IL5 cDNA ORF clone, Equus caballus(horse)

Gene
Clones
gRNAs

Summary

Gene Symbol	IL5
Entrez Gene ID	100034199
Full Name	interleukin 5
Synonyms	IL-5
Gene Type	protein-coding
Organism	Equus caballus(horse)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001082499.1	NP_001075968.1	interleukin-5 precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Annotation of the Protein Coding Regions of the Equine Genome.
Hestand MS, Kalbfleisch TS, Coleman SJ, Zeng Z, Liu J, Orlando L, MacLeod JN
PloS one10(6)e0124375(2015)

Clinical alterations and mRNA levels of IL-4 and IL-5 in bronchoalveolar cells of horses with transient pulmonary eosinophilia.
Riihim?ki M, Lillieh??k I, Raine A, Berg M, Pringle J
Research in veterinary science85(1)52-5(2008 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study showed that pronounced lung eosinophilia in horses can be transient, abate without specific treatment, and in this instance, lack correlation to upregulation of expression of either IL-4 or IL-5.
Title: Clinical alterations and mRNA levels of IL-4 and IL-5 in bronchoalveolar cells of horses with transient pulmonary eosinophilia.

The following IL5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IL5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHb00314	NM_001082499.1 Latest version!	Equus caballus interleukin 5 (IL5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IL5 ( NM_001082499.1 ) cDNA ORF clone, Equus caballus(horse) -> NP_001075968.1 Equus caballus interleukin 5 (IL5), mRNA.

Price & Availability↑

CloneID	OHb00314
Clone ID Related Accession (Same CDS sequence)	NM_001082499.1
Accession Version	NM_001082499.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 405bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Equus caballus(horse)
Product	interleukin-5 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U91947.1. ##Evidence-Data-START## Transcript exon combination :: U91947.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2743238, SAMN04870173 [ECO:0000348] ##Evidence-Data-END##

ATGAGGATGC TTCTGCATTT GAGTGTGCTA GCTCTTGGAG CTGCCTACGT CTGTGCCCTT 
GCTGTAGAAA GTCCCATGAA CAGACTAGTG GCAGAGACCT TGACACTGCT CTCCACTCAT 
CGAACTCTGC TGATAGGCGA TGGGAACCTG ATGATTCCTA CTCCTGAACA TAAAAATCAC 
CAACTCTGCA TTGAAGAAGT CTTTCAGGGA ATAGACACAT TGAAGAATCA AACTGTCCAA 
GGGGATGCTG TGGCCAAACT ATTCCAAAAC TTGTCTTTAA TAAAAGGATA CATAGACCTC 
CAAAAAAAAA AGTGTGGAGG AGAAAGATGG AGAGTGAAAC AATTCCTAGA CTACCTGCAG 
GAGTTTCTTG GTGTAATAAA CACTGAGTGG ACAATAGAAG GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001075968.1
CDS	1..405
Translation	MRMLLHLSVLALGAAYVCALAVESPMNRLVAETLTLLSTHRTLLIGDGNLMIPTPEHKNHQLCIEEVFQGIDTLKNQTVQGDAVAKLFQNLSLIKGYIDLQKKKCGGERWRVKQFLDYLQEFLGVINTEWTIEG

Target ORF information:

RefSeq Version	NM_001082499.1
Organism	Equus caballus(horse)
Definition	Equus caballus interleukin 5 (IL5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001082499.1

ORF Insert Sequence:

ATGAGGATGC TTCTGCATTT GAGTGTGCTA GCTCTTGGAG CTGCCTACGT CTGTGCCCTT 
GCTGTAGAAA GTCCCATGAA CAGACTAGTG GCAGAGACCT TGACACTGCT CTCCACTCAT 
CGAACTCTGC TGATAGGCGA TGGGAACCTG ATGATTCCTA CTCCTGAACA TAAAAATCAC 
CAACTCTGCA TTGAAGAAGT CTTTCAGGGA ATAGACACAT TGAAGAATCA AACTGTCCAA 
GGGGATGCTG TGGCCAAACT ATTCCAAAAC TTGTCTTTAA TAAAAGGATA CATAGACCTC 
CAAAAAAAAA AGTGTGGAGG AGAAAGATGG AGAGTGAAAC AATTCCTAGA CTACCTGCAG 
GAGTTTCTTG GTGTAATAAA CACTGAGTGG ACAATAGAAG GCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Annotation of the Protein Coding Regions of the Equine Genome.
PloS one10(6)e0124375(2015)
Hestand MS,Kalbfleisch TS,Coleman SJ,Zeng Z,Liu J,Orlando L,MacLeod JN

Clinical alterations and mRNA levels of IL-4 and IL-5 in bronchoalveolar cells of horses with transient pulmonary eosinophilia.
Research in veterinary science85(1)52-5(2008 Aug)
Riihim?ki M,Lillieh??k I,Raine A,Berg M,Pringle J