RHOXF1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RHOXF1
Entrez Gene ID	158800
Full Name	Rhox homeobox family member 1
Synonyms	OTEX,PEPP1
General protein information	Preferred Names Rhox homeobox family member 1 Names rhox homeobox family member 1 PEPP subfamily gene 1 ovary-, testis- and epididymis-expressed gene protein paired-like homeobox protein PEPP-1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq24
Summary	This gene is a member of the PEPP subfamily of paired-like homoebox genes. The gene may be regulated by androgens and epigenetic mechanisms. The encoded nuclear protein is likely a transcription factor that may play a role in human reproduction. [provided by RefSeq, Dec 2012].
Disorder MIM:	300446

mRNA and Protein(s)

mRNA	Protein	Name
NM_139282.2	NP_644811.1	rhox homeobox family member 1
NM_139282.3	NP_644811.1	rhox homeobox family member 1
XM_011531281.2	XP_011529583.1	rhox homeobox family member 1 isoform X1

Pathways from BioSystems

Homologies

	RHOXF1	XP_001084578.1
Pan troglodytes (chimpanzee)	RHOXF1	XP_001138831.1
Homo sapiens (human)	RHOXF1	NP_644811.1
Canis lupus familiaris (dog)	LOC481034	XP_538156.4

Gene Ontology
Bibliography

Related articles in PubMed

Homeobox gene Rhox5 is regulated by epigenetic mechanisms in cancer and stem cells and promotes cancer growth.
Li Q, O'Malley ME, Bartlett DL, Guo ZS
Molecular cancer1063(2011 May)

Three epigenetic drugs up-regulate homeobox gene Rhox5 in cancer cells through overlapping and distinct molecular mechanisms.
Li Q, Bartlett DL, Gorry MC, O'Malley ME, Guo ZS
Molecular pharmacology76(5)1072-81(2009 Nov)

A census of human transcription factors: function, expression and evolution.
Vaquerizas JM, Kummerfeld SK, Teichmann SA, Luscombe NM
Nature reviews. Genetics10(4)252-63(2009 04)

Conservation and variation of gene regulation in embryonic stem cells assessed by comparative genomics.
Zhan M, Miura T, Xu X, Rao MS
Cell biochemistry and biophysics43(3)379-405(2005)

Two novel human X-linked homeobox genes, hPEPP1 and hPEPP2, selectively expressed in the testis.
Wayne CM, MacLean JA, Cornwall G, Wilkinson MF
Gene301(1-2)1-11(2002 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

cloning and characterization of human OTEX
Title: OTEX, an androgen-regulated human member of the paired-like class of homeobox genes.

The following RHOXF1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RHOXF1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu06296	NM_139282.3 Latest version!	Homo sapiens Rhox homeobox family member 1 (RHOXF1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu77013	XM_011531281.2 Latest version!	Homo sapiens Rhox homeobox family member 1 (RHOXF1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu06296	NM_139282.2	Homo sapiens Rhox homeobox family member 1 (RHOXF1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RHOXF1 ( NM_139282.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_644811.1 Homo sapiens Rhox homeobox family member 1 (RHOXF1), mRNA.

Price & Availability↑

CloneID	OHu06296
Clone ID Related Accession (Same CDS sequence)	NM_139282.2 , NM_139282.3
Accession Version	NM_139282.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 555bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-24
Organism	Homo sapiens(human)
Product	rhox homeobox family member 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY099086.1 and BE675048.1. On Dec 14, 2012 this sequence version replaced NM_139282.1. ##Evidence-Data-START## Transcript exon combination :: AY099086.1, BC103857.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGCGTT CGCTCGTCCA CGACACCGTG TTCTACTGCC TGAGTGTATA CCAGGTAAAA 
ATAAGCCCCA CACCTCAGCT GGGGGCAGCA TCAAGCGCAG AAGGCCATGT TGGCCAAGGA 
GCTCCAGGCC TCATGGGTAA TATGAACCCT GAGGGCGGTG TGAACCACGA GAACGGCATG 
AACCGCGATG GCGGCATGAT CCCCGAGGGC GGCGGTGGAA ACCAGGAGCC TCGGCAGCAG 
CCGCAGCCCC CGCCGGAGGA GCCGGCCCAG GCGGCCATGG AGGGTCCGCA GCCCGAGAAC 
ATGCAGCCAC GAACTCGGCG CACGAAGTTC ACGCTGTTGC AGGTGGAGGA GCTGGAAAGT 
GTTTTCCGAC ACACTCAATA CCCTGATGTG CCCACAAGAA GGGAACTTGC CGAAAACTTA 
GGTGTGACTG AAGACAAAGT GCGGGTTTGG TTTAAGAATA AAAGGGCCAG ATGTAGGCGA 
CATCAGAGAG AATTAATGCT CGCCAATGAA CTACGTGCTG ACCCAGACGA CTGTGTCTAC 
ATCGTCGTGG ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_644811.1
CDS	76..630
Translation	MARSLVHDTVFYCLSVYQVKISPTPQLGAASSAEGHVGQGAPGLMGNMNPEGGVNHENGMNRDGGMIPEGGGGNQEPRQQPQPPPEEPAQAAMEGPQPENMQPRTRRTKFTLLQVEELESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRRHQRELMLANELRADPDDCVYIVVD

Target ORF information:

RefSeq Version	NM_139282.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Rhox homeobox family member 1 (RHOXF1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139282.2

ORF Insert Sequence:

ATGGCGCGTT CGCTCGTCCA CGACACCGTG TTCTACTGCC TGAGTGTATA CCAGGTAAAA 
ATAAGCCCCA CACCTCAGCT GGGGGCAGCA TCAAGCGCAG AAGGCCATGT TGGCCAAGGA 
GCTCCAGGCC TCATGGGTAA TATGAACCCT GAGGGCGGTG TGAACCACGA GAACGGCATG 
AACCGCGATG GCGGCATGAT CCCCGAGGGC GGCGGTGGAA ACCAGGAGCC TCGGCAGCAG 
CCGCAGCCCC CGCCGGAGGA GCCGGCCCAG GCGGCCATGG AGGGTCCGCA GCCCGAGAAC 
ATGCAGCCAC GAACTCGGCG CACGAAGTTC ACGCTGTTGC AGGTGGAGGA GCTGGAAAGT 
GTTTTCCGAC ACACTCAATA CCCTGATGTG CCCACAAGAA GGGAACTTGC CGAAAACTTA 
GGTGTGACTG AAGACAAAGT GCGGGTTTGG TTTAAGAATA AAAGGGCCAG ATGTAGGCGA 
CATCAGAGAG AATTAATGCT CGCCAATGAA CTACGTGCTG ACCCAGACGA CTGTGTCTAC 
ATCGTCGTGG ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RHOXF1 ( NM_139282.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_644811.1 Homo sapiens Rhox homeobox family member 1 (RHOXF1), mRNA.

Price & Availability↑

CloneID	OHu06296
Clone ID Related Accession (Same CDS sequence)	NM_139282.2 , NM_139282.3
Accession Version	NM_139282.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 555bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	rhox homeobox family member 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY099086.1, BE675048.1 and AC240732.2. On May 17, 2019 this sequence version replaced NM_139282.2. ##Evidence-Data-START## Transcript exon combination :: BC069529.1, AY099086.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000217999.3/ ENSP00000217999.1 RefSeq Select criteria :: based on expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGCGTT CGCTCGTCCA CGACACCGTG TTCTACTGCC TGAGTGTATA CCAGGTAAAA 
ATAAGCCCCA CACCTCAGCT GGGGGCAGCA TCAAGCGCAG AAGGCCATGT TGGCCAAGGA 
GCTCCAGGCC TCATGGGTAA TATGAACCCT GAGGGCGGTG TGAACCACGA GAACGGCATG 
AACCGCGATG GCGGCATGAT CCCCGAGGGC GGCGGTGGAA ACCAGGAGCC TCGGCAGCAG 
CCGCAGCCCC CGCCGGAGGA GCCGGCCCAG GCGGCCATGG AGGGTCCGCA GCCCGAGAAC 
ATGCAGCCAC GAACTCGGCG CACGAAGTTC ACGCTGTTGC AGGTGGAGGA GCTGGAAAGT 
GTTTTCCGAC ACACTCAATA CCCTGATGTG CCCACAAGAA GGGAACTTGC CGAAAACTTA 
GGTGTGACTG AAGACAAAGT GCGGGTTTGG TTTAAGAATA AAAGGGCCAG ATGTAGGCGA 
CATCAGAGAG AATTAATGCT CGCCAATGAA CTACGTGCTG ACCCAGACGA CTGTGTCTAC 
ATCGTCGTGG ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_644811.1
CDS	52..606
Translation	MARSLVHDTVFYCLSVYQVKISPTPQLGAASSAEGHVGQGAPGLMGNMNPEGGVNHENGMNRDGGMIPEGGGGNQEPRQQPQPPPEEPAQAAMEGPQPENMQPRTRRTKFTLLQVEELESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRRHQRELMLANELRADPDDCVYIVVD

Target ORF information:

RefSeq Version	NM_139282.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Rhox homeobox family member 1 (RHOXF1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_139282.3

ORF Insert Sequence:

ATGGCGCGTT CGCTCGTCCA CGACACCGTG TTCTACTGCC TGAGTGTATA CCAGGTAAAA 
ATAAGCCCCA CACCTCAGCT GGGGGCAGCA TCAAGCGCAG AAGGCCATGT TGGCCAAGGA 
GCTCCAGGCC TCATGGGTAA TATGAACCCT GAGGGCGGTG TGAACCACGA GAACGGCATG 
AACCGCGATG GCGGCATGAT CCCCGAGGGC GGCGGTGGAA ACCAGGAGCC TCGGCAGCAG 
CCGCAGCCCC CGCCGGAGGA GCCGGCCCAG GCGGCCATGG AGGGTCCGCA GCCCGAGAAC 
ATGCAGCCAC GAACTCGGCG CACGAAGTTC ACGCTGTTGC AGGTGGAGGA GCTGGAAAGT 
GTTTTCCGAC ACACTCAATA CCCTGATGTG CCCACAAGAA GGGAACTTGC CGAAAACTTA 
GGTGTGACTG AAGACAAAGT GCGGGTTTGG TTTAAGAATA AAAGGGCCAG ATGTAGGCGA 
CATCAGAGAG AATTAATGCT CGCCAATGAA CTACGTGCTG ACCCAGACGA CTGTGTCTAC 
ATCGTCGTGG ACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RHOXF1 ( XM_011531281.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011529583.1 Homo sapiens Rhox homeobox family member 1 (RHOXF1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu77013
Clone ID Related Accession (Same CDS sequence)	XM_011531281.2
Accession Version	XM_011531281.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 639bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	rhox homeobox family member 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011531281.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTCAGAA TCACCATGAA GACGAGAGCT ATCTCTCTTG CTGCAGACGC CACGGAGTTT 
GTGCAGGGGC GCAGCGCTCC AGCCATGGCG CGTTCGCTCG TCCACGACAC CGTGTTCTAC 
TGCCTGAGTG TATACCAGGT AAAAATAAGC CCCACACCTC AGCTGGGGGC AGCATCAAGC 
GCAGAAGGCC ATGTTGGCCA AGGAGCTCCA GGCCTCATGG GTAATATGAA CCCTGAGGGC 
GGTGTGAACC ACGAGAACGG CATGAACCGC GATGGCGGCA TGATCCCCGA GGGCGGCGGT 
GGAAACCAGG AGCCTCGGCA GCAGCCGCAG CCCCCGCCGG AGGAGCCGGC CCAGGCGGCC 
ATGGAGGGTC CGCAGCCCGA GAACATGCAG CCACGAACTC GGCGCACGAA GTTCACGCTG 
TTGCAGGTGG AGGAGCTGGA AAGTGTTTTC CGACACACTC AATACCCTGA TGTGCCCACA 
AGAAGGGAAC TTGCCGAAAA CTTAGGTGTG ACTGAAGACA AAGTGCGGGT TTGGTTTAAG 
AATAAAAGGG CCAGATGTAG GCGACATCAG AGAGAATTAA TGCTCGCCAA TGAACTACGT 
GCTGACCCAG ACGACTGTGT CTACATCGTC GTGGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011529583.1
CDS	43..681
Translation	MLRITMKTRAISLAADATEFVQGRSAPAMARSLVHDTVFYCLSVYQVKISPTPQLGAASSAEGHVGQGAPGLMGNMNPEGGVNHENGMNRDGGMIPEGGGGNQEPRQQPQPPPEEPAQAAMEGPQPENMQPRTRRTKFTLLQVEELESVFRHTQYPDVPTRRELAENLGVTEDKVRVWFKNKRARCRRHQRELMLANELRADPDDCVYIVVD

Target ORF information:

RefSeq Version	XM_011531281.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Rhox homeobox family member 1 (RHOXF1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011531281.2

ORF Insert Sequence:

ATGCTCAGAA TCACCATGAA GACGAGAGCT ATCTCTCTTG CTGCAGACGC CACGGAGTTT 
GTGCAGGGGC GCAGCGCTCC AGCCATGGCG CGTTCGCTCG TCCACGACAC CGTGTTCTAC 
TGCCTGAGTG TATACCAGGT AAAAATAAGC CCCACACCTC AGCTGGGGGC AGCATCAAGC 
GCAGAAGGCC ATGTTGGCCA AGGAGCTCCA GGCCTCATGG GTAATATGAA CCCTGAGGGC 
GGTGTGAACC ACGAGAACGG CATGAACCGC GATGGCGGCA TGATCCCCGA GGGCGGCGGT 
GGAAACCAGG AGCCTCGGCA GCAGCCGCAG CCCCCGCCGG AGGAGCCGGC CCAGGCGGCC 
ATGGAGGGTC CGCAGCCCGA GAACATGCAG CCACGAACTC GGCGCACGAA GTTCACGCTG 
TTGCAGGTGG AGGAGCTGGA AAGTGTTTTC CGACACACTC AATACCCTGA TGTGCCCACA 
AGAAGGGAAC TTGCCGAAAA CTTAGGTGTG ACTGAAGACA AAGTGCGGGT TTGGTTTAAG 
AATAAAAGGG CCAGATGTAG GCGACATCAG AGAGAATTAA TGCTCGCCAA TGAACTACGT 
GCTGACCCAG ACGACTGTGT CTACATCGTC GTGGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Homeobox gene Rhox5 is regulated by epigenetic mechanisms in cancer and stem cells and promotes cancer growth.
Molecular cancer1063(2011 May)
Li Q,O'Malley ME,Bartlett DL,Guo ZS

Three epigenetic drugs up-regulate homeobox gene Rhox5 in cancer cells through overlapping and distinct molecular mechanisms.
Molecular pharmacology76(5)1072-81(2009 Nov)
Li Q,Bartlett DL,Gorry MC,O'Malley ME,Guo ZS

A census of human transcription factors: function, expression and evolution.
Nature reviews. Genetics10(4)252-63(2009 04)
Vaquerizas JM,Kummerfeld SK,Teichmann SA,Luscombe NM

Conservation and variation of gene regulation in embryonic stem cells assessed by comparative genomics.
Cell biochemistry and biophysics43(3)379-405(2005)
Zhan M,Miura T,Xu X,Rao MS

Two novel human X-linked homeobox genes, hPEPP1 and hPEPP2, selectively expressed in the testis.
Gene301(1-2)1-11(2002 Nov)
Wayne CM,MacLean JA,Cornwall G,Wilkinson MF