IL8L2 cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	IL8L2
Entrez Gene ID	396495
Full Name	interleukin 8-like 2
Synonyms	CXCL8,CXCLi2,EMF-1,IL8
General protein information	Preferred Names interleukin 8-like 2 Names interleukin-8 9E3 C-X-C motif chemokine 8 CEF-4 CEF-4/9E3 cytokine IL-8 RSV-induced protein chemokine (C-X-C motif) ligand 8 embryo fibroblast protein 1 putatitve interleukin-8 transformation-induced protein
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_205498.1	NP_990829.1	interleukin-8 precursor

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	IL8L1	NP_990349.1
Xenopus tropicalis (tropical clawed frog)	LOC100498234	XP_002942576.1
Gallus gallus (chicken)	IL8L2	NP_990829.1

Gene Ontology
Bibliography

Related articles in PubMed

Lower interleukin-8 levels in airway aspirates from breastfed infants with acute bronchiolitis.
Dixon DL, Griggs KM, Forsyth KD, Bersten AD
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology21(4 Pt 2)e691-6(2010 Jun)

Expression profiles of genes in Toll-like receptor-mediated signaling of broilers infected with Clostridium perfringens.
Lu Y, Sarson AJ, Gong J, Zhou H, Zhu W, Kang Z, Yu H, Sharif S, Han Y
Clinical and vaccine immunology : CVI16(11)1639-47(2009 Nov)

Structural and functional homology among chicken, duck, goose, turkey and pigeon interleukin-8 proteins.
Wu YF, Shien JH, Yin HH, Chiow SH, Lee LH
Veterinary immunology and immunopathology125(3-4)205-15(2008 Oct)

Re-evaluation of chicken CXCR1 determines the true gene structure: CXCLi1 (K60) and CXCLi2 (CAF/interleukin-8) are ligands for this receptor.
Poh TY, Pease J, Young JR, Bumstead N, Kaiser P
The Journal of biological chemistry283(24)16408-15(2008 Jun)

Development and adaptations of innate immunity in the gastrointestinal tract of the newly hatched chick.
Bar-Shira E, Friedman A
Developmental and comparative immunology30(10)930-41(2006)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Lower levels in airway aspirates from breastfed infants with acute bronchiolitis
Title: Lower interleukin-8 levels in airway aspirates from breastfed infants with acute bronchiolitis.

CXCLi1 (K60) and CXCLi2 (CAF/interleukin-8) look equally like orthologues of human CXCL8 and are ligands for chicken CXCR1
Title: Re-evaluation of chicken CXCR1 determines the true gene structure: CXCLi1 (K60) and CXCLi2 (CAF/interleukin-8) are ligands for this receptor.

Authors use expression of pro-inflammatory cytokines IL1b, IL8 and CCL4/K203 to demonstrate development of innate immunity in hatchling's gut
Title: Development and adaptations of innate immunity in the gastrointestinal tract of the newly hatched chick.

The following IL8L2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL8L2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa00729	NM_205498.1 Latest version!	Gallus gallus interleukin 8-like 2 (IL8L2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$104.30 $149.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IL8L2 ( NM_205498.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_990829.1 Gallus gallus interleukin 8-like 2 (IL8L2), mRNA.

Price & Availability↑

CloneID	OGa00729
Clone ID Related Accession (Same CDS sequence)	NM_205498.1
Accession Version	NM_205498.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 312bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Gallus gallus(chicken)
Product	interleukin-8 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M16199.1. On Aug 30, 2004 this sequence version replaced XM_444659.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M16199.1, J02975.1 [ECO:0000332] ##Evidence-Data-END##

ATGAACGGCA AGCTTGGAGC TGTCCTGGCC CTCCTCCTGG TTTCAGCTGC TCTGTCGCAA 
GGTAGGACGC TGGTAAAGAT GGGGAATGAG CTGCGGTGCC AGTGCATTAG CACTCATTCT 
AAGTTCATCC ACCCTAAATC CATTCAAGAT GTGAAGCTGA CGCCAAGCGG CCCCCACTGC 
AAGAATGTTG AAATCATAGC TACTCTAAAG GATGGAAGAG AGGTGTGCTT GGACCCCACT 
GCTCCCTGGG TACAGCTGAT CGTAAAGGCA CTTATGGCCA AGGCTCAGCT CAATTCTGAT 
GCACCACTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_990829.1
CDS	78..389
Translation	MNGKLGAVLALLLVSAALSQGRTLVKMGNELRCQCISTHSKFIHPKSIQDVKLTPSGPHCKNVEIIATLKDGREVCLDPTAPWVQLIVKALMAKAQLNSDAPL

Target ORF information:

RefSeq Version	NM_205498.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus interleukin 8-like 2 (IL8L2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_205498.1

ORF Insert Sequence:

ATGAACGGCA AGCTTGGAGC TGTCCTGGCC CTCCTCCTGG TTTCAGCTGC TCTGTCGCAA 
GGTAGGACGC TGGTAAAGAT GGGGAATGAG CTGCGGTGCC AGTGCATTAG CACTCATTCT 
AAGTTCATCC ACCCTAAATC CATTCAAGAT GTGAAGCTGA CGCCAAGCGG CCCCCACTGC 
AAGAATGTTG AAATCATAGC TACTCTAAAG GATGGAAGAG AGGTGTGCTT GGACCCCACT 
GCTCCCTGGG TACAGCTGAT CGTAAAGGCA CTTATGGCCA AGGCTCAGCT CAATTCTGAT 
GCACCACTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Lower interleukin-8 levels in airway aspirates from breastfed infants with acute bronchiolitis.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology21(4 Pt 2)e691-6(2010 Jun)
Dixon DL,Griggs KM,Forsyth KD,Bersten AD

Expression profiles of genes in Toll-like receptor-mediated signaling of broilers infected with Clostridium perfringens.
Clinical and vaccine immunology : CVI16(11)1639-47(2009 Nov)
Lu Y,Sarson AJ,Gong J,Zhou H,Zhu W,Kang Z,Yu H,Sharif S,Han Y

Structural and functional homology among chicken, duck, goose, turkey and pigeon interleukin-8 proteins.
Veterinary immunology and immunopathology125(3-4)205-15(2008 Oct)
Wu YF,Shien JH,Yin HH,Chiow SH,Lee LH

Re-evaluation of chicken CXCR1 determines the true gene structure: CXCLi1 (K60) and CXCLi2 (CAF/interleukin-8) are ligands for this receptor.
The Journal of biological chemistry283(24)16408-15(2008 Jun)
Poh TY,Pease J,Young JR,Bumstead N,Kaiser P

Development and adaptations of innate immunity in the gastrointestinal tract of the newly hatched chick.
Developmental and comparative immunology30(10)930-41(2006)
Bar-Shira E,Friedman A