SLC25A43 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SLC25A43
Entrez Gene ID	203427
Full Name	solute carrier family 25 member 43
General protein information	Preferred Names solute carrier family 25 member 43 Names solute carrier family 25 member 43
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq24
Summary	This gene encodes a member of the mitochondrial carrier family of proteins.[provided by RefSeq, Dec 2009].
Disorder MIM:	300641

mRNA and Protein(s)

mRNA	Protein	Name
NM_145305.3	NP_660348.2	solute carrier family 25 member 43
NM_145305.2	NP_660348.2	solute carrier family 25 member 43
XM_017029340.1	XP_016884829.1	solute carrier family 25 member 43 isoform X1
XM_017029341.1	XP_016884830.1	solute carrier family 25 member 43 isoform X2

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Slc25a43	XP_003752180.1
Gallus gallus (chicken)	SLC25A43	XP_420343.2
Homo sapiens (human)	SLC25A43	NP_660348.2
Mus musculus (house mouse)	Slc25a43	NP_001078966.1
Xenopus tropicalis (tropical clawed frog)	slc25a43	XP_002934585.1
Bos taurus (cattle)	SLC25A43	XP_002699515.1
Pan troglodytes (chimpanzee)	SLC25A43	XP_001136991.3
Canis lupus familiaris (dog)	SLC25A43	XP_538152.4
Danio rerio (zebrafish)	slc25a43	NP_001004497.2

Gene Ontology
Bibliography

Related articles in PubMed

Mitochondrial regulation of cell cycle progression through SLC25A43.
Gabrielson M, Reizer E, St?l O, Tina E
Biochemical and biophysical research communications469(4)1090-6(2016 Jan)

The mitochondrial transporter family SLC25: identification, properties and physiopathology.
Palmieri F
Molecular aspects of medicine34(2-3)465-84(2013 Apr-Jun)

The mitochondrial transport protein SLC25A43 affects drug efficacy and drug-induced cell cycle arrest in breast cancer cell lines.
Gabrielson M, Tina E
Oncology reports29(4)1268-74(2013 Apr)

The mitochondrial transporter SLC25A43 is frequently deleted and may influence cell proliferation in HER2-positive breast tumors.
Tina E, Lindqvist BM, Gabrielson M, Lubovac Z, Wegman P, Wingren S
BMC cancer12350(2012 Aug)

DNA methylation pattern of the SLC25A43 gene in breast cancer.
Lindqvist BM, Farkas SA, Wingren S, Nilsson TK
Epigenetics7(3)300-6(2012 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In line with our previous results, we show a role for SLC25A43 as a regulator of cell cycle progression and proliferation through a putative mitochondrial checkpoint.
Title: Mitochondrial regulation of cell cycle progression through SLC25A43.

Compares and contrasts all the known human SLC25A* genes and includes functional information.
Title: The mitochondrial transporter family SLC25: identification, properties and physiopathology.

Our findings demonstrate that the mitochondrial protein SLC25A43 affects drug efficacy and cell cycle regulation following drug exposure in breast cancer cell lines.
Title: The mitochondrial transport protein SLC25A43 affects drug efficacy and drug-induced cell cycle arrest in breast cancer cell lines.

Our results indicate a possible role of SLC25A43 in HER2-positive breast cancer and support the hypothesis of altered mitochondrial function in cancer.
Title: The mitochondrial transporter SLC25A43 is frequently deleted and may influence cell proliferation in HER2-positive breast tumors.

associations between site-specific methylation and clinicopathological parameters suggest that epigenetic changes in SLC25A43 gene could be of importance in breast carcinogenesis.
Title: DNA methylation pattern of the SLC25A43 gene in breast cancer.

The following SLC25A43 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC25A43 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu22138	NM_145305.3 Latest version!	Homo sapiens solute carrier family 25 member 43 (SLC25A43), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu99192	XM_017029340.1 Latest version!	Homo sapiens solute carrier family 25 member 43 (SLC25A43), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
OHu99193	XM_017029341.1 Latest version!	Homo sapiens solute carrier family 25 member 43 (SLC25A43), transcript variant X9, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu22138	NM_145305.2	Homo sapiens solute carrier family 25 member 43 (SLC25A43), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SLC25A43 ( NM_145305.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_660348.2 Homo sapiens solute carrier family 25 member 43 (SLC25A43), mRNA.

Price & Availability↑

CloneID	OHu22138
Clone ID Related Accession (Same CDS sequence)	NM_145305.3 , NM_145305.2
Accession Version	NM_145305.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1026bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	solute carrier family 25 member 43
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC004973.1, BC071871.1, AC004000.1 and BM907537.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_145305.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.385473.1, BC019584.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta MANE Ensembl match :: ENST00000217909.8/ ENSP00000217909.7 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCTACGT GGAGGCGGGA CGGCCGACTG ACAGGCGGCC AAAGGCTGCT GTGCGCTGGG 
CTGGCGGGGA CGCTCAGCCT CAGCCTCACC GCGCCCCTGG AGCTCGCCAC CGTGCTGGCC 
CAGGTTGGCG TCGTGCGAGG CCACGCCCGG GGACCGTGGG CCACAGGGCA CCGGGTGTGG 
CGGGCAGAGG GGCTCCGGGC CCTGTGGAAG GGGAACGCGG TGGCGTGCCT GCGCCTCTTC 
CCCTGCAGCG CCGTGCAGCT CGCCGCCTAC CGCAAATTTG TTGTGCTGTT CACAGATGAC 
CTGGGCCACA TTTCCCAGTG GAGCTCCATC ATGGCTGGGA GTCTCGCAGG CATGGTTTCC 
ACCATTGTAA CATATCCTAC AGACCTCATC AAAACCCGGT TGATCATGCA GAACATACTG 
GAACCATCGT ACAGGGGGCT CCTCCATGCT TTTTCTACTA TTTACCAACA GGAAGGGTTC 
CTTGCCCTTT ATCGAGGGGT TTCCCTCACT GTTGTAGGTG CTCTCCCGTT CTCTGCTGGC 
TCCCTTCTTG TTTACATGAA CCTGGAGAAA ATCTGGAACG GACCCCGAGA TCAGTTCTCT 
CTCCCACAGA ACTTTGCTAA TGTCTGTCTG GCTGCTGCAG TGACCCAGAC CCTCTCCTTT 
CCCTTTGAGA CCGTGAAGAG AAAGATGCAG GCTCAGAGCC CCTACCTCCC ACACAGTGGA 
GGAGTAGATG TCCATTTCTC AGGAGCAGTG GACTGCTTCC GGCAGATAGT GAAGGCCCAG 
GGGGTCCTGG GGCTCTGGAA TGGATTGACA GCCAATTTAC TGAAGATAGT TCCATATTTT 
GGAATTATGT TTAGCACCTT TGAGTTCTGC AAGAGAATCT GTCTTTATCA AAATGGTTAC 
ATTCTGTCTC CACTGAGCTA TAAATTGACC CCAGGAGTCG ATCAGAGTTT GCAGCCCCAG 
GAATTACGAG AATTAAAGAA GTTCTTCAAA ACGAGAAAAC CGAAGCCTAA AAAACCAACT 
CTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_660348.2
CDS	69..1094
Translation	MATWRRDGRLTGGQRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKRICLYQNGYILSPLSYKLTPGVDQSLQPQELRELKKFFKTRKPKPKKPTL

Target ORF information:

RefSeq Version	NM_145305.3
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 25 member 43 (SLC25A43), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145305.3

ORF Insert Sequence:

ATGGCTACGT GGAGGCGGGA CGGCCGACTG ACAGGCGGCC AAAGGCTGCT GTGCGCTGGG 
CTGGCGGGGA CGCTCAGCCT CAGCCTCACC GCGCCCCTGG AGCTCGCCAC CGTGCTGGCC 
CAGGTTGGCG TCGTGCGAGG CCACGCCCGG GGACCGTGGG CCACAGGGCA CCGGGTGTGG 
CGGGCAGAGG GGCTCCGGGC CCTGTGGAAG GGGAACGCGG TGGCGTGCCT GCGCCTCTTC 
CCCTGCAGCG CCGTGCAGCT CGCCGCCTAC CGCAAATTTG TTGTGCTGTT CACAGATGAC 
CTGGGCCACA TTTCCCAGTG GAGCTCCATC ATGGCTGGGA GTCTCGCAGG CATGGTTTCC 
ACCATTGTAA CATATCCTAC AGACCTCATC AAAACCCGGT TGATCATGCA GAACATACTG 
GAACCATCGT ACAGGGGGCT CCTCCATGCT TTTTCTACTA TTTACCAACA GGAAGGGTTC 
CTTGCCCTTT ATCGAGGGGT TTCCCTCACT GTTGTAGGTG CTCTCCCGTT CTCTGCTGGC 
TCCCTTCTTG TTTACATGAA CCTGGAGAAA ATCTGGAACG GACCCCGAGA TCAGTTCTCT 
CTCCCACAGA ACTTTGCTAA TGTCTGTCTG GCTGCTGCAG TGACCCAGAC CCTCTCCTTT 
CCCTTTGAGA CCGTGAAGAG AAAGATGCAG GCTCAGAGCC CCTACCTCCC ACACAGTGGA 
GGAGTAGATG TCCATTTCTC AGGAGCAGTG GACTGCTTCC GGCAGATAGT GAAGGCCCAG 
GGGGTCCTGG GGCTCTGGAA TGGATTGACA GCCAATTTAC TGAAGATAGT TCCATATTTT 
GGAATTATGT TTAGCACCTT TGAGTTCTGC AAGAGAATCT GTCTTTATCA AAATGGTTAC 
ATTCTGTCTC CACTGAGCTA TAAATTGACC CCAGGAGTCG ATCAGAGTTT GCAGCCCCAG 
GAATTACGAG AATTAAAGAA GTTCTTCAAA ACGAGAAAAC CGAAGCCTAA AAAACCAACT 
CTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC25A43 ( NM_145305.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_660348.2 Homo sapiens solute carrier family 25 member 43 (SLC25A43), mRNA.

Price & Availability↑

CloneID	OHu22138
Clone ID Related Accession (Same CDS sequence)	NM_145305.3 , NM_145305.2
Accession Version	NM_145305.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1026bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	solute carrier family 25 member 43
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC004973.1, BC071871.1, AC004000.1 and BM907537.1. This sequence is a reference standard in the RefSeqGene project. On Dec 29, 2009 this sequence version replaced NM_145305.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.385473.1, BC019584.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCTACGT GGAGGCGGGA CGGCCGACTG ACAGGCGGCC AAAGGCTGCT GTGCGCTGGG 
CTGGCGGGGA CGCTCAGCCT CAGCCTCACC GCGCCCCTGG AGCTCGCCAC CGTGCTGGCC 
CAGGTTGGCG TCGTGCGAGG CCACGCCCGG GGACCGTGGG CCACAGGGCA CCGGGTGTGG 
CGGGCAGAGG GGCTCCGGGC CCTGTGGAAG GGGAACGCGG TGGCGTGCCT GCGCCTCTTC 
CCCTGCAGCG CCGTGCAGCT CGCCGCCTAC CGCAAATTTG TTGTGCTGTT CACAGATGAC 
CTGGGCCACA TTTCCCAGTG GAGCTCCATC ATGGCTGGGA GTCTCGCAGG CATGGTTTCC 
ACCATTGTAA CATATCCTAC AGACCTCATC AAAACCCGGT TGATCATGCA GAACATACTG 
GAACCATCGT ACAGGGGGCT CCTCCATGCT TTTTCTACTA TTTACCAACA GGAAGGGTTC 
CTTGCCCTTT ATCGAGGGGT TTCCCTCACT GTTGTAGGTG CTCTCCCGTT CTCTGCTGGC 
TCCCTTCTTG TTTACATGAA CCTGGAGAAA ATCTGGAACG GACCCCGAGA TCAGTTCTCT 
CTCCCACAGA ACTTTGCTAA TGTCTGTCTG GCTGCTGCAG TGACCCAGAC CCTCTCCTTT 
CCCTTTGAGA CCGTGAAGAG AAAGATGCAG GCTCAGAGCC CCTACCTCCC ACACAGTGGA 
GGAGTAGATG TCCATTTCTC AGGAGCAGTG GACTGCTTCC GGCAGATAGT GAAGGCCCAG 
GGGGTCCTGG GGCTCTGGAA TGGATTGACA GCCAATTTAC TGAAGATAGT TCCATATTTT 
GGAATTATGT TTAGCACCTT TGAGTTCTGC AAGAGAATCT GTCTTTATCA AAATGGTTAC 
ATTCTGTCTC CACTGAGCTA TAAATTGACC CCAGGAGTCG ATCAGAGTTT GCAGCCCCAG 
GAATTACGAG AATTAAAGAA GTTCTTCAAA ACGAGAAAAC CGAAGCCTAA AAAACCAACT 
CTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_660348.2
CDS	110..1135
Translation	MATWRRDGRLTGGQRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKRICLYQNGYILSPLSYKLTPGVDQSLQPQELRELKKFFKTRKPKPKKPTL

Target ORF information:

RefSeq Version	NM_145305.2
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 25 member 43 (SLC25A43), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_145305.2

ORF Insert Sequence:

ATGGCTACGT GGAGGCGGGA CGGCCGACTG ACAGGCGGCC AAAGGCTGCT GTGCGCTGGG 
CTGGCGGGGA CGCTCAGCCT CAGCCTCACC GCGCCCCTGG AGCTCGCCAC CGTGCTGGCC 
CAGGTTGGCG TCGTGCGAGG CCACGCCCGG GGACCGTGGG CCACAGGGCA CCGGGTGTGG 
CGGGCAGAGG GGCTCCGGGC CCTGTGGAAG GGGAACGCGG TGGCGTGCCT GCGCCTCTTC 
CCCTGCAGCG CCGTGCAGCT CGCCGCCTAC CGCAAATTTG TTGTGCTGTT CACAGATGAC 
CTGGGCCACA TTTCCCAGTG GAGCTCCATC ATGGCTGGGA GTCTCGCAGG CATGGTTTCC 
ACCATTGTAA CATATCCTAC AGACCTCATC AAAACCCGGT TGATCATGCA GAACATACTG 
GAACCATCGT ACAGGGGGCT CCTCCATGCT TTTTCTACTA TTTACCAACA GGAAGGGTTC 
CTTGCCCTTT ATCGAGGGGT TTCCCTCACT GTTGTAGGTG CTCTCCCGTT CTCTGCTGGC 
TCCCTTCTTG TTTACATGAA CCTGGAGAAA ATCTGGAACG GACCCCGAGA TCAGTTCTCT 
CTCCCACAGA ACTTTGCTAA TGTCTGTCTG GCTGCTGCAG TGACCCAGAC CCTCTCCTTT 
CCCTTTGAGA CCGTGAAGAG AAAGATGCAG GCTCAGAGCC CCTACCTCCC ACACAGTGGA 
GGAGTAGATG TCCATTTCTC AGGAGCAGTG GACTGCTTCC GGCAGATAGT GAAGGCCCAG 
GGGGTCCTGG GGCTCTGGAA TGGATTGACA GCCAATTTAC TGAAGATAGT TCCATATTTT 
GGAATTATGT TTAGCACCTT TGAGTTCTGC AAGAGAATCT GTCTTTATCA AAATGGTTAC 
ATTCTGTCTC CACTGAGCTA TAAATTGACC CCAGGAGTCG ATCAGAGTTT GCAGCCCCAG 
GAATTACGAG AATTAAAGAA GTTCTTCAAA ACGAGAAAAC CGAAGCCTAA AAAACCAACT 
CTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC25A43 ( XM_017029340.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016884829.1 Homo sapiens solute carrier family 25 member 43 (SLC25A43), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu99192
Clone ID Related Accession (Same CDS sequence)	XM_017029340.1
Accession Version	XM_017029340.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	solute carrier family 25 member 43 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTACGT GGAGGCGGGA CGGCCGACTG ACAGGCGGCC AAAGGCTGCT GTGCGCTGGG 
CTGGCGGGGA CGCTCAGCCT CAGCCTCACC GCGCCCCTGG AGCTCGCCAC CGTGCTGGCC 
CAGGTTGGCG TCGTGCGAGG CCACGCCCGG GGACCGTGGG CCACAGGGCA CCGGGTGTGG 
CGGGCAGAGG GGCTCCGGGC CCTGTGGAAG GGGAACGCGG TGGCGTGCCT GCGCCTCTTC 
CCCTGCAGCG CCGTGCAGCT CGCCGCCTAC CGCAAATTTG TTGTGCTGTT CACAGATGAC 
CTGGGCCACA TTTCCCAGTG GAGCTCCATC ATGGCTGGGA GTCTCGCAGG CATGGTTTCC 
ACCATTGTAA CATATCCTAC AGACCTCATC AAAACCCGGT TGATCATGCA GAACATACTG 
GAACCATCGT ACAGGGGGCT CCTCCATGCT TTTTCTACTA TTTACCAACA GGAAGGGTTC 
CTTGCCCTTT ATCGAGGGGT TTCCCTCACT GTTGTAGGTG CTCTCCCGTT CTCTGCTGGC 
TCCCTTCTTG TTTACATGAA CCTGGAGAAA ATCTGGAACG GACCCCGAGA TCAGTTCTCT 
CTCCCACAGA ACTTTGCTAA TGTCTGTCTG GCTGCTGCAG TGACCCAGAC CCTCTCCTTT 
CCCTTTGAGA CCGTGAAGAG AAAGATGCAG AACAGTGACC TCATCTGGGA GAATCCAGCC 
AACACCGCAT TCTACACCAT CTGCATTCTA TACCCCTACC ACAACAACCC ACTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016884829.1
CDS	79..855
Translation	MATWRRDGRLTGGQRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQNSDLIWENPANTAFYTICILYPYHNNPL

Target ORF information:

RefSeq Version	XM_017029340.1
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 25 member 43 (SLC25A43), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029340.1

ORF Insert Sequence:

ATGGCTACGT GGAGGCGGGA CGGCCGACTG ACAGGCGGCC AAAGGCTGCT GTGCGCTGGG 
CTGGCGGGGA CGCTCAGCCT CAGCCTCACC GCGCCCCTGG AGCTCGCCAC CGTGCTGGCC 
CAGGTTGGCG TCGTGCGAGG CCACGCCCGG GGACCGTGGG CCACAGGGCA CCGGGTGTGG 
CGGGCAGAGG GGCTCCGGGC CCTGTGGAAG GGGAACGCGG TGGCGTGCCT GCGCCTCTTC 
CCCTGCAGCG CCGTGCAGCT CGCCGCCTAC CGCAAATTTG TTGTGCTGTT CACAGATGAC 
CTGGGCCACA TTTCCCAGTG GAGCTCCATC ATGGCTGGGA GTCTCGCAGG CATGGTTTCC 
ACCATTGTAA CATATCCTAC AGACCTCATC AAAACCCGGT TGATCATGCA GAACATACTG 
GAACCATCGT ACAGGGGGCT CCTCCATGCT TTTTCTACTA TTTACCAACA GGAAGGGTTC 
CTTGCCCTTT ATCGAGGGGT TTCCCTCACT GTTGTAGGTG CTCTCCCGTT CTCTGCTGGC 
TCCCTTCTTG TTTACATGAA CCTGGAGAAA ATCTGGAACG GACCCCGAGA TCAGTTCTCT 
CTCCCACAGA ACTTTGCTAA TGTCTGTCTG GCTGCTGCAG TGACCCAGAC CCTCTCCTTT 
CCCTTTGAGA CCGTGAAGAG AAAGATGCAG AACAGTGACC TCATCTGGGA GAATCCAGCC 
AACACCGCAT TCTACACCAT CTGCATTCTA TACCCCTACC ACAACAACCC ACTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC25A43 ( XM_017029341.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016884830.1 Homo sapiens solute carrier family 25 member 43 (SLC25A43), transcript variant X9, mRNA.

Price & Availability↑

CloneID	OHu99193
Clone ID Related Accession (Same CDS sequence)	XM_017029341.1
Accession Version	XM_017029341.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 696bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	solute carrier family 25 member 43 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTACGT GGAGGCGGGA CGGCCGACTG ACAGGCGGCC AAAGGCTGCT GTGCGCTGGG 
CTGGCGGGGA CGCTCAGCCT CAGCCTCACC GCGCCCCTGG AGCTCGCCAC CGTGCTGGCC 
CAGGTTGGCG TCGTGCGAGG CCACGCCCGG GGACCGTGGG CCACAGGGCA CCGGGTGTGG 
CGGGCAGAGG GGCTCCGGGC CCTGTGGAAG GGGAACGCGG TGGCGTGCCT GCGCCTCTTC 
CCCTGCAGCG CCGTGCAGCT CGCCGCCTAC CGCAAATTTG TTGTGCTGTT CACAGATGAC 
CTGGGCCACA TTTCCCAGTG GAGCTCCATC ATGGCTGGGA GTCTCGCAGG CATGGTTTCC 
ACCATTGTAA CATATCCTAC AGACCTCATC AAAACCCGGT TGATCATGCA GAACATACTG 
GAACCATCGT ACAGGGGGCT CCTCCATGCT TTTTCTACTA TTTACCAACA GGAAGGGTTC 
CTTGCCCTTT ATCGAGGGGT TTCCCTCACT GTTGTAGGTG CTCTCCCGTT CTCTGCTGGC 
TCCCTTCTTG TTTACATGAA CCTGGAGAAA ATCTGGAACG GACCCCGAGA TCAGTTCTCT 
CTCCCACAGA ACTTTGCTAA TGTCTGTCTG GCTGCTGCAG TGACCCAGAC CCTCTCCTTT 
CCCTTTGAGA CCGTGAAGAG AAAGATGCAG AGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016884830.1
CDS	79..774
Translation	MATWRRDGRLTGGQRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQS

Target ORF information:

RefSeq Version	XM_017029341.1
Organism	Homo sapiens(human)
Definition	Homo sapiens solute carrier family 25 member 43 (SLC25A43), transcript variant X9, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017029341.1

ORF Insert Sequence:

ATGGCTACGT GGAGGCGGGA CGGCCGACTG ACAGGCGGCC AAAGGCTGCT GTGCGCTGGG 
CTGGCGGGGA CGCTCAGCCT CAGCCTCACC GCGCCCCTGG AGCTCGCCAC CGTGCTGGCC 
CAGGTTGGCG TCGTGCGAGG CCACGCCCGG GGACCGTGGG CCACAGGGCA CCGGGTGTGG 
CGGGCAGAGG GGCTCCGGGC CCTGTGGAAG GGGAACGCGG TGGCGTGCCT GCGCCTCTTC 
CCCTGCAGCG CCGTGCAGCT CGCCGCCTAC CGCAAATTTG TTGTGCTGTT CACAGATGAC 
CTGGGCCACA TTTCCCAGTG GAGCTCCATC ATGGCTGGGA GTCTCGCAGG CATGGTTTCC 
ACCATTGTAA CATATCCTAC AGACCTCATC AAAACCCGGT TGATCATGCA GAACATACTG 
GAACCATCGT ACAGGGGGCT CCTCCATGCT TTTTCTACTA TTTACCAACA GGAAGGGTTC 
CTTGCCCTTT ATCGAGGGGT TTCCCTCACT GTTGTAGGTG CTCTCCCGTT CTCTGCTGGC 
TCCCTTCTTG TTTACATGAA CCTGGAGAAA ATCTGGAACG GACCCCGAGA TCAGTTCTCT 
CTCCCACAGA ACTTTGCTAA TGTCTGTCTG GCTGCTGCAG TGACCCAGAC CCTCTCCTTT 
CCCTTTGAGA CCGTGAAGAG AAAGATGCAG AGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Mitochondrial regulation of cell cycle progression through SLC25A43.
Biochemical and biophysical research communications469(4)1090-6(2016 Jan)
Gabrielson M,Reizer E,St?l O,Tina E

The mitochondrial transporter family SLC25: identification, properties and physiopathology.
Molecular aspects of medicine34(2-3)465-84(2013 Apr-Jun)
Palmieri F

The mitochondrial transport protein SLC25A43 affects drug efficacy and drug-induced cell cycle arrest in breast cancer cell lines.
Oncology reports29(4)1268-74(2013 Apr)
Gabrielson M,Tina E

The mitochondrial transporter SLC25A43 is frequently deleted and may influence cell proliferation in HER2-positive breast tumors.
BMC cancer12350(2012 Aug)
Tina E,Lindqvist BM,Gabrielson M,Lubovac Z,Wegman P,Wingren S

DNA methylation pattern of the SLC25A43 gene in breast cancer.
Epigenetics7(3)300-6(2012 Mar)
Lindqvist BM,Farkas SA,Wingren S,Nilsson TK