B3GNT3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	B3GNT3
Entrez Gene ID	10331
Full Name	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
Synonyms	B3GAL-T8,B3GN-T3,B3GNT-3,HP10328,TMEM3,beta3Gn-T3
General protein information	Preferred Names UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 Names N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 8 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 8 beta-1,3-GalTase 8 beta-1,3-Gn-T3 beta-1,3-N-acetylglucosaminyltransferase bGnT-3 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase beta-3-Gx-T8 beta3GalT8 core 1 extending beta-1,3-N-acetylglucosaminyltransferase core1-beta3GlcNAcT putative type II membrane protein transmembrane protein 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19p13.11
Summary	This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein and contains a signal anchor that is not cleaved. It prefers the substrates of lacto-N-tetraose and lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains and the biosynthesis of the backbone structure of dimeric sialyl Lewis a. It plays dominant roles in L-selectin ligand biosynthesis, lymphocyte homing and lymphocyte trafficking. [provided by RefSeq, Jul 2008].
Disorder MIM:	605863

mRNA and Protein(s)

mRNA	Protein	Name
XM_011527626.2	XP_011525928.1	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 isoform X1
NM_014256.4	NP_055071.2	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3
NM_014256.3	NP_055071.2	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	B3GNT3	XP_541947.1
Danio rerio (zebrafish)	si:ch211-126g16.11	NP_001121717.1
Danio rerio (zebrafish)	b3gnt3	NP_001103580.1
	B3GNT3	XP_001113907.1
Danio rerio (zebrafish)	zgc:86586	NP_001009903.2
Homo sapiens (human)	B3GNT3	NP_055071.2
Xenopus tropicalis (tropical clawed frog)	LOC100145701	NP_001120547.1
Pan troglodytes (chimpanzee)	B3GNT3	XP_001173674.1
Bos taurus (cattle)	B3GNT3	NP_001091943.1
Mus musculus (house mouse)	B3gnt3	NP_082465.3
Rattus norvegicus (Norway rat)	B3gnt3	NP_001099538.1
Danio rerio (zebrafish)	si:ch211-126g16.10	NP_001122024.1

Gene Ontology
Bibliography

Related articles in PubMed

B3GNT3 Expression Is a Novel Marker Correlated with Pelvic Lymph Node Metastasis and Poor Clinical Outcome in Early-Stage Cervical Cancer.
Zhang W, Hou T, Niu C, Song L, Zhang Y
PloS one10(12)e0144360(2015)

A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and ? fetoprotein and their associations with cancer risk.
He M, Wu C, Xu J, Guo H, Yang H, Zhang X, Sun J, Yu D, Zhou L, Peng T, He Y, Gao Y, Yuan J, Deng Q, Dai X, Tan A, Feng Y, Zhang H, Min X, Yang X, Zhu J, Zhai K, Chang J, Qin X, Tan W, Hu Y, Lang M, Tao S, Li Y, Li Y, Feng J, Li D, Kim ST, Zhang S, Zhang H, Zheng SL, Gui L, Wang Y, Wei S, Wang F, Fang W, Liang Y, Zhai Y, Chen W, Miao X, Zhou G, Hu FB, Lin D, Mo Z, Wu T
Gut63(1)143-51(2014 Jan)

B3GNT3 expression suppresses cell migration and invasion and predicts favorable outcomes in neuroblastoma.
Ho WL, Che MI, Chou CH, Chang HH, Jeng YM, Hsu WM, Lin KH, Huang MC
Cancer science104(12)1600-8(2013 Dec)

Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.
Casabonne D, Reina O, Benavente Y, Becker N, Maynadi? M, Foretov? L, Cocco P, Gonz?lez-Neira A, Nieters A, Boffetta P, Middeldorp JM, de Sanjose S
Haematologica96(2)323-7(2011 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study demonstrated that elevated B3GNT3 expression is associated with pelvic lymph node metastasis and poor outcome in early-stage cervical cancer patients.
Title: B3GNT3 Expression Is a Novel Marker Correlated with Pelvic Lymph Node Metastasis and Poor Clinical Outcome in Early-Stage Cervical Cancer.

B3GNT3 predicts a favorable cancer behavior of neuroblastoma and suppresses malignant phenotypes by modulating mucin-type O-glycosylation and signaling in neuroblastoma cells.
Title: B3GNT3 expression suppresses cell migration and invasion and predicts favorable outcomes in neuroblastoma.

Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.

Observational study of gene-disease association. (HuGE Navigator)
Title: L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma.

The following B3GNT3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the B3GNT3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu17813	NM_014256.4 Latest version!	Homo sapiens UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 (B3GNT3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu17813	XM_011527626.2 Latest version!	Homo sapiens UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 (B3GNT3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
View Old Accession Versions >>
OHu17813	NM_014256.3	Homo sapiens UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 (B3GNT3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

B3GNT3 ( NM_014256.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055071.2 Homo sapiens UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 (B3GNT3), mRNA.

Price & Availability↑

CloneID	OHu17813
Clone ID Related Accession (Same CDS sequence)	XM_011527626.2 , NM_014256.4 , NM_014256.3
Accession Version	NM_014256.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1119bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Homo sapiens(human)
Product	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA385410.1, AB015630.1, AB049585.1, DB104034.1 and AW848963.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_014256.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB049585.1, AB015630.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000318683.7/ ENSP00000321874.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAAGTATC TCCGGCACCG GCGGCCCAAT GCCACCCTCA TTCTGGCCAT CGGCGCTTTC 
ACCCTCCTCC TCTTCAGTCT GCTAGTGTCA CCACCCACCT GCAAGGTCCA GGAGCAGCCA 
CCGGCGATCC CCGAGGCCCT GGCCTGGCCC ACTCCACCCA CCCGCCCAGC CCCGGCCCCG 
TGCCATGCCA ACACCTCTAT GGTCACCCAC CCGGACTTCG CCACGCAGCC GCAGCACGTT 
CAGAACTTCC TCCTGTACAG ACACTGCCGC CACTTTCCCC TGCTGCAGGA CGTGCCCCCC 
TCTAAGTGCG CGCAGCCGGT CTTCCTGCTG CTGGTGATCA AGTCCTCCCC TAGCAACTAT 
GTGCGCCGCG AGCTGCTGCG GCGCACGTGG GGCCGCGAGC GCAAGGTACG GGGTTTGCAG 
CTGCGCCTCC TCTTCCTGGT GGGCACAGCC TCCAACCCGC ACGAGGCCCG CAAGGTCAAC 
CGGCTGCTGG AGCTGGAGGC ACAGACTCAC GGAGACATCC TGCAGTGGGA CTTCCACGAC 
TCCTTCTTCA ACCTCACGCT CAAGCAGGTC CTGTTCTTAC AGTGGCAGGA GACAAGGTGC 
GCCAACGCCA GCTTCGTGCT CAACGGGGAT GATGACGTCT TTGCACACAC AGACAACATG 
GTCTTCTACC TGCAGGACCA TGACCCTGGC CGCCACCTCT TCGTGGGGCA ACTGATCCAA 
AACGTGGGCC CCATCCGGGC TTTTTGGAGC AAGTACTATG TGCCAGAGGT GGTGACTCAG 
AATGAGCGGT ACCCACCCTA TTGTGGGGGT GGTGGCTTCT TGCTGTCCCG CTTCACGGCC 
GCTGCCCTGC GCCGTGCTGC CCATGTCTTG GACATCTTCC CCATTGATGA TGTCTTCCTG 
GGTATGTGTC TGGAGCTTGA GGGACTGAAG CCTGCCTCCC ACAGCGGCAT CCGCACGTCT 
GGCGTGCGGG CTCCATCGCA ACGCCTGTCC TCCTTTGACC CCTGCTTCTA CCGAGACCTG 
CTGCTGGTGC ACCGCTTCCT ACCTTATGAG ATGCTGCTCA TGTGGGATGC GCTGAACCAG 
CCCAACCTCA CCTGCGGCAA TCAGACACAG ATCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055071.2
CDS	120..1238
Translation	MKYLRHRRPNATLILAIGAFTLLLFSLLVSPPTCKVQEQPPAIPEALAWPTPPTRPAPAPCHANTSMVTHPDFATQPQHVQNFLLYRHCRHFPLLQDVPPSKCAQPVFLLLVIKSSPSNYVRRELLRRTWGRERKVRGLQLRLLFLVGTASNPHEARKVNRLLELEAQTHGDILQWDFHDSFFNLTLKQVLFLQWQETRCANASFVLNGDDDVFAHTDNMVFYLQDHDPGRHLFVGQLIQNVGPIRAFWSKYYVPEVVTQNERYPPYCGGGGFLLSRFTAAALRRAAHVLDIFPIDDVFLGMCLELEGLKPASHSGIRTSGVRAPSQRLSSFDPCFYRDLLLVHRFLPYEMLLMWDALNQPNLTCGNQTQIY

Target ORF information:

RefSeq Version	NM_014256.4
Organism	Homo sapiens(human)
Definition	Homo sapiens UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 (B3GNT3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014256.4

ORF Insert Sequence:

ATGAAGTATC TCCGGCACCG GCGGCCCAAT GCCACCCTCA TTCTGGCCAT CGGCGCTTTC 
ACCCTCCTCC TCTTCAGTCT GCTAGTGTCA CCACCCACCT GCAAGGTCCA GGAGCAGCCA 
CCGGCGATCC CCGAGGCCCT GGCCTGGCCC ACTCCACCCA CCCGCCCAGC CCCGGCCCCG 
TGCCATGCCA ACACCTCTAT GGTCACCCAC CCGGACTTCG CCACGCAGCC GCAGCACGTT 
CAGAACTTCC TCCTGTACAG ACACTGCCGC CACTTTCCCC TGCTGCAGGA CGTGCCCCCC 
TCTAAGTGCG CGCAGCCGGT CTTCCTGCTG CTGGTGATCA AGTCCTCCCC TAGCAACTAT 
GTGCGCCGCG AGCTGCTGCG GCGCACGTGG GGCCGCGAGC GCAAGGTACG GGGTTTGCAG 
CTGCGCCTCC TCTTCCTGGT GGGCACAGCC TCCAACCCGC ACGAGGCCCG CAAGGTCAAC 
CGGCTGCTGG AGCTGGAGGC ACAGACTCAC GGAGACATCC TGCAGTGGGA CTTCCACGAC 
TCCTTCTTCA ACCTCACGCT CAAGCAGGTC CTGTTCTTAC AGTGGCAGGA GACAAGGTGC 
GCCAACGCCA GCTTCGTGCT CAACGGGGAT GATGACGTCT TTGCACACAC AGACAACATG 
GTCTTCTACC TGCAGGACCA TGACCCTGGC CGCCACCTCT TCGTGGGGCA ACTGATCCAA 
AACGTGGGCC CCATCCGGGC TTTTTGGAGC AAGTACTATG TGCCAGAGGT GGTGACTCAG 
AATGAGCGGT ACCCACCCTA TTGTGGGGGT GGTGGCTTCT TGCTGTCCCG CTTCACGGCC 
GCTGCCCTGC GCCGTGCTGC CCATGTCTTG GACATCTTCC CCATTGATGA TGTCTTCCTG 
GGTATGTGTC TGGAGCTTGA GGGACTGAAG CCTGCCTCCC ACAGCGGCAT CCGCACGTCT 
GGCGTGCGGG CTCCATCGCA ACGCCTGTCC TCCTTTGACC CCTGCTTCTA CCGAGACCTG 
CTGCTGGTGC ACCGCTTCCT ACCTTATGAG ATGCTGCTCA TGTGGGATGC GCTGAACCAG 
CCCAACCTCA CCTGCGGCAA TCAGACACAG ATCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

B3GNT3 ( NM_014256.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055071.2 Homo sapiens UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 (B3GNT3), mRNA.

Price & Availability↑

CloneID	OHu17813
Clone ID Related Accession (Same CDS sequence)	XM_011527626.2 , NM_014256.4 , NM_014256.3
Accession Version	NM_014256.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1119bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA385410.1, AB015630.1, AB049585.1, DB104034.1 and AW848963.1. This sequence is a reference standard in the RefSeqGene project. On Apr 14, 2006 this sequence version replaced NM_014256.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK075466.1, AB015630.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGTATC TCCGGCACCG GCGGCCCAAT GCCACCCTCA TTCTGGCCAT CGGCGCTTTC 
ACCCTCCTCC TCTTCAGTCT GCTAGTGTCA CCACCCACCT GCAAGGTCCA GGAGCAGCCA 
CCGGCGATCC CCGAGGCCCT GGCCTGGCCC ACTCCACCCA CCCGCCCAGC CCCGGCCCCG 
TGCCATGCCA ACACCTCTAT GGTCACCCAC CCGGACTTCG CCACGCAGCC GCAGCACGTT 
CAGAACTTCC TCCTGTACAG ACACTGCCGC CACTTTCCCC TGCTGCAGGA CGTGCCCCCC 
TCTAAGTGCG CGCAGCCGGT CTTCCTGCTG CTGGTGATCA AGTCCTCCCC TAGCAACTAT 
GTGCGCCGCG AGCTGCTGCG GCGCACGTGG GGCCGCGAGC GCAAGGTACG GGGTTTGCAG 
CTGCGCCTCC TCTTCCTGGT GGGCACAGCC TCCAACCCGC ACGAGGCCCG CAAGGTCAAC 
CGGCTGCTGG AGCTGGAGGC ACAGACTCAC GGAGACATCC TGCAGTGGGA CTTCCACGAC 
TCCTTCTTCA ACCTCACGCT CAAGCAGGTC CTGTTCTTAC AGTGGCAGGA GACAAGGTGC 
GCCAACGCCA GCTTCGTGCT CAACGGGGAT GATGACGTCT TTGCACACAC AGACAACATG 
GTCTTCTACC TGCAGGACCA TGACCCTGGC CGCCACCTCT TCGTGGGGCA ACTGATCCAA 
AACGTGGGCC CCATCCGGGC TTTTTGGAGC AAGTACTATG TGCCAGAGGT GGTGACTCAG 
AATGAGCGGT ACCCACCCTA TTGTGGGGGT GGTGGCTTCT TGCTGTCCCG CTTCACGGCC 
GCTGCCCTGC GCCGTGCTGC CCATGTCTTG GACATCTTCC CCATTGATGA TGTCTTCCTG 
GGTATGTGTC TGGAGCTTGA GGGACTGAAG CCTGCCTCCC ACAGCGGCAT CCGCACGTCT 
GGCGTGCGGG CTCCATCGCA ACGCCTGTCC TCCTTTGACC CCTGCTTCTA CCGAGACCTG 
CTGCTGGTGC ACCGCTTCCT ACCTTATGAG ATGCTGCTCA TGTGGGATGC GCTGAACCAG 
CCCAACCTCA CCTGCGGCAA TCAGACACAG ATCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055071.2
CDS	148..1266
Translation	MKYLRHRRPNATLILAIGAFTLLLFSLLVSPPTCKVQEQPPAIPEALAWPTPPTRPAPAPCHANTSMVTHPDFATQPQHVQNFLLYRHCRHFPLLQDVPPSKCAQPVFLLLVIKSSPSNYVRRELLRRTWGRERKVRGLQLRLLFLVGTASNPHEARKVNRLLELEAQTHGDILQWDFHDSFFNLTLKQVLFLQWQETRCANASFVLNGDDDVFAHTDNMVFYLQDHDPGRHLFVGQLIQNVGPIRAFWSKYYVPEVVTQNERYPPYCGGGGFLLSRFTAAALRRAAHVLDIFPIDDVFLGMCLELEGLKPASHSGIRTSGVRAPSQRLSSFDPCFYRDLLLVHRFLPYEMLLMWDALNQPNLTCGNQTQIY

Target ORF information:

RefSeq Version	NM_014256.3
Organism	Homo sapiens(human)
Definition	Homo sapiens UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 (B3GNT3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014256.3

ORF Insert Sequence:

ATGAAGTATC TCCGGCACCG GCGGCCCAAT GCCACCCTCA TTCTGGCCAT CGGCGCTTTC 
ACCCTCCTCC TCTTCAGTCT GCTAGTGTCA CCACCCACCT GCAAGGTCCA GGAGCAGCCA 
CCGGCGATCC CCGAGGCCCT GGCCTGGCCC ACTCCACCCA CCCGCCCAGC CCCGGCCCCG 
TGCCATGCCA ACACCTCTAT GGTCACCCAC CCGGACTTCG CCACGCAGCC GCAGCACGTT 
CAGAACTTCC TCCTGTACAG ACACTGCCGC CACTTTCCCC TGCTGCAGGA CGTGCCCCCC 
TCTAAGTGCG CGCAGCCGGT CTTCCTGCTG CTGGTGATCA AGTCCTCCCC TAGCAACTAT 
GTGCGCCGCG AGCTGCTGCG GCGCACGTGG GGCCGCGAGC GCAAGGTACG GGGTTTGCAG 
CTGCGCCTCC TCTTCCTGGT GGGCACAGCC TCCAACCCGC ACGAGGCCCG CAAGGTCAAC 
CGGCTGCTGG AGCTGGAGGC ACAGACTCAC GGAGACATCC TGCAGTGGGA CTTCCACGAC 
TCCTTCTTCA ACCTCACGCT CAAGCAGGTC CTGTTCTTAC AGTGGCAGGA GACAAGGTGC 
GCCAACGCCA GCTTCGTGCT CAACGGGGAT GATGACGTCT TTGCACACAC AGACAACATG 
GTCTTCTACC TGCAGGACCA TGACCCTGGC CGCCACCTCT TCGTGGGGCA ACTGATCCAA 
AACGTGGGCC CCATCCGGGC TTTTTGGAGC AAGTACTATG TGCCAGAGGT GGTGACTCAG 
AATGAGCGGT ACCCACCCTA TTGTGGGGGT GGTGGCTTCT TGCTGTCCCG CTTCACGGCC 
GCTGCCCTGC GCCGTGCTGC CCATGTCTTG GACATCTTCC CCATTGATGA TGTCTTCCTG 
GGTATGTGTC TGGAGCTTGA GGGACTGAAG CCTGCCTCCC ACAGCGGCAT CCGCACGTCT 
GGCGTGCGGG CTCCATCGCA ACGCCTGTCC TCCTTTGACC CCTGCTTCTA CCGAGACCTG 
CTGCTGGTGC ACCGCTTCCT ACCTTATGAG ATGCTGCTCA TGTGGGATGC GCTGAACCAG 
CCCAACCTCA CCTGCGGCAA TCAGACACAG ATCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

B3GNT3 ( XM_011527626.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011525928.1 Homo sapiens UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 (B3GNT3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu17813
Clone ID Related Accession (Same CDS sequence)	XM_011527626.2 , NM_014256.4 , NM_014256.3
Accession Version	XM_011527626.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1119bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011527626.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGTATC TCCGGCACCG GCGGCCCAAT GCCACCCTCA TTCTGGCCAT CGGCGCTTTC 
ACCCTCCTCC TCTTCAGTCT GCTAGTGTCA CCACCCACCT GCAAGGTCCA GGAGCAGCCA 
CCGGCGATCC CCGAGGCCCT GGCCTGGCCC ACTCCACCCA CCCGCCCAGC CCCGGCCCCG 
TGCCATGCCA ACACCTCTAT GGTCACCCAC CCGGACTTCG CCACGCAGCC GCAGCACGTT 
CAGAACTTCC TCCTGTACAG ACACTGCCGC CACTTTCCCC TGCTGCAGGA CGTGCCCCCC 
TCTAAGTGCG CGCAGCCGGT CTTCCTGCTG CTGGTGATCA AGTCCTCCCC TAGCAACTAT 
GTGCGCCGCG AGCTGCTGCG GCGCACGTGG GGCCGCGAGC GCAAGGTACG GGGTTTGCAG 
CTGCGCCTCC TCTTCCTGGT GGGCACAGCC TCCAACCCGC ACGAGGCCCG CAAGGTCAAC 
CGGCTGCTGG AGCTGGAGGC ACAGACTCAC GGAGACATCC TGCAGTGGGA CTTCCACGAC 
TCCTTCTTCA ACCTCACGCT CAAGCAGGTC CTGTTCTTAC AGTGGCAGGA GACAAGGTGC 
GCCAACGCCA GCTTCGTGCT CAACGGGGAT GATGACGTCT TTGCACACAC AGACAACATG 
GTCTTCTACC TGCAGGACCA TGACCCTGGC CGCCACCTCT TCGTGGGGCA ACTGATCCAA 
AACGTGGGCC CCATCCGGGC TTTTTGGAGC AAGTACTATG TGCCAGAGGT GGTGACTCAG 
AATGAGCGGT ACCCACCCTA TTGTGGGGGT GGTGGCTTCT TGCTGTCCCG CTTCACGGCC 
GCTGCCCTGC GCCGTGCTGC CCATGTCTTG GACATCTTCC CCATTGATGA TGTCTTCCTG 
GGTATGTGTC TGGAGCTTGA GGGACTGAAG CCTGCCTCCC ACAGCGGCAT CCGCACGTCT 
GGCGTGCGGG CTCCATCGCA ACGCCTGTCC TCCTTTGACC CCTGCTTCTA CCGAGACCTG 
CTGCTGGTGC ACCGCTTCCT ACCTTATGAG ATGCTGCTCA TGTGGGATGC GCTGAACCAG 
CCCAACCTCA CCTGCGGCAA TCAGACACAG ATCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011525928.1
CDS	107..1225
Translation	MKYLRHRRPNATLILAIGAFTLLLFSLLVSPPTCKVQEQPPAIPEALAWPTPPTRPAPAPCHANTSMVTHPDFATQPQHVQNFLLYRHCRHFPLLQDVPPSKCAQPVFLLLVIKSSPSNYVRRELLRRTWGRERKVRGLQLRLLFLVGTASNPHEARKVNRLLELEAQTHGDILQWDFHDSFFNLTLKQVLFLQWQETRCANASFVLNGDDDVFAHTDNMVFYLQDHDPGRHLFVGQLIQNVGPIRAFWSKYYVPEVVTQNERYPPYCGGGGFLLSRFTAAALRRAAHVLDIFPIDDVFLGMCLELEGLKPASHSGIRTSGVRAPSQRLSSFDPCFYRDLLLVHRFLPYEMLLMWDALNQPNLTCGNQTQIY

Target ORF information:

RefSeq Version	XM_011527626.2
Organism	Homo sapiens(human)
Definition	Homo sapiens UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 (B3GNT3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011527626.2

ORF Insert Sequence:

ATGAAGTATC TCCGGCACCG GCGGCCCAAT GCCACCCTCA TTCTGGCCAT CGGCGCTTTC 
ACCCTCCTCC TCTTCAGTCT GCTAGTGTCA CCACCCACCT GCAAGGTCCA GGAGCAGCCA 
CCGGCGATCC CCGAGGCCCT GGCCTGGCCC ACTCCACCCA CCCGCCCAGC CCCGGCCCCG 
TGCCATGCCA ACACCTCTAT GGTCACCCAC CCGGACTTCG CCACGCAGCC GCAGCACGTT 
CAGAACTTCC TCCTGTACAG ACACTGCCGC CACTTTCCCC TGCTGCAGGA CGTGCCCCCC 
TCTAAGTGCG CGCAGCCGGT CTTCCTGCTG CTGGTGATCA AGTCCTCCCC TAGCAACTAT 
GTGCGCCGCG AGCTGCTGCG GCGCACGTGG GGCCGCGAGC GCAAGGTACG GGGTTTGCAG 
CTGCGCCTCC TCTTCCTGGT GGGCACAGCC TCCAACCCGC ACGAGGCCCG CAAGGTCAAC 
CGGCTGCTGG AGCTGGAGGC ACAGACTCAC GGAGACATCC TGCAGTGGGA CTTCCACGAC 
TCCTTCTTCA ACCTCACGCT CAAGCAGGTC CTGTTCTTAC AGTGGCAGGA GACAAGGTGC 
GCCAACGCCA GCTTCGTGCT CAACGGGGAT GATGACGTCT TTGCACACAC AGACAACATG 
GTCTTCTACC TGCAGGACCA TGACCCTGGC CGCCACCTCT TCGTGGGGCA ACTGATCCAA 
AACGTGGGCC CCATCCGGGC TTTTTGGAGC AAGTACTATG TGCCAGAGGT GGTGACTCAG 
AATGAGCGGT ACCCACCCTA TTGTGGGGGT GGTGGCTTCT TGCTGTCCCG CTTCACGGCC 
GCTGCCCTGC GCCGTGCTGC CCATGTCTTG GACATCTTCC CCATTGATGA TGTCTTCCTG 
GGTATGTGTC TGGAGCTTGA GGGACTGAAG CCTGCCTCCC ACAGCGGCAT CCGCACGTCT 
GGCGTGCGGG CTCCATCGCA ACGCCTGTCC TCCTTTGACC CCTGCTTCTA CCGAGACCTG 
CTGCTGGTGC ACCGCTTCCT ACCTTATGAG ATGCTGCTCA TGTGGGATGC GCTGAACCAG 
CCCAACCTCA CCTGCGGCAA TCAGACACAG ATCTACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

B3GNT3 Expression Is a Novel Marker Correlated with Pelvic Lymph Node Metastasis and Poor Clinical Outcome in Early-Stage Cervical Cancer.
PloS one10(12)e0144360(2015)
Zhang W,Hou T,Niu C,Song L,Zhang Y

A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and ? fetoprotein and their associations with cancer risk.
Gut63(1)143-51(2014 Jan)
He M,Wu C,Xu J,Guo H,Yang H,Zhang X,Sun J,Yu D,Zhou L,Peng T,He Y,Gao Y,Yuan J,Deng Q,Dai X,Tan A,Feng Y,Zhang H,Min X,Yang X,Zhu J,Zhai K,Chang J,Qin X,Tan W,Hu Y,Lang M,Tao S,Li Y,Li Y,Feng J,Li D,Kim ST,Zhang S,Zhang H,Zheng SL,Gui L,Wang Y,Wei S,Wang F,Fang W,Liang Y,Zhai Y,Chen W,Miao X,Zhou G,Hu FB,Lin D,Mo Z,Wu T

B3GNT3 expression suppresses cell migration and invasion and predicts favorable outcomes in neuroblastoma.
Cancer science104(12)1600-8(2013 Dec)
Ho WL,Che MI,Chou CH,Chang HH,Jeng YM,Hsu WM,Lin KH,Huang MC

Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.
Haematologica96(2)323-7(2011 Feb)
Casabonne D,Reina O,Benavente Y,Becker N,Maynadi? M,Foretov? L,Cocco P,Gonz?lez-Neira A,Nieters A,Boffetta P,Middeldorp JM,de Sanjose S