sncga cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	sncga
Entrez Gene ID	550229
Full Name	synuclein, gamma a
Synonyms	im:6900770,zgc:110133,zgc:123342
General protein information	Preferred Names synuclein, gamma a Names gamma-synuclein Sncg2 gamma1b-synuclein sncgb zSyn-γ2 zSynB
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
XM_017358741.1	XP_017214230.1	gamma-synuclein isoform X1
NM_001017567.2	NP_001017567.1	gamma-synuclein

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	SNCG	XP_507891.2
	SNCG	XP_001083650.1
Bos taurus (cattle)	SNCG	NP_776611.1
Canis lupus familiaris (dog)	SNCG	XP_005619498.1
Rattus norvegicus (Norway rat)	Sncg	NP_113876.1
Homo sapiens (human)	SNCG	NP_003078.2
Mus musculus (house mouse)	Sncg	NP_035560.1
Gallus gallus (chicken)	SNCG	NP_990003.1
Danio rerio (zebrafish)	sncgb	NP_001018488.1
Danio rerio (zebrafish)	sncga	NP_001017567.1
Xenopus tropicalis (tropical clawed frog)	sncg	NP_001016102.1

Gene Ontology
Bibliography

Related articles in PubMed

Evolution of complexity in the zebrafish synapse proteome.
Bay?s ?, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 Mar)

Melatonin rescues zebrafish embryos from the parkinsonian phenotype restoring the parkin/PINK1/DJ-1/MUL1 network.
D?az-Casado ME, Lima E, Garc?a JA, Doerrier C, Aranda P, Sayed RK, Guerra-Librero A, Escames G, L?pez LC, Acu?a-Castroviejo D
Journal of pineal research61(1)96-107(2016 Aug)

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine induced Parkinson's disease in zebrafish.
Sarath Babu N, Murthy ChL, Kakara S, Sharma R, Brahmendra Swamy CV, Idris MM
Proteomics16(9)1407-20(2016 05)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

Identification of possible downstream genes required for the extension of peripheral axons in primary sensory neurons.
Aoki M, Segawa H, Naito M, Okamoto H
Biochemical and biophysical research communications445(2)357-62(2014 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

cloned three genes, sncb, sncga and sncgb from zebrafish
Title: Recapitulation of zebrafish sncga expression pattern and labeling the habenular complex in transgenic zebrafish using green fluorescent protein reporter gene.

Data show the sequences of zebrafish synucleins are very similar to those of the human proteins. Whole-mount in situ hybridization show that sncga were expressed strongly in the nervous system.
Title: Discovery and characterization of three novel synuclein genes in zebrafish.

The following sncga gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the sncga cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa01520	NM_001017567.2 Latest version!	Danio rerio synuclein, gamma a (sncga), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
ODa01520	XM_017358741.1 Latest version!	Danio rerio synuclein, gamma a (sncga), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

sncga ( NM_001017567.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001017567.1 Danio rerio synuclein, gamma a (sncga), mRNA.

Price & Availability↑

CloneID	ODa01520
Clone ID Related Accession (Same CDS sequence)	XM_017358741.1 , NM_001017567.2
Accession Version	NM_001017567.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 336bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-26
Organism	Danio rerio(zebrafish)
Product	gamma-synuclein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX005174.12, EU368947.1 and BC109422.1. On or before Mar 24, 2009 this sequence version replaced NM_001037433.1, NM_001017567.1. ##Evidence-Data-START## Transcript exon combination :: GDQH01015677.1, GFIL01039118.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATGCAC TGAAGAAGGG ATTCTCCATA GCCAAAGAGG GAGTGGTGGC CGCCGCTGAG 
AAAACCAAGG CCGGGGTGGA GGAGGCAGCC GCCAAAACCA AAGAGGGGGT CATGTATGTA 
GGTACAAAGA CAAAGGAGGG CGTTGCTACA AGTGTAAACA CAGTTGCCCA GAAAACAACT 
GACCAGGCAA ATCTCATGAG TGATACTGCT GTGGCTGGAG CCAATGAGGT GTCAGAGAAG 
GCAGTGGAGG GGCTGGAGAC TATGGTCGCC TCTGCAGGCC TCGTCAAACC GGGGGTGGTG 
AAGCACGAGG AGCAGCCAGC AGACGCCGGG CAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001017567.1
CDS	114..449
Translation	MDALKKGFSIAKEGVVAAAEKTKAGVEEAAAKTKEGVMYVGTKTKEGVATSVNTVAQKTTDQANLMSDTAVAGANEVSEKAVEGLETMVASAGLVKPGVVKHEEQPADAGQ

Target ORF information:

RefSeq Version	NM_001017567.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio synuclein, gamma a (sncga), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001017567.2

ORF Insert Sequence:

ATGGATGCAC TGAAGAAGGG ATTCTCCATA GCCAAAGAGG GAGTGGTGGC CGCCGCTGAG 
AAAACCAAGG CCGGGGTGGA GGAGGCAGCC GCCAAAACCA AAGAGGGGGT CATGTATGTA 
GGTACAAAGA CAAAGGAGGG CGTTGCTACA AGTGTAAACA CAGTTGCCCA GAAAACAACT 
GACCAGGCAA ATCTCATGAG TGATACTGCT GTGGCTGGAG CCAATGAGGT GTCAGAGAAG 
GCAGTGGAGG GGCTGGAGAC TATGGTCGCC TCTGCAGGCC TCGTCAAACC GGGGGTGGTG 
AAGCACGAGG AGCAGCCAGC AGACGCCGGG CAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

sncga ( XM_017358741.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> XP_017214230.1 Danio rerio synuclein, gamma a (sncga), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ODa01520
Clone ID Related Accession (Same CDS sequence)	XM_017358741.1 , NM_001017567.2
Accession Version	XM_017358741.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 336bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-23
Organism	Danio rerio(Zebrafish)
Product	gamma-synuclein isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007124.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATGCAC TGAAGAAGGG ATTCTCCATA GCCAAAGAGG GAGTGGTGGC CGCCGCTGAG 
AAAACCAAGG CCGGGGTGGA GGAGGCAGCC GCCAAAACCA AAGAGGGGGT CATGTATGTA 
GGTACAAAGA CAAAGGAGGG CGTTGCTACA AGTGTAAACA CAGTTGCCCA GAAAACAACT 
GACCAGGCAA ATCTCATGAG TGATACTGCT GTGGCTGGAG CCAATGAGGT GTCAGAGAAG 
GCAGTGGAGG GGCTGGAGAC TATGGTCGCC TCTGCAGGCC TCGTCAAACC GGGGGTGGTG 
AAGCACGAGG AGCAGCCAGC AGACGCCGGG CAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017214230.1
CDS	160..495
Translation	MDALKKGFSIAKEGVVAAAEKTKAGVEEAAAKTKEGVMYVGTKTKEGVATSVNTVAQKTTDQANLMSDTAVAGANEVSEKAVEGLETMVASAGLVKPGVVKHEEQPADAGQ

Target ORF information:

RefSeq Version	XM_017358741.1
Organism	Danio rerio(Zebrafish)
Definition	Danio rerio synuclein, gamma a (sncga), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017358741.1

ORF Insert Sequence:

ATGGATGCAC TGAAGAAGGG ATTCTCCATA GCCAAAGAGG GAGTGGTGGC CGCCGCTGAG 
AAAACCAAGG CCGGGGTGGA GGAGGCAGCC GCCAAAACCA AAGAGGGGGT CATGTATGTA 
GGTACAAAGA CAAAGGAGGG CGTTGCTACA AGTGTAAACA CAGTTGCCCA GAAAACAACT 
GACCAGGCAA ATCTCATGAG TGATACTGCT GTGGCTGGAG CCAATGAGGT GTCAGAGAAG 
GCAGTGGAGG GGCTGGAGAC TATGGTCGCC TCTGCAGGCC TCGTCAAACC GGGGGTGGTG 
AAGCACGAGG AGCAGCCAGC AGACGCCGGG CAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 Mar)
Bay?s ?,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

Melatonin rescues zebrafish embryos from the parkinsonian phenotype restoring the parkin/PINK1/DJ-1/MUL1 network.
Journal of pineal research61(1)96-107(2016 Aug)
D?az-Casado ME,Lima E,Garc?a JA,Doerrier C,Aranda P,Sayed RK,Guerra-Librero A,Escames G,L?pez LC,Acu?a-Castroviejo D

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine induced Parkinson's disease in zebrafish.
Proteomics16(9)1407-20(2016 05)
Sarath Babu N,Murthy ChL,Kakara S,Sharma R,Brahmendra Swamy CV,Idris MM

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

Identification of possible downstream genes required for the extension of peripheral axons in primary sensory neurons.
Biochemical and biophysical research communications445(2)357-62(2014 Mar)
Aoki M,Segawa H,Naito M,Okamoto H