kcnk6 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	kcnk6
Entrez Gene ID	504083
Full Name	potassium channel, subfamily K, member 6
Synonyms	im:7152114,zgc:110418
General protein information	Preferred Names potassium channel, subfamily K, member 6 Names potassium channel subfamily K member 6
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001030074.2	NP_001025245.2	potassium channel subfamily K member 6

Pathways from BioSystems

Homologies

Homo sapiens (human)	KCNK6	NP_004814.1
Bos taurus (cattle)	KCNK6	NP_001192374.1
Mus musculus (house mouse)	Kcnk6	NP_001028697.2
Rattus norvegicus (Norway rat)	Kcnk6	NP_446258.2
Rattus norvegicus (Norway rat)	LOC100909725	XP_003748860.1
Xenopus tropicalis (tropical clawed frog)	kcnk6	NP_001120420.1
Pan troglodytes (chimpanzee)	KCNK6	XP_524250.2
Canis lupus familiaris (dog)	KCNK6	XP_005616683.1
Danio rerio (zebrafish)	kcnk6	NP_001025245.2

Gene Ontology
Bibliography

Related articles in PubMed

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Spatiotemporal resolution of the Ntla transcriptome in axial mesoderm development.
Shestopalov IA, Pitt CL, Chen JK
Nature chemical biology8(3)270-6(2012 Jan)

Identification and functional characterization of zebrafish K(2P)10.1 (TREK2) two-pore-domain K(+) channels.
Gierten J, Hassel D, Schweizer PA, Becker R, Katus HA, Thomas D
Biochimica et biophysica acta1818(1)33-41(2012 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following kcnk6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the kcnk6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa33361	NM_001030074.2 Latest version!	Danio rerio potassium channel, subfamily K, member 6 (kcnk6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

kcnk6 ( NM_001030074.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001025245.2 Danio rerio potassium channel, subfamily K, member 6 (kcnk6), mRNA.

Price & Availability↑

CloneID	ODa33361
Clone ID Related Accession (Same CDS sequence)	NM_001030074.2
Accession Version	NM_001030074.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 948bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-23
Organism	Danio rerio(zebrafish)
Product	potassium channel subfamily K member 6
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CR933839.10 and CU595952.10. On Mar 12, 2011 this sequence version replaced NM_001030074.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: BC096809.1, CN017389.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476818 [ECO:0000348] ##Evidence-Data-END##

ATGTCAACGG CGTTCAGGTC CTGCTTTATG CTCATCGGCT TCATTTTGGC GTACTTCACA 
TATCTGTTAT TGGGAGCGCT TGTTTTCTCA GCCATCGAGC GGCCCATCGA GGAGTCTCTG 
AAAGCGGACC TGAGCTCTCT GAAAGCCGAG TTCCTCAACC TGAGCTGCGT TAACAGCACG 
GCTCTGGAAA CCTTCTTAGA AAGAGTTTTA AAAGCTAATA AATATGGCGT GTCGGTGCTT 
GAAAATGCTT CTCTTCGTAC AAACTGGGAT TTGGCGTCTT CTCTGTTCTT TGCCAACACG 
ATGGTGACGA CAGTGGGATA TGGCCACACG ACGCCACTCT CAGACGCCGG TAAAGCCTTC 
TCCATCGTGT ACGCTCTGAT CGGCGTCCCG TTCACCATGC TGGTGCTGAC AGCGTGTGTG 
CAGCGCCTCA TGCACCCGCT GACCTACAGG CCGATCTCCG CATGCCAGCG GCGGGCCGGT 
CTGCAGCAAC GGTCAGCCAG CGTGGTGCAC TTCATCGTCC TGCTGTTTCT GGTGGTGCTC 
TGCTTCTTCG TGGTGCCGTC GCTGGTGTTC AGCGCCATTG AAGAGACCTG GTCTTTCCTG 
GATGCCTTCT ACTTCTGCTT CATCTCTCTC TGCACTATAG GACTCGGGGA CTTTGTGCCT 
GCGGAAAAAC CAGGACAGAG TCTCAGAGCT TTGTACAAGA TATCAGTCAT GGTCTACCTG 
TTTGTGGGAT TGATGGTGAT GTTCCTGGTC CTCCGCACAT TTCACAAGCT TGCTGATGTT 
TACGGCTGGA CGGCTTTCTT CCACCTGCCG AGCTGCGAGG AAGACGAGGA GGATAAAGAG 
CCAATAATAG AAGCAGGGCC TGAAGACGAT TCGCCGGAGG CTGAGAAGGC CTCAATTAAG 
CCTCTGGATC CCAGCTCGCA AGTCTCCTAC AACTCCATAA ATAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001025245.2
CDS	26..973
Translation	MSTAFRSCFMLIGFILAYFTYLLLGALVFSAIERPIEESLKADLSSLKAEFLNLSCVNSTALETFLERVLKANKYGVSVLENASLRTNWDLASSLFFANTMVTTVGYGHTTPLSDAGKAFSIVYALIGVPFTMLVLTACVQRLMHPLTYRPISACQRRAGLQQRSASVVHFIVLLFLVVLCFFVVPSLVFSAIEETWSFLDAFYFCFISLCTIGLGDFVPAEKPGQSLRALYKISVMVYLFVGLMVMFLVLRTFHKLADVYGWTAFFHLPSCEEDEEDKEPIIEAGPEDDSPEAEKASIKPLDPSSQVSYNSINR

Target ORF information:

RefSeq Version	NM_001030074.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio potassium channel, subfamily K, member 6 (kcnk6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001030074.2

ORF Insert Sequence:

ATGTCAACGG CGTTCAGGTC CTGCTTTATG CTCATCGGCT TCATTTTGGC GTACTTCACA 
TATCTGTTAT TGGGAGCGCT TGTTTTCTCA GCCATCGAGC GGCCCATCGA GGAGTCTCTG 
AAAGCGGACC TGAGCTCTCT GAAAGCCGAG TTCCTCAACC TGAGCTGCGT TAACAGCACG 
GCTCTGGAAA CCTTCTTAGA AAGAGTTTTA AAAGCTAATA AATATGGCGT GTCGGTGCTT 
GAAAATGCTT CTCTTCGTAC AAACTGGGAT TTGGCGTCTT CTCTGTTCTT TGCCAACACG 
ATGGTGACGA CAGTGGGATA TGGCCACACG ACGCCACTCT CAGACGCCGG TAAAGCCTTC 
TCCATCGTGT ACGCTCTGAT CGGCGTCCCG TTCACCATGC TGGTGCTGAC AGCGTGTGTG 
CAGCGCCTCA TGCACCCGCT GACCTACAGG CCGATCTCCG CATGCCAGCG GCGGGCCGGT 
CTGCAGCAAC GGTCAGCCAG CGTGGTGCAC TTCATCGTCC TGCTGTTTCT GGTGGTGCTC 
TGCTTCTTCG TGGTGCCGTC GCTGGTGTTC AGCGCCATTG AAGAGACCTG GTCTTTCCTG 
GATGCCTTCT ACTTCTGCTT CATCTCTCTC TGCACTATAG GACTCGGGGA CTTTGTGCCT 
GCGGAAAAAC CAGGACAGAG TCTCAGAGCT TTGTACAAGA TATCAGTCAT GGTCTACCTG 
TTTGTGGGAT TGATGGTGAT GTTCCTGGTC CTCCGCACAT TTCACAAGCT TGCTGATGTT 
TACGGCTGGA CGGCTTTCTT CCACCTGCCG AGCTGCGAGG AAGACGAGGA GGATAAAGAG 
CCAATAATAG AAGCAGGGCC TGAAGACGAT TCGCCGGAGG CTGAGAAGGC CTCAATTAAG 
CCTCTGGATC CCAGCTCGCA AGTCTCCTAC AACTCCATAA ATAGATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Spatiotemporal resolution of the Ntla transcriptome in axial mesoderm development.
Nature chemical biology8(3)270-6(2012 Jan)
Shestopalov IA,Pitt CL,Chen JK

Identification and functional characterization of zebrafish K(2P)10.1 (TREK2) two-pore-domain K(+) channels.
Biochimica et biophysica acta1818(1)33-41(2012 Jan)
Gierten J,Hassel D,Schweizer PA,Becker R,Katus HA,Thomas D