ints6 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	ints6
Entrez Gene ID	569456
Full Name	integrator complex subunit 6
Synonyms	ddx26a
General protein information	Preferred Names integrator complex subunit 6 Names integrator complex subunit 6 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001126428.1	NP_001119900.1	integrator complex subunit 6

Pathways from BioSystems

Homologies

Homo sapiens (human)	INTS6	NP_036273.1
Danio rerio (zebrafish)	ints6	NP_001119900.1
Gallus gallus (chicken)	INTS6	XP_417071.3
	INTS6	XP_001105975.2
Canis lupus familiaris (dog)	INTS6	XP_534109.5
Mus musculus (house mouse)	Ints6	NP_032741.2
Pan troglodytes (chimpanzee)	INTS6	XP_003314197.1
Bos taurus (cattle)	INTS6	XP_002691790.2
Rattus norvegicus (Norway rat)	Ints6	NP_001258417.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000631	XP_001230769.3

Gene Ontology
Bibliography

Related articles in PubMed

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

The integrator complex subunit 6 (Ints6) confines the dorsal organizer in vertebrate embryogenesis.
Kapp LD, Abrams EW, Marlow FL, Mullins MC
PLoS genetics9(10)e1003822(2013 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Our results are consistent with a novel role for Ints6 in restricting the vertebrate organizer to a dorsal domain in embryonic patterning.
Title: The integrator complex subunit 6 (Ints6) confines the dorsal organizer in vertebrate embryogenesis.

The following ints6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ints6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa02335	NM_001126428.1 Latest version!	Danio rerio integrator complex subunit 6 (ints6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$510.30 $729.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ints6 ( NM_001126428.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001119900.1 Danio rerio integrator complex subunit 6 (ints6), mRNA.

Price & Availability↑

CloneID	ODa02335
Clone ID Related Accession (Same CDS sequence)	NM_001126428.1
Accession Version	NM_001126428.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2565bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-23
Organism	Danio rerio(zebrafish)
Product	integrator complex subunit 6
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CR533429.7. On Jul 31, 2008 this sequence version replaced XM_692847.3. ##Evidence-Data-START## Transcript exon combination :: BC059197.1, GDQQ01009978.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGCCCGTGC TACTTTTTCT AATAGACACG TCCGCCTCCA TGAACCAGCG CTCCCATCTG 
GGCACTAGCT ATCTGGACAT AGCGAAGGGC GCAGTTGAGA CTTTCCTGAA GCTGAGAAGC 
AGAGATCCGG CCAGCAGGGG AGACAGATAC ATGTTAGTGA GTTTCGAGGA AGCGCCGGCT 
GGCATTAAGG CTGGATGGAA GGACAGTCAT GCCACTTTTA TGACTGAGCT AAGGAACCTG 
CAAGCAGTTG GACTGACATC GTTTGGCCAA GCTTTAAGGA CAGCTTTTGA TTTGCTCAAT 
CTTAATAGAT TAGTTTCAGG GATAGACAAC TATGGACAGG GTAGAAACCC TTTTTTCTTG 
GAACCTGCTA TCATTGTGGC CATAACTGAT GGCAGCAAGC TGACTGGCAG CTCTGGGGTA 
CAAGATGAGT TACATTTACC GTTAACAACA CCATTACCTG GCAGTGAACT GACCAAAGAG 
CCCTTTCGAT GGGACCAGCG ACTCTTCTCT TTAGTGCTGC GTGTTCCAGG CCATGCCTCT 
GCTGACCCTG AACCAGTGGG TGGAGTTCCA CTCGACTCCT CCCCTATTAC ACCCATGTGT 
GAGGTCACCG GAGGCCGATC ATACAGCGTG TTTTCCCAGA GAATGCTGAA CCAGTGCCTG 
GAGTCTTTGG TACAGAAGAT ACAGAGTGGT GTGGTCATCA ATTTTGAGAA GACTGGACCT 
GATCCTTCTC CTACTGAAGA TGGTCCAATA GAGGTGAAGC ATGGACCTCA AGTATGGCAC 
AGCTGTCATA AATTGATCTA TGTGAGACCC AACCCTAAAA CTGGTGTACC TGTTGGCCAT 
TGGCCTATCC CTGAATCCTT CTGGCCTGAC CAGAACTCTC CTACTTTGCC TCCACGTGCA 
GCTCACCCTC ATGTGAAGTT TTCATGTGTG GATTCGGAGC CCATGGTGGT AGATAAAGTG 
CCCTTCGACA AGTATGAGCT GGAGCCTTCC CCGCTCACCC AGTACATTCT AGAGAGGAAA 
TCACCACATA CCTGCTGGCA GGTTTTTGTG TGTAACAGTG CTAAATATGG AGAACTGGGT 
CAACCGTTTG GATATCTGAA GGCTAGCACA GCTCTCAACT GTGTCAACCT GTTTGTTATG 
CCCTATAACT ATCCTGTGGT GCTTCCATTG CTTGATGACT TAATTGTTGT GCATAAGTTC 
AAGCCTCCAG TGAAGTGGCG ACAGTCTTTT GAAAATTATC TTAAAACAAT GCCCCCCTAC 
TACATCCCAG CCCTGCGGAA AGCATTAAGA ATGATGGGGG CTCCAAACCT GTTAGCAGAC 
AACATGGAAT ATGGCCTCAG CTACAGTGTT GTGTCTTATC TTAAAAAGCT CAGTCAGCAG 
GCGAAGATCG AGGCAGACCG AGTTTGTGCT TCAGTGGGAA AAAAAGTGGC ACCAGAAGGT 
GGAATTAAAC TTCGTTGTAG GAGCTCTGCT CTATCCCTGG CAAACAGGAA GGATTTCACA 
CAGCTTCTGC AGAGCATCAT GGGAGATGGA CCAGCACTTC CAATGGAGGC AAACACCAAG 
GAGTTTGCTG GCTTTCAGCT GGCTTCCTTG AATAAAGCAT TAAAACCACA GGGCTTGCGC 
AACCCTTACG ATATCCCAAG AGCTCATCTT CTGGACCAGC TGAGCCGCAT GAGGAGGAAC 
CTTCTGCATG CCAGTATCTG TATTCTCAAA GGGCAAGATC AAGATCAGCT TCACAGTGTG 
CCTATAGCTC AGATGGGCAA CTATCAGGAC TTCTTGAAGC ATTGCCCATC ACCTCTGAGA 
GAGGCAGACC CTGATCAGCC CAAACGTCTG CACACCTTTG GTAACCCCTT TAAACTGGAC 
AAGAAGGCCA TGATGGTGGA TGAGGCAGAT GAGTTTGTTA CTGGCACTCA GGGCAAAGGC 
AAACGTCCTG GTGAGTCCAG CAGTCCTACT GTGGGAGGGG CACCTAAACG CAGGCGCTGC 
ATGTCTCCAT TGCTTCGGCC TGGACGGGCA TATACACCTC CTAGAACACC ATCCAGAACT 
CCCGATAACA ATCACTTGGA ATTGGAAAAC CATATCACCA ATCATCTCGA GCCAAACTGC 
GACTCGGACA GCGATATAAA TCCTGTGCCG GAGTCTGAAG TGATCCAGCA AAGCAACCAT 
CTCCAGACAG AAGAGGTTGA GAACCAGCAG GACTGCGTGC AGGAGAATGG CCAGTCCAGT 
GACAGTGAGC TGTCTTTGGG AAGCGAGGGG GAAGAGGAGG CCCCGCACCG CTACCAGTAC 
CCCTGCCAGC TGAAGAAGAT CAGAAACCAG GAGAGCCAGG AGCTCAACTC TGAACTCCGA 
GTGCTCATCA CCAAGGAGAT CAGGAAACCT GGAAGACGTT ATGAGAAAAT CTTCTACCTT 
CTCAAGCAAA TCCAGGGCAG TTTGGAAACG CGCCTGATCT TCTTGCAGAG CATAATCAAA 
GAGGCTGCAA GATTTAAGAA GAGGGTCTTA ATCGAGCAGC TGGAGATTTT CATAGAGGAG 
ATTCACTTAA GAGCCAACGG CATGAATCAT CTGGACAGTT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001119900.1
CDS	331..2895
Translation	MPVLLFLIDTSASMNQRSHLGTSYLDIAKGAVETFLKLRSRDPASRGDRYMLVSFEEAPAGIKAGWKDSHATFMTELRNLQAVGLTSFGQALRTAFDLLNLNRLVSGIDNYGQGRNPFFLEPAIIVAITDGSKLTGSSGVQDELHLPLTTPLPGSELTKEPFRWDQRLFSLVLRVPGHASADPEPVGGVPLDSSPITPMCEVTGGRSYSVFSQRMLNQCLESLVQKIQSGVVINFEKTGPDPSPTEDGPIEVKHGPQVWHSCHKLIYVRPNPKTGVPVGHWPIPESFWPDQNSPTLPPRAAHPHVKFSCVDSEPMVVDKVPFDKYELEPSPLTQYILERKSPHTCWQVFVCNSAKYGELGQPFGYLKASTALNCVNLFVMPYNYPVVLPLLDDLIVVHKFKPPVKWRQSFENYLKTMPPYYIPALRKALRMMGAPNLLADNMEYGLSYSVVSYLKKLSQQAKIEADRVCASVGKKVAPEGGIKLRCRSSALSLANRKDFTQLLQSIMGDGPALPMEANTKEFAGFQLASLNKALKPQGLRNPYDIPRAHLLDQLSRMRRNLLHASICILKGQDQDQLHSVPIAQMGNYQDFLKHCPSPLREADPDQPKRLHTFGNPFKLDKKAMMVDEADEFVTGTQGKGKRPGESSSPTVGGAPKRRRCMSPLLRPGRAYTPPRTPSRTPDNNHLELENHITNHLEPNCDSDSDINPVPESEVIQQSNHLQTEEVENQQDCVQENGQSSDSELSLGSEGEEEAPHRYQYPCQLKKIRNQESQELNSELRVLITKEIRKPGRRYEKIFYLLKQIQGSLETRLIFLQSIIKEAARFKKRVLIEQLEIFIEEIHLRANGMNHLDSF

Target ORF information:

RefSeq Version	NM_001126428.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio integrator complex subunit 6 (ints6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001126428.1

ORF Insert Sequence:

ATGCCCGTGC TACTTTTTCT AATAGACACG TCCGCCTCCA TGAACCAGCG CTCCCATCTG 
GGCACTAGCT ATCTGGACAT AGCGAAGGGC GCAGTTGAGA CTTTCCTGAA GCTGAGAAGC 
AGAGATCCGG CCAGCAGGGG AGACAGATAC ATGTTAGTGA GTTTCGAGGA AGCGCCGGCT 
GGCATTAAGG CTGGATGGAA GGACAGTCAT GCCACTTTTA TGACTGAGCT AAGGAACCTG 
CAAGCAGTTG GACTGACATC GTTTGGCCAA GCTTTAAGGA CAGCTTTTGA TTTGCTCAAT 
CTTAATAGAT TAGTTTCAGG GATAGACAAC TATGGACAGG GTAGAAACCC TTTTTTCTTG 
GAACCTGCTA TCATTGTGGC CATAACTGAT GGCAGCAAGC TGACTGGCAG CTCTGGGGTA 
CAAGATGAGT TACATTTACC GTTAACAACA CCATTACCTG GCAGTGAACT GACCAAAGAG 
CCCTTTCGAT GGGACCAGCG ACTCTTCTCT TTAGTGCTGC GTGTTCCAGG CCATGCCTCT 
GCTGACCCTG AACCAGTGGG TGGAGTTCCA CTCGACTCCT CCCCTATTAC ACCCATGTGT 
GAGGTCACCG GAGGCCGATC ATACAGCGTG TTTTCCCAGA GAATGCTGAA CCAGTGCCTG 
GAGTCTTTGG TACAGAAGAT ACAGAGTGGT GTGGTCATCA ATTTTGAGAA GACTGGACCT 
GATCCTTCTC CTACTGAAGA TGGTCCAATA GAGGTGAAGC ATGGACCTCA AGTATGGCAC 
AGCTGTCATA AATTGATCTA TGTGAGACCC AACCCTAAAA CTGGTGTACC TGTTGGCCAT 
TGGCCTATCC CTGAATCCTT CTGGCCTGAC CAGAACTCTC CTACTTTGCC TCCACGTGCA 
GCTCACCCTC ATGTGAAGTT TTCATGTGTG GATTCGGAGC CCATGGTGGT AGATAAAGTG 
CCCTTCGACA AGTATGAGCT GGAGCCTTCC CCGCTCACCC AGTACATTCT AGAGAGGAAA 
TCACCACATA CCTGCTGGCA GGTTTTTGTG TGTAACAGTG CTAAATATGG AGAACTGGGT 
CAACCGTTTG GATATCTGAA GGCTAGCACA GCTCTCAACT GTGTCAACCT GTTTGTTATG 
CCCTATAACT ATCCTGTGGT GCTTCCATTG CTTGATGACT TAATTGTTGT GCATAAGTTC 
AAGCCTCCAG TGAAGTGGCG ACAGTCTTTT GAAAATTATC TTAAAACAAT GCCCCCCTAC 
TACATCCCAG CCCTGCGGAA AGCATTAAGA ATGATGGGGG CTCCAAACCT GTTAGCAGAC 
AACATGGAAT ATGGCCTCAG CTACAGTGTT GTGTCTTATC TTAAAAAGCT CAGTCAGCAG 
GCGAAGATCG AGGCAGACCG AGTTTGTGCT TCAGTGGGAA AAAAAGTGGC ACCAGAAGGT 
GGAATTAAAC TTCGTTGTAG GAGCTCTGCT CTATCCCTGG CAAACAGGAA GGATTTCACA 
CAGCTTCTGC AGAGCATCAT GGGAGATGGA CCAGCACTTC CAATGGAGGC AAACACCAAG 
GAGTTTGCTG GCTTTCAGCT GGCTTCCTTG AATAAAGCAT TAAAACCACA GGGCTTGCGC 
AACCCTTACG ATATCCCAAG AGCTCATCTT CTGGACCAGC TGAGCCGCAT GAGGAGGAAC 
CTTCTGCATG CCAGTATCTG TATTCTCAAA GGGCAAGATC AAGATCAGCT TCACAGTGTG 
CCTATAGCTC AGATGGGCAA CTATCAGGAC TTCTTGAAGC ATTGCCCATC ACCTCTGAGA 
GAGGCAGACC CTGATCAGCC CAAACGTCTG CACACCTTTG GTAACCCCTT TAAACTGGAC 
AAGAAGGCCA TGATGGTGGA TGAGGCAGAT GAGTTTGTTA CTGGCACTCA GGGCAAAGGC 
AAACGTCCTG GTGAGTCCAG CAGTCCTACT GTGGGAGGGG CACCTAAACG CAGGCGCTGC 
ATGTCTCCAT TGCTTCGGCC TGGACGGGCA TATACACCTC CTAGAACACC ATCCAGAACT 
CCCGATAACA ATCACTTGGA ATTGGAAAAC CATATCACCA ATCATCTCGA GCCAAACTGC 
GACTCGGACA GCGATATAAA TCCTGTGCCG GAGTCTGAAG TGATCCAGCA AAGCAACCAT 
CTCCAGACAG AAGAGGTTGA GAACCAGCAG GACTGCGTGC AGGAGAATGG CCAGTCCAGT 
GACAGTGAGC TGTCTTTGGG AAGCGAGGGG GAAGAGGAGG CCCCGCACCG CTACCAGTAC 
CCCTGCCAGC TGAAGAAGAT CAGAAACCAG GAGAGCCAGG AGCTCAACTC TGAACTCCGA 
GTGCTCATCA CCAAGGAGAT CAGGAAACCT GGAAGACGTT ATGAGAAAAT CTTCTACCTT 
CTCAAGCAAA TCCAGGGCAG TTTGGAAACG CGCCTGATCT TCTTGCAGAG CATAATCAAA 
GAGGCTGCAA GATTTAAGAA GAGGGTCTTA ATCGAGCAGC TGGAGATTTT CATAGAGGAG 
ATTCACTTAA GAGCCAACGG CATGAATCAT CTGGACAGTT TCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

The integrator complex subunit 6 (Ints6) confines the dorsal organizer in vertebrate embryogenesis.
PLoS genetics9(10)e1003822(2013 Oct)
Kapp LD,Abrams EW,Marlow FL,Mullins MC