hrh2a cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	hrh2a
Entrez Gene ID	735303
Full Name	histamine receptor H2a
Synonyms	hrh2
General protein information	Preferred Names histamine receptor H2a Names histamine H2 receptor histamine receptor H2
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001045338.2	NP_001038803.2	histamine H2 receptor

Pathways from BioSystems

Homologies

Homo sapiens (human)	HRH2	NP_071640.1
	HRH2	XP_001082927.1
Mus musculus (house mouse)	Hrh2	NP_001010973.1
Gallus gallus (chicken)	HRH2	XP_004944962.1
Anopheles gambiae (African malaria mosquito)	GPRNNA3	XP_003436281.1
Rattus norvegicus (Norway rat)	Hrh2	NP_037097.3
Xenopus tropicalis (tropical clawed frog)	hrh2	XP_002938111.1
Pan troglodytes (chimpanzee)	HRH2	NP_001009124.1
Drosophila melanogaster (fruit fly)	Octbeta3R	NP_001034043.2
Canis lupus familiaris (dog)	HRH2	NP_001182773.1
Bos taurus (cattle)	LOC521257	XP_005211286.1
Danio rerio (zebrafish)	hrh2	NP_001038803.1

Gene Ontology
Bibliography

Related articles in PubMed

Genetic Analysis of Histamine Signaling in Larval Zebrafish Sleep.
Chen A, Singh C, Oikonomou G, Prober DA
eNeuro4(1)(2017 Jan-Feb)

Modulation of Fgfr1a signaling in zebrafish reveals a genetic basis for the aggression-boldness syndrome.
Norton WH, Stumpenhorst K, Faus-Kessler T, Folchert A, Rohner N, Harris MP, Callebert J, Bally-Cuif L
The Journal of neuroscience : the official journal of the Society for Neuroscience31(39)13796-807(2011 Sep)

Unravelling the neurophysiological basis of aggression in a fish model.
Filby AL, Paull GC, Hickmore TF, Tyler CR
BMC genomics11498(2010 Sep)

Identification of zebrafish histamine H1, H2 and H3 receptors and effects of histaminergic ligands on behavior.
Peitsaro N, Sundvik M, Anichtchik OV, Kaslin J, Panula P
Biochemical pharmacology73(8)1205-14(2007 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following hrh2a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the hrh2a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa46465	NM_001045338.2 Latest version!	Danio rerio histamine receptor H2a (hrh2a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

hrh2a ( NM_001045338.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001038803.2 Danio rerio histamine receptor H2a (hrh2a), mRNA.

Price & Availability↑

CloneID	ODa46465
Clone ID Related Accession (Same CDS sequence)	NM_001045338.2
Accession Version	NM_001045338.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1110bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-06
Organism	Danio rerio(zebrafish)
Product	histamine H2 receptor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CABZ01064228.1. On Jun 17, 2015 this sequence version replaced NM_001045338.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript is intronless :: BC162730.1 [ECO:0000345] ##Evidence-Data-END##

ATGACATCCC AGATAGCTTT AGCTGTGACG CTCTCCGTCC TCATCCTGCT CACTGTAAGT 
GGGAATATTC TGGTCTGTCT GGCTGTGTAT GCTACGAGAC GCTTGCGTAA CGTCACCAAC 
TGCTTCATCG TTTCGCTAGC GGTAACAGAT TTCCTACTGG GCGCACTCGT GCTGCCATTT 
TCAACTCTTT ACCAGGTTAC GGGAGACTGG CCACTAGGGG CGCACTTCTG CAACATCTAC 
ATCTCACTGG ACGTCATGCT ATGCACCGCC TCCATACTCA ACCTCTTCGC CATTAGCTTG 
GATCGCTACT TTGCGGTCAC TGCTCCGCTA CGATACCCAA TGCTAGTGCT TCCATGGCGA 
GTCGGAGCGA TTCTAGCGAC AATATGGTTG GTTTCGGTGG GCGTTTCATT CGTGCCTATT 
CACCTAGGAT GGAATACGCG CGATTTAAGC GTGCAAAATA TTCGCGAGGG CGACCATGCT 
AGAGACTGTA GATTCGAGCT GAATCCGACG TACGCCATCG TGGATGCTTT CTCAACGTTT 
TATCTCCCCC TGCTGGCCAT GTGTTGGAGC TACCACCGAG TGTTTCGCAT CGCAAGGATG 
CGAGCGAAAC GGATTATTTC TACGCGCCGC GGTTCGACGT CTTCGCAGGG CGTGACGATT 
CTAACATTGC GCGAACATAA AGCAACGGTG ACTCTCGCGG TTGTCCTTGG TGCGTTTGTA 
GTGTGCTGGT TTCCATATTT CACGTTTTTT ACGATAATGG GAATACGTAA CGAAGAAAAC 
CCTCCACAGA CTGCGCAGTC TGTCGTGCTT TGGCTGGGAT ACGCCAACTC TGCGCTAAAC 
CCTGTACTTT ACGCTACGCT AAACAGAGAC TTCAGATCTG CCTACGCAAA GCTGCTGTGT 
GGAGGGAGAC GGTGTAAAAC AGAGACAACA ATACCGATAG CTGCAACGGC GGCGGGGACA 
ATGACTGGAC ACGCCCATTC TTCAAAAGGG GCGGGGTTTC TGCCTAGAAC TTGTGTATTG 
CTGAAAGACT CTGAAAACAG GATGCTGGAC GATAACAGCG CTACAAATGG TGCTACGGTT 
ACTGTTGTAG CTAATGGGAG TAAAAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001038803.2
CDS	195..1304
Translation	MTSQIALAVTLSVLILLTVSGNILVCLAVYATRRLRNVTNCFIVSLAVTDFLLGALVLPFSTLYQVTGDWPLGAHFCNIYISLDVMLCTASILNLFAISLDRYFAVTAPLRYPMLVLPWRVGAILATIWLVSVGVSFVPIHLGWNTRDLSVQNIREGDHARDCRFELNPTYAIVDAFSTFYLPLLAMCWSYHRVFRIARMRAKRIISTRRGSTSSQGVTILTLREHKATVTLAVVLGAFVVCWFPYFTFFTIMGIRNEENPPQTAQSVVLWLGYANSALNPVLYATLNRDFRSAYAKLLCGGRRCKTETTIPIAATAAGTMTGHAHSSKGAGFLPRTCVLLKDSENRMLDDNSATNGATVTVVANGSKR

Target ORF information:

RefSeq Version	NM_001045338.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio histamine receptor H2a (hrh2a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001045338.2

ORF Insert Sequence:

ATGACATCCC AGATAGCTTT AGCTGTGACG CTCTCCGTCC TCATCCTGCT CACTGTAAGT 
GGGAATATTC TGGTCTGTCT GGCTGTGTAT GCTACGAGAC GCTTGCGTAA CGTCACCAAC 
TGCTTCATCG TTTCGCTAGC GGTAACAGAT TTCCTACTGG GCGCACTCGT GCTGCCATTT 
TCAACTCTTT ACCAGGTTAC GGGAGACTGG CCACTAGGGG CGCACTTCTG CAACATCTAC 
ATCTCACTGG ACGTCATGCT ATGCACCGCC TCCATACTCA ACCTCTTCGC CATTAGCTTG 
GATCGCTACT TTGCGGTCAC TGCTCCGCTA CGATACCCAA TGCTAGTGCT TCCATGGCGA 
GTCGGAGCGA TTCTAGCGAC AATATGGTTG GTTTCGGTGG GCGTTTCATT CGTGCCTATT 
CACCTAGGAT GGAATACGCG CGATTTAAGC GTGCAAAATA TTCGCGAGGG CGACCATGCT 
AGAGACTGTA GATTCGAGCT GAATCCGACG TACGCCATCG TGGATGCTTT CTCAACGTTT 
TATCTCCCCC TGCTGGCCAT GTGTTGGAGC TACCACCGAG TGTTTCGCAT CGCAAGGATG 
CGAGCGAAAC GGATTATTTC TACGCGCCGC GGTTCGACGT CTTCGCAGGG CGTGACGATT 
CTAACATTGC GCGAACATAA AGCAACGGTG ACTCTCGCGG TTGTCCTTGG TGCGTTTGTA 
GTGTGCTGGT TTCCATATTT CACGTTTTTT ACGATAATGG GAATACGTAA CGAAGAAAAC 
CCTCCACAGA CTGCGCAGTC TGTCGTGCTT TGGCTGGGAT ACGCCAACTC TGCGCTAAAC 
CCTGTACTTT ACGCTACGCT AAACAGAGAC TTCAGATCTG CCTACGCAAA GCTGCTGTGT 
GGAGGGAGAC GGTGTAAAAC AGAGACAACA ATACCGATAG CTGCAACGGC GGCGGGGACA 
ATGACTGGAC ACGCCCATTC TTCAAAAGGG GCGGGGTTTC TGCCTAGAAC TTGTGTATTG 
CTGAAAGACT CTGAAAACAG GATGCTGGAC GATAACAGCG CTACAAATGG TGCTACGGTT 
ACTGTTGTAG CTAATGGGAG TAAAAGGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genetic Analysis of Histamine Signaling in Larval Zebrafish Sleep.
eNeuro4(1)(2017 Jan-Feb)
Chen A,Singh C,Oikonomou G,Prober DA

Modulation of Fgfr1a signaling in zebrafish reveals a genetic basis for the aggression-boldness syndrome.
The Journal of neuroscience : the official journal of the Society for Neuroscience31(39)13796-807(2011 Sep)
Norton WH,Stumpenhorst K,Faus-Kessler T,Folchert A,Rohner N,Harris MP,Callebert J,Bally-Cuif L

Unravelling the neurophysiological basis of aggression in a fish model.
BMC genomics11498(2010 Sep)
Filby AL,Paull GC,Hickmore TF,Tyler CR

Identification of zebrafish histamine H1, H2 and H3 receptors and effects of histaminergic ligands on behavior.
Biochemical pharmacology73(8)1205-14(2007 Apr)
Peitsaro N,Sundvik M,Anichtchik OV,Kaslin J,Panula P