SST cDNA ORF clone, Gallus gallus(chicken)

Gene
Clones
gRNAs

Summary

Gene Symbol	SST
Entrez Gene ID	396279
Full Name	somatostatin
Synonyms	SRIF,SS,SS1
General protein information	Preferred Names somatostatin Names somatostatin somatostatin-14 somatostatin-28
Gene Type	protein-coding
Organism	Gallus gallus(chicken)

mRNA and Protein(s)

mRNA	Protein	Name
NM_205336.1	NP_990667.1	somatostatin precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SST	NP_001003307.1
Mus musculus (house mouse)	Sst	NP_033241.1
Danio rerio (zebrafish)	sst1.1	NP_898893.1
	SST	XP_001103516.1
Gallus gallus (chicken)	SST	NP_990667.1
Bos taurus (cattle)	SST	NP_776385.1
Xenopus tropicalis (tropical clawed frog)	LOC100486511	XP_002944417.2
Xenopus tropicalis (tropical clawed frog)	sst	NP_001090807.1
Homo sapiens (human)	SST	NP_001039.1
Pan troglodytes (chimpanzee)	SST	XP_003310215.1
Rattus norvegicus (Norway rat)	Sst	NP_036791.1

Gene Ontology
Bibliography

Related articles in PubMed

Neuropeptides: developmental signals in placode progenitor formation.
Lleras-Forero L, Tambalo M, Christophorou N, Chambers D, Houart C, Streit A
Developmental cell26(2)195-203(2013 Jul)

The cortistatin gene PSS2 rather than the somatostatin gene PSS1 is strongly expressed in developing avian autonomic neurons.
Nishi R, Stubbusch J, Hulce JJ, Hruska M, Pappas A, Bravo MC, Huber LP, Bakondi B, Soltys J, Rohrer H
The Journal of comparative neurology518(6)839-50(2010 Mar)

Somatostatin peptides produce multiple effects on gating properties of native cone photoreceptor cGMP-gated channels that depend on circadian phase and previous illumination.
Chen SK, Ko GY, Dryer SE
The Journal of neuroscience : the official journal of the Society for Neuroscience27(45)12168-75(2007 Nov)

Characterization of the cDNA encoding a somatostatin variant in the chicken brain: comparison of the distribution of the two somatostatin precursor mRNAs.
Trabucchi M, Tostivint H, Lihrmann I, Bl?hser S, Vallarino M, Vaudry H
The Journal of comparative neurology461(4)441-51(2003 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Mesendoderm-derived somatostatin promotes aPP identity in the overlying ectoderm by regulating Eya2 and nociceptin. Nociceptin controls its own expression and, together with somatostatin, the onset of Pax6, a key regulator of eye and olfactory fates.
Title: Neuropeptides: developmental signals in placode progenitor formation.

We conclude that much of the somatostatin-like immunoreactivity in the developing avian peripheral nervous system is actually cortistatin, the PSS2 product, as opposed to true somatostatin, which is the PSS1 product.
Title: The cortistatin gene PSS2 rather than the somatostatin gene PSS1 is strongly expressed in developing avian autonomic neurons.

SS14 and SS28 modulate cone photoreceptor cyclic GMP-gated channels through multiple mechanisms
Title: Somatostatin peptides produce multiple effects on gating properties of native cone photoreceptor cGMP-gated channels that depend on circadian phase and previous illumination.

The following SST gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SST cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OGa27814	NM_205336.1 Latest version!	Gallus gallus somatostatin (SST), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SST ( NM_205336.1 ) cDNA ORF clone, Gallus gallus(chicken) -> NP_990667.1 Gallus gallus somatostatin (SST), mRNA.

Price & Availability↑

CloneID	OGa27814
Clone ID Related Accession (Same CDS sequence)	NM_205336.1
Accession Version	NM_205336.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 351bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Gallus gallus(chicken)
Product	somatostatin precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X60191.1. Sequence Note: This sequence has been modified as follows: removed 17 bp suspected to be vector contamination from the 5' end. ##Evidence-Data-START## Transcript exon combination :: X60191.1, CN210817.1 [ECO:0000332] ##Evidence-Data-END##

ATGCTGTCGT GCCGCCTGCA GTGCGCCCTG GCCCTGCTCT CCATCGCCTT GGCCGTCGGC 
ACCGTCTCGG CCGCCCCCTC GGACCCCCGG CTCCGGCAGT TCCTGCAGAA GTCCCTGGCT 
GCCGCCGCCG GGAAGCAGGA ACTGGCCAAG TACTTTTTGG CAGAACTGCT CTCAGAGCCA 
AGCCAGACAG AAAATGAAGC TCTGGAGTCG GAGGACTTGT CCCGAGGGGC CGAGCAGGAT 
GAAGTGAGAC TGGAGCTGGA GCGCTCGGCC AACTCAAACC CCGCGCTGGC TCCCCGGGAA 
CGCAAAGCGG GCTGCAAGAA CTTCTTCTGG AAAACTTTCA CATCCTGTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_990667.1
CDS	23..373
Translation	MLSCRLQCALALLSIALAVGTVSAAPSDPRLRQFLQKSLAAAAGKQELAKYFLAELLSEPSQTENEALESEDLSRGAEQDEVRLELERSANSNPALAPRERKAGCKNFFWKTFTSC

Target ORF information:

RefSeq Version	NM_205336.1
Organism	Gallus gallus(chicken)
Definition	Gallus gallus somatostatin (SST), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_205336.1

ORF Insert Sequence:

ATGCTGTCGT GCCGCCTGCA GTGCGCCCTG GCCCTGCTCT CCATCGCCTT GGCCGTCGGC 
ACCGTCTCGG CCGCCCCCTC GGACCCCCGG CTCCGGCAGT TCCTGCAGAA GTCCCTGGCT 
GCCGCCGCCG GGAAGCAGGA ACTGGCCAAG TACTTTTTGG CAGAACTGCT CTCAGAGCCA 
AGCCAGACAG AAAATGAAGC TCTGGAGTCG GAGGACTTGT CCCGAGGGGC CGAGCAGGAT 
GAAGTGAGAC TGGAGCTGGA GCGCTCGGCC AACTCAAACC CCGCGCTGGC TCCCCGGGAA 
CGCAAAGCGG GCTGCAAGAA CTTCTTCTGG AAAACTTTCA CATCCTGTTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Neuropeptides: developmental signals in placode progenitor formation.
Developmental cell26(2)195-203(2013 Jul)
Lleras-Forero L,Tambalo M,Christophorou N,Chambers D,Houart C,Streit A

The cortistatin gene PSS2 rather than the somatostatin gene PSS1 is strongly expressed in developing avian autonomic neurons.
The Journal of comparative neurology518(6)839-50(2010 Mar)
Nishi R,Stubbusch J,Hulce JJ,Hruska M,Pappas A,Bravo MC,Huber LP,Bakondi B,Soltys J,Rohrer H

Somatostatin peptides produce multiple effects on gating properties of native cone photoreceptor cGMP-gated channels that depend on circadian phase and previous illumination.
The Journal of neuroscience : the official journal of the Society for Neuroscience27(45)12168-75(2007 Nov)
Chen SK,Ko GY,Dryer SE

Characterization of the cDNA encoding a somatostatin variant in the chicken brain: comparison of the distribution of the two somatostatin precursor mRNAs.
The Journal of comparative neurology461(4)441-51(2003 Jul)
Trabucchi M,Tostivint H,Lihrmann I,Bl?hser S,Vallarino M,Vaudry H