCA CAGCTGGCCT GCCTGGATGA GGCAGGCAAC 
CTGTTCGTGT GGCGCTTGGC TCTGGTTAAT GGCAAAATTC AAGAAGAGAT CTTGGTCCAT 
ATTCGGCAGC CAGAGGGCAC GCCACTGAAC CACTTTCGCA GGATCATCTG GTGCCCCTTC 
ATCCCTGAGG AGAGCGAAGA CTGCTGTGAG GAGAGCAGCC CAACAGTGGC CCTGCTGCAT 
GAAGACCGGG CTGAGGTGTG GGACCTGGAC ATGCTCCGCT CCAGCCACAG TACCTGGCCT 
GTGGATGTTA GCCAGATCAA GCAGGGCTTC ATTGTGGTAA AAGGTCATAG CACGTGCCTC 
AGTGAAGGAG CCCTCTCTCC TGATGGGACT GTGCTGGCTA CTGCGAGCCA CGATGGCTAT 
GTCAAGTTCT GGCAGATCTA CATTGAGGGG CAAGATGAGC CAAGGTGTCT GCACGAGTGG 
AAACCTCATG ATGGGCGGCC CCTCTCCTGC CTCCTGTTCT GTGACAACCA TAAGAAACAA 
GACCCTGATG TCCCTTTCTG GAGGTTCCTT ATTACTGGTG CTGACCAGAA CCGAGAGTTA 
AAGATGTGGT GTACAGTATC CTGGACCTGC CTGCAGACTA TTCGCTTCTC CCCAGATATC 
TTCAGCTCAG TGAGTGTGCC CCCTAGCCTC AAGGTTTGCT TGGACCTCTC AGCAGAATAC 
CTGATTCTCA GCGATGTGCA ACGGAAGGTC CTCTATGTGA TGGAGCTGCT GCAAAACCAG 
GAGGAGGGCC ACGCCTGCTT CAGCTCCATC TCGGAGTTCC TGCTCACCCA CCCTGTGCTG 
AGCTTTGGTA TCCAGGTTGT GAGTCGCTGC CGGCTACGGC ACACTGAGGT GCTGCCTGCC 
GAAGAGGAAA ATGACAGCCT GGGTGCTGAT GGTACCCATG GAGCCGGTGC CATGGAGTCT 
GCGGCCGGTG TGCTCATCAA GCTCTTTTGT GTGCATACTA AGGCACTGCA AGATGTGCAG 
ATCCGCTTCC AGCCACAGCT GAACCCTGAT GTGGTGGCCC CACTGCCCAC CCACACTGCC 
CACGAGGACT TCACATTTGG AGAGTCTCGG CCCGAACTGG GCTCTGAGGG CCTGGGGTCA 
GCCGCTCACG GCTCCCAGCC TGACCTCCGA CGAATCGTGG AGCTGCCTGC ACCTGCCGAC 
TTCCTCAGTC TGAGCAGTGA GACCAAGCCC AAGTTGATGA CACCTGACGC CTTCATGACA 
CCTAGCGCCT CCTTGCAGCA GATCACTGCC TCTCCCAGCA GCAGCAGCAG CGGTAGCAGC 
AGCAGCAGCA GCAGTAGCAG CAGCTCCCTT ACAGCTGTGT CTGCCATGAG CAGCACCTCA 
GCTGTGGACC CCTCCTTGAC CAGGCCACCT GAGGAGCTGA CCTTGAGCCC CAAGCTGCAG 
CTGGATGGCA GCCTGACAAT GAGCAGCAGT GGCAGCCTTC AGGCAAGCCC GCGTGGCCTC 
CTGCCTGGCC TGCTCCCAGC CCCAGCTGAC AAACTGACTC CCAAGGGGCC GGGCCAGGTG 
CCTACTGCCA CCTCTGCACT GTCCCTGGAG CTGCAGGAAG TGGAGCCCCT GGGGCTACCC 
CAAGCCTCCC CTAGCCGCAC TCGTTCCCCT GATGTCATCT CCTCAGCTTC CACTGCCCTG 
TCCCAGGACA TCCCTGAGAT TGCATCTGAG GCCCTGTCCC GTGGTTTTGG CTCCTCTGCA 
CCAGAGGGCC TTGAGCCAGA CAGTATGGCT TCAGCCGCCT CGGCACTGCA CCTGCTGTCC 
CCACGGCCCC GGCCAGGGCC CGAGCTCGGC CCCCAGCTCG GGCTTGATGG AGGCCCTGGG 
GATGGAGATC GGCATAATAC CCCCTCCCTC CTGGAGGCAG CCTTGACCCA GGAGGCCTCG 
ACTCCTGACA GTCAGGTTTG GCCCACAGCA CCTGACATTA CTCGTGAGAC CTGCAGCACC 
CTGGCAGAAA GCCCCAGGAA TGGCCTTCAG GAAAAGCACA AGAGCCTGGC CTTCCACCGA 
CCACCATATC ACCTGCTGCA GCAACGTGAC AGCCAGGATG CCAGTGCTGA GCAAAGTGAC 
CATGATGATG AGGTGGCCAG CCTTGCCTCT GCTTCAGGAG GCTTTGGCAC CAAAGTTCCT 
GCTCCACGGC TGCCTGCCAA GGACTGGAAG ACCAAGGGAT CCCCTCGAAC CTCACCCAAG 
CTCAAGAGGA AAAGCAAGAA GGATGATGGG GATGCAGCCA TGGGATCCCG GCTCACAGAG 
CACCAGGTGG CAGAGCCCCC TGAGGACTGG CCAGCACTAA TTTGGCAACA GCAGAGAGAG 
CTGGCAGAGC TGCGGCACAG CCAGGAAGAG CTGCTGCAGC GTCTGTGTAC CCAACTCGAA 
GGCCTGCAGA GCACAGTCAC AGGCCACGTA GAACGTGCCC TTGAGACTCG GCACGAGCAG 
GAACAGCGGC GGCTGGAGCG AGCACTGGCT GAGGGGCAGC AGCGGGGAGG GCAGCTGCAG 
GAGCAGCTGA CACAACAGTT GTCCCAAGCA CTGTCGTCAG CTGTAGCTGG GCGGCTAGAG 
CGCAGCATAC GGGATGAGAT CAAGAAGACA GTCCCTCCAT GTGTCTCAAG GAGTCTGGAG 
CCTATGGCAG GCCAACTGAG CAACTCAGTG GCTACCAAGC TCACAGCTGT GGAGGGCAGC 
ATGAAAGAGA ACATCTCCAA GCTGCTCAAG TCCAAGAACT TGACTGATGC CATCGCCCGA 
GCAGCTGCAG ACACATTACA AGGGCCGATG CAGGCTGCCT ACCGGGAAGC CTTCCAGAGT 
GTGGTGCTGC CGGCCTTTGA GAAGAGCTGC CAGGCCATGT TCCAGCAAAT CAATGATAGC 
TTCCGGCTGG GGACACAGGA ATACTTGCAG CAGCTAGAAA GCCACATGAA GAGCCGGAAG 
GCACGGGAAC AGGAGGCCAG GGAGCCTGTG CTAGCCCAGC TGCGGGGCCT GGTCAGCACA 
CTGCAGAGTG CCACTGAGCA GATGGCAGCC ACCGTGGCCG GCAGTGTTCG TGCTGAGGTG 
CAGCACCAGC TGCATGTGGC TGTGGGCAGC CTGCAGGAGT CCATTTTAGC ACAGGTACAG 
CGCATCGTTA AGGGTGAGGT GAGTGTGGCG CTCAAGGAGC AGCAGGCCGC CGTCACCTCC 
AGCATCATGC AGGCCATGCG CTCAGCTGCT GGCACACCTG TCCCCTCTGC CCACCTTGAC 
TGCCAGGCCC AGCAAGCCCA TATCCTGCAG CTGCTGCAGC AGGGCCACCT CAATCAGGCC 
TTCCAGCAGG CGCTGACAGC TGCTGACCTG AACCTGGTGC TGTATGTGTG TGAAACTGTG 
GACCCAGCCC AGGTTTTTGG GCAGCCACCC TGCCCGCTCT CCCAGCCTGT GCTCCTTTCC 
CTCATCCAGC AGCTGGCATC TGACCTTGGC ACTCGAACTG ACCTCAAGCT CAGCTACCTG 
GAAGAGGCCG TGATGCACCT GGACCACAGT GACCCCATCA CTCGGGACCA CATGGGCTCC 
GTTATGGCCC AGGTGCGCCA AAAGCTTTTT CAGTTCCTGC AGGCTGAGCC ACACAACTCA 
CTTGGCAAAG CAGCTCGGCG TCTCAGCCTC ATGCTGCATG GCCTCGTGAC CCCCAGCCTC 
CCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055144.3
CDS	240..4445
Translation	MASCASIDIEDATQHLRDILKLDRPAGGPSAESPRPSSAYNGDLNGLLVPDPLCSGDSTSANKTGLRTMPPINLQEKQVICLSGDDSSTCIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHLNSPQLACLDEAGNLFVWRLALVNGKIQEEILVHIRQPEGTPLNHFRRIIWCPFIPEESEDCCEESSPTVALLHEDRAEVWDLDMLRSSHSTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGYVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPDVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSSVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQEEGHACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEENDSLGADGTHGAGAMESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLPTHTAHEDFTFGESRPELGSEGLGSAAHGSQPDLRRIVELPAPADFLSLSSETKPKLMTPDAFMTPSASLQQITASPSSSSSGSSSSSSSSSSSLTAVSAMSSTSAVDPSLTRPPEELTLSPKLQLDGSLTMSSSGSLQASPRGLLPGLLPAPADKLTPKGPGQVPTATSALSLELQEVEPLGLPQASPSRTRSPDVISSASTALSQDIPEIASEALSRGFGSSAPEGLEPDSMASAASALHLLSPRPRPGPELGPQLGLDGGPGDGDRHNTPSLLEAALTQEASTPDSQVWPTAPDITRETCSTLAESPRNGLQEKHKSLAFHRPPYHLLQQRDSQDASAEQSDHDDEVASLASASGGFGTKVPAPRLPAKDWKTKGSPRTSPKLKRKSKKDDGDAAMGSRLTEHQVAEPPEDWPALIWQQQRELAELRHSQEELLQRLCTQLEGLQSTVTGHVERALETRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSIRDEIKKTVPPCVSRSLEPMAGQLSNSVATKLTAVEGSMKENISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLESHMKSRKAREQEAREPVLAQLRGLVSTLQSATEQMAATVAGSVRAEVQHQLHVAVGSLQESILAQVQRIVKGEVSVALKEQQAAVTSSIMQAMRSAAGTPVPSAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPAQVFGQPPCPLSQPVLLSLIQQLASDLGTRTDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQAEPHNSLGKAARRLSLMLHGLVTPSLP

Target ORF information:

RefSeq Version	NM_014329.4
Organism	Homo sapiens(human)
Definition	Homo sapiens enhancer of mRNA decapping 4 (EDC4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014329.4

ORF Insert Sequence:

ATGGCCTCCT GCGCGAGCAT CGACATCGAG GACGCCACGC AGCACCTGCG GGACATCCTC 
AAGCTGGACC GGCCCGCGGG CGGCCCCAGT GCAGAGAGCC CACGGCCATC CAGTGCCTAC 
AATGGGGACC TCAATGGACT TCTGGTCCCA GACCCGCTCT GCTCAGGTGA TAGTACCTCA 
GCAAACAAGA CTGGTCTTCG GACCATGCCA CCCATTAACC TGCAAGAGAA GCAGGTCATC 
TGTCTCTCAG GAGATGATAG CTCCACCTGC ATTGGGATTT TGGCCAAGGA GGTGGAGATT 
GTGGCTAGCA GTGACTCTAG CATTTCAAGC AAGGCCCGGG GAAGCAACAA GGTGAAAATT 
CAGCCTGTCG CCAAGTATGA CTGGGAACAG AAGTACTACT ATGGCAACCT GATTGCTGTG 
TCTAACTCCT TCTTGGCCTA TGCCATTCGG GCTGCCAACA ATGGCTCTGC CATGGTGCGG 
GTGATCAGCG TCAGCACTTC GGAGCGGACC TTGCTCAAGG GCTTCACAGG CAGTGTGGCT 
GATCTGGCTT TCGCGCACCT CAACTCTCCA CAGCTGGCCT GCCTGGATGA GGCAGGCAAC 
CTGTTCGTGT GGCGCTTGGC TCTGGTTAAT GGCAAAATTC AAGAAGAGAT CTTGGTCCAT 
ATTCGGCAGC CAGAGGGCAC GCCACTGAAC CACTTTCGCA GGATCATCTG GTGCCCCTTC 
ATCCCTGAGG AGAGCGAAGA CTGCTGTGAG GAGAGCAGCC CAACAGTGGC CCTGCTGCAT 
GAAGACCGGG CTGAGGTGTG GGACCTGGAC ATGCTCCGCT CCAGCCACAG TACCTGGCCT 
GTGGATGTTA GCCAGATCAA GCAGGGCTTC ATTGTGGTAA AAGGTCATAG CACGTGCCTC 
AGTGAAGGAG CCCTCTCTCC TGATGGGACT GTGCTGGCTA CTGCGAGCCA CGATGGCTAT 
GTCAAGTTCT GGCAGATCTA CATTGAGGGG CAAGATGAGC CAAGGTGTCT GCACGAGTGG 
AAACCTCATG ATGGGCGGCC CCTCTCCTGC CTCCTGTTCT GTGACAACCA TAAGAAACAA 
GACCCTGATG TCCCTTTCTG GAGGTTCCTT ATTACTGGTG CTGACCAGAA CCGAGAGTTA 
AAGATGTGGT GTACAGTATC CTGGACCTGC CTGCAGACTA TTCGCTTCTC CCCAGATATC 
TTCAGCTCAG TGAGTGTGCC CCCTAGCCTC AAGGTTTGCT TGGACCTCTC AGCAGAATAC 
CTGATTCTCA GCGATGTGCA ACGGAAGGTC CTCTATGTGA TGGAGCTGCT GCAAAACCAG 
GAGGAGGGCC ACGCCTGCTT CAGCTCCATC TCGGAGTTCC TGCTCACCCA CCCTGTGCTG 
AGCTTTGGTA TCCAGGTTGT GAGTCGCTGC CGGCTACGGC ACACTGAGGT GCTGCCTGCC 
GAAGAGGAAA ATGACAGCCT GGGTGCTGAT GGTACCCATG GAGCCGGTGC CATGGAGTCT 
GCGGCCGGTG TGCTCATCAA GCTCTTTTGT GTGCATACTA AGGCACTGCA AGATGTGCAG 
ATCCGCTTCC AGCCACAGCT GAACCCTGAT GTGGTGGCCC CACTGCCCAC CCACACTGCC 
CACGAGGACT TCACATTTGG AGAGTCTCGG CCCGAACTGG GCTCTGAGGG CCTGGGGTCA 
GCCGCTCACG GCTCCCAGCC TGACCTCCGA CGAATCGTGG AGCTGCCTGC ACCTGCCGAC 
TTCCTCAGTC TGAGCAGTGA GACCAAGCCC AAGTTGATGA CACCTGACGC CTTCATGACA 
CCTAGCGCCT CCTTGCAGCA GATCACTGCC TCTCCCAGCA GCAGCAGCAG CGGTAGCAGC 
AGCAGCAGCA GCAGTAGCAG CAGCTCCCTT ACAGCTGTGT CTGCCATGAG CAGCACCTCA 
GCTGTGGACC CCTCCTTGAC CAGGCCACCT GAGGAGCTGA CCTTGAGCCC CAAGCTGCAG 
CTGGATGGCA GCCTGACAAT GAGCAGCAGT GGCAGCCTTC AGGCAAGCCC GCGTGGCCTC 
CTGCCTGGCC TGCTCCCAGC CCCAGCTGAC AAACTGACTC CCAAGGGGCC GGGCCAGGTG 
CCTACTGCCA CCTCTGCACT GTCCCTGGAG CTGCAGGAAG TGGAGCCCCT GGGGCTACCC 
CAAGCCTCCC CTAGCCGCAC TCGTTCCCCT GATGTCATCT CCTCAGCTTC CACTGCCCTG 
TCCCAGGACA TCCCTGAGAT TGCATCTGAG GCCCTGTCCC GTGGTTTTGG CTCCTCTGCA 
CCAGAGGGCC TTGAGCCAGA CAGTATGGCT TCAGCCGCCT CGGCACTGCA CCTGCTGTCC 
CCACGGCCCC GGCCAGGGCC CGAGCTCGGC CCCCAGCTCG GGCTTGATGG AGGCCCTGGG 
GATGGAGATC GGCATAATAC CCCCTCCCTC CTGGAGGCAG CCTTGACCCA GGAGGCCTCG 
ACTCCTGACA GTCAGGTTTG GCCCACAGCA CCTGACATTA CTCGTGAGAC CTGCAGCACC 
CTGGCAGAAA GCCCCAGGAA TGGCCTTCAG GAAAAGCACA AGAGCCTGGC CTTCCACCGA 
CCACCATATC ACCTGCTGCA GCAACGTGAC AGCCAGGATG CCAGTGCTGA GCAAAGTGAC 
CATGATGATG AGGTGGCCAG CCTTGCCTCT GCTTCAGGAG GCTTTGGCAC CAAAGTTCCT 
GCTCCACGGC TGCCTGCCAA GGACTGGAAG ACCAAGGGAT CCCCTCGAAC CTCACCCAAG 
CTCAAGAGGA AAAGCAAGAA GGATGATGGG GATGCAGCCA TGGGATCCCG GCTCACAGAG 
CACCAGGTGG CAGAGCCCCC TGAGGACTGG CCAGCACTAA TTTGGCAACA GCAGAGAGAG 
CTGGCAGAGC TGCGGCACAG CCAGGAAGAG CTGCTGCAGC GTCTGTGTAC CCAACTCGAA 
GGCCTGCAGA GCACAGTCAC AGGCCACGTA GAACGTGCCC TTGAGACTCG GCACGAGCAG 
GAACAGCGGC GGCTGGAGCG AGCACTGGCT GAGGGGCAGC AGCGGGGAGG GCAGCTGCAG 
GAGCAGCTGA CACAACAGTT GTCCCAAGCA CTGTCGTCAG CTGTAGCTGG GCGGCTAGAG 
CGCAGCATAC GGGATGAGAT CAAGAAGACA GTCCCTCCAT GTGTCTCAAG GAGTCTGGAG 
CCTATGGCAG GCCAACTGAG CAACTCAGTG GCTACCAAGC TCACAGCTGT GGAGGGCAGC 
ATGAAAGAGA ACATCTCCAA GCTGCTCAAG TCCAAGAACT TGACTGATGC CATCGCCCGA 
GCAGCTGCAG ACACATTACA AGGGCCGATG CAGGCTGCCT ACCGGGAAGC CTTCCAGAGT 
GTGGTGCTGC CGGCCTTTGA GAAGAGCTGC CAGGCCATGT TCCAGCAAAT CAATGATAGC 
TTCCGGCTGG GGACACAGGA ATACTTGCAG CAGCTAGAAA GCCACATGAA GAGCCGGAAG 
GCACGGGAAC AGGAGGCCAG GGAGCCTGTG CTAGCCCAGC TGCGGGGCCT GGTCAGCACA 
CTGCAGAGTG CCACTGAGCA GATGGCAGCC ACCGTGGCCG GCAGTGTTCG TGCTGAGGTG 
CAGCACCAGC TGCATGTGGC TGTGGGCAGC CTGCAGGAGT CCATTTTAGC ACAGGTACAG 
CGCATCGTTA AGGGTGAGGT GAGTGTGGCG CTCAAGGAGC AGCAGGCCGC CGTCACCTCC 
AGCATCATGC AGGCCATGCG CTCAGCTGCT GGCACACCTG TCCCCTCTGC CCACCTTGAC 
TGCCAGGCCC AGCAAGCCCA TATCCTGCAG CTGCTGCAGC AGGGCCACCT CAATCAGGCC 
TTCCAGCAGG CGCTGACAGC TGCTGACCTG AACCTGGTGC TGTATGTGTG TGAAACTGTG 
GACCCAGCCC AGGTTTTTGG GCAGCCACCC TGCCCGCTCT CCCAGCCTGT GCTCCTTTCC 
CTCATCCAGC AGCTGGCATC TGACCTTGGC ACTCGAACTG ACCTCAAGCT CAGCTACCTG 
GAAGAGGCCG TGATGCACCT GGACCACAGT GACCCCATCA CTCGGGACCA CATGGGCTCC 
GTTATGGCCC AGGTGCGCCA AAAGCTTTTT CAGTTCCTGC AGGCTGAGCC ACACAACTCA 
CTTGGCAAAG CAGCTCGGCG TCTCAGCCTC ATGCTGCATG GCCTCGTGAC CCCCAGCCTC 
CCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

EDC4 ( NM_014329.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_055144.3 Homo sapiens enhancer of mRNA decapping 4 (EDC4), mRNA.

Price & Availability↑

CloneID	OHu06313
Clone ID Related Accession (Same CDS sequence)	NM_014329.4 , NM_014329.5
Accession Version	NM_014329.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4206bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	enhancer of mRNA-decapping protein 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC403765.1 and BC064567.1. On Nov 23, 2018 this sequence version replaced NM_014329.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC043616.1, SRR1803615.133095.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000358933.10/ ENSP00000351811.5 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCTCCT GCGCGAGCAT CGACATCGAG GACGCCACGC AGCACCTGCG GGACATCCTC 
AAGCTGGACC GGCCCGCGGG CGGCCCCAGT GCAGAGAGCC CACGGCCATC CAGTGCCTAC 
AATGGGGACC TCAATGGACT TCTGGTCCCA GACCCGCTCT GCTCAGGTGA TAGTACCTCA 
GCAAACAAGA CTGGTCTTCG GACCATGCCA CCCATTAACC TGCAAGAGAA GCAGGTCATC 
TGTCTCTCAG GAGATGATAG CTCCACCTGC ATTGGGATTT TGGCCAAGGA GGTGGAGATT 
GTGGCTAGCA GTGACTCTAG CATTTCAAGC AAGGCCCGGG GAAGCAACAA GGTGAAAATT 
CAGCCTGTCG CCAAGTATGA CTGGGAACAG AAGTACTACT ATGGCAACCT GATTGCTGTG 
TCTAACTCCT TCTTGGCCTA TGCCATTCGG GCTGCCAACA ATGGCTCTGC CATGGTGCGG 
GTGATCAGCG TCAGCACTTC GGAGCGGACC TTGCTCAAGG GCTTCACAGG CAGTGTGGCT 
GATCTGGCTT TCGCGCACCT CAACTCTCCA CAGCTGGCCT GCCTGGATGA GGCAGGCAAC 
CTGTTCGTGT GGCGCTTGGC TCTGGTTAAT GGCAAAATTC AAGAAGAGAT CTTGGTCCAT 
ATTCGGCAGC CAGAGGGCAC GCCACTGAAC CACTTTCGCA GGATCATCTG GTGCCCCTTC 
ATCCCTGAGG AGAGCGAAGA CTGCTGTGAG GAGAGCAGCC CAACAGTGGC CCTGCTGCAT 
GAAGACCGGG CTGAGGTGTG GGACCTGGAC ATGCTCCGCT CCAGCCACAG TACCTGGCCT 
GTGGATGTTA GCCAGATCAA GCAGGGCTTC ATTGTGGTAA AAGGTCATAG CACGTGCCTC 
AGTGAAGGAG CCCTCTCTCC TGATGGGACT GTGCTGGCTA CTGCGAGCCA CGATGGCTAT 
GTCAAGTTCT GGCAGATCTA CATTGAGGGG CAAGATGAGC CAAGGTGTCT GCACGAGTGG 
AAACCTCATG ATGGGCGGCC CCTCTCCTGC CTCCTGTTCT GTGACAACCA TAAGAAACAA 
GACCCTGATG TCCCTTTCTG GAGGTTCCTT ATTACTGGTG CTGACCAGAA CCGAGAGTTA 
AAGATGTGGT GTACAGTATC CTGGACCTGC CTGCAGACTA TTCGCTTCTC CCCAGATATC 
TTCAGCTCAG TGAGTGTGCC CCCTAGCCTC AAGGTTTGCT TGGACCTCTC AGCAGAATAC 
CTGATTCTCA GCGATGTGCA ACGGAAGGTC CTCTATGTGA TGGAGCTGCT GCAAAACCAG 
GAGGAGGGCC ACGCCTGCTT CAGCTCCATC TCGGAGTTCC TGCTCACCCA CCCTGTGCTG 
AGCTTTGGTA TCCAGGTTGT GAGTCGCTGC CGGCTACGGC ACACTGAGGT GCTGCCTGCC 
GAAGAGGAAA ATGACAGCCT GGGTGCTGAT GGTACCCATG GAGCCGGTGC CATGGAGTCT 
GCGGCCGGTG TGCTCATCAA GCTCTTTTGT GTGCATACTA AGGCACTGCA AGATGTGCAG 
ATCCGCTTCC AGCCACAGCT GAACCCTGAT GTGGTGGCCC CACTGCCCAC CCACACTGCC 
CACGAGGACT TCACATTTGG AGAGTCTCGG CCCGAACTGG GCTCTGAGGG CCTGGGGTCA 
GCCGCTCACG GCTCCCAGCC TGACCTCCGA CGAATCGTGG AGCTGCCTGC ACCTGCCGAC 
TTCCTCAGTC TGAGCAGTGA GACCAAGCCC AAGTTGATGA CACCTGACGC CTTCATGACA 
CCTAGCGCCT CCTTGCAGCA GATCACTGCC TCTCCCAGCA GCAGCAGCAG CGGTAGCAGC 
AGCAGCAGCA GCAGTAGCAG CAGCTCCCTT ACAGCTGTGT CTGCCATGAG CAGCACCTCA 
GCTGTGGACC CCTCCTTGAC CAGGCCACCT GAGGAGCTGA CCTTGAGCCC CAAGCTGCAG 
CTGGATGGCA GCCTGACAAT GAGCAGCAGT GGCAGCCTTC AGGCAAGCCC GCGTGGCCTC 
CTGCCTGGCC TGCTCCCAGC CCCAGCTGAC AAACTGACTC CCAAGGGGCC GGGCCAGGTG 
CCTACTGCCA CCTCTGCACT GTCCCTGGAG CTGCAGGAAG TGGAGCCCCT GGGGCTACCC 
CAAGCCTCCC CTAGCCGCAC TCGTTCCCCT GATGTCATCT CCTCAGCTTC CACTGCCCTG 
TCCCAGGACA TCCCTGAGAT TGCATCTGAG GCCCTGTCCC GTGGTTTTGG CTCCTCTGCA 
CCAGAGGGCC TTGAGCCAGA CAGTATGGCT TCAGCCGCCT CGGCACTGCA CCTGCTGTCC 
CCACGGCCCC GGCCAGGGCC CGAGCTCGGC CCCCAGCTCG GGCTTGATGG AGGCCCTGGG 
GATGGAGATC GGCATAATAC CCCCTCCCTC CTGGAGGCAG CCTTGACCCA GGAGGCCTCG 
ACTCCTGACA GTCAGGTTTG GCCCACAGCA CCTGACATTA CTCGTGAGAC CTGCAGCACC 
CTGGCAGAAA GCCCCAGGAA TGGCCTTCAG GAAAAGCACA AGAGCCTGGC CTTCCACCGA 
CCACCATATC ACCTGCTGCA GCAACGTGAC AGCCAGGATG CCAGTGCTGA GCAAAGTGAC 
CATGATGATG AGGTGGCCAG CCTTGCCTCT GCTTCAGGAG GCTTTGGCAC CAAAGTTCCT 
GCTCCACGGC TGCCTGCCAA GGACTGGAAG ACCAAGGGAT CCCCTCGAAC CTCACCCAAG 
CTCAAGAGGA AAAGCAAGAA GGATGATGGG GATGCAGCCA TGGGATCCCG GCTCACAGAG 
CACCAGGTGG CAGAGCCCCC TGAGGACTGG CCAGCACTAA TTTGGCAACA GCAGAGAGAG 
CTGGCAGAGC TGCGGCACAG CCAGGAAGAG CTGCTGCAGC GTCTGTGTAC CCAACTCGAA 
GGCCTGCAGA GCACAGTCAC AGGCCACGTA GAACGTGCCC TTGAGACTCG GCACGAGCAG 
GAACAGCGGC GGCTGGAGCG AGCACTGGCT GAGGGGCAGC AGCGGGGAGG GCAGCTGCAG 
GAGCAGCTGA CACAACAGTT GTCCCAAGCA CTGTCGTCAG CTGTAGCTGG GCGGCTAGAG 
CGCAGCATAC GGGATGAGAT CAAGAAGACA GTCCCTCCAT GTGTCTCAAG GAGTCTGGAG 
CCTATGGCAG GCCAACTGAG CAACTCAGTG GCTACCAAGC TCACAGCTGT GGAGGGCAGC 
ATGAAAGAGA ACATCTCCAA GCTGCTCAAG TCCAAGAACT TGACTGATGC CATCGCCCGA 
GCAGCTGCAG ACACATTACA AGGGCCGATG CAGGCTGCCT ACCGGGAAGC CTTCCAGAGT 
GTGGTGCTGC CGGCCTTTGA GAAGAGCTGC CAGGCCATGT TCCAGCAAAT CAATGATAGC 
TTCCGGCTGG GGACACAGGA ATACTTGCAG CAGCTAGAAA GCCACATGAA GAGCCGGAAG 
GCACGGGAAC AGGAGGCCAG GGAGCCTGTG CTAGCCCAGC TGCGGGGCCT GGTCAGCACA 
CTGCAGAGTG CCACTGAGCA GATGGCAGCC ACCGTGGCCG GCAGTGTTCG TGCTGAGGTG 
CAGCACCAGC TGCATGTGGC TGTGGGCAGC CTGCAGGAGT CCATTTTAGC ACAGGTACAG 
CGCATCGTTA AGGGTGAGGT GAGTGTGGCG CTCAAGGAGC AGCAGGCCGC CGTCACCTCC 
AGCATCATGC AGGCCATGCG CTCAGCTGCT GGCACACCTG TCCCCTCTGC CCACCTTGAC 
TGCCAGGCCC AGCAAGCCCA TATCCTGCAG CTGCTGCAGC AGGGCCACCT CAATCAGGCC 
TTCCAGCAGG CGCTGACAGC TGCTGACCTG AACCTGGTGC TGTATGTGTG TGAAACTGTG 
GACCCAGCCC AGGTTTTTGG GCAGCCACCC TGCCCGCTCT CCCAGCCTGT GCTCCTTTCC 
CTCATCCAGC AGCTGGCATC TGACCTTGGC ACTCGAACTG ACCTCAAGCT CAGCTACCTG 
GAAGAGGCCG TGATGCACCT GGACCACAGT GACCCCATCA CTCGGGACCA CATGGGCTCC 
GTTATGGCCC AGGTGCGCCA AAAGCTTTTT CAGTTCCTGC AGGCTGAGCC ACACAACTCA 
CTTGGCAAAG CAGCTCGGCG TCTCAGCCTC ATGCTGCATG GCCTCGTGAC CCCCAGCCTC 
CCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055144.3
CDS	211..4416
Translation	MASCASIDIEDATQHLRDILKLDRPAGGPSAESPRPSSAYNGDLNGLLVPDPLCSGDSTSANKTGLRTMPPINLQEKQVICLSGDDSSTCIGILAKEVEIVASSDSSISSKARGSNKVKIQPVAKYDWEQKYYYGNLIAVSNSFLAYAIRAANNGSAMVRVISVSTSERTLLKGFTGSVADLAFAHLNSPQLACLDEAGNLFVWRLALVNGKIQEEILVHIRQPEGTPLNHFRRIIWCPFIPEESEDCCEESSPTVALLHEDRAEVWDLDMLRSSHSTWPVDVSQIKQGFIVVKGHSTCLSEGALSPDGTVLATASHDGYVKFWQIYIEGQDEPRCLHEWKPHDGRPLSCLLFCDNHKKQDPDVPFWRFLITGADQNRELKMWCTVSWTCLQTIRFSPDIFSSVSVPPSLKVCLDLSAEYLILSDVQRKVLYVMELLQNQEEGHACFSSISEFLLTHPVLSFGIQVVSRCRLRHTEVLPAEEENDSLGADGTHGAGAMESAAGVLIKLFCVHTKALQDVQIRFQPQLNPDVVAPLPTHTAHEDFTFGESRPELGSEGLGSAAHGSQPDLRRIVELPAPADFLSLSSETKPKLMTPDAFMTPSASLQQITASPSSSSSGSSSSSSSSSSSLTAVSAMSSTSAVDPSLTRPPEELTLSPKLQLDGSLTMSSSGSLQASPRGLLPGLLPAPADKLTPKGPGQVPTATSALSLELQEVEPLGLPQASPSRTRSPDVISSASTALSQDIPEIASEALSRGFGSSAPEGLEPDSMASAASALHLLSPRPRPGPELGPQLGLDGGPGDGDRHNTPSLLEAALTQEASTPDSQVWPTAPDITRETCSTLAESPRNGLQEKHKSLAFHRPPYHLLQQRDSQDASAEQSDHDDEVASLASASGGFGTKVPAPRLPAKDWKTKGSPRTSPKLKRKSKKDDGDAAMGSRLTEHQVAEPPEDWPALIWQQQRELAELRHSQEELLQRLCTQLEGLQSTVTGHVERALETRHEQEQRRLERALAEGQQRGGQLQEQLTQQLSQALSSAVAGRLERSIRDEIKKTVPPCVSRSLEPMAGQLSNSVATKLTAVEGSMKENISKLLKSKNLTDAIARAAADTLQGPMQAAYREAFQSVVLPAFEKSCQAMFQQINDSFRLGTQEYLQQLESHMKSRKAREQEAREPVLAQLRGLVSTLQSATEQMAATVAGSVRAEVQHQLHVAVGSLQESILAQVQRIVKGEVSVALKEQQAAVTSSIMQAMRSAAGTPVPSAHLDCQAQQAHILQLLQQGHLNQAFQQALTAADLNLVLYVCETVDPAQVFGQPPCPLSQPVLLSLIQQLASDLGTRTDLKLSYLEEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQAEPHNSLGKAARRLSLMLHGLVTPSLP

Target ORF information:

RefSeq Version	NM_014329.5
Organism	Homo sapiens(human)
Definition	Homo sapiens enhancer of mRNA decapping 4 (EDC4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014329.5

ORF Insert Sequence:

ATGGCCTCCT GCGCGAGCAT CGACATCGAG GACGCCACGC AGCACCTGCG GGACATCCTC 
AAGCTGGACC GGCCCGCGGG CGGCCCCAGT GCAGAGAGCC CACGGCCATC CAGTGCCTAC 
AATGGGGACC TCAATGGACT TCTGGTCCCA GACCCGCTCT GCTCAGGTGA TAGTACCTCA 
GCAAACAAGA CTGGTCTTCG GACCATGCCA CCCATTAACC TGCAAGAGAA GCAGGTCATC 
TGTCTCTCAG GAGATGATAG CTCCACCTGC ATTGGGATTT TGGCCAAGGA GGTGGAGATT 
GTGGCTAGCA GTGACTCTAG CATTTCAAGC AAGGCCCGGG GAAGCAACAA GGTGAAAATT 
CAGCCTGTCG CCAAGTATGA CTGGGAACAG AAGTACTACT ATGGCAACCT GATTGCTGTG 
TCTAACTCCT TCTTGGCCTA TGCCATTCGG GCTGCCAACA ATGGCTCTGC CATGGTGCGG 
GTGATCAGCG TCAGCACTTC GGAGCGGACC TTGCTCAAGG GCTTCACAGG CAGTGTGGCT 
GATCTGGCTT TCGCGCACCT CAACTCTCCA CAGCTGGCCT GCCTGGATGA GGCAGGCAAC 
CTGTTCGTGT GGCGCTTGGC TCTGGTTAAT GGCAAAATTC AAGAAGAGAT CTTGGTCCAT 
ATTCGGCAGC CAGAGGGCAC GCCACTGAAC CACTTTCGCA GGATCATCTG GTGCCCCTTC 
ATCCCTGAGG AGAGCGAAGA CTGCTGTGAG GAGAGCAGCC CAACAGTGGC CCTGCTGCAT 
GAAGACCGGG CTGAGGTGTG GGACCTGGAC ATGCTCCGCT CCAGCCACAG TACCTGGCCT 
GTGGATGTTA GCCAGATCAA GCAGGGCTTC ATTGTGGTAA AAGGTCATAG CACGTGCCTC 
AGTGAAGGAG CCCTCTCTCC TGATGGGACT GTGCTGGCTA CTGCGAGCCA CGATGGCTAT 
GTCAAGTTCT GGCAGATCTA CATTGAGGGG CAAGATGAGC CAAGGTGTCT GCACGAGTGG 
AAACCTCATG ATGGGCGGCC CCTCTCCTGC CTCCTGTTCT GTGACAACCA TAAGAAACAA 
GACCCTGATG TCCCTTTCTG GAGGTTCCTT ATTACTGGTG CTGACCAGAA CCGAGAGTTA 
AAGATGTGGT GTACAGTATC CTGGACCTGC CTGCAGACTA TTCGCTTCTC CCCAGATATC 
TTCAGCTCAG TGAGTGTGCC CCCTAGCCTC AAGGTTTGCT TGGACCTCTC AGCAGAATAC 
CTGATTCTCA GCGATGTGCA ACGGAAGGTC CTCTATGTGA TGGAGCTGCT GCAAAACCAG 
GAGGAGGGCC ACGCCTGCTT CAGCTCCATC TCGGAGTTCC TGCTCACCCA CCCTGTGCTG 
AGCTTTGGTA TCCAGGTTGT GAGTCGCTGC CGGCTACGGC ACACTGAGGT GCTGCCTGCC 
GAAGAGGAAA ATGACAGCCT GGGTGCTGAT GGTACCCATG GAGCCGGTGC CATGGAGTCT 
GCGGCCGGTG TGCTCATCAA GCTCTTTTGT GTGCATACTA AGGCACTGCA AGATGTGCAG 
ATCCGCTTCC AGCCACAGCT GAACCCTGAT GTGGTGGCCC CACTGCCCAC CCACACTGCC 
CACGAGGACT TCACATTTGG AGAGTCTCGG CCCGAACTGG GCTCTGAGGG CCTGGGGTCA 
GCCGCTCACG GCTCCCAGCC TGACCTCCGA CGAATCGTGG AGCTGCCTGC ACCTGCCGAC 
TTCCTCAGTC TGAGCAGTGA GACCAAGCCC AAGTTGATGA CACCTGACGC CTTCATGACA 
CCTAGCGCCT CCTTGCAGCA GATCACTGCC TCTCCCAGCA GCAGCAGCAG CGGTAGCAGC 
AGCAGCAGCA GCAGTAGCAG CAGCTCCCTT ACAGCTGTGT CTGCCATGAG CAGCACCTCA 
GCTGTGGACC CCTCCTTGAC CAGGCCACCT GAGGAGCTGA CCTTGAGCCC CAAGCTGCAG 
CTGGATGGCA GCCTGACAAT GAGCAGCAGT GGCAGCCTTC AGGCAAGCCC GCGTGGCCTC 
CTGCCTGGCC TGCTCCCAGC CCCAGCTGAC AAACTGACTC CCAAGGGGCC GGGCCAGGTG 
CCTACTGCCA CCTCTGCACT GTCCCTGGAG CTGCAGGAAG TGGAGCCCCT GGGGCTACCC 
CAAGCCTCCC CTAGCCGCAC TCGTTCCCCT GATGTCATCT CCTCAGCTTC CACTGCCCTG 
TCCCAGGACA TCCCTGAGAT TGCATCTGAG GCCCTGTCCC GTGGTTTTGG CTCCTCTGCA 
CCAGAGGGCC TTGAGCCAGA CAGTATGGCT TCAGCCGCCT CGGCACTGCA CCTGCTGTCC 
CCACGGCCCC GGCCAGGGCC CGAGCTCGGC CCCCAGCTCG GGCTTGATGG AGGCCCTGGG 
GATGGAGATC GGCATAATAC CCCCTCCCTC CTGGAGGCAG CCTTGACCCA GGAGGCCTCG 
ACTCCTGACA GTCAGGTTTG GCCCACAGCA CCTGACATTA CTCGTGAGAC CTGCAGCACC 
CTGGCAGAAA GCCCCAGGAA TGGCCTTCAG GAAAAGCACA AGAGCCTGGC CTTCCACCGA 
CCACCATATC ACCTGCTGCA GCAACGTGAC AGCCAGGATG CCAGTGCTGA GCAAAGTGAC 
CATGATGATG AGGTGGCCAG CCTTGCCTCT GCTTCAGGAG GCTTTGGCAC CAAAGTTCCT 
GCTCCACGGC TGCCTGCCAA GGACTGGAAG ACCAAGGGAT CCCCTCGAAC CTCACCCAAG 
CTCAAGAGGA AAAGCAAGAA GGATGATGGG GATGCAGCCA TGGGATCCCG GCTCACAGAG 
CACCAGGTGG CAGAGCCCCC TGAGGACTGG CCAGCACTAA TTTGGCAACA GCAGAGAGAG 
CTGGCAGAGC TGCGGCACAG CCAGGAAGAG CTGCTGCAGC GTCTGTGTAC CCAACTCGAA 
GGCCTGCAGA GCACAGTCAC AGGCCACGTA GAACGTGCCC TTGAGACTCG GCACGAGCAG 
GAACAGCGGC GGCTGGAGCG AGCACTGGCT GAGGGGCAGC AGCGGGGAGG GCAGCTGCAG 
GAGCAGCTGA CACAACAGTT GTCCCAAGCA CTGTCGTCAG CTGTAGCTGG GCGGCTAGAG 
CGCAGCATAC GGGATGAGAT CAAGAAGACA GTCCCTCCAT GTGTCTCAAG GAGTCTGGAG 
CCTATGGCAG GCCAACTGAG CAACTCAGTG GCTACCAAGC TCACAGCTGT GGAGGGCAGC 
ATGAAAGAGA ACATCTCCAA GCTGCTCAAG TCCAAGAACT TGACTGATGC CATCGCCCGA 
GCAGCTGCAG ACACATTACA AGGGCCGATG CAGGCTGCCT ACCGGGAAGC CTTCCAGAGT 
GTGGTGCTGC CGGCCTTTGA GAAGAGCTGC CAGGCCATGT TCCAGCAAAT CAATGATAGC 
TTCCGGCTGG GGACACAGGA ATACTTGCAG CAGCTAGAAA GCCACATGAA GAGCCGGAAG 
GCACGGGAAC AGGAGGCCAG GGAGCCTGTG CTAGCCCAGC TGCGGGGCCT GGTCAGCACA 
CTGCAGAGTG CCACTGAGCA GATGGCAGCC ACCGTGGCCG GCAGTGTTCG TGCTGAGGTG 
CAGCACCAGC TGCATGTGGC TGTGGGCAGC CTGCAGGAGT CCATTTTAGC ACAGGTACAG 
CGCATCGTTA AGGGTGAGGT GAGTGTGGCG CTCAAGGAGC AGCAGGCCGC CGTCACCTCC 
AGCATCATGC AGGCCATGCG CTCAGCTGCT GGCACACCTG TCCCCTCTGC CCACCTTGAC 
TGCCAGGCCC AGCAAGCCCA TATCCTGCAG CTGCTGCAGC AGGGCCACCT CAATCAGGCC 
TTCCAGCAGG CGCTGACAGC TGCTGACCTG AACCTGGTGC TGTATGTGTG TGAAACTGTG 
GACCCAGCCC AGGTTTTTGG GCAGCCACCC TGCCCGCTCT CCCAGCCTGT GCTCCTTTCC 
CTCATCCAGC AGCTGGCATC TGACCTTGGC ACTCGAACTG ACCTCAAGCT CAGCTACCTG 
GAAGAGGCCG TGATGCACCT GGACCACAGT GACCCCATCA CTCGGGACCA CATGGGCTCC 
GTTATGGCCC AGGTGCGCCA AAAGCTTTTT CAGTTCCTGC AGGCTGAGCC ACACAACTCA 
CTTGGCAAAG CAGCTCGGCG TCTCAGCCTC ATGCTGCATG GCCTCGTGAC CCCCAGCCTC 
CCTTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

A human microprotein that interacts with the mRNA decapping complex.
Nature chemical biology13(2)174-180(2017 02)
D'Lima NG,Ma J,Winkler L,Chu Q,Loh KH,Corpuz EO,Budnik BA,Lykke-Andersen J,Saghatelian A,Slavoff SA

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Cell163(3)712-23(2015 Oct)
Hein MY,Hubner NC,Poser I,Cox J,Nagaraj N,Toyoda Y,Gak IA,Weisswange I,Mansfeld J,Buchholz F,Hyman AA,Mann M

The Assembly of EDC4 and Dcp1a into Processing Bodies Is Critical for the Translational Regulation of IL-6.
PloS one10(5)e0123223(2015)
Seto E,Yoshida-Sugitani R,Kobayashi T,Toyama-Sorimachi N

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EDC4 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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