bloc1s1 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	bloc1s1
Entrez Gene ID	556597
Full Name	biogenesis of lysosomal organelles complex-1, subunit 1
Synonyms	si:dkey-102c8.4
General protein information	Preferred Names biogenesis of lysosomal organelles complex-1, subunit 1 Names biogenesis of lysosome-related organelles complex 1 subunit 1 biogenesis of lysosome-related organelles complex 1 subunit 1-like
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001044350.2	NP_001037815.1	biogenesis of lysosome-related organelles complex 1 subunit 1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Bloc1s1	NP_056555.2
Xenopus tropicalis (tropical clawed frog)	bloc1s1	NP_001072249.1
Danio rerio (zebrafish)	LOC556597	NP_001037815.1
Drosophila melanogaster (fruit fly)	blos1	NP_725401.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001887	XP_321175.4
	BLOC1S1	XP_001095809.2
Homo sapiens (human)	BLOC1S1	NP_001478.2
Pan troglodytes (chimpanzee)	BLOC1S1	XP_509120.1
Bos taurus (cattle)	BLOC1S1	NP_001069830.1
Rattus norvegicus (Norway rat)	Bloc1s1	NP_001099411.2
Caenorhabditis elegans (roundworm)	CELE_T20G5.10	NP_499262.1

Gene Ontology
Bibliography

Related articles in PubMed

Development of the Swimbladder Surfactant System and Biogenesis of Lysosome-Related Organelles Is Regulated by BLOS1 in Zebrafish.
Chen T, Song G, Yang H, Mao L, Cui Z, Huang K
Genetics(2018 Jan)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Genetic characterization and in vivo image analysis of novel zebrafish Danio rerio pigment mutants.
Hsu CC, Pai WY, Lai CY, Lu MW, Her GM
Journal of fish biology82(5)1671-83(2013 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following bloc1s1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the bloc1s1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa34468	NM_001044350.2 Latest version!	Danio rerio biogenesis of lysosomal organelles complex-1, subunit 1 (bloc1s1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

bloc1s1 ( NM_001044350.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001037815.1 Danio rerio biogenesis of lysosomal organelles complex-1, subunit 1 (bloc1s1), mRNA.

Price & Availability↑

CloneID	ODa34468
Clone ID Related Accession (Same CDS sequence)	NM_001044350.2
Accession Version	NM_001044350.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 378bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Danio rerio(zebrafish)
Product	biogenesis of lysosome-related organelles complex 1 subunit 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC135064.1. On Apr 1, 2007 this sequence version replaced NM_001044350.1. ##Evidence-Data-START## Transcript exon combination :: BC135064.1, EH544025.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505373, SAMEA3505390 [ECO:0000348] ##Evidence-Data-END##

ATGCTCTCGC GGTTATTAAA AGAACACCAA GCGAAACAAA ACGAAAGGAA GGAGCTGCAA 
GAAAGACGAA GAAGAGAAGC AATAGCAGCT GCTACATGTT TAACTGAAGC TCTGGTGGAT 
CATCTCAATG TAGGTGTGGC GCAGGCCTAC GTCAATCAAC GCAAGCTGGA CCATGAGGTG 
AAGACACTGC AGGTTCAGGC CGGTCAGTTT GCCAAGCAGA CGGCACAGTG GATCAACATG 
GTGGAGAACT TCAACCAGGC TTTAAAGGAA ATCGGAGACG TGGAGAATTG GGCGCGCAGT 
ATCGAGATGG ACATGCGGAC GATTGCCACG GCTCTGGAGT ATGTGCATAA AGGCCCGGTC 
CAGCCGGCAT CCACATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001037815.1
CDS	68..445
Translation	MLSRLLKEHQAKQNERKELQERRRREAIAAATCLTEALVDHLNVGVAQAYVNQRKLDHEVKTLQVQAGQFAKQTAQWINMVENFNQALKEIGDVENWARSIEMDMRTIATALEYVHKGPVQPAST

Target ORF information:

RefSeq Version	NM_001044350.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio biogenesis of lysosomal organelles complex-1, subunit 1 (bloc1s1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001044350.2

ORF Insert Sequence:

ATGCTCTCGC GGTTATTAAA AGAACACCAA GCGAAACAAA ACGAAAGGAA GGAGCTGCAA 
GAAAGACGAA GAAGAGAAGC AATAGCAGCT GCTACATGTT TAACTGAAGC TCTGGTGGAT 
CATCTCAATG TAGGTGTGGC GCAGGCCTAC GTCAATCAAC GCAAGCTGGA CCATGAGGTG 
AAGACACTGC AGGTTCAGGC CGGTCAGTTT GCCAAGCAGA CGGCACAGTG GATCAACATG 
GTGGAGAACT TCAACCAGGC TTTAAAGGAA ATCGGAGACG TGGAGAATTG GGCGCGCAGT 
ATCGAGATGG ACATGCGGAC GATTGCCACG GCTCTGGAGT ATGTGCATAA AGGCCCGGTC 
CAGCCGGCAT CCACATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Development of the Swimbladder Surfactant System and Biogenesis of Lysosome-Related Organelles Is Regulated by BLOS1 in Zebrafish.
Genetics(2018 Jan)
Chen T,Song G,Yang H,Mao L,Cui Z,Huang K

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Genetic characterization and in vivo image analysis of novel zebrafish Danio rerio pigment mutants.
Journal of fish biology82(5)1671-83(2013 May)
Hsu CC,Pai WY,Lai CY,Lu MW,Her GM