myl2b cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	myl2b
Entrez Gene ID	677750
Full Name	myosin, light chain 2b, regulatory, cardiac, slow
Synonyms	myl2,zgc:136848
General protein information	Preferred Names myosin, light chain 2b, regulatory, cardiac, slow Names myosin, light chain 2b, regulatory, cardiac, slow myosin, light polypeptide 2, regulatory, cardiac, slow myosin, light polypeptide 2b, regulatory, cardiac, slow
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001040045.1	NP_001035134.1	myosin, light chain 2b, regulatory, cardiac, slow
XM_021478314.1	XP_021333989.1	myosin, light chain 2b, regulatory, cardiac, slow isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Myl2	NP_001030329.2
Gallus gallus (chicken)	MYL2	NP_001258858.1
Canis lupus familiaris (dog)	MYL2	NP_001003069.1
Danio rerio (zebrafish)	myl2b	NP_001035134.1
Danio rerio (zebrafish)	LOC100537244	XP_003198611.2
Xenopus tropicalis (tropical clawed frog)	myl2	NP_001107717.1
Pan troglodytes (chimpanzee)	MYL2	XP_001144828.2
Mus musculus (house mouse)	Myl2	NP_034991.3
Bos taurus (cattle)	MYL2	NP_001030197.1
Homo sapiens (human)	MYL2	NP_000423.2
	MYL2	XP_001100796.1

Gene Ontology
Bibliography

Related articles in PubMed

"Young at heart": Regenerative potential linked to immature cardiac phenotypes.
Gomes RS, Skroblin P, Munster AB, Tomlins H, Langley SR, Zampetaki A, Yin X, Wardle FC, Mayr M
Journal of molecular and cellular cardiology92105-8(2016 Mar)

Evolution and Expression of Paxillin Genes in Teleost Fish.
Jacob AE, Turner CE, Amack JD
PloS one11(11)e0165266(2016)

Depletion of zebrafish essential and regulatory myosin light chains reduces cardiac function through distinct mechanisms.
Chen Z, Huang W, Dahme T, Rottbauer W, Ackerman MJ, Xu X
Cardiovascular research79(1)97-108(2008 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following myl2b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the myl2b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa03707	NM_001040045.1 Latest version!	Danio rerio myosin, light chain 2b, regulatory, cardiac, slow (myl2b), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
ODa143719	XM_021478314.1 Latest version!	Danio rerio myosin, light chain 2b, regulatory, cardiac, slow (myl2b), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$104.30 $149.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

myl2b ( NM_001040045.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001035134.1 Danio rerio myosin, light chain 2b, regulatory, cardiac, slow (myl2b), mRNA.

Price & Availability↑

CloneID	ODa03707
Clone ID Related Accession (Same CDS sequence)	NM_001040045.1
Accession Version	NM_001040045.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 507bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-25
Organism	Danio rerio(zebrafish)
Product	myosin, light chain 2b, regulatory, cardiac, slow
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC114289.1. ##Evidence-Data-START## Transcript exon combination :: BC114289.1, CF266243.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END##

ATGGCACCCA AAAAGGCAAA GAAGCGGGCC GAAGGAGCCA ACTCCAACGT CTTCTCCATG 
TTCGAACAAG CTCAGATCCA GGAGTTCAAA GAGGCTTTCA CTATCATGGA CCAGAACAGA 
GACGGCTTTA TCGACAAGAA TGACCTGCGG GACACGTTCG CAGCTTTAGG CCGGCTGAAC 
GTCAAACAGG AGGAGCTGGA TGAGATGCTG AAGGAGGCTC CGGGACCCAT CAACTTTACC 
GTCTTCCTCA CCATGTTTGG AGAGAAGCTT AAAGGTGCCG ATGCAGAGGA GACCATCCTC 
AATGCCTTTA AAGTGTTCGA CCCCGAGGGA AAGGGGACCT TGAGGAAGGA TTTTTTGTCA 
CGGATGTTGA CAACACAAGC GGACAGATTC TCTCCAGAAG AGATGGAGCA GATGTTTAGC 
GCTTTTCCTC CAGACGCTGC TGGAAATCTG GACTACAAGA ATCTGGTGTA CATCATCACT 
CACGGGGAGG AGAAAGACCA AGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001035134.1
CDS	6..512
Translation	MAPKKAKKRAEGANSNVFSMFEQAQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRLNVKQEELDEMLKEAPGPINFTVFLTMFGEKLKGADAEETILNAFKVFDPEGKGTLRKDFLSRMLTTQADRFSPEEMEQMFSAFPPDAAGNLDYKNLVYIITHGEEKDQE

Target ORF information:

RefSeq Version	NM_001040045.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio myosin, light chain 2b, regulatory, cardiac, slow (myl2b), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001040045.1

ORF Insert Sequence:

ATGGCACCCA AAAAGGCAAA GAAGCGGGCC GAAGGAGCCA ACTCCAACGT CTTCTCCATG 
TTCGAACAAG CTCAGATCCA GGAGTTCAAA GAGGCTTTCA CTATCATGGA CCAGAACAGA 
GACGGCTTTA TCGACAAGAA TGACCTGCGG GACACGTTCG CAGCTTTAGG CCGGCTGAAC 
GTCAAACAGG AGGAGCTGGA TGAGATGCTG AAGGAGGCTC CGGGACCCAT CAACTTTACC 
GTCTTCCTCA CCATGTTTGG AGAGAAGCTT AAAGGTGCCG ATGCAGAGGA GACCATCCTC 
AATGCCTTTA AAGTGTTCGA CCCCGAGGGA AAGGGGACCT TGAGGAAGGA TTTTTTGTCA 
CGGATGTTGA CAACACAAGC GGACAGATTC TCTCCAGAAG AGATGGAGCA GATGTTTAGC 
GCTTTTCCTC CAGACGCTGC TGGAAATCTG GACTACAAGA ATCTGGTGTA CATCATCACT 
CACGGGGAGG AGAAAGACCA AGAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

myl2b ( XM_021478314.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_021333989.1 Danio rerio myosin, light chain 2b, regulatory, cardiac, slow (myl2b), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa143719
Clone ID Related Accession (Same CDS sequence)	XM_021478314.1
Accession Version	XM_021478314.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 378bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-06-14
Organism	Danio rerio(zebrafish)
Product	myosin, light chain 2b, regulatory, cardiac, slow isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007119.7) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGTTGA ATATGTATAT AAAATCAGCA TTTCCACTCG CGCTCAAATC ACTTCTGCTT 
CATCTCCTGC TTTCAAGGGT TACGATTATG GCACCCAAAA AGGCAAAGAA GCGGGCCGAA 
GGAGCCAACT CCAACGTCTT CTCCATGTTC GAACAAGCTC AGATCCAGGA GTTCAAAGAG 
GCTTTCACTA TCATGGACCA GAACAGAGAC GGCTTTATCG ACAAGAATGA CCTGCGGGAC 
ACGTTCGCAG CTTTAGGCCG GCTGAACGTC AAACAGGAGG AGCTGGATGA GATGCTGAAG 
GAGGCTCCGG GACCCATCAA CTTTACCGTC TTCCTCACCA TGTTTGGAGA GAAGCTTAAA 
GTTTGTCACG GATGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_021333989.1
CDS	16..393
Translation	MGLNMYIKSAFPLALKSLLLHLLLSRVTIMAPKKAKKRAEGANSNVFSMFEQAQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRLNVKQEELDEMLKEAPGPINFTVFLTMFGEKLKVCHGC

Target ORF information:

RefSeq Version	XM_021478314.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio myosin, light chain 2b, regulatory, cardiac, slow (myl2b), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_021478314.1

ORF Insert Sequence:

ATGGGGTTGA ATATGTATAT AAAATCAGCA TTTCCACTCG CGCTCAAATC ACTTCTGCTT 
CATCTCCTGC TTTCAAGGGT TACGATTATG GCACCCAAAA AGGCAAAGAA GCGGGCCGAA 
GGAGCCAACT CCAACGTCTT CTCCATGTTC GAACAAGCTC AGATCCAGGA GTTCAAAGAG 
GCTTTCACTA TCATGGACCA GAACAGAGAC GGCTTTATCG ACAAGAATGA CCTGCGGGAC 
ACGTTCGCAG CTTTAGGCCG GCTGAACGTC AAACAGGAGG AGCTGGATGA GATGCTGAAG 
GAGGCTCCGG GACCCATCAA CTTTACCGTC TTCCTCACCA TGTTTGGAGA GAAGCTTAAA 
GTTTGTCACG GATGTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

"Young at heart": Regenerative potential linked to immature cardiac phenotypes.
Journal of molecular and cellular cardiology92105-8(2016 Mar)
Gomes RS,Skroblin P,Munster AB,Tomlins H,Langley SR,Zampetaki A,Yin X,Wardle FC,Mayr M

Evolution and Expression of Paxillin Genes in Teleost Fish.
PloS one11(11)e0165266(2016)
Jacob AE,Turner CE,Amack JD

Depletion of zebrafish essential and regulatory myosin light chains reduces cardiac function through distinct mechanisms.
Cardiovascular research79(1)97-108(2008 Jul)
Chen Z,Huang W,Dahme T,Rottbauer W,Ackerman MJ,Xu X