DEFB131B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	DEFB131B
Entrez Gene ID	100129216
Full Name	defensin beta 131B
General protein information	Preferred Names defensin beta 131B Names beta-defensin 131B defensin, beta 131
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q13.4

mRNA and Protein(s)

mRNA	Protein	Name
NM_001242853.1	NP_001229782.1	beta-defensin 131B precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	LOC100129216	NP_001229782.1
Pan troglodytes (chimpanzee)	DEFB131	NP_001123251.1
Homo sapiens (human)	DEFB131	NP_001035538.2
	DEFB131	XP_001085667.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression of Beta-Defensin 131 Promotes an Innate Immune Response in Human Prostate Epithelial Cells.
Kim JH, Kim KH, Kim HJ, Lee J, Myung SC
PloS one10(12)e0144776(2015)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following DEFB131B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DEFB131B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu28961	NM_001242853.1 Latest version!	Homo sapiens defensin beta 131B (DEFB131B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DEFB131B ( NM_001242853.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001229782.1 Homo sapiens defensin beta 131B (DEFB131B), mRNA.

Price & Availability↑

CloneID	OHu28961
Clone ID Related Accession (Same CDS sequence)	NM_001242853.1
Accession Version	NM_001242853.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 213bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-29
Organism	Homo sapiens(human)
Product	beta-defensin 131B precursor
Comment	Comment: INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from AP002495.3. On or before Jul 1, 2011 this sequence version replaced XM_001723168.1, XM_001724868.1, XM_001723261.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make a sequence comparable to human DEFB131 NM_001040448.2. The genomic coordinates used for the transcript record were based on alignments. CCDS Note: This CCDS representation lacks full-length human transcript support. Its exon combination is therefore inferred, but it is supported by paralogous transcripts. ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000530210.1/ ENSP00000485141.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGAGGGTCT TGTTTTTTGT CTTTGGAGTC CTTTCCTTGA TGTCCACAGT TCCTCCAACC 
AGAAGCTTCA CTTCTAATGA TGAATGTCCT TCAGAATATT ATCATTGCAG ACTGAAGTGC 
AATGCTGATG AACATGCAAT TAGATACTGT GCTGACTTCA GCATCTGCTG CAAACTGAAG 
ATCATTCAAA TTGATGGACA AAAGAAGTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001229782.1
CDS	1..213
Translation	MRVLFFVFGVLSLMSTVPPTRSFTSNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLKIIQIDGQKKW

Target ORF information:

RefSeq Version	NM_001242853.1
Organism	Homo sapiens(human)
Definition	Homo sapiens defensin beta 131B (DEFB131B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001242853.1

ORF Insert Sequence:

ATGAGGGTCT TGTTTTTTGT CTTTGGAGTC CTTTCCTTGA TGTCCACAGT TCCTCCAACC 
AGAAGCTTCA CTTCTAATGA TGAATGTCCT TCAGAATATT ATCATTGCAG ACTGAAGTGC 
AATGCTGATG AACATGCAAT TAGATACTGT GCTGACTTCA GCATCTGCTG CAAACTGAAG 
ATCATTCAAA TTGATGGACA AAAGAAGTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression of Beta-Defensin 131 Promotes an Innate Immune Response in Human Prostate Epithelial Cells.
PloS one10(12)e0144776(2015)
Kim JH,Kim KH,Kim HJ,Lee J,Myung SC