ELK4 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ELK4
Entrez Gene ID	2005
Full Name	ELK4, ETS transcription factor
Synonyms	SAP1
General protein information	Preferred Names ELK4, ETS transcription factor Names ETS domain-containing protein Elk-4 ELK4, ETS-domain protein (SRF accessory protein 1) SAP-1 serum response factor accessory protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q32.1
Summary	This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is phosphorylated by the kinases, MAPK1 and MAPK8. Several transcript variants have been described for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	600246

mRNA and Protein(s)

mRNA	Protein	Name
XM_005244951.4	XP_005245008.1	ETS domain-containing protein Elk-4 isoform X1
XM_017000580.1	XP_016856069.1	ETS domain-containing protein Elk-4 isoform X2
NM_001973.4	NP_001964.2	ETS domain-containing protein Elk-4 isoform a
NM_021795.2	NP_068567.1	ETS domain-containing protein Elk-4 isoform b
NM_001973.3	NP_001964.2	ETS domain-containing protein Elk-4 isoform a
XM_005244950.4	XP_005245007.1	ETS domain-containing protein Elk-4 isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ELK4	NP_001075081.1
Xenopus tropicalis (tropical clawed frog)	elk4	XP_002933036.1
Mus musculus (house mouse)	Elk4	NP_031949.2
Gallus gallus (chicken)	ELK4	XP_417965.2
Homo sapiens (human)	ELK4	NP_001964.2
Pan troglodytes (chimpanzee)	ELK4	XP_001145430.2
Canis lupus familiaris (dog)	ELK4	XP_545691.4
Rattus norvegicus (Norway rat)	Elk4	NP_001100643.1
	ELK4	XP_001087748.2
Danio rerio (zebrafish)	elk4	NP_571005.1

Gene Ontology
Bibliography

Related articles in PubMed

Ubiquitin-specific peptidase 7 (USP7)-mediated deubiquitination of the histone deacetylase SIRT7 regulates gluconeogenesis.
Jiang L, Xiong J, Zhan J, Yuan F, Tang M, Zhang C, Cao Z, Chen Y, Lu X, Li Y, Wang H, Wang L, Wang J, Zhu WG, Wang H
The Journal of biological chemistry292(32)13296-13311(2017 08)

Cyclin-dependent kinase 2 (CDK2) is a key mediator for EGF-induced cell transformation mediated through the ELK4/c-Fos signaling pathway.
Peng C, Zeng W, Su J, Kuang Y, He Y, Zhao S, Zhang J, Ma W, Bode AM, Dong Z, Chen X
Oncogene35(9)1170-9(2016 Mar)

Role of CTCF in Regulating SLC45A3-ELK4 Chimeric RNA.
Qin F, Song Y, Zhang Y, Facemire L, Frierson H, Li H
PloS one11(3)e0150382(2016)

SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation.
Barber MF, Michishita-Kioi E, Xi Y, Tasselli L, Kioi M, Moqtaderi Z, Tennen RI, Paredes S, Young NL, Chen K, Struhl K, Garcia BA, Gozani O, Li W, Chua KF
Nature487(7405)114-8(2012 Jul)

Chimeric transcript generated by cis-splicing of adjacent genes regulates prostate cancer cell proliferation.
Zhang Y, Gong M, Yuan H, Park HG, Frierson HF, Li H
Cancer discovery2(7)598-607(2012 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest that SIRT7 undergoes Lys-63 polyubiquitination, later removed by USP7 to repress enzymatic activity of SIRT7; USP7 and SIRT7 regulate gluconeogenesis via expression of glucose-6-phosphatase catalytic subunit (G6PC); SIRT7 targets G6PC promoter through ELK4. (SIRT7 = sirtuin 7; USP7 = ubiquitin specific peptidase 7; G6PC = glucose-6-phosphatase catalytic subunit; ELK4 = transcription factor ELK4)
Title: Ubiquitin-specific peptidase 7 (USP7)-mediated deubiquitination of the histone deacetylase SIRT7 regulates gluconeogenesis.

ELK4 is overexpressed in melanoma and knocking down the ELK4 or CDK2 expression significantly attenuated the malignant phenotype of melanoma cells
Title: Cyclin-dependent kinase 2 (CDK2) is a key mediator for EGF-induced cell transformation mediated through the ELK4/c-Fos signaling pathway.

CTCF has a role in regulating SLC45A3-ELK4 Chimeric RNA
Title: Role of CTCF in Regulating SLC45A3-ELK4 Chimeric RNA.

Data suggest that chimeric SLC45A3-ELK4 controls prostate cancer cell proliferation, and the chimera level correlates with prostate cancer disease progression.
Title: Chimeric transcript generated by cis-splicing of adjacent genes regulates prostate cancer cell proliferation.

SLC45A3-ELK4 may represent the first description of a recurrent RNA chimaeric transcript specific to prostate cancer that does not have a detectable DNA aberration
Title: Transcriptome sequencing to detect gene fusions in cancer.

The following ELK4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ELK4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29785	NM_021795.2 Latest version!	Homo sapiens ETS transcription factor ELK4 (ELK4), transcript variant b, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu21721	XM_005244950.4 Latest version!	Homo sapiens ELK4, ETS transcription factor (ELK4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu21721	XM_005244951.4 Latest version!	Homo sapiens ELK4, ETS transcription factor (ELK4), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu21721	NM_001973.4 Latest version!	Homo sapiens ETS transcription factor ELK4 (ELK4), transcript variant a, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu83299	XM_017000580.1 Latest version!	Homo sapiens ELK4, ETS transcription factor (ELK4), transcript variant X8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu21721	NM_001973.3	Homo sapiens ETS transcription factor ELK4 (ELK4), transcript variant a, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ELK4 ( NM_021795.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_068567.1 Homo sapiens ETS transcription factor ELK4 (ELK4), transcript variant b, mRNA.

Price & Availability↑

CloneID	OHu29785
Clone ID Related Accession (Same CDS sequence)	NM_021795.2
Accession Version	NM_021795.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1218bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-24
Organism	Homo sapiens(human)
Product	ETS domain-containing protein Elk-4 isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AI002107.1, AI005122.1, BE675475.1, BF433322.1, BE676052.1, BC040145.1, M85164.1, BX346360.1 and T27937.1. On or before Jun 1, 2011 this sequence version replaced XR_111967.1, XR_108340.1, XR_114975.1, NM_021795.1. Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region which results in a frameshift compared to variant 1. This results in a shorter protein (isoform b) which has a shorter and distinct C-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M85164.1, SRR1163655.193440.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01820695 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGACAGTG CTATCACCCT GTGGCAGTTC CTTCTTCAGC TCCTGCAGAA GCCTCAGAAC 
AAGCACATGA TCTGTTGGAC CTCTAATGAT GGGCAGTTTA AGCTTTTGCA GGCAGAAGAG 
GTGGCTCGTC TCTGGGGGAT TCGCAAGAAC AAGCCTAACA TGAATTATGA CAAACTCAGC 
CGAGCCCTCA GATACTATTA TGTAAAGAAT ATCATCAAAA AAGTGAATGG TCAGAAGTTT 
GTGTACAAGT TTGTCTCTTA TCCAGAGATT TTGAACATGG ATCCAATGAC AGTGGGCAGG 
ATTGAGGGTG ACTGTGAAAG TTTAAACTTC AGTGAAGTCA GCAGCAGTTC CAAAGATGTG 
GAGAATGGAG GGAAAGATAA ACCACCTCAG CCTGGTGCCA AGACCTCTAG CCGCAATGAC 
TACATACACT CTGGCTTATA TTCTTCATTT ACTCTCAACT CTTTGAACTC CTCCAATGTA 
AAGCTTTTCA AATTGATAAA GACTGAGAAT CCAGCCGAGA AACTGGCAGA GAAAAAATCT 
CCTCAGGAGC CCACACCATC TGTCATCAAA TTTGTCACGA CACCTTCCAA AAAGCCACCG 
GTTGAACCTG TTGCTGCCAC CATTTCAATT GGCCCAAGTA TTTCTCCATC TTCAGAAGAA 
ACTATCCAAG CTTTGGAGAC ATTGGTTTCC CCAAAACTGC CTTCCCTGGA AGCCCCAACC 
TCTGCCTCTA ACGTAATGAC TGCTTTTGCC ACCACACCAC CCATTTCGTC CATACCCCCT 
TTGCAGGAAC CTCCCAGAAC ACCTTCACCA CCACTGAGTT CTCACCCAGA CATCGACACA 
GACATTGATT CAGTGGCTTC TCAGCCAATG GAACTTCCAG AGAATTTGTC ACTGGAGCCT 
AAAGACCAGG ATTCAGTCTT GCTAGAAAAG GACAAAGTAA ATAATTCATC AAGATCCAAG 
AAACCCAAAG GGTTAGAACT GGCACCCACC CTTGTGATCA CGAGCAGTGA TCCAAGCCCA 
CTGGGAATAC TGAGCCCATC TCTCCCTACA GCTTCTCTTA CACCAGCATT TTTTTCACAG 
GTAGCTTGCT CGCTCTTTAT GGTGTCACCA TTGCTTTCAT TTATTTGCCC TTTTAAGCAA 
ATCCAGAATT TATACACTCA AGTTTGCTTT CTGTTACTTA GGTTTGTCTT AGAAAGGTTA 
TGTGTGACTG TCATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_068567.1
CDS	1251..2468
Translation	MDSAITLWQFLLQLLQKPQNKHMICWTSNDGQFKLLQAEEVARLWGIRKNKPNMNYDKLSRALRYYYVKNIIKKVNGQKFVYKFVSYPEILNMDPMTVGRIEGDCESLNFSEVSSSSKDVENGGKDKPPQPGAKTSSRNDYIHSGLYSSFTLNSLNSSNVKLFKLIKTENPAEKLAEKKSPQEPTPSVIKFVTTPSKKPPVEPVAATISIGPSISPSSEETIQALETLVSPKLPSLEAPTSASNVMTAFATTPPISSIPPLQEPPRTPSPPLSSHPDIDTDIDSVASQPMELPENLSLEPKDQDSVLLEKDKVNNSSRSKKPKGLELAPTLVITSSDPSPLGILSPSLPTASLTPAFFSQVACSLFMVSPLLSFICPFKQIQNLYTQVCFLLLRFVLERLCVTVM

Target ORF information:

RefSeq Version	NM_021795.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ETS transcription factor ELK4 (ELK4), transcript variant b, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_021795.2

ORF Insert Sequence:

ATGGACAGTG CTATCACCCT GTGGCAGTTC CTTCTTCAGC TCCTGCAGAA GCCTCAGAAC 
AAGCACATGA TCTGTTGGAC CTCTAATGAT GGGCAGTTTA AGCTTTTGCA GGCAGAAGAG 
GTGGCTCGTC TCTGGGGGAT TCGCAAGAAC AAGCCTAACA TGAATTATGA CAAACTCAGC 
CGAGCCCTCA GATACTATTA TGTAAAGAAT ATCATCAAAA AAGTGAATGG TCAGAAGTTT 
GTGTACAAGT TTGTCTCTTA TCCAGAGATT TTGAACATGG ATCCAATGAC AGTGGGCAGG 
ATTGAGGGTG ACTGTGAAAG TTTAAACTTC AGTGAAGTCA GCAGCAGTTC CAAAGATGTG 
GAGAATGGAG GGAAAGATAA ACCACCTCAG CCTGGTGCCA AGACCTCTAG CCGCAATGAC 
TACATACACT CTGGCTTATA TTCTTCATTT ACTCTCAACT CTTTGAACTC CTCCAATGTA 
AAGCTTTTCA AATTGATAAA GACTGAGAAT CCAGCCGAGA AACTGGCAGA GAAAAAATCT 
CCTCAGGAGC CCACACCATC TGTCATCAAA TTTGTCACGA CACCTTCCAA AAAGCCACCG 
GTTGAACCTG TTGCTGCCAC CATTTCAATT GGCCCAAGTA TTTCTCCATC TTCAGAAGAA 
ACTATCCAAG CTTTGGAGAC ATTGGTTTCC CCAAAACTGC CTTCCCTGGA AGCCCCAACC 
TCTGCCTCTA ACGTAATGAC TGCTTTTGCC ACCACACCAC CCATTTCGTC CATACCCCCT 
TTGCAGGAAC CTCCCAGAAC ACCTTCACCA CCACTGAGTT CTCACCCAGA CATCGACACA 
GACATTGATT CAGTGGCTTC TCAGCCAATG GAACTTCCAG AGAATTTGTC ACTGGAGCCT 
AAAGACCAGG ATTCAGTCTT GCTAGAAAAG GACAAAGTAA ATAATTCATC AAGATCCAAG 
AAACCCAAAG GGTTAGAACT GGCACCCACC CTTGTGATCA CGAGCAGTGA TCCAAGCCCA 
CTGGGAATAC TGAGCCCATC TCTCCCTACA GCTTCTCTTA CACCAGCATT TTTTTCACAG 
GTAGCTTGCT CGCTCTTTAT GGTGTCACCA TTGCTTTCAT TTATTTGCCC TTTTAAGCAA 
ATCCAGAATT TATACACTCA AGTTTGCTTT CTGTTACTTA GGTTTGTCTT AGAAAGGTTA 
TGTGTGACTG TCATGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ELK4 ( NM_001973.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001964.2 Homo sapiens ETS transcription factor ELK4 (ELK4), transcript variant a, mRNA.

Price & Availability↑

CloneID	OHu21721
Clone ID Related Accession (Same CDS sequence)	XM_005244951.4 , NM_001973.4 , NM_001973.3 , XM_005244950.4
Accession Version	NM_001973.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1296bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-03
Organism	Homo sapiens(human)
Product	ETS domain-containing protein Elk-4 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AI002107.1, AI005122.1, BE675475.1, BF433322.1, BE676052.1, BC040145.1, M85165.1, BE041598.1, AC096533.3 and AL117645.1. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2011 this sequence version replaced NM_001973.2. Transcript Variant: This variant (a) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.612655.1, M85165.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGACAGTG CTATCACCCT GTGGCAGTTC CTTCTTCAGC TCCTGCAGAA GCCTCAGAAC 
AAGCACATGA TCTGTTGGAC CTCTAATGAT GGGCAGTTTA AGCTTTTGCA GGCAGAAGAG 
GTGGCTCGTC TCTGGGGGAT TCGCAAGAAC AAGCCTAACA TGAATTATGA CAAACTCAGC 
CGAGCCCTCA GATACTATTA TGTAAAGAAT ATCATCAAAA AAGTGAATGG TCAGAAGTTT 
GTGTACAAGT TTGTCTCTTA TCCAGAGATT TTGAACATGG ATCCAATGAC AGTGGGCAGG 
ATTGAGGGTG ACTGTGAAAG TTTAAACTTC AGTGAAGTCA GCAGCAGTTC CAAAGATGTG 
GAGAATGGAG GGAAAGATAA ACCACCTCAG CCTGGTGCCA AGACCTCTAG CCGCAATGAC 
TACATACACT CTGGCTTATA TTCTTCATTT ACTCTCAACT CTTTGAACTC CTCCAATGTA 
AAGCTTTTCA AATTGATAAA GACTGAGAAT CCAGCCGAGA AACTGGCAGA GAAAAAATCT 
CCTCAGGAGC CCACACCATC TGTCATCAAA TTTGTCACGA CACCTTCCAA AAAGCCACCG 
GTTGAACCTG TTGCTGCCAC CATTTCAATT GGCCCAAGTA TTTCTCCATC TTCAGAAGAA 
ACTATCCAAG CTTTGGAGAC ATTGGTTTCC CCAAAACTGC CTTCCCTGGA AGCCCCAACC 
TCTGCCTCTA ACGTAATGAC TGCTTTTGCC ACCACACCAC CCATTTCGTC CATACCCCCT 
TTGCAGGAAC CTCCCAGAAC ACCTTCACCA CCACTGAGTT CTCACCCAGA CATCGACACA 
GACATTGATT CAGTGGCTTC TCAGCCAATG GAACTTCCAG AGAATTTGTC ACTGGAGCCT 
AAAGACCAGG ATTCAGTCTT GCTAGAAAAG GACAAAGTAA ATAATTCATC AAGATCCAAG 
AAACCCAAAG GGTTAGAACT GGCACCCACC CTTGTGATCA CGAGCAGTGA TCCAAGCCCA 
CTGGGAATAC TGAGCCCATC TCTCCCTACA GCTTCTCTTA CACCAGCATT TTTTTCACAG 
ACACCCATCA TACTGACTCC AAGCCCCTTG CTCTCCAGTA TCCACTTCTG GAGTACTCTC 
AGTCCTGTTG CTCCCCTAAG TCCAGCCAGA CTGCAAGGTG CTAACACACT TTTCCAGTTT 
CCTTCTGTAC TGAACAGTCA TGGGCCATTC ACTCTGTCTG GGCTGGATGG ACCTTCCACC 
CCTGGCCCAT TTTCCCCAGA CCTACAGAAG ACATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001964.2
CDS	1251..2546
Translation	MDSAITLWQFLLQLLQKPQNKHMICWTSNDGQFKLLQAEEVARLWGIRKNKPNMNYDKLSRALRYYYVKNIIKKVNGQKFVYKFVSYPEILNMDPMTVGRIEGDCESLNFSEVSSSSKDVENGGKDKPPQPGAKTSSRNDYIHSGLYSSFTLNSLNSSNVKLFKLIKTENPAEKLAEKKSPQEPTPSVIKFVTTPSKKPPVEPVAATISIGPSISPSSEETIQALETLVSPKLPSLEAPTSASNVMTAFATTPPISSIPPLQEPPRTPSPPLSSHPDIDTDIDSVASQPMELPENLSLEPKDQDSVLLEKDKVNNSSRSKKPKGLELAPTLVITSSDPSPLGILSPSLPTASLTPAFFSQTPIILTPSPLLSSIHFWSTLSPVAPLSPARLQGANTLFQFPSVLNSHGPFTLSGLDGPSTPGPFSPDLQKT

Target ORF information:

RefSeq Version	NM_001973.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ETS transcription factor ELK4 (ELK4), transcript variant a, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001973.3

ORF Insert Sequence:

ATGGACAGTG CTATCACCCT GTGGCAGTTC CTTCTTCAGC TCCTGCAGAA GCCTCAGAAC 
AAGCACATGA TCTGTTGGAC CTCTAATGAT GGGCAGTTTA AGCTTTTGCA GGCAGAAGAG 
GTGGCTCGTC TCTGGGGGAT TCGCAAGAAC AAGCCTAACA TGAATTATGA CAAACTCAGC 
CGAGCCCTCA GATACTATTA TGTAAAGAAT ATCATCAAAA AAGTGAATGG TCAGAAGTTT 
GTGTACAAGT TTGTCTCTTA TCCAGAGATT TTGAACATGG ATCCAATGAC AGTGGGCAGG 
ATTGAGGGTG ACTGTGAAAG TTTAAACTTC AGTGAAGTCA GCAGCAGTTC CAAAGATGTG 
GAGAATGGAG GGAAAGATAA ACCACCTCAG CCTGGTGCCA AGACCTCTAG CCGCAATGAC 
TACATACACT CTGGCTTATA TTCTTCATTT ACTCTCAACT CTTTGAACTC CTCCAATGTA 
AAGCTTTTCA AATTGATAAA GACTGAGAAT CCAGCCGAGA AACTGGCAGA GAAAAAATCT 
CCTCAGGAGC CCACACCATC TGTCATCAAA TTTGTCACGA CACCTTCCAA AAAGCCACCG 
GTTGAACCTG TTGCTGCCAC CATTTCAATT GGCCCAAGTA TTTCTCCATC TTCAGAAGAA 
ACTATCCAAG CTTTGGAGAC ATTGGTTTCC CCAAAACTGC CTTCCCTGGA AGCCCCAACC 
TCTGCCTCTA ACGTAATGAC TGCTTTTGCC ACCACACCAC CCATTTCGTC CATACCCCCT 
TTGCAGGAAC CTCCCAGAAC ACCTTCACCA CCACTGAGTT CTCACCCAGA CATCGACACA 
GACATTGATT CAGTGGCTTC TCAGCCAATG GAACTTCCAG AGAATTTGTC ACTGGAGCCT 
AAAGACCAGG ATTCAGTCTT GCTAGAAAAG GACAAAGTAA ATAATTCATC AAGATCCAAG 
AAACCCAAAG GGTTAGAACT GGCACCCACC CTTGTGATCA CGAGCAGTGA TCCAAGCCCA 
CTGGGAATAC TGAGCCCATC TCTCCCTACA GCTTCTCTTA CACCAGCATT TTTTTCACAG 
ACACCCATCA TACTGACTCC AAGCCCCTTG CTCTCCAGTA TCCACTTCTG GAGTACTCTC 
AGTCCTGTTG CTCCCCTAAG TCCAGCCAGA CTGCAAGGTG CTAACACACT TTTCCAGTTT 
CCTTCTGTAC TGAACAGTCA TGGGCCATTC ACTCTGTCTG GGCTGGATGG ACCTTCCACC 
CCTGGCCCAT TTTCCCCAGA CCTACAGAAG ACATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ELK4 ( XM_005244951.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005245008.1 Homo sapiens ELK4, ETS transcription factor (ELK4), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu21721
Clone ID Related Accession (Same CDS sequence)	XM_005244951.4 , NM_001973.4 , NM_001973.3 , XM_005244950.4
Accession Version	XM_005244951.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1296bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	ETS domain-containing protein Elk-4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005244951.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACAGTG CTATCACCCT GTGGCAGTTC CTTCTTCAGC TCCTGCAGAA GCCTCAGAAC 
AAGCACATGA TCTGTTGGAC CTCTAATGAT GGGCAGTTTA AGCTTTTGCA GGCAGAAGAG 
GTGGCTCGTC TCTGGGGGAT TCGCAAGAAC AAGCCTAACA TGAATTATGA CAAACTCAGC 
CGAGCCCTCA GATACTATTA TGTAAAGAAT ATCATCAAAA AAGTGAATGG TCAGAAGTTT 
GTGTACAAGT TTGTCTCTTA TCCAGAGATT TTGAACATGG ATCCAATGAC AGTGGGCAGG 
ATTGAGGGTG ACTGTGAAAG TTTAAACTTC AGTGAAGTCA GCAGCAGTTC CAAAGATGTG 
GAGAATGGAG GGAAAGATAA ACCACCTCAG CCTGGTGCCA AGACCTCTAG CCGCAATGAC 
TACATACACT CTGGCTTATA TTCTTCATTT ACTCTCAACT CTTTGAACTC CTCCAATGTA 
AAGCTTTTCA AATTGATAAA GACTGAGAAT CCAGCCGAGA AACTGGCAGA GAAAAAATCT 
CCTCAGGAGC CCACACCATC TGTCATCAAA TTTGTCACGA CACCTTCCAA AAAGCCACCG 
GTTGAACCTG TTGCTGCCAC CATTTCAATT GGCCCAAGTA TTTCTCCATC TTCAGAAGAA 
ACTATCCAAG CTTTGGAGAC ATTGGTTTCC CCAAAACTGC CTTCCCTGGA AGCCCCAACC 
TCTGCCTCTA ACGTAATGAC TGCTTTTGCC ACCACACCAC CCATTTCGTC CATACCCCCT 
TTGCAGGAAC CTCCCAGAAC ACCTTCACCA CCACTGAGTT CTCACCCAGA CATCGACACA 
GACATTGATT CAGTGGCTTC TCAGCCAATG GAACTTCCAG AGAATTTGTC ACTGGAGCCT 
AAAGACCAGG ATTCAGTCTT GCTAGAAAAG GACAAAGTAA ATAATTCATC AAGATCCAAG 
AAACCCAAAG GGTTAGAACT GGCACCCACC CTTGTGATCA CGAGCAGTGA TCCAAGCCCA 
CTGGGAATAC TGAGCCCATC TCTCCCTACA GCTTCTCTTA CACCAGCATT TTTTTCACAG 
ACACCCATCA TACTGACTCC AAGCCCCTTG CTCTCCAGTA TCCACTTCTG GAGTACTCTC 
AGTCCTGTTG CTCCCCTAAG TCCAGCCAGA CTGCAAGGTG CTAACACACT TTTCCAGTTT 
CCTTCTGTAC TGAACAGTCA TGGGCCATTC ACTCTGTCTG GGCTGGATGG ACCTTCCACC 
CCTGGCCCAT TTTCCCCAGA CCTACAGAAG ACATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005245008.1
CDS	955..2250
Translation	MDSAITLWQFLLQLLQKPQNKHMICWTSNDGQFKLLQAEEVARLWGIRKNKPNMNYDKLSRALRYYYVKNIIKKVNGQKFVYKFVSYPEILNMDPMTVGRIEGDCESLNFSEVSSSSKDVENGGKDKPPQPGAKTSSRNDYIHSGLYSSFTLNSLNSSNVKLFKLIKTENPAEKLAEKKSPQEPTPSVIKFVTTPSKKPPVEPVAATISIGPSISPSSEETIQALETLVSPKLPSLEAPTSASNVMTAFATTPPISSIPPLQEPPRTPSPPLSSHPDIDTDIDSVASQPMELPENLSLEPKDQDSVLLEKDKVNNSSRSKKPKGLELAPTLVITSSDPSPLGILSPSLPTASLTPAFFSQTPIILTPSPLLSSIHFWSTLSPVAPLSPARLQGANTLFQFPSVLNSHGPFTLSGLDGPSTPGPFSPDLQKT

Target ORF information:

RefSeq Version	XM_005244951.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ELK4, ETS transcription factor (ELK4), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005244951.4

ORF Insert Sequence:

ATGGACAGTG CTATCACCCT GTGGCAGTTC CTTCTTCAGC TCCTGCAGAA GCCTCAGAAC 
AAGCACATGA TCTGTTGGAC CTCTAATGAT GGGCAGTTTA AGCTTTTGCA GGCAGAAGAG 
GTGGCTCGTC TCTGGGGGAT TCGCAAGAAC AAGCCTAACA TGAATTATGA CAAACTCAGC 
CGAGCCCTCA GATACTATTA TGTAAAGAAT ATCATCAAAA AAGTGAATGG TCAGAAGTTT 
GTGTACAAGT TTGTCTCTTA TCCAGAGATT TTGAACATGG ATCCAATGAC AGTGGGCAGG 
ATTGAGGGTG ACTGTGAAAG TTTAAACTTC AGTGAAGTCA GCAGCAGTTC CAAAGATGTG 
GAGAATGGAG GGAAAGATAA ACCACCTCAG CCTGGTGCCA AGACCTCTAG CCGCAATGAC 
TACATACACT CTGGCTTATA TTCTTCATTT ACTCTCAACT CTTTGAACTC CTCCAATGTA 
AAGCTTTTCA AATTGATAAA GACTGAGAAT CCAGCCGAGA AACTGGCAGA GAAAAAATCT 
CCTCAGGAGC CCACACCATC TGTCATCAAA TTTGTCACGA CACCTTCCAA AAAGCCACCG 
GTTGAACCTG TTGCTGCCAC CATTTCAATT GGCCCAAGTA TTTCTCCATC TTCAGAAGAA 
ACTATCCAAG CTTTGGAGAC ATTGGTTTCC CCAAAACTGC CTTCCCTGGA AGCCCCAACC 
TCTGCCTCTA ACGTAATGAC TGCTTTTGCC ACCACACCAC CCATTTCGTC CATACCCCCT 
TTGCAGGAAC CTCCCAGAAC ACCTTCACCA CCACTGAGTT CTCACCCAGA CATCGACACA 
GACATTGATT CAGTGGCTTC TCAGCCAATG GAACTTCCAG AGAATTTGTC ACTGGAGCCT 
AAAGACCAGG ATTCAGTCTT GCTAGAAAAG GACAAAGTAA ATAATTCATC AAGATCCAAG 
AAACCCAAAG GGTTAGAACT GGCACCCACC CTTGTGATCA CGAGCAGTGA TCCAAGCCCA 
CTGGGAATAC TGAGCCCATC TCTCCCTACA GCTTCTCTTA CACCAGCATT TTTTTCACAG 
ACACCCATCA TACTGACTCC AAGCCCCTTG CTCTCCAGTA TCCACTTCTG GAGTACTCTC 
AGTCCTGTTG CTCCCCTAAG TCCAGCCAGA CTGCAAGGTG CTAACACACT TTTCCAGTTT 
CCTTCTGTAC TGAACAGTCA TGGGCCATTC ACTCTGTCTG GGCTGGATGG ACCTTCCACC 
CCTGGCCCAT TTTCCCCAGA CCTACAGAAG ACATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ELK4 ( XM_005244950.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005245007.1 Homo sapiens ELK4, ETS transcription factor (ELK4), transcript variant X1, mRNA.

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CloneID	OHu21721
Clone ID Related Accession (Same CDS sequence)	XM_005244951.4 , NM_001973.4 , NM_001973.3 , XM_005244950.4
Accession Version	XM_005244950.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1296bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	ETS domain-containing protein Elk-4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005244950.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACAGTG CTATCACCCT GTGGCAGTTC CTTCTTCAGC TCCTGCAGAA GCCTCAGAAC 
AAGCACATGA TCTGTTGGAC CTCTAATGAT GGGCAGTTTA AGCTTTTGCA GGCAGAAGAG 
GTGGCTCGTC TCTGGGGGAT TCGCAAGAAC AAGCCTAACA TGAATTATGA CAAACTCAGC 
CGAGCCCTCA GATACTATTA TGTAAAGAAT ATCATCAAAA AAGTGAATGG TCAGAAGTTT 
GTGTACAAGT TTGTCTCTTA TCCAGAGATT TTGAACATGG ATCCAATGAC AGTGGGCAGG 
ATTGAGGGTG ACTGTGAAAG TTTAAACTTC AGTGAAGTCA GCAGCAGTTC CAAAGATGTG 
GAGAATGGAG GGAAAGATAA ACCACCTCAG CCTGGTGCCA AGACCTCTAG CCGCAATGAC 
TACATACACT CTGGCTTATA TTCTTCATTT ACTCTCAACT CTTTGAACTC CTCCAATGTA 
AAGCTTTTCA AATTGATAAA GACTGAGAAT CCAGCCGAGA AACTGGCAGA GAAAAAATCT 
CCTCAGGAGC CCACACCATC TGTCATCAAA TTTGTCACGA CACCTTCCAA AAAGCCACCG 
GTTGAACCTG TTGCTGCCAC CATTTCAATT GGCCCAAGTA TTTCTCCATC TTCAGAAGAA 
ACTATCCAAG CTTTGGAGAC ATTGGTTTCC CCAAAACTGC CTTCCCTGGA AGCCCCAACC 
TCTGCCTCTA ACGTAATGAC TGCTTTTGCC ACCACACCAC CCATTTCGTC CATACCCCCT 
TTGCAGGAAC CTCCCAGAAC ACCTTCACCA CCACTGAGTT CTCACCCAGA CATCGACACA 
GACATTGATT CAGTGGCTTC TCAGCCAATG GAACTTCCAG AGAATTTGTC ACTGGAGCCT 
AAAGACCAGG ATTCAGTCTT GCTAGAAAAG GACAAAGTAA ATAATTCATC AAGATCCAAG 
AAACCCAAAG GGTTAGAACT GGCACCCACC CTTGTGATCA CGAGCAGTGA TCCAAGCCCA 
CTGGGAATAC TGAGCCCATC TCTCCCTACA GCTTCTCTTA CACCAGCATT TTTTTCACAG 
ACACCCATCA TACTGACTCC AAGCCCCTTG CTCTCCAGTA TCCACTTCTG GAGTACTCTC 
AGTCCTGTTG CTCCCCTAAG TCCAGCCAGA CTGCAAGGTG CTAACACACT TTTCCAGTTT 
CCTTCTGTAC TGAACAGTCA TGGGCCATTC ACTCTGTCTG GGCTGGATGG ACCTTCCACC 
CCTGGCCCAT TTTCCCCAGA CCTACAGAAG ACATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005245007.1
CDS	161..1456
Translation	MDSAITLWQFLLQLLQKPQNKHMICWTSNDGQFKLLQAEEVARLWGIRKNKPNMNYDKLSRALRYYYVKNIIKKVNGQKFVYKFVSYPEILNMDPMTVGRIEGDCESLNFSEVSSSSKDVENGGKDKPPQPGAKTSSRNDYIHSGLYSSFTLNSLNSSNVKLFKLIKTENPAEKLAEKKSPQEPTPSVIKFVTTPSKKPPVEPVAATISIGPSISPSSEETIQALETLVSPKLPSLEAPTSASNVMTAFATTPPISSIPPLQEPPRTPSPPLSSHPDIDTDIDSVASQPMELPENLSLEPKDQDSVLLEKDKVNNSSRSKKPKGLELAPTLVITSSDPSPLGILSPSLPTASLTPAFFSQTPIILTPSPLLSSIHFWSTLSPVAPLSPARLQGANTLFQFPSVLNSHGPFTLSGLDGPSTPGPFSPDLQKT

Target ORF information:

RefSeq Version	XM_005244950.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ELK4, ETS transcription factor (ELK4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005244950.4

ORF Insert Sequence:

ATGGACAGTG CTATCACCCT GTGGCAGTTC CTTCTTCAGC TCCTGCAGAA GCCTCAGAAC 
AAGCACATGA TCTGTTGGAC CTCTAATGAT GGGCAGTTTA AGCTTTTGCA GGCAGAAGAG 
GTGGCTCGTC TCTGGGGGAT TCGCAAGAAC AAGCCTAACA TGAATTATGA CAAACTCAGC 
CGAGCCCTCA GATACTATTA TGTAAAGAAT ATCATCAAAA AAGTGAATGG TCAGAAGTTT 
GTGTACAAGT TTGTCTCTTA TCCAGAGATT TTGAACATGG ATCCAATGAC AGTGGGCAGG 
ATTGAGGGTG ACTGTGAAAG TTTAAACTTC AGTGAAGTCA GCAGCAGTTC CAAAGATGTG 
GAGAATGGAG GGAAAGATAA ACCACCTCAG CCTGGTGCCA AGACCTCTAG CCGCAATGAC 
TACATACACT CTGGCTTATA TTCTTCATTT ACTCTCAACT CTTTGAACTC CTCCAATGTA 
AAGCTTTTCA AATTGATAAA GACTGAGAAT CCAGCCGAGA AACTGGCAGA GAAAAAATCT 
CCTCAGGAGC CCACACCATC TGTCATCAAA TTTGTCACGA CACCTTCCAA AAAGCCACCG 
GTTGAACCTG TTGCTGCCAC CATTTCAATT GGCCCAAGTA TTTCTCCATC TTCAGAAGAA 
ACTATCCAAG CTTTGGAGAC ATTGGTTTCC CCAAAACTGC CTTCCCTGGA AGCCCCAACC 
TCTGCCTCTA ACGTAATGAC TGCTTTTGCC ACCACACCAC CCATTTCGTC CATACCCCCT 
TTGCAGGAAC CTCCCAGAAC ACCTTCACCA CCACTGAGTT CTCACCCAGA CATCGACACA 
GACATTGATT CAGTGGCTTC TCAGCCAATG GAACTTCCAG AGAATTTGTC ACTGGAGCCT 
AAAGACCAGG ATTCAGTCTT GCTAGAAAAG GACAAAGTAA ATAATTCATC AAGATCCAAG 
AAACCCAAAG GGTTAGAACT GGCACCCACC CTTGTGATCA CGAGCAGTGA TCCAAGCCCA 
CTGGGAATAC TGAGCCCATC TCTCCCTACA GCTTCTCTTA CACCAGCATT TTTTTCACAG 
ACACCCATCA TACTGACTCC AAGCCCCTTG CTCTCCAGTA TCCACTTCTG GAGTACTCTC 
AGTCCTGTTG CTCCCCTAAG TCCAGCCAGA CTGCAAGGTG CTAACACACT TTTCCAGTTT 
CCTTCTGTAC TGAACAGTCA TGGGCCATTC ACTCTGTCTG GGCTGGATGG ACCTTCCACC 
CCTGGCCCAT TTTCCCCAGA CCTACAGAAG ACATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ELK4 ( NM_001973.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001964.2 Homo sapiens ETS transcription factor ELK4 (ELK4), transcript variant a, mRNA.

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CloneID	OHu21721
Clone ID Related Accession (Same CDS sequence)	XM_005244951.4 , NM_001973.4 , NM_001973.3 , XM_005244950.4
Accession Version	NM_001973.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1296bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	ETS domain-containing protein Elk-4 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC096533.3. This sequence is a reference standard in the RefSeqGene project. On Jul 25, 2019 this sequence version replaced NM_001973.3. Transcript Variant: This variant (a) encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DRR138518.63354.1, DRR138518.706095.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGACAGTG CTATCACCCT GTGGCAGTTC CTTCTTCAGC TCCTGCAGAA GCCTCAGAAC 
AAGCACATGA TCTGTTGGAC CTCTAATGAT GGGCAGTTTA AGCTTTTGCA GGCAGAAGAG 
GTGGCTCGTC TCTGGGGGAT TCGCAAGAAC AAGCCTAACA TGAATTATGA CAAACTCAGC 
CGAGCCCTCA GATACTATTA TGTAAAGAAT ATCATCAAAA AAGTGAATGG TCAGAAGTTT 
GTGTACAAGT TTGTCTCTTA TCCAGAGATT TTGAACATGG ATCCAATGAC AGTGGGCAGG 
ATTGAGGGTG ACTGTGAAAG TTTAAACTTC AGTGAAGTCA GCAGCAGTTC CAAAGATGTG 
GAGAATGGAG GGAAAGATAA ACCACCTCAG CCTGGTGCCA AGACCTCTAG CCGCAATGAC 
TACATACACT CTGGCTTATA TTCTTCATTT ACTCTCAACT CTTTGAACTC CTCCAATGTA 
AAGCTTTTCA AATTGATAAA GACTGAGAAT CCAGCCGAGA AACTGGCAGA GAAAAAATCT 
CCTCAGGAGC CCACACCATC TGTCATCAAA TTTGTCACGA CACCTTCCAA AAAGCCACCG 
GTTGAACCTG TTGCTGCCAC CATTTCAATT GGCCCAAGTA TTTCTCCATC TTCAGAAGAA 
ACTATCCAAG CTTTGGAGAC ATTGGTTTCC CCAAAACTGC CTTCCCTGGA AGCCCCAACC 
TCTGCCTCTA ACGTAATGAC TGCTTTTGCC ACCACACCAC CCATTTCGTC CATACCCCCT 
TTGCAGGAAC CTCCCAGAAC ACCTTCACCA CCACTGAGTT CTCACCCAGA CATCGACACA 
GACATTGATT CAGTGGCTTC TCAGCCAATG GAACTTCCAG AGAATTTGTC ACTGGAGCCT 
AAAGACCAGG ATTCAGTCTT GCTAGAAAAG GACAAAGTAA ATAATTCATC AAGATCCAAG 
AAACCCAAAG GGTTAGAACT GGCACCCACC CTTGTGATCA CGAGCAGTGA TCCAAGCCCA 
CTGGGAATAC TGAGCCCATC TCTCCCTACA GCTTCTCTTA CACCAGCATT TTTTTCACAG 
ACACCCATCA TACTGACTCC AAGCCCCTTG CTCTCCAGTA TCCACTTCTG GAGTACTCTC 
AGTCCTGTTG CTCCCCTAAG TCCAGCCAGA CTGCAAGGTG CTAACACACT TTTCCAGTTT 
CCTTCTGTAC TGAACAGTCA TGGGCCATTC ACTCTGTCTG GGCTGGATGG ACCTTCCACC 
CCTGGCCCAT TTTCCCCAGA CCTACAGAAG ACATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001964.2
CDS	390..1685
Translation	MDSAITLWQFLLQLLQKPQNKHMICWTSNDGQFKLLQAEEVARLWGIRKNKPNMNYDKLSRALRYYYVKNIIKKVNGQKFVYKFVSYPEILNMDPMTVGRIEGDCESLNFSEVSSSSKDVENGGKDKPPQPGAKTSSRNDYIHSGLYSSFTLNSLNSSNVKLFKLIKTENPAEKLAEKKSPQEPTPSVIKFVTTPSKKPPVEPVAATISIGPSISPSSEETIQALETLVSPKLPSLEAPTSASNVMTAFATTPPISSIPPLQEPPRTPSPPLSSHPDIDTDIDSVASQPMELPENLSLEPKDQDSVLLEKDKVNNSSRSKKPKGLELAPTLVITSSDPSPLGILSPSLPTASLTPAFFSQTPIILTPSPLLSSIHFWSTLSPVAPLSPARLQGANTLFQFPSVLNSHGPFTLSGLDGPSTPGPFSPDLQKT

Target ORF information:

RefSeq Version	NM_001973.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ETS transcription factor ELK4 (ELK4), transcript variant a, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001973.4

ORF Insert Sequence:

ATGGACAGTG CTATCACCCT GTGGCAGTTC CTTCTTCAGC TCCTGCAGAA GCCTCAGAAC 
AAGCACATGA TCTGTTGGAC CTCTAATGAT GGGCAGTTTA AGCTTTTGCA GGCAGAAGAG 
GTGGCTCGTC TCTGGGGGAT TCGCAAGAAC AAGCCTAACA TGAATTATGA CAAACTCAGC 
CGAGCCCTCA GATACTATTA TGTAAAGAAT ATCATCAAAA AAGTGAATGG TCAGAAGTTT 
GTGTACAAGT TTGTCTCTTA TCCAGAGATT TTGAACATGG ATCCAATGAC AGTGGGCAGG 
ATTGAGGGTG ACTGTGAAAG TTTAAACTTC AGTGAAGTCA GCAGCAGTTC CAAAGATGTG 
GAGAATGGAG GGAAAGATAA ACCACCTCAG CCTGGTGCCA AGACCTCTAG CCGCAATGAC 
TACATACACT CTGGCTTATA TTCTTCATTT ACTCTCAACT CTTTGAACTC CTCCAATGTA 
AAGCTTTTCA AATTGATAAA GACTGAGAAT CCAGCCGAGA AACTGGCAGA GAAAAAATCT 
CCTCAGGAGC CCACACCATC TGTCATCAAA TTTGTCACGA CACCTTCCAA AAAGCCACCG 
GTTGAACCTG TTGCTGCCAC CATTTCAATT GGCCCAAGTA TTTCTCCATC TTCAGAAGAA 
ACTATCCAAG CTTTGGAGAC ATTGGTTTCC CCAAAACTGC CTTCCCTGGA AGCCCCAACC 
TCTGCCTCTA ACGTAATGAC TGCTTTTGCC ACCACACCAC CCATTTCGTC CATACCCCCT 
TTGCAGGAAC CTCCCAGAAC ACCTTCACCA CCACTGAGTT CTCACCCAGA CATCGACACA 
GACATTGATT CAGTGGCTTC TCAGCCAATG GAACTTCCAG AGAATTTGTC ACTGGAGCCT 
AAAGACCAGG ATTCAGTCTT GCTAGAAAAG GACAAAGTAA ATAATTCATC AAGATCCAAG 
AAACCCAAAG GGTTAGAACT GGCACCCACC CTTGTGATCA CGAGCAGTGA TCCAAGCCCA 
CTGGGAATAC TGAGCCCATC TCTCCCTACA GCTTCTCTTA CACCAGCATT TTTTTCACAG 
ACACCCATCA TACTGACTCC AAGCCCCTTG CTCTCCAGTA TCCACTTCTG GAGTACTCTC 
AGTCCTGTTG CTCCCCTAAG TCCAGCCAGA CTGCAAGGTG CTAACACACT TTTCCAGTTT 
CCTTCTGTAC TGAACAGTCA TGGGCCATTC ACTCTGTCTG GGCTGGATGG ACCTTCCACC 
CCTGGCCCAT TTTCCCCAGA CCTACAGAAG ACATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ELK4 ( XM_017000580.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016856069.1 Homo sapiens ELK4, ETS transcription factor (ELK4), transcript variant X8, mRNA.

Price & Availability↑

CloneID	OHu83299
Clone ID Related Accession (Same CDS sequence)	XM_017000580.1
Accession Version	XM_017000580.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1242bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	ETS domain-containing protein Elk-4 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACAGTG CTATCACCCT GTGGCAGTTC CTTCTTCAGC TCCTGCAGAA GCCTCAGAAC 
AAGCACATGA TCTGTTGGAC CTCTAATGAT GGGCAGTTTA AGCTTTTGCA GGCAGAAGAG 
GTGGCTCGTC TCTGGGGGAT TCGCAAGAAC AAGCCTAACA TGAATTATGA CAAACTCAGC 
CGAGCCCTCA GATACTATTA TGTAAAGAAT ATCATCAAAA AAGTGAATGG TCAGAAGTTT 
GTGTACAAGT TTGTCTCTTA TCCAGAGATT TTGAACATGG ATCCAATGAC AGTGGGCAGG 
ATTGAGGGTG ACTGTGAAAG TTTAAACTTC AGTGAAGTCA GCAGCAGTTC CAAAGATGTG 
GAGAATGGAG GGAAAGATAA ACCACCTCAG CCTGGTGCCA AGACCTCTAG CCGCAATGAC 
TACATACACT CTGGCTTATA TTCTTCATTT ACTCTCAACT CTTTGAACTC CTCCAATGTA 
AAGCTTTTCA AATTGATAAA GACTGAGAAT CCAGCCGAGA AACTGGCAGA GAAAAAATCT 
CCTCAGGAGC CCACACCATC TGTCATCAAA TTTGTCACGA CACCTTCCAA AAAGCCACCG 
GTTGAACCTG TTGCTGCCAC CATTTCAATT GGCCCAAGTA TTTCTCCATC TTCAGAAGAA 
ACTATCCAAG CTTTGGAGAC ATTGGTTTCC CCAAAACTGC CTTCCCTGGA AGCCCCAACC 
TCTGCCTCTA ACGTAATGAC TGCTTTTGCC ACCACACCAC CCATTTCGTC CATACCCCCT 
TTGCAGGAAC CTCCCAGAAC ACCTTCACCA CCACTGAGTT CTCACCCAGA CATCGACACA 
GACATTGATT CAGTGGCTTC TCAGCCAATG GAACTTCCAG AGAATTTGTC ACTGGAGCCT 
AAAGACCAGG ATTCAGTCTT GCTAGAAAAG GACAAAGTAA ATAATTCATC AAGATCCAAG 
AAACCCAAAG GGTTAGAACT GGCACCCACC CTTGTGATCA CGAGCAGTGA TCCAAGCCCA 
CTGGGAATAC TGAGCCCATC TCTCCCTACA GCTTCTCTTA CACCAGCATT TTTTTCACAG 
ACACCCATCA TACTGACTCC AAGCCCCTTG CTCTCCAGTA TCCACTTCTG GAGTACTCTC 
AGTCCTGTTG CTCCCCTAAG TCCAGCCAGA CTGCAAGGTG CTAACACACT TTTCCAGATG 
GAGTCCTCAC CATGTCACCC AGGCTGGAGT GCAGTGGCAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016856069.1
CDS	1405..2646
Translation	MDSAITLWQFLLQLLQKPQNKHMICWTSNDGQFKLLQAEEVARLWGIRKNKPNMNYDKLSRALRYYYVKNIIKKVNGQKFVYKFVSYPEILNMDPMTVGRIEGDCESLNFSEVSSSSKDVENGGKDKPPQPGAKTSSRNDYIHSGLYSSFTLNSLNSSNVKLFKLIKTENPAEKLAEKKSPQEPTPSVIKFVTTPSKKPPVEPVAATISIGPSISPSSEETIQALETLVSPKLPSLEAPTSASNVMTAFATTPPISSIPPLQEPPRTPSPPLSSHPDIDTDIDSVASQPMELPENLSLEPKDQDSVLLEKDKVNNSSRSKKPKGLELAPTLVITSSDPSPLGILSPSLPTASLTPAFFSQTPIILTPSPLLSSIHFWSTLSPVAPLSPARLQGANTLFQMESSPCHPGWSAVA

Target ORF information:

RefSeq Version	XM_017000580.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ELK4, ETS transcription factor (ELK4), transcript variant X8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017000580.1

ORF Insert Sequence:

ATGGACAGTG CTATCACCCT GTGGCAGTTC CTTCTTCAGC TCCTGCAGAA GCCTCAGAAC 
AAGCACATGA TCTGTTGGAC CTCTAATGAT GGGCAGTTTA AGCTTTTGCA GGCAGAAGAG 
GTGGCTCGTC TCTGGGGGAT TCGCAAGAAC AAGCCTAACA TGAATTATGA CAAACTCAGC 
CGAGCCCTCA GATACTATTA TGTAAAGAAT ATCATCAAAA AAGTGAATGG TCAGAAGTTT 
GTGTACAAGT TTGTCTCTTA TCCAGAGATT TTGAACATGG ATCCAATGAC AGTGGGCAGG 
ATTGAGGGTG ACTGTGAAAG TTTAAACTTC AGTGAAGTCA GCAGCAGTTC CAAAGATGTG 
GAGAATGGAG GGAAAGATAA ACCACCTCAG CCTGGTGCCA AGACCTCTAG CCGCAATGAC 
TACATACACT CTGGCTTATA TTCTTCATTT ACTCTCAACT CTTTGAACTC CTCCAATGTA 
AAGCTTTTCA AATTGATAAA GACTGAGAAT CCAGCCGAGA AACTGGCAGA GAAAAAATCT 
CCTCAGGAGC CCACACCATC TGTCATCAAA TTTGTCACGA CACCTTCCAA AAAGCCACCG 
GTTGAACCTG TTGCTGCCAC CATTTCAATT GGCCCAAGTA TTTCTCCATC TTCAGAAGAA 
ACTATCCAAG CTTTGGAGAC ATTGGTTTCC CCAAAACTGC CTTCCCTGGA AGCCCCAACC 
TCTGCCTCTA ACGTAATGAC TGCTTTTGCC ACCACACCAC CCATTTCGTC CATACCCCCT 
TTGCAGGAAC CTCCCAGAAC ACCTTCACCA CCACTGAGTT CTCACCCAGA CATCGACACA 
GACATTGATT CAGTGGCTTC TCAGCCAATG GAACTTCCAG AGAATTTGTC ACTGGAGCCT 
AAAGACCAGG ATTCAGTCTT GCTAGAAAAG GACAAAGTAA ATAATTCATC AAGATCCAAG 
AAACCCAAAG GGTTAGAACT GGCACCCACC CTTGTGATCA CGAGCAGTGA TCCAAGCCCA 
CTGGGAATAC TGAGCCCATC TCTCCCTACA GCTTCTCTTA CACCAGCATT TTTTTCACAG 
ACACCCATCA TACTGACTCC AAGCCCCTTG CTCTCCAGTA TCCACTTCTG GAGTACTCTC 
AGTCCTGTTG CTCCCCTAAG TCCAGCCAGA CTGCAAGGTG CTAACACACT TTTCCAGATG 
GAGTCCTCAC CATGTCACCC AGGCTGGAGT GCAGTGGCAT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Ubiquitin-specific peptidase 7 (USP7)-mediated deubiquitination of the histone deacetylase SIRT7 regulates gluconeogenesis.
The Journal of biological chemistry292(32)13296-13311(2017 08)
Jiang L,Xiong J,Zhan J,Yuan F,Tang M,Zhang C,Cao Z,Chen Y,Lu X,Li Y,Wang H,Wang L,Wang J,Zhu WG,Wang H

Cyclin-dependent kinase 2 (CDK2) is a key mediator for EGF-induced cell transformation mediated through the ELK4/c-Fos signaling pathway.
Oncogene35(9)1170-9(2016 Mar)
Peng C,Zeng W,Su J,Kuang Y,He Y,Zhao S,Zhang J,Ma W,Bode AM,Dong Z,Chen X

Role of CTCF in Regulating SLC45A3-ELK4 Chimeric RNA.
PloS one11(3)e0150382(2016)
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SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation.
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Chimeric transcript generated by cis-splicing of adjacent genes regulates prostate cancer cell proliferation.
Cancer discovery2(7)598-607(2012 Jul)
Zhang Y,Gong M,Yuan H,Park HG,Frierson HF,Li H

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ELK4 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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