homer2 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	homer2
Entrez Gene ID	553661
Full Name	homer scaffolding protein 2
Synonyms	zgc:111960
General protein information	Preferred Names homer scaffolding protein 2 Names homer protein homolog 2 homer homolog 2 zmp:0000000677
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001020634.1	NP_001018470.1	homer protein homolog 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	HOMER2	XP_510553.3
Mus musculus (house mouse)	Homer2	NP_036113.1
Danio rerio (zebrafish)	homer2	NP_001018470.1
Homo sapiens (human)	HOMER2	NP_955362.1
Bos taurus (cattle)	HOMER2	NP_001068935.1
Rattus norvegicus (Norway rat)	Homer2	NP_445761.1
Drosophila melanogaster (fruit fly)	homer	NP_477396.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP010076	XP_319234.3
	HOMER2	XP_001082200.2
Canis lupus familiaris (dog)	HOMER2	XP_005618788.1
Gallus gallus (chicken)	HOMER2	XP_413836.4
Xenopus tropicalis (tropical clawed frog)	homer2	NP_001016054.1

Gene Ontology
Bibliography

Related articles in PubMed

Evolution of complexity in the zebrafish synapse proteome.
Bay?s ?, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 Mar)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

HOMER2, a stereociliary scaffolding protein, is essential for normal hearing in humans and mice.
Azaiez H, Decker AR, Booth KT, Simpson AC, Shearer AE, Huygen PL, Bu F, Hildebrand MS, Ranum PT, Shibata SB, Turner A, Zhang Y, Kimberling WJ, Cornell RA, Smith RJ
PLoS genetics11(3)e1005137(2015 Mar)

Profiling, Bioinformatic, and Functional Data on the Developing Olfactory/GnRH System Reveal Cellular and Molecular Pathways Essential for This Process and Potentially Relevant for the Kallmann Syndrome.
Garaffo G, Provero P, Molineris I, Pinciroli P, Peano C, Battaglia C, Tomaiuolo D, Etzion T, Gothilf Y, Santoro M, Merlo GR
Frontiers in endocrinology4203(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following homer2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the homer2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa01172	NM_001020634.1 Latest version!	Danio rerio homer scaffold protein 2 (homer2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

homer2 ( NM_001020634.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001018470.1 Danio rerio homer scaffold protein 2 (homer2), mRNA.

Price & Availability↑

CloneID	ODa01172
Clone ID Related Accession (Same CDS sequence)	NM_001020634.1
Accession Version	NM_001020634.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 945bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-26
Organism	Danio rerio(zebrafish)
Product	homer protein homolog 2
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC095619.1. ##Evidence-Data-START## Transcript exon combination :: BC095619.1 [ECO:0000332] ##Evidence-Data-END##

ATGGGGGAGC AGCCGATCTT CACCACCAGG GCTCATGTCT TCCAGATCGA CCCCACGACC 
AAGAAGAACT GGGTTCCCGC CAGTAAACAG GCCGTTACGG TCTCCTACTT CTACGACAGC 
GCACGCAACA GCTACCGCAT CATCAGCGTA GACGGAACAA AGGTGATCAT CAACAGCACC 
ATCACACCCA ACATGAACTT CACTAAAACC TCTCAGAAGT TCGGGCAGTG GGCCGACAGC 
AGAGCCAACA CGGTGTTCGG CCTCGGGTTC GCCTCCGAGC AGCAGCTGTC CAAGTTCGCA 
GAGAAGTTCC TGGAGGTCAA AGAGGCAGCA AAACTGGCCA GAGAGAAGTC TCAGGACAAG 
ATGGAGACGT CGAGCGATCA GTCACAGGAG TCTGGGCGAG ACACTCCGTC AGGGAATCAG 
CCGTCCAGCA TCAACGGCAC CGACGACGAG AAGATCTCAC ACAGCGGCCC CGAGACGGCA 
GCGCTGAAGG CCGAGAGCTC CGCGGAGAGC CGGAAGACTC AGGCCACGCG GAGCCTGGAG 
GAGAACAACC AGCTGCGCAG CAAGATCGCA GAGCTGGAGC TTCAGTGTAA GGAGCTGAGT 
GTGGAGAGAG AGAGGAACGC TCAGCTCACG GTCCGAATTC AAGAGTTGGA AGCAGATCTG 
CAGGACAAAC AACAGGAGCT GGAGAATCTG CGCAAACAGG CCGAGATAAT CCCACAGCTG 
ATGGCGGAGT GTGAGAGCCT CAGCGGCAAA CTACAGGCGG CGGAGCTCTC CAGCAGTGGT 
CTGCGTGAGC GTGTGGAGCT CCTGCAGGGC GAGGCGCAGC ACCGGCAGCA GCAGCAGAAC 
AGCCTGAAGA CGGAGCTCAA ACTCCTGATG GAGCAGCTGG ACGGCAAGAT CGACGAGCTG 
CACGAGGTCC GACAGGGCAT CTCCAAACTC GGCATCGACA ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001018470.1
CDS	104..1048
Translation	MGEQPIFTTRAHVFQIDPTTKKNWVPASKQAVTVSYFYDSARNSYRIISVDGTKVIINSTITPNMNFTKTSQKFGQWADSRANTVFGLGFASEQQLSKFAEKFLEVKEAAKLAREKSQDKMETSSDQSQESGRDTPSGNQPSSINGTDDEKISHSGPETAALKAESSAESRKTQATRSLEENNQLRSKIAELELQCKELSVERERNAQLTVRIQELEADLQDKQQELENLRKQAEIIPQLMAECESLSGKLQAAELSSSGLRERVELLQGEAQHRQQQQNSLKTELKLLMEQLDGKIDELHEVRQGISKLGIDN

Target ORF information:

RefSeq Version	NM_001020634.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio homer scaffold protein 2 (homer2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001020634.1

ORF Insert Sequence:

ATGGGGGAGC AGCCGATCTT CACCACCAGG GCTCATGTCT TCCAGATCGA CCCCACGACC 
AAGAAGAACT GGGTTCCCGC CAGTAAACAG GCCGTTACGG TCTCCTACTT CTACGACAGC 
GCACGCAACA GCTACCGCAT CATCAGCGTA GACGGAACAA AGGTGATCAT CAACAGCACC 
ATCACACCCA ACATGAACTT CACTAAAACC TCTCAGAAGT TCGGGCAGTG GGCCGACAGC 
AGAGCCAACA CGGTGTTCGG CCTCGGGTTC GCCTCCGAGC AGCAGCTGTC CAAGTTCGCA 
GAGAAGTTCC TGGAGGTCAA AGAGGCAGCA AAACTGGCCA GAGAGAAGTC TCAGGACAAG 
ATGGAGACGT CGAGCGATCA GTCACAGGAG TCTGGGCGAG ACACTCCGTC AGGGAATCAG 
CCGTCCAGCA TCAACGGCAC CGACGACGAG AAGATCTCAC ACAGCGGCCC CGAGACGGCA 
GCGCTGAAGG CCGAGAGCTC CGCGGAGAGC CGGAAGACTC AGGCCACGCG GAGCCTGGAG 
GAGAACAACC AGCTGCGCAG CAAGATCGCA GAGCTGGAGC TTCAGTGTAA GGAGCTGAGT 
GTGGAGAGAG AGAGGAACGC TCAGCTCACG GTCCGAATTC AAGAGTTGGA AGCAGATCTG 
CAGGACAAAC AACAGGAGCT GGAGAATCTG CGCAAACAGG CCGAGATAAT CCCACAGCTG 
ATGGCGGAGT GTGAGAGCCT CAGCGGCAAA CTACAGGCGG CGGAGCTCTC CAGCAGTGGT 
CTGCGTGAGC GTGTGGAGCT CCTGCAGGGC GAGGCGCAGC ACCGGCAGCA GCAGCAGAAC 
AGCCTGAAGA CGGAGCTCAA ACTCCTGATG GAGCAGCTGG ACGGCAAGAT CGACGAGCTG 
CACGAGGTCC GACAGGGCAT CTCCAAACTC GGCATCGACA ACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 Mar)
Bay?s ?,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

HOMER2, a stereociliary scaffolding protein, is essential for normal hearing in humans and mice.
PLoS genetics11(3)e1005137(2015 Mar)
Azaiez H,Decker AR,Booth KT,Simpson AC,Shearer AE,Huygen PL,Bu F,Hildebrand MS,Ranum PT,Shibata SB,Turner A,Zhang Y,Kimberling WJ,Cornell RA,Smith RJ

Profiling, Bioinformatic, and Functional Data on the Developing Olfactory/GnRH System Reveal Cellular and Molecular Pathways Essential for This Process and Potentially Relevant for the Kallmann Syndrome.
Frontiers in endocrinology4203(2013)
Garaffo G,Provero P,Molineris I,Pinciroli P,Peano C,Battaglia C,Tomaiuolo D,Etzion T,Gothilf Y,Santoro M,Merlo GR