RXYLT1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RXYLT1
Entrez Gene ID	10329
Full Name	ribitol xylosyltransferase 1
Synonyms	HP10481,MDDGA10,TMEM5
General protein information	Preferred Names ribitol xylosyltransferase 1 Names UDP-D-xylose:ribitol-5-phosphate beta1,4-xylosyltransferase transmembrane protein 5 type II membrane protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 12 Map Location: 12q14.2
Summary	This gene encodes a type II transmembrane protein that is thought to have glycosyltransferase function. Mutations in this gene result in cobblestone lissencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013].
Disorder MIM:	605862
Disorder Html:	Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 10, 615041 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_017018686.1	XP_016874175.1	ribitol-5-phosphate xylosyltransferase 1 isoform X2
XM_017018687.1	XP_016874176.1	ribitol-5-phosphate xylosyltransferase 1 isoform X2
NM_014254.3	NP_055069.1	ribitol-5-phosphate xylosyltransferase 1 isoform 1
NM_001278237.1	NP_001265166.1	ribitol-5-phosphate xylosyltransferase 1 isoform 2
NM_014254.2	NP_055069.1	ribitol-5-phosphate xylosyltransferase 1 isoform 1
XM_005268563.3	XP_005268620.1	ribitol-5-phosphate xylosyltransferase 1 isoform X1
XM_005268562.3	XP_005268619.1	ribitol-5-phosphate xylosyltransferase 1 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Tmem5	NP_001019930.1
Danio rerio (zebrafish)	tmem5	NP_001068580.1
Pan troglodytes (chimpanzee)	TMEM5	XP_509188.2
Gallus gallus (chicken)	TMEM5	NP_001186486.1
Homo sapiens (human)	TMEM5	NP_055069.1
	TMEM5	XP_001116803.1
Bos taurus (cattle)	TMEM5	NP_001033203.1
Mus musculus (house mouse)	Tmem5	NP_694699.1
Xenopus tropicalis (tropical clawed frog)	tmem5	NP_001120448.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

The Muscular Dystrophy Gene TMEM5 Encodes a Ribitol ?1,4-Xylosyltransferase Required for the Functional Glycosylation of Dystroglycan.
Manya H, Yamaguchi Y, Kanagawa M, Kobayashi K, Tajiri M, Akasaka-Manya K, Kawakami H, Mizuno M, Wada Y, Toda T, Endo T
The Journal of biological chemistry291(47)24618-24627(2016 Nov)

The functional O-mannose glycan on ?-dystroglycan contains a phospho-ribitol primed for matriglycan addition.
Praissman JL, Willer T, Sheikh MO, Toi A, Chitayat D, Lin YY, Lee H, Stalnaker SH, Wang S, Prabhakar PK, Nelson SF, Stemple DL, Moore SA, Moremen KW, Campbell KP, Wells L
eLife5(2016 04)

The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated ?-dystroglycan functional glycosylation.
Willer T, Inamori K, Venzke D, Harvey C, Morgensen G, Hara Y, Beltr?n Valero de Bernab? D, Yu L, Wright KM, Campbell KP
eLife3(2014 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

TMEM5 acts as a UDP-d-xylose:ribitol-5-phosphate beta1,4-xylosyltransferase in the biosynthetic pathway of O-mannosyl glycan.
Title: The Muscular Dystrophy Gene TMEM5 Encodes a Ribitol ?1,4-Xylosyltransferase Required for the Functional Glycosylation of Dystroglycan.

TMEM5 is a UDP-xylosyl transferase that elaborates the O-mannose glycan structure on alpha-dystroglycan. The authors demonstrate in a zebrafish model as well as in a human patient that defects in TMEM5 result in muscular dystrophy in combination with abnormal brain development.
Title: The functional O-mannose glycan on ?-dystroglycan contains a phospho-ribitol primed for matriglycan addition.

TMEM5 mutations were frequently associated with gonadal dysgenesis and neural tube defects, and ISPD mutations were frequently associated with brain vascular anomalies.
Title: Identification of mutations in TMEM5 and ISPD as a cause of severe cobblestone lissencephaly.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

The following RXYLT1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RXYLT1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu04381	NM_001278237.1 Latest version!	Homo sapiens ribitol xylosyltransferase 1 (RXYLT1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu04381	XM_017018687.1 Latest version!	Homo sapiens ribitol xylosyltransferase 1 (RXYLT1), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu04381	XM_017018686.1 Latest version!	Homo sapiens ribitol xylosyltransferase 1 (RXYLT1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu46251	XM_005268563.3 Latest version!	Homo sapiens ribitol xylosyltransferase 1 (RXYLT1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu46251	XM_005268562.3 Latest version!	Homo sapiens ribitol xylosyltransferase 1 (RXYLT1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OHu21422	NM_014254.3 Latest version!	Homo sapiens ribitol xylosyltransferase 1 (RXYLT1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
View Old Accession Versions >>
OHu21422	NM_014254.2	Homo sapiens ribitol xylosyltransferase 1 (RXYLT1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RXYLT1 ( NM_001278237.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001265166.1 Homo sapiens ribitol xylosyltransferase 1 (RXYLT1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu04381
Clone ID Related Accession (Same CDS sequence)	XM_017018686.1 , XM_017018687.1 , NM_001278237.1
Accession Version	NM_001278237.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 552bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	ribitol-5-phosphate xylosyltransferase 1 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM547839.1, BX647419.1 and BC013152.1. Transcript Variant: This variant (2) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (2) with a shorter N-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: BX647105.1, SRR1660807.151738.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGCTGCATG ATGAGAGGCC ATATTTATGT AATTTCTTAG GAACGATTTA TGAAAATTCA 
TCCAGACAGG CACTAATGAA CATTTTGAAA AAAGATGGGA ACGATAAGCT TTGTTGGGTT 
TCAGCAAGAG AACACTGGCA GCCTCAGGAA ACAAATGAAA GTCTTAAGAA TTACCAAGAT 
GCCTTGCTTC AGAGTGATCT CACATTGTGC CCGGTCGGAG TAAACACAGA ATGCTATCGA 
ATCTATGAGG CTTGCTCCTA TGGCTCCATT CCTGTGGTGG AAGACGTGAT GACAGCTGGC 
AACTGTGGGA ATACATCTGT GCACCACGGT GCTCCTCTGC AGTTACTCAA GTCCATGGGT 
GCTCCCTTTA TCTTTATCAA GAACTGGAAG GAACTCCCTG CTGTTTTAGA AAAAGAGAAA 
ACTATAATTT TACAAGAAAA AATTGAAAGA AGAAAAATGT TACTTCAGTG GTATCAGCAC 
TTCAAGACAG AGCTTAAAAT GAAATTTACT AATATTTTAG AAAGCTCATT TTTAATGAAT 
AATAAAAGTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001265166.1
CDS	949..1500
Translation	MLHDERPYLCNFLGTIYENSSRQALMNILKKDGNDKLCWVSAREHWQPQETNESLKNYQDALLQSDLTLCPVGVNTECYRIYEACSYGSIPVVEDVMTAGNCGNTSVHHGAPLQLLKSMGAPFIFIKNWKELPAVLEKEKTIILQEKIERRKMLLQWYQHFKTELKMKFTNILESSFLMNNKS

Target ORF information:

RefSeq Version	NM_001278237.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ribitol xylosyltransferase 1 (RXYLT1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001278237.1

ORF Insert Sequence:

ATGCTGCATG ATGAGAGGCC ATATTTATGT AATTTCTTAG GAACGATTTA TGAAAATTCA 
TCCAGACAGG CACTAATGAA CATTTTGAAA AAAGATGGGA ACGATAAGCT TTGTTGGGTT 
TCAGCAAGAG AACACTGGCA GCCTCAGGAA ACAAATGAAA GTCTTAAGAA TTACCAAGAT 
GCCTTGCTTC AGAGTGATCT CACATTGTGC CCGGTCGGAG TAAACACAGA ATGCTATCGA 
ATCTATGAGG CTTGCTCCTA TGGCTCCATT CCTGTGGTGG AAGACGTGAT GACAGCTGGC 
AACTGTGGGA ATACATCTGT GCACCACGGT GCTCCTCTGC AGTTACTCAA GTCCATGGGT 
GCTCCCTTTA TCTTTATCAA GAACTGGAAG GAACTCCCTG CTGTTTTAGA AAAAGAGAAA 
ACTATAATTT TACAAGAAAA AATTGAAAGA AGAAAAATGT TACTTCAGTG GTATCAGCAC 
TTCAAGACAG AGCTTAAAAT GAAATTTACT AATATTTTAG AAAGCTCATT TTTAATGAAT 
AATAAAAGTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RXYLT1 ( XM_017018686.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016874175.1 Homo sapiens ribitol xylosyltransferase 1 (RXYLT1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu04381
Clone ID Related Accession (Same CDS sequence)	XM_017018686.1 , XM_017018687.1 , NM_001278237.1
Accession Version	XM_017018686.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 552bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ribitol-5-phosphate xylosyltransferase 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGCATG ATGAGAGGCC ATATTTATGT AATTTCTTAG GAACGATTTA TGAAAATTCA 
TCCAGACAGG CACTAATGAA CATTTTGAAA AAAGATGGGA ACGATAAGCT TTGTTGGGTT 
TCAGCAAGAG AACACTGGCA GCCTCAGGAA ACAAATGAAA GTCTTAAGAA TTACCAAGAT 
GCCTTGCTTC AGAGTGATCT CACATTGTGC CCGGTCGGAG TAAACACAGA ATGCTATCGA 
ATCTATGAGG CTTGCTCCTA TGGCTCCATT CCTGTGGTGG AAGACGTGAT GACAGCTGGC 
AACTGTGGGA ATACATCTGT GCACCACGGT GCTCCTCTGC AGTTACTCAA GTCCATGGGT 
GCTCCCTTTA TCTTTATCAA GAACTGGAAG GAACTCCCTG CTGTTTTAGA AAAAGAGAAA 
ACTATAATTT TACAAGAAAA AATTGAAAGA AGAAAAATGT TACTTCAGTG GTATCAGCAC 
TTCAAGACAG AGCTTAAAAT GAAATTTACT AATATTTTAG AAAGCTCATT TTTAATGAAT 
AATAAAAGTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016874175.1
CDS	1004..1555
Translation	MLHDERPYLCNFLGTIYENSSRQALMNILKKDGNDKLCWVSAREHWQPQETNESLKNYQDALLQSDLTLCPVGVNTECYRIYEACSYGSIPVVEDVMTAGNCGNTSVHHGAPLQLLKSMGAPFIFIKNWKELPAVLEKEKTIILQEKIERRKMLLQWYQHFKTELKMKFTNILESSFLMNNKS

Target ORF information:

RefSeq Version	XM_017018686.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ribitol xylosyltransferase 1 (RXYLT1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017018686.1

ORF Insert Sequence:

ATGCTGCATG ATGAGAGGCC ATATTTATGT AATTTCTTAG GAACGATTTA TGAAAATTCA 
TCCAGACAGG CACTAATGAA CATTTTGAAA AAAGATGGGA ACGATAAGCT TTGTTGGGTT 
TCAGCAAGAG AACACTGGCA GCCTCAGGAA ACAAATGAAA GTCTTAAGAA TTACCAAGAT 
GCCTTGCTTC AGAGTGATCT CACATTGTGC CCGGTCGGAG TAAACACAGA ATGCTATCGA 
ATCTATGAGG CTTGCTCCTA TGGCTCCATT CCTGTGGTGG AAGACGTGAT GACAGCTGGC 
AACTGTGGGA ATACATCTGT GCACCACGGT GCTCCTCTGC AGTTACTCAA GTCCATGGGT 
GCTCCCTTTA TCTTTATCAA GAACTGGAAG GAACTCCCTG CTGTTTTAGA AAAAGAGAAA 
ACTATAATTT TACAAGAAAA AATTGAAAGA AGAAAAATGT TACTTCAGTG GTATCAGCAC 
TTCAAGACAG AGCTTAAAAT GAAATTTACT AATATTTTAG AAAGCTCATT TTTAATGAAT 
AATAAAAGTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RXYLT1 ( XM_017018687.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016874176.1 Homo sapiens ribitol xylosyltransferase 1 (RXYLT1), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu04381
Clone ID Related Accession (Same CDS sequence)	XM_017018686.1 , XM_017018687.1 , NM_001278237.1
Accession Version	XM_017018687.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 552bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ribitol-5-phosphate xylosyltransferase 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTGCATG ATGAGAGGCC ATATTTATGT AATTTCTTAG GAACGATTTA TGAAAATTCA 
TCCAGACAGG CACTAATGAA CATTTTGAAA AAAGATGGGA ACGATAAGCT TTGTTGGGTT 
TCAGCAAGAG AACACTGGCA GCCTCAGGAA ACAAATGAAA GTCTTAAGAA TTACCAAGAT 
GCCTTGCTTC AGAGTGATCT CACATTGTGC CCGGTCGGAG TAAACACAGA ATGCTATCGA 
ATCTATGAGG CTTGCTCCTA TGGCTCCATT CCTGTGGTGG AAGACGTGAT GACAGCTGGC 
AACTGTGGGA ATACATCTGT GCACCACGGT GCTCCTCTGC AGTTACTCAA GTCCATGGGT 
GCTCCCTTTA TCTTTATCAA GAACTGGAAG GAACTCCCTG CTGTTTTAGA AAAAGAGAAA 
ACTATAATTT TACAAGAAAA AATTGAAAGA AGAAAAATGT TACTTCAGTG GTATCAGCAC 
TTCAAGACAG AGCTTAAAAT GAAATTTACT AATATTTTAG AAAGCTCATT TTTAATGAAT 
AATAAAAGTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016874176.1
CDS	1166..1717
Translation	MLHDERPYLCNFLGTIYENSSRQALMNILKKDGNDKLCWVSAREHWQPQETNESLKNYQDALLQSDLTLCPVGVNTECYRIYEACSYGSIPVVEDVMTAGNCGNTSVHHGAPLQLLKSMGAPFIFIKNWKELPAVLEKEKTIILQEKIERRKMLLQWYQHFKTELKMKFTNILESSFLMNNKS

Target ORF information:

RefSeq Version	XM_017018687.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ribitol xylosyltransferase 1 (RXYLT1), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017018687.1

ORF Insert Sequence:

ATGCTGCATG ATGAGAGGCC ATATTTATGT AATTTCTTAG GAACGATTTA TGAAAATTCA 
TCCAGACAGG CACTAATGAA CATTTTGAAA AAAGATGGGA ACGATAAGCT TTGTTGGGTT 
TCAGCAAGAG AACACTGGCA GCCTCAGGAA ACAAATGAAA GTCTTAAGAA TTACCAAGAT 
GCCTTGCTTC AGAGTGATCT CACATTGTGC CCGGTCGGAG TAAACACAGA ATGCTATCGA 
ATCTATGAGG CTTGCTCCTA TGGCTCCATT CCTGTGGTGG AAGACGTGAT GACAGCTGGC 
AACTGTGGGA ATACATCTGT GCACCACGGT GCTCCTCTGC AGTTACTCAA GTCCATGGGT 
GCTCCCTTTA TCTTTATCAA GAACTGGAAG GAACTCCCTG CTGTTTTAGA AAAAGAGAAA 
ACTATAATTT TACAAGAAAA AATTGAAAGA AGAAAAATGT TACTTCAGTG GTATCAGCAC 
TTCAAGACAG AGCTTAAAAT GAAATTTACT AATATTTTAG AAAGCTCATT TTTAATGAAT 
AATAAAAGTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RXYLT1 ( XM_005268563.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005268620.1 Homo sapiens ribitol xylosyltransferase 1 (RXYLT1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu46251
Clone ID Related Accession (Same CDS sequence)	XM_005268563.3 , XM_005268562.3
Accession Version	XM_005268563.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1023bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ribitol-5-phosphate xylosyltransferase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005268563.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGAGG AGACCTGCTT GTATCTCTGG GAGCATATTT TTGAAGGCTT ACTTGATCCC 
AGCGATGTGA CTGCTCAATG GAGAGAAGGA AAGTCAATCG TAGGAAGAAC ACAGTACAGC 
TTCATCACTG GTCCAGCTGT AATACCAGGG TACTTCTCCG TTGATGTGAA TAATGTGGTA 
CTCATTTTAA ATGGAAGAGA AAAAGCAAAG ATCTTTTATG CCACCCAGTG GTTACTTTAT 
GCACAAAATT TAGTGCAAAT TCAAAAACTC CAGCATCTTG CTGTTGTTTT GCTCGGAAAT 
GAACATTGTG ATAATGAGTG GATAAACCCA TTCCTCAAAA GAAATGGAGG CTTCGTGGAG 
CTGCTTTTCA TAATATATGA CAGCCCCTGG ATTAATGACG TGGATGTTTT TCAGTGGCCT 
TTAGGAGTAG CAACATACAG GAATTTTCCT GTGGTGGAGG CAAGTTGGTC AATGCTGCAT 
GATGAGAGGC CATATTTATG TAATTTCTTA GGAACGATTT ATGAAAATTC ATCCAGACAG 
GCACTAATGA ACATTTTGAA AAAAGATGGG AACGATAAGC TTTGTTGGGT TTCAGCAAGA 
GAACACTGGC AGCCTCAGGA AACAAATGAA AGTCTTAAGA ATTACCAAGA TGCCTTGCTT 
CAGAGTGATC TCACATTGTG CCCGGTCGGA GTAAACACAG AATGCTATCG AATCTATGAG 
GCTTGCTCCT ATGGCTCCAT TCCTGTGGTG GAAGACGTGA TGACAGCTGG CAACTGTGGG 
AATACATCTG TGCACCACGG TGCTCCTCTG CAGTTACTCA AGTCCATGGG TGCTCCCTTT 
ATCTTTATCA AGAACTGGAA GGAACTCCCT GCTGTTTTAG AAAAAGAGAA AACTATAATT 
TTACAAGAAA AAATTGAAAG AAGAAAAATG TTACTTCAGT GGTATCAGCA CTTCAAGACA 
GAGCTTAAAA TGAAATTTAC TAATATTTTA GAAAGCTCAT TTTTAATGAA TAATAAAAGT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005268620.1
CDS	651..1673
Translation	MAEETCLYLWEHIFEGLLDPSDVTAQWREGKSIVGRTQYSFITGPAVIPGYFSVDVNNVVLILNGREKAKIFYATQWLLYAQNLVQIQKLQHLAVVLLGNEHCDNEWINPFLKRNGGFVELLFIIYDSPWINDVDVFQWPLGVATYRNFPVVEASWSMLHDERPYLCNFLGTIYENSSRQALMNILKKDGNDKLCWVSAREHWQPQETNESLKNYQDALLQSDLTLCPVGVNTECYRIYEACSYGSIPVVEDVMTAGNCGNTSVHHGAPLQLLKSMGAPFIFIKNWKELPAVLEKEKTIILQEKIERRKMLLQWYQHFKTELKMKFTNILESSFLMNNKS

Target ORF information:

RefSeq Version	XM_005268563.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ribitol xylosyltransferase 1 (RXYLT1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005268563.3

ORF Insert Sequence:

ATGGCTGAGG AGACCTGCTT GTATCTCTGG GAGCATATTT TTGAAGGCTT ACTTGATCCC 
AGCGATGTGA CTGCTCAATG GAGAGAAGGA AAGTCAATCG TAGGAAGAAC ACAGTACAGC 
TTCATCACTG GTCCAGCTGT AATACCAGGG TACTTCTCCG TTGATGTGAA TAATGTGGTA 
CTCATTTTAA ATGGAAGAGA AAAAGCAAAG ATCTTTTATG CCACCCAGTG GTTACTTTAT 
GCACAAAATT TAGTGCAAAT TCAAAAACTC CAGCATCTTG CTGTTGTTTT GCTCGGAAAT 
GAACATTGTG ATAATGAGTG GATAAACCCA TTCCTCAAAA GAAATGGAGG CTTCGTGGAG 
CTGCTTTTCA TAATATATGA CAGCCCCTGG ATTAATGACG TGGATGTTTT TCAGTGGCCT 
TTAGGAGTAG CAACATACAG GAATTTTCCT GTGGTGGAGG CAAGTTGGTC AATGCTGCAT 
GATGAGAGGC CATATTTATG TAATTTCTTA GGAACGATTT ATGAAAATTC ATCCAGACAG 
GCACTAATGA ACATTTTGAA AAAAGATGGG AACGATAAGC TTTGTTGGGT TTCAGCAAGA 
GAACACTGGC AGCCTCAGGA AACAAATGAA AGTCTTAAGA ATTACCAAGA TGCCTTGCTT 
CAGAGTGATC TCACATTGTG CCCGGTCGGA GTAAACACAG AATGCTATCG AATCTATGAG 
GCTTGCTCCT ATGGCTCCAT TCCTGTGGTG GAAGACGTGA TGACAGCTGG CAACTGTGGG 
AATACATCTG TGCACCACGG TGCTCCTCTG CAGTTACTCA AGTCCATGGG TGCTCCCTTT 
ATCTTTATCA AGAACTGGAA GGAACTCCCT GCTGTTTTAG AAAAAGAGAA AACTATAATT 
TTACAAGAAA AAATTGAAAG AAGAAAAATG TTACTTCAGT GGTATCAGCA CTTCAAGACA 
GAGCTTAAAA TGAAATTTAC TAATATTTTA GAAAGCTCAT TTTTAATGAA TAATAAAAGT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RXYLT1 ( XM_005268562.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005268619.1 Homo sapiens ribitol xylosyltransferase 1 (RXYLT1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu46251
Clone ID Related Accession (Same CDS sequence)	XM_005268563.3 , XM_005268562.3
Accession Version	XM_005268562.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1023bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ribitol-5-phosphate xylosyltransferase 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000012.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005268562.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGAGG AGACCTGCTT GTATCTCTGG GAGCATATTT TTGAAGGCTT ACTTGATCCC 
AGCGATGTGA CTGCTCAATG GAGAGAAGGA AAGTCAATCG TAGGAAGAAC ACAGTACAGC 
TTCATCACTG GTCCAGCTGT AATACCAGGG TACTTCTCCG TTGATGTGAA TAATGTGGTA 
CTCATTTTAA ATGGAAGAGA AAAAGCAAAG ATCTTTTATG CCACCCAGTG GTTACTTTAT 
GCACAAAATT TAGTGCAAAT TCAAAAACTC CAGCATCTTG CTGTTGTTTT GCTCGGAAAT 
GAACATTGTG ATAATGAGTG GATAAACCCA TTCCTCAAAA GAAATGGAGG CTTCGTGGAG 
CTGCTTTTCA TAATATATGA CAGCCCCTGG ATTAATGACG TGGATGTTTT TCAGTGGCCT 
TTAGGAGTAG CAACATACAG GAATTTTCCT GTGGTGGAGG CAAGTTGGTC AATGCTGCAT 
GATGAGAGGC CATATTTATG TAATTTCTTA GGAACGATTT ATGAAAATTC ATCCAGACAG 
GCACTAATGA ACATTTTGAA AAAAGATGGG AACGATAAGC TTTGTTGGGT TTCAGCAAGA 
GAACACTGGC AGCCTCAGGA AACAAATGAA AGTCTTAAGA ATTACCAAGA TGCCTTGCTT 
CAGAGTGATC TCACATTGTG CCCGGTCGGA GTAAACACAG AATGCTATCG AATCTATGAG 
GCTTGCTCCT ATGGCTCCAT TCCTGTGGTG GAAGACGTGA TGACAGCTGG CAACTGTGGG 
AATACATCTG TGCACCACGG TGCTCCTCTG CAGTTACTCA AGTCCATGGG TGCTCCCTTT 
ATCTTTATCA AGAACTGGAA GGAACTCCCT GCTGTTTTAG AAAAAGAGAA AACTATAATT 
TTACAAGAAA AAATTGAAAG AAGAAAAATG TTACTTCAGT GGTATCAGCA CTTCAAGACA 
GAGCTTAAAA TGAAATTTAC TAATATTTTA GAAAGCTCAT TTTTAATGAA TAATAAAAGT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005268619.1
CDS	578..1600
Translation	MAEETCLYLWEHIFEGLLDPSDVTAQWREGKSIVGRTQYSFITGPAVIPGYFSVDVNNVVLILNGREKAKIFYATQWLLYAQNLVQIQKLQHLAVVLLGNEHCDNEWINPFLKRNGGFVELLFIIYDSPWINDVDVFQWPLGVATYRNFPVVEASWSMLHDERPYLCNFLGTIYENSSRQALMNILKKDGNDKLCWVSAREHWQPQETNESLKNYQDALLQSDLTLCPVGVNTECYRIYEACSYGSIPVVEDVMTAGNCGNTSVHHGAPLQLLKSMGAPFIFIKNWKELPAVLEKEKTIILQEKIERRKMLLQWYQHFKTELKMKFTNILESSFLMNNKS

Target ORF information:

RefSeq Version	XM_005268562.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ribitol xylosyltransferase 1 (RXYLT1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005268562.3

ORF Insert Sequence:

ATGGCTGAGG AGACCTGCTT GTATCTCTGG GAGCATATTT TTGAAGGCTT ACTTGATCCC 
AGCGATGTGA CTGCTCAATG GAGAGAAGGA AAGTCAATCG TAGGAAGAAC ACAGTACAGC 
TTCATCACTG GTCCAGCTGT AATACCAGGG TACTTCTCCG TTGATGTGAA TAATGTGGTA 
CTCATTTTAA ATGGAAGAGA AAAAGCAAAG ATCTTTTATG CCACCCAGTG GTTACTTTAT 
GCACAAAATT TAGTGCAAAT TCAAAAACTC CAGCATCTTG CTGTTGTTTT GCTCGGAAAT 
GAACATTGTG ATAATGAGTG GATAAACCCA TTCCTCAAAA GAAATGGAGG CTTCGTGGAG 
CTGCTTTTCA TAATATATGA CAGCCCCTGG ATTAATGACG TGGATGTTTT TCAGTGGCCT 
TTAGGAGTAG CAACATACAG GAATTTTCCT GTGGTGGAGG CAAGTTGGTC AATGCTGCAT 
GATGAGAGGC CATATTTATG TAATTTCTTA GGAACGATTT ATGAAAATTC ATCCAGACAG 
GCACTAATGA ACATTTTGAA AAAAGATGGG AACGATAAGC TTTGTTGGGT TTCAGCAAGA 
GAACACTGGC AGCCTCAGGA AACAAATGAA AGTCTTAAGA ATTACCAAGA TGCCTTGCTT 
CAGAGTGATC TCACATTGTG CCCGGTCGGA GTAAACACAG AATGCTATCG AATCTATGAG 
GCTTGCTCCT ATGGCTCCAT TCCTGTGGTG GAAGACGTGA TGACAGCTGG CAACTGTGGG 
AATACATCTG TGCACCACGG TGCTCCTCTG CAGTTACTCA AGTCCATGGG TGCTCCCTTT 
ATCTTTATCA AGAACTGGAA GGAACTCCCT GCTGTTTTAG AAAAAGAGAA AACTATAATT 
TTACAAGAAA AAATTGAAAG AAGAAAAATG TTACTTCAGT GGTATCAGCA CTTCAAGACA 
GAGCTTAAAA TGAAATTTAC TAATATTTTA GAAAGCTCAT TTTTAATGAA TAATAAAAGT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RXYLT1 ( NM_014254.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055069.1 Homo sapiens ribitol xylosyltransferase 1 (RXYLT1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21422
Clone ID Related Accession (Same CDS sequence)	NM_014254.3 , NM_014254.2
Accession Version	NM_014254.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1332bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	ribitol-5-phosphate xylosyltransferase 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC002596.2, AK289382.1, AI458269.1 and AC084357.23. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_014254.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK289382.1, DRR138512.443541.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000261234.11/ ENSP00000261234.6 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##

ATGCGGCTGA CGCGGAAGCG GCTCTGCTCG TTTCTTATCG CCCTGTACTG CCTATTCTCC 
CTCTACGCTG CCTACCACGT CTTCTTCGGG CGCCGCCGCC AGGCGCCGGC CGGGTCCCCG 
CGGGGCCTCA GGAAGGGGGC GGCCCCCGCG CGGGAGAGAC GCGGCCGAGA ACAGTCCACT 
TTGGAAAGTG AAGAATGGAA TCCTTGGGAA GGAGATGAAA AAAATGAGCA ACAACACAGA 
TTTAAAACTA GCCTTCAAAT ATTAGATAAA TCCACGAAAG GAAAAACAGA TCTCAGTGTA 
CAAATCTGGG GCAAAGCTGC CATTGGCTTG TATCTCTGGG AGCATATTTT TGAAGGCTTA 
CTTGATCCCA GCGATGTGAC TGCTCAATGG AGAGAAGGAA AGTCAATCGT AGGAAGAACA 
CAGTACAGCT TCATCACTGG TCCAGCTGTA ATACCAGGGT ACTTCTCCGT TGATGTGAAT 
AATGTGGTAC TCATTTTAAA TGGAAGAGAA AAAGCAAAGA TCTTTTATGC CACCCAGTGG 
TTACTTTATG CACAAAATTT AGTGCAAATT CAAAAACTCC AGCATCTTGC TGTTGTTTTG 
CTCGGAAATG AACATTGTGA TAATGAGTGG ATAAACCCAT TCCTCAAAAG AAATGGAGGC 
TTCGTGGAGC TGCTTTTCAT AATATATGAC AGCCCCTGGA TTAATGACGT GGATGTTTTT 
CAGTGGCCTT TAGGAGTAGC AACATACAGG AATTTTCCTG TGGTGGAGGC AAGTTGGTCA 
ATGCTGCATG ATGAGAGGCC ATATTTATGT AATTTCTTAG GAACGATTTA TGAAAATTCA 
TCCAGACAGG CACTAATGAA CATTTTGAAA AAAGATGGGA ACGATAAGCT TTGTTGGGTT 
TCAGCAAGAG AACACTGGCA GCCTCAGGAA ACAAATGAAA GTCTTAAGAA TTACCAAGAT 
GCCTTGCTTC AGAGTGATCT CACATTGTGC CCGGTCGGAG TAAACACAGA ATGCTATCGA 
ATCTATGAGG CTTGCTCCTA TGGCTCCATT CCTGTGGTGG AAGACGTGAT GACAGCTGGC 
AACTGTGGGA ATACATCTGT GCACCACGGT GCTCCTCTGC AGTTACTCAA GTCCATGGGT 
GCTCCCTTTA TCTTTATCAA GAACTGGAAG GAACTCCCTG CTGTTTTAGA AAAAGAGAAA 
ACTATAATTT TACAAGAAAA AATTGAAAGA AGAAAAATGT TACTTCAGTG GTATCAGCAC 
TTCAAGACAG AGCTTAAAAT GAAATTTACT AATATTTTAG AAAGCTCATT TTTAATGAAT 
AATAAAAGTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055069.1
CDS	53..1384
Translation	MRLTRKRLCSFLIALYCLFSLYAAYHVFFGRRRQAPAGSPRGLRKGAAPARERRGREQSTLESEEWNPWEGDEKNEQQHRFKTSLQILDKSTKGKTDLSVQIWGKAAIGLYLWEHIFEGLLDPSDVTAQWREGKSIVGRTQYSFITGPAVIPGYFSVDVNNVVLILNGREKAKIFYATQWLLYAQNLVQIQKLQHLAVVLLGNEHCDNEWINPFLKRNGGFVELLFIIYDSPWINDVDVFQWPLGVATYRNFPVVEASWSMLHDERPYLCNFLGTIYENSSRQALMNILKKDGNDKLCWVSAREHWQPQETNESLKNYQDALLQSDLTLCPVGVNTECYRIYEACSYGSIPVVEDVMTAGNCGNTSVHHGAPLQLLKSMGAPFIFIKNWKELPAVLEKEKTIILQEKIERRKMLLQWYQHFKTELKMKFTNILESSFLMNNKS

Target ORF information:

RefSeq Version	NM_014254.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ribitol xylosyltransferase 1 (RXYLT1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014254.3

ORF Insert Sequence:

ATGCGGCTGA CGCGGAAGCG GCTCTGCTCG TTTCTTATCG CCCTGTACTG CCTATTCTCC 
CTCTACGCTG CCTACCACGT CTTCTTCGGG CGCCGCCGCC AGGCGCCGGC CGGGTCCCCG 
CGGGGCCTCA GGAAGGGGGC GGCCCCCGCG CGGGAGAGAC GCGGCCGAGA ACAGTCCACT 
TTGGAAAGTG AAGAATGGAA TCCTTGGGAA GGAGATGAAA AAAATGAGCA ACAACACAGA 
TTTAAAACTA GCCTTCAAAT ATTAGATAAA TCCACGAAAG GAAAAACAGA TCTCAGTGTA 
CAAATCTGGG GCAAAGCTGC CATTGGCTTG TATCTCTGGG AGCATATTTT TGAAGGCTTA 
CTTGATCCCA GCGATGTGAC TGCTCAATGG AGAGAAGGAA AGTCAATCGT AGGAAGAACA 
CAGTACAGCT TCATCACTGG TCCAGCTGTA ATACCAGGGT ACTTCTCCGT TGATGTGAAT 
AATGTGGTAC TCATTTTAAA TGGAAGAGAA AAAGCAAAGA TCTTTTATGC CACCCAGTGG 
TTACTTTATG CACAAAATTT AGTGCAAATT CAAAAACTCC AGCATCTTGC TGTTGTTTTG 
CTCGGAAATG AACATTGTGA TAATGAGTGG ATAAACCCAT TCCTCAAAAG AAATGGAGGC 
TTCGTGGAGC TGCTTTTCAT AATATATGAC AGCCCCTGGA TTAATGACGT GGATGTTTTT 
CAGTGGCCTT TAGGAGTAGC AACATACAGG AATTTTCCTG TGGTGGAGGC AAGTTGGTCA 
ATGCTGCATG ATGAGAGGCC ATATTTATGT AATTTCTTAG GAACGATTTA TGAAAATTCA 
TCCAGACAGG CACTAATGAA CATTTTGAAA AAAGATGGGA ACGATAAGCT TTGTTGGGTT 
TCAGCAAGAG AACACTGGCA GCCTCAGGAA ACAAATGAAA GTCTTAAGAA TTACCAAGAT 
GCCTTGCTTC AGAGTGATCT CACATTGTGC CCGGTCGGAG TAAACACAGA ATGCTATCGA 
ATCTATGAGG CTTGCTCCTA TGGCTCCATT CCTGTGGTGG AAGACGTGAT GACAGCTGGC 
AACTGTGGGA ATACATCTGT GCACCACGGT GCTCCTCTGC AGTTACTCAA GTCCATGGGT 
GCTCCCTTTA TCTTTATCAA GAACTGGAAG GAACTCCCTG CTGTTTTAGA AAAAGAGAAA 
ACTATAATTT TACAAGAAAA AATTGAAAGA AGAAAAATGT TACTTCAGTG GTATCAGCAC 
TTCAAGACAG AGCTTAAAAT GAAATTTACT AATATTTTAG AAAGCTCATT TTTAATGAAT 
AATAAAAGTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RXYLT1 ( NM_014254.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_055069.1 Homo sapiens ribitol xylosyltransferase 1 (RXYLT1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21422
Clone ID Related Accession (Same CDS sequence)	NM_014254.3 , NM_014254.2
Accession Version	NM_014254.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1332bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	ribitol-5-phosphate xylosyltransferase 1 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC084357.23, BC002596.2, AK289382.1 and AI458269.1. This sequence is a reference standard in the RefSeqGene project. On May 18, 2013 this sequence version replaced NM_014254.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.140545.1, SRR1660803.57274.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGCGGCTGA CGCGGAAGCG GCTCTGCTCG TTTCTTATCG CCCTGTACTG CCTATTCTCC 
CTCTACGCTG CCTACCACGT CTTCTTCGGG CGCCGCCGCC AGGCGCCGGC CGGGTCCCCG 
CGGGGCCTCA GGAAGGGGGC GGCCCCCGCG CGGGAGAGAC GCGGCCGAGA ACAGTCCACT 
TTGGAAAGTG AAGAATGGAA TCCTTGGGAA GGAGATGAAA AAAATGAGCA ACAACACAGA 
TTTAAAACTA GCCTTCAAAT ATTAGATAAA TCCACGAAAG GAAAAACAGA TCTCAGTGTA 
CAAATCTGGG GCAAAGCTGC CATTGGCTTG TATCTCTGGG AGCATATTTT TGAAGGCTTA 
CTTGATCCCA GCGATGTGAC TGCTCAATGG AGAGAAGGAA AGTCAATCGT AGGAAGAACA 
CAGTACAGCT TCATCACTGG TCCAGCTGTA ATACCAGGGT ACTTCTCCGT TGATGTGAAT 
AATGTGGTAC TCATTTTAAA TGGAAGAGAA AAAGCAAAGA TCTTTTATGC CACCCAGTGG 
TTACTTTATG CACAAAATTT AGTGCAAATT CAAAAACTCC AGCATCTTGC TGTTGTTTTG 
CTCGGAAATG AACATTGTGA TAATGAGTGG ATAAACCCAT TCCTCAAAAG AAATGGAGGC 
TTCGTGGAGC TGCTTTTCAT AATATATGAC AGCCCCTGGA TTAATGACGT GGATGTTTTT 
CAGTGGCCTT TAGGAGTAGC AACATACAGG AATTTTCCTG TGGTGGAGGC AAGTTGGTCA 
ATGCTGCATG ATGAGAGGCC ATATTTATGT AATTTCTTAG GAACGATTTA TGAAAATTCA 
TCCAGACAGG CACTAATGAA CATTTTGAAA AAAGATGGGA ACGATAAGCT TTGTTGGGTT 
TCAGCAAGAG AACACTGGCA GCCTCAGGAA ACAAATGAAA GTCTTAAGAA TTACCAAGAT 
GCCTTGCTTC AGAGTGATCT CACATTGTGC CCGGTCGGAG TAAACACAGA ATGCTATCGA 
ATCTATGAGG CTTGCTCCTA TGGCTCCATT CCTGTGGTGG AAGACGTGAT GACAGCTGGC 
AACTGTGGGA ATACATCTGT GCACCACGGT GCTCCTCTGC AGTTACTCAA GTCCATGGGT 
GCTCCCTTTA TCTTTATCAA GAACTGGAAG GAACTCCCTG CTGTTTTAGA AAAAGAGAAA 
ACTATAATTT TACAAGAAAA AATTGAAAGA AGAAAAATGT TACTTCAGTG GTATCAGCAC 
TTCAAGACAG AGCTTAAAAT GAAATTTACT AATATTTTAG AAAGCTCATT TTTAATGAAT 
AATAAAAGTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055069.1
CDS	159..1490
Translation	MRLTRKRLCSFLIALYCLFSLYAAYHVFFGRRRQAPAGSPRGLRKGAAPARERRGREQSTLESEEWNPWEGDEKNEQQHRFKTSLQILDKSTKGKTDLSVQIWGKAAIGLYLWEHIFEGLLDPSDVTAQWREGKSIVGRTQYSFITGPAVIPGYFSVDVNNVVLILNGREKAKIFYATQWLLYAQNLVQIQKLQHLAVVLLGNEHCDNEWINPFLKRNGGFVELLFIIYDSPWINDVDVFQWPLGVATYRNFPVVEASWSMLHDERPYLCNFLGTIYENSSRQALMNILKKDGNDKLCWVSAREHWQPQETNESLKNYQDALLQSDLTLCPVGVNTECYRIYEACSYGSIPVVEDVMTAGNCGNTSVHHGAPLQLLKSMGAPFIFIKNWKELPAVLEKEKTIILQEKIERRKMLLQWYQHFKTELKMKFTNILESSFLMNNKS

Target ORF information:

RefSeq Version	NM_014254.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ribitol xylosyltransferase 1 (RXYLT1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014254.2

ORF Insert Sequence:

ATGCGGCTGA CGCGGAAGCG GCTCTGCTCG TTTCTTATCG CCCTGTACTG CCTATTCTCC 
CTCTACGCTG CCTACCACGT CTTCTTCGGG CGCCGCCGCC AGGCGCCGGC CGGGTCCCCG 
CGGGGCCTCA GGAAGGGGGC GGCCCCCGCG CGGGAGAGAC GCGGCCGAGA ACAGTCCACT 
TTGGAAAGTG AAGAATGGAA TCCTTGGGAA GGAGATGAAA AAAATGAGCA ACAACACAGA 
TTTAAAACTA GCCTTCAAAT ATTAGATAAA TCCACGAAAG GAAAAACAGA TCTCAGTGTA 
CAAATCTGGG GCAAAGCTGC CATTGGCTTG TATCTCTGGG AGCATATTTT TGAAGGCTTA 
CTTGATCCCA GCGATGTGAC TGCTCAATGG AGAGAAGGAA AGTCAATCGT AGGAAGAACA 
CAGTACAGCT TCATCACTGG TCCAGCTGTA ATACCAGGGT ACTTCTCCGT TGATGTGAAT 
AATGTGGTAC TCATTTTAAA TGGAAGAGAA AAAGCAAAGA TCTTTTATGC CACCCAGTGG 
TTACTTTATG CACAAAATTT AGTGCAAATT CAAAAACTCC AGCATCTTGC TGTTGTTTTG 
CTCGGAAATG AACATTGTGA TAATGAGTGG ATAAACCCAT TCCTCAAAAG AAATGGAGGC 
TTCGTGGAGC TGCTTTTCAT AATATATGAC AGCCCCTGGA TTAATGACGT GGATGTTTTT 
CAGTGGCCTT TAGGAGTAGC AACATACAGG AATTTTCCTG TGGTGGAGGC AAGTTGGTCA 
ATGCTGCATG ATGAGAGGCC ATATTTATGT AATTTCTTAG GAACGATTTA TGAAAATTCA 
TCCAGACAGG CACTAATGAA CATTTTGAAA AAAGATGGGA ACGATAAGCT TTGTTGGGTT 
TCAGCAAGAG AACACTGGCA GCCTCAGGAA ACAAATGAAA GTCTTAAGAA TTACCAAGAT 
GCCTTGCTTC AGAGTGATCT CACATTGTGC CCGGTCGGAG TAAACACAGA ATGCTATCGA 
ATCTATGAGG CTTGCTCCTA TGGCTCCATT CCTGTGGTGG AAGACGTGAT GACAGCTGGC 
AACTGTGGGA ATACATCTGT GCACCACGGT GCTCCTCTGC AGTTACTCAA GTCCATGGGT 
GCTCCCTTTA TCTTTATCAA GAACTGGAAG GAACTCCCTG CTGTTTTAGA AAAAGAGAAA 
ACTATAATTT TACAAGAAAA AATTGAAAGA AGAAAAATGT TACTTCAGTG GTATCAGCAC 
TTCAAGACAG AGCTTAAAAT GAAATTTACT AATATTTTAG AAAGCTCATT TTTAATGAAT 
AATAAAAGTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

The Muscular Dystrophy Gene TMEM5 Encodes a Ribitol ?1,4-Xylosyltransferase Required for the Functional Glycosylation of Dystroglycan.
The Journal of biological chemistry291(47)24618-24627(2016 Nov)
Manya H,Yamaguchi Y,Kanagawa M,Kobayashi K,Tajiri M,Akasaka-Manya K,Kawakami H,Mizuno M,Wada Y,Toda T,Endo T

The functional O-mannose glycan on ?-dystroglycan contains a phospho-ribitol primed for matriglycan addition.
eLife5(2016 04)
Praissman JL,Willer T,Sheikh MO,Toi A,Chitayat D,Lin YY,Lee H,Stalnaker SH,Wang S,Prabhakar PK,Nelson SF,Stemple DL,Moore SA,Moremen KW,Campbell KP,Wells L

The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated ?-dystroglycan functional glycosylation.
eLife3(2014 Oct)
Willer T,Inamori K,Venzke D,Harvey C,Morgensen G,Hara Y,Beltr?n Valero de Bernab? D,Yu L,Wright KM,Campbell KP

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RXYLT1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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FAX

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