| Gene Symbol | CHIT1 |
| Entrez Gene ID | 1118 |
| Full Name | chitinase 1 |
| Synonyms | CHI3,CHIT,CHITD |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2012]. |
| Disorder MIM: | |
| Disorder Html: | [Chitotriosidase deficiency], 614122 (3) |









































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