HMGCS2 cDNA ORF clone, Heterocephalus glaber(Naked mole-rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	HMGCS2
Entrez Gene ID	101712063
Full Name	3-hydroxy-3-methylglutaryl-CoA synthase 2
Gene Type	protein-coding
Organism	Heterocephalus glaber(Naked mole-rat)

mRNA and Protein(s)

mRNA	Protein	Name
XM_004853851.3	XP_004853908.1	hydroxymethylglutaryl-CoA synthase, mitochondrial
XM_004853851.2	XP_004853908.1	hydroxymethylglutaryl-CoA synthase, mitochondrial

Pathways from BioSystems
Gene Ontology

The following HMGCS2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HMGCS2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHe47528	XM_004853851.3 Latest version!	Heterocephalus glaber 3-hydroxy-3-methylglutaryl-CoA synthase 2 (Hmgcs2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$342.30 $489.00
View Old Accession Versions >>
OHe47528	XM_004853851.2	Heterocephalus glaber 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) (Hmgcs2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$342.30 $489.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HMGCS2 ( XM_004853851.3 ) cDNA ORF clone, Heterocephalus glaber(Naked mole-rat) -> XP_004853908.1 Heterocephalus glaber 3-hydroxy-3-methylglutaryl-CoA synthase 2 (Hmgcs2), mRNA.

Price & Availability↑

CloneID	OHe47528
Clone ID Related Accession (Same CDS sequence)	XM_004853851.3 , XM_004853851.2
Accession Version	XM_004853851.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1527bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-05-22
Organism	Heterocephalus glaber(naked mole-rat)
Product	hydroxymethylglutaryl-CoA synthase, mitochondrial
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_004624772.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 23, 2017 this sequence version replaced XM_004853851.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Heterocephalus glaber Annotation Release 102 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGCGGC TACTGACTCC GGTGCGGCAG GTCCTGCAAG TGAAGAGGGT GATTCGGGAA 
GCTTCCCTCA CACCTGTGCG CCTGCTCCCA GCAGCCCACC AAAGGTTATT TACAATCTCT 
GCTGCCCCCC TGGCCAAAAC AGATACGTGG CCAAAAGATG TGGGCATCCT TGACCTGGAG 
GTCTACTTCC CAGCCCAATA CGTGGACCAA ACTGACCTGG AGAAGTACAA CAAGGTGGAA 
GCAGGGAAGT ATACAGTGGG CTTGGGTCAG ACCCAAATGG GCTTCTGCTC CGTCCAGGAG 
GACATCAACT CCCTGTGCCT GACGGTAGTG CAACGGCTGA TGGAGCGCAC AAAGCTCCCA 
TGGGATTCCG TGGGCCGACT GGAAGTCGGC ACTGAGACCA TCATCGACAA GTCTAAGGCT 
GTCAAAACGG TGCTCATGGA ACTGTTCCAG GAGTCAGGCA ACACTGACAT TGAGGGCATA 
GATACCACCA ATGCGTGCTA TGGTGGCACT GCTTCCCTCT TCAATGCTGC CAACTGGATG 
GAGTCCAGCT ACTGGGATGG TCGCTACGCG CTGGTGGTCT GTGGAGACAT TGCAGTGTAC 
CCCAATGGTA ATGCGCGCCC CACGGGTGGC GCTGGAGCTG TGGCCATGCT GATTGGGCCT 
AACGCCCCTC TAGCCCTGGA GCAAGGACTT AGAGGAACCC ACATGGAGAA TGCCTATGAC 
TTCTACAAAC CAAATTTGGC CTCAGAGTAC CCGTTGGTGG ATGGCAAGCT CTCCATCCAG 
TGTTACTTCC GGGCCTTGGA CAGATGCTAC ACATCATACC GCCGAAAAAT CCAGAATCAG 
TGGAAGCAAG ATGGCATCGA CCGACCTTTC ACCCTTGACG ATATACAGTA TATGATCTTT 
CACACACCCT TTTGCAAGAT GGTCCAGAAA TCTCTGGCTC GCCTGATGTT CAGTGATTTC 
CTGTCATCCA GCAGTGCCAC ACAGAACACC TCATATAAGG GACTGGAGGC CTTCAGGAAC 
CTAAAGCTGG AAGAAACATA CACCAACAAG GATGTGGATA AAGCCCTTCT GAAAGCCTCC 
CTGGACATAT TCAACAAGAA GACCAAGGCC TCCCTCTACC TCTCCACACA CAACGGGAAC 
ATGTACACCT CATCCCTGTA TGGCTGTCTG GCCTCGCTTC TGGCACATCA CTCTGCTCAA 
GAATTGGCTG GCTCCAGGAT CGGTGCCTTC TCCTATGGCT CTGGCTTAGC AGCAAGTTTG 
TTCTCATTTC GAGTGTCCCA GGATGCTTCT CCTGGCTCCC CATTGGAGAA GCTGGTGTCT 
AGTGTATCAG ACCTGCCAAA ACGTCTGGCC TCCCGGAAGC GTATGTCTCC TGAAGAATTC 
ACAGAAGTAA TGAACCAAAG AGAGCAATTC TACCACAAGG TGAATTTCTC ACCACCCGGT 
GACACAAATA ACCTTTTCCC GGGTACTTGG TACCTCGAGC GAGTGGACGA GATGCATCGC 
CGGAAGTATG CCCGGCATCC CATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_004853908.1
CDS	101..1627
Translation	MQRLLTPVRQVLQVKRVIREASLTPVRLLPAAHQRLFTISAAPLAKTDTWPKDVGILDLEVYFPAQYVDQTDLEKYNKVEAGKYTVGLGQTQMGFCSVQEDINSLCLTVVQRLMERTKLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQESGNTDIEGIDTTNACYGGTASLFNAANWMESSYWDGRYALVVCGDIAVYPNGNARPTGGAGAVAMLIGPNAPLALEQGLRGTHMENAYDFYKPNLASEYPLVDGKLSIQCYFRALDRCYTSYRRKIQNQWKQDGIDRPFTLDDIQYMIFHTPFCKMVQKSLARLMFSDFLSSSSATQNTSYKGLEAFRNLKLEETYTNKDVDKALLKASLDIFNKKTKASLYLSTHNGNMYTSSLYGCLASLLAHHSAQELAGSRIGAFSYGSGLAASLFSFRVSQDASPGSPLEKLVSSVSDLPKRLASRKRMSPEEFTEVMNQREQFYHKVNFSPPGDTNNLFPGTWYLERVDEMHRRKYARHPI

Target ORF information:

RefSeq Version	XM_004853851.3
Organism	Heterocephalus glaber(naked mole-rat)
Definition	Heterocephalus glaber 3-hydroxy-3-methylglutaryl-CoA synthase 2 (Hmgcs2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_004853851.3

ORF Insert Sequence:

ATGCAGCGGC TACTGACTCC GGTGCGGCAG GTCCTGCAAG TGAAGAGGGT GATTCGGGAA 
GCTTCCCTCA CACCTGTGCG CCTGCTCCCA GCAGCCCACC AAAGGTTATT TACAATCTCT 
GCTGCCCCCC TGGCCAAAAC AGATACGTGG CCAAAAGATG TGGGCATCCT TGACCTGGAG 
GTCTACTTCC CAGCCCAATA CGTGGACCAA ACTGACCTGG AGAAGTACAA CAAGGTGGAA 
GCAGGGAAGT ATACAGTGGG CTTGGGTCAG ACCCAAATGG GCTTCTGCTC CGTCCAGGAG 
GACATCAACT CCCTGTGCCT GACGGTAGTG CAACGGCTGA TGGAGCGCAC AAAGCTCCCA 
TGGGATTCCG TGGGCCGACT GGAAGTCGGC ACTGAGACCA TCATCGACAA GTCTAAGGCT 
GTCAAAACGG TGCTCATGGA ACTGTTCCAG GAGTCAGGCA ACACTGACAT TGAGGGCATA 
GATACCACCA ATGCGTGCTA TGGTGGCACT GCTTCCCTCT TCAATGCTGC CAACTGGATG 
GAGTCCAGCT ACTGGGATGG TCGCTACGCG CTGGTGGTCT GTGGAGACAT TGCAGTGTAC 
CCCAATGGTA ATGCGCGCCC CACGGGTGGC GCTGGAGCTG TGGCCATGCT GATTGGGCCT 
AACGCCCCTC TAGCCCTGGA GCAAGGACTT AGAGGAACCC ACATGGAGAA TGCCTATGAC 
TTCTACAAAC CAAATTTGGC CTCAGAGTAC CCGTTGGTGG ATGGCAAGCT CTCCATCCAG 
TGTTACTTCC GGGCCTTGGA CAGATGCTAC ACATCATACC GCCGAAAAAT CCAGAATCAG 
TGGAAGCAAG ATGGCATCGA CCGACCTTTC ACCCTTGACG ATATACAGTA TATGATCTTT 
CACACACCCT TTTGCAAGAT GGTCCAGAAA TCTCTGGCTC GCCTGATGTT CAGTGATTTC 
CTGTCATCCA GCAGTGCCAC ACAGAACACC TCATATAAGG GACTGGAGGC CTTCAGGAAC 
CTAAAGCTGG AAGAAACATA CACCAACAAG GATGTGGATA AAGCCCTTCT GAAAGCCTCC 
CTGGACATAT TCAACAAGAA GACCAAGGCC TCCCTCTACC TCTCCACACA CAACGGGAAC 
ATGTACACCT CATCCCTGTA TGGCTGTCTG GCCTCGCTTC TGGCACATCA CTCTGCTCAA 
GAATTGGCTG GCTCCAGGAT CGGTGCCTTC TCCTATGGCT CTGGCTTAGC AGCAAGTTTG 
TTCTCATTTC GAGTGTCCCA GGATGCTTCT CCTGGCTCCC CATTGGAGAA GCTGGTGTCT 
AGTGTATCAG ACCTGCCAAA ACGTCTGGCC TCCCGGAAGC GTATGTCTCC TGAAGAATTC 
ACAGAAGTAA TGAACCAAAG AGAGCAATTC TACCACAAGG TGAATTTCTC ACCACCCGGT 
GACACAAATA ACCTTTTCCC GGGTACTTGG TACCTCGAGC GAGTGGACGA GATGCATCGC 
CGGAAGTATG CCCGGCATCC CATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HMGCS2 ( XM_004853851.2 ) cDNA ORF clone, Heterocephalus glaber(Naked mole-rat) -> XP_004853908.1 Heterocephalus glaber 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) (Hmgcs2), mRNA.

Price & Availability↑

CloneID	OHe47528
Clone ID Related Accession (Same CDS sequence)	XM_004853851.3 , XM_004853851.2
Accession Version	XM_004853851.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1527bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-07-01
Organism	Heterocephalus glaber(Naked mole-rat)
Product	hydroxymethylglutaryl-CoA synthase, mitochondrial
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_004624772.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 2, 2015 this sequence version replaced XM_004853851.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Heterocephalus glaber Annotation Release 101 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.3 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGCGGC TACTGACTCC GGTGCGGCAG GTCCTGCAAG TGAAGAGGGT GATTCGGGAA 
GCTTCCCTCA CACCTGTGCG CCTGCTCCCA GCAGCCCACC AAAGGTTATT TACAATCTCT 
GCTGCCCCCC TGGCCAAAAC AGATACGTGG CCAAAAGATG TGGGCATCCT TGACCTGGAG 
GTCTACTTCC CAGCCCAATA CGTGGACCAA ACTGACCTGG AGAAGTACAA CAAGGTGGAA 
GCAGGGAAGT ATACAGTGGG CTTGGGTCAG ACCCAAATGG GCTTCTGCTC CGTCCAGGAG 
GACATCAACT CCCTGTGCCT GACGGTAGTG CAACGGCTGA TGGAGCGCAC AAAGCTCCCA 
TGGGATTCCG TGGGCCGACT GGAAGTCGGC ACTGAGACCA TCATCGACAA GTCTAAGGCT 
GTCAAAACGG TGCTCATGGA ACTGTTCCAG GAGTCAGGCA ACACTGACAT TGAGGGCATA 
GATACCACCA ATGCGTGCTA TGGTGGCACT GCTTCCCTCT TCAATGCTGC CAACTGGATG 
GAGTCCAGCT ACTGGGATGG TCGCTACGCG CTGGTGGTCT GTGGAGACAT TGCAGTGTAC 
CCCAATGGTA ATGCGCGCCC CACGGGTGGC GCTGGAGCTG TGGCCATGCT GATTGGGCCT 
AACGCCCCTC TAGCCCTGGA GCAAGGACTT AGAGGAACCC ACATGGAGAA TGCCTATGAC 
TTCTACAAAC CAAATTTGGC CTCAGAGTAC CCGTTGGTGG ATGGCAAGCT CTCCATCCAG 
TGTTACTTCC GGGCCTTGGA CAGATGCTAC ACATCATACC GCCGAAAAAT CCAGAATCAG 
TGGAAGCAAG ATGGCATCGA CCGACCTTTC ACCCTTGACG ATATACAGTA TATGATCTTT 
CACACACCCT TTTGCAAGAT GGTCCAGAAA TCTCTGGCTC GCCTGATGTT CAGTGATTTC 
CTGTCATCCA GCAGTGCCAC ACAGAACACC TCATATAAGG GACTGGAGGC CTTCAGGAAC 
CTAAAGCTGG AAGAAACATA CACCAACAAG GATGTGGATA AAGCCCTTCT GAAAGCCTCC 
CTGGACATAT TCAACAAGAA GACCAAGGCC TCCCTCTACC TCTCCACACA CAACGGGAAC 
ATGTACACCT CATCCCTGTA TGGCTGTCTG GCCTCGCTTC TGGCACATCA CTCTGCTCAA 
GAATTGGCTG GCTCCAGGAT CGGTGCCTTC TCCTATGGCT CTGGCTTAGC AGCAAGTTTG 
TTCTCATTTC GAGTGTCCCA GGATGCTTCT CCTGGCTCCC CATTGGAGAA GCTGGTGTCT 
AGTGTATCAG ACCTGCCAAA ACGTCTGGCC TCCCGGAAGC GTATGTCTCC TGAAGAATTC 
ACAGAAGTAA TGAACCAAAG AGAGCAATTC TACCACAAGG TGAATTTCTC ACCACCCGGT 
GACACAAATA ACCTTTTCCC GGGTACTTGG TACCTCGAGC GAGTGGACGA GATGCATCGC 
CGGAAGTATG CCCGGCATCC CATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_004853908.1
CDS	91..1617
Translation	MQRLLTPVRQVLQVKRVIREASLTPVRLLPAAHQRLFTISAAPLAKTDTWPKDVGILDLEVYFPAQYVDQTDLEKYNKVEAGKYTVGLGQTQMGFCSVQEDINSLCLTVVQRLMERTKLPWDSVGRLEVGTETIIDKSKAVKTVLMELFQESGNTDIEGIDTTNACYGGTASLFNAANWMESSYWDGRYALVVCGDIAVYPNGNARPTGGAGAVAMLIGPNAPLALEQGLRGTHMENAYDFYKPNLASEYPLVDGKLSIQCYFRALDRCYTSYRRKIQNQWKQDGIDRPFTLDDIQYMIFHTPFCKMVQKSLARLMFSDFLSSSSATQNTSYKGLEAFRNLKLEETYTNKDVDKALLKASLDIFNKKTKASLYLSTHNGNMYTSSLYGCLASLLAHHSAQELAGSRIGAFSYGSGLAASLFSFRVSQDASPGSPLEKLVSSVSDLPKRLASRKRMSPEEFTEVMNQREQFYHKVNFSPPGDTNNLFPGTWYLERVDEMHRRKYARHPI

Target ORF information:

RefSeq Version	XM_004853851.2
Organism	Heterocephalus glaber(Naked mole-rat)
Definition	Heterocephalus glaber 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) (Hmgcs2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_004853851.2

ORF Insert Sequence:

ATGCAGCGGC TACTGACTCC GGTGCGGCAG GTCCTGCAAG TGAAGAGGGT GATTCGGGAA 
GCTTCCCTCA CACCTGTGCG CCTGCTCCCA GCAGCCCACC AAAGGTTATT TACAATCTCT 
GCTGCCCCCC TGGCCAAAAC AGATACGTGG CCAAAAGATG TGGGCATCCT TGACCTGGAG 
GTCTACTTCC CAGCCCAATA CGTGGACCAA ACTGACCTGG AGAAGTACAA CAAGGTGGAA 
GCAGGGAAGT ATACAGTGGG CTTGGGTCAG ACCCAAATGG GCTTCTGCTC CGTCCAGGAG 
GACATCAACT CCCTGTGCCT GACGGTAGTG CAACGGCTGA TGGAGCGCAC AAAGCTCCCA 
TGGGATTCCG TGGGCCGACT GGAAGTCGGC ACTGAGACCA TCATCGACAA GTCTAAGGCT 
GTCAAAACGG TGCTCATGGA ACTGTTCCAG GAGTCAGGCA ACACTGACAT TGAGGGCATA 
GATACCACCA ATGCGTGCTA TGGTGGCACT GCTTCCCTCT TCAATGCTGC CAACTGGATG 
GAGTCCAGCT ACTGGGATGG TCGCTACGCG CTGGTGGTCT GTGGAGACAT TGCAGTGTAC 
CCCAATGGTA ATGCGCGCCC CACGGGTGGC GCTGGAGCTG TGGCCATGCT GATTGGGCCT 
AACGCCCCTC TAGCCCTGGA GCAAGGACTT AGAGGAACCC ACATGGAGAA TGCCTATGAC 
TTCTACAAAC CAAATTTGGC CTCAGAGTAC CCGTTGGTGG ATGGCAAGCT CTCCATCCAG 
TGTTACTTCC GGGCCTTGGA CAGATGCTAC ACATCATACC GCCGAAAAAT CCAGAATCAG 
TGGAAGCAAG ATGGCATCGA CCGACCTTTC ACCCTTGACG ATATACAGTA TATGATCTTT 
CACACACCCT TTTGCAAGAT GGTCCAGAAA TCTCTGGCTC GCCTGATGTT CAGTGATTTC 
CTGTCATCCA GCAGTGCCAC ACAGAACACC TCATATAAGG GACTGGAGGC CTTCAGGAAC 
CTAAAGCTGG AAGAAACATA CACCAACAAG GATGTGGATA AAGCCCTTCT GAAAGCCTCC 
CTGGACATAT TCAACAAGAA GACCAAGGCC TCCCTCTACC TCTCCACACA CAACGGGAAC 
ATGTACACCT CATCCCTGTA TGGCTGTCTG GCCTCGCTTC TGGCACATCA CTCTGCTCAA 
GAATTGGCTG GCTCCAGGAT CGGTGCCTTC TCCTATGGCT CTGGCTTAGC AGCAAGTTTG 
TTCTCATTTC GAGTGTCCCA GGATGCTTCT CCTGGCTCCC CATTGGAGAA GCTGGTGTCT 
AGTGTATCAG ACCTGCCAAA ACGTCTGGCC TCCCGGAAGC GTATGTCTCC TGAAGAATTC 
ACAGAAGTAA TGAACCAAAG AGAGCAATTC TACCACAAGG TGAATTTCTC ACCACCCGGT 
GACACAAATA ACCTTTTCCC GGGTACTTGG TACCTCGAGC GAGTGGACGA GATGCATCGC 
CGGAAGTATG CCCGGCATCC CATCTAA