aqp3a cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	aqp3a
Entrez Gene ID	406777
Full Name	aquaporin 3a
Synonyms	aqp3,wu:fa95h06,wu:fi13e05,zgc:55525
General protein information	Preferred Names aquaporin 3a Names aquaporin 3a aquaporin 3
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_213468.1	NP_998633.1	aquaporin 3a

Pathways from BioSystems

Homologies

	AQP3	XP_001099318.1
Bos taurus (cattle)	AQP3	NP_001073262.1
Mus musculus (house mouse)	Aqp3	NP_057898.2
Danio rerio (zebrafish)	aqp3b	NP_001159593.1
Schizosaccharomyces pombe (fission yeast)	SPAC977.17	NP_592788.1
Pan troglodytes (chimpanzee)	AQP3	XP_520531.1
Canis lupus familiaris (dog)	AQP3	XP_854596.1
Rattus norvegicus (Norway rat)	Aqp3	NP_113891.1
Danio rerio (zebrafish)	aqp3a	NP_998633.1
Xenopus tropicalis (tropical clawed frog)	aqp3	NP_001016845.1
Homo sapiens (human)	AQP3	NP_004916.1
Magnaporthe oryzae (rice blast fungus)	MGG_13615	XP_003717502.1
Gallus gallus (chicken)	AQP3	XP_424500.3
Saccharomyces cerevisiae (baker's yeast)	YFL054C	NP_116601.1

Gene Ontology
Bibliography

Related articles in PubMed

Gain-of-function mutations in Aqp3a influence zebrafish pigment pattern formation through the tissue environment.
Eskova A, Chauvign? F, Maischein HM, Ammelburg M, Cerd? J, N?sslein-Volhard C, Irion U
Development (Cambridge, England)144(11)2059-2069(2017 06)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

Genome Wide Identification, Phylogeny, and Expression of Aquaporin Genes in Common Carp (Cyprinus carpio).
Dong C, Chen L, Feng J, Xu J, Mahboob S, Al-Ghanim K, Li X, Xu P
PloS one11(12)e0166160(2016)

The basal function of teleost prolactin as a key regulator on ion uptake identified with zebrafish knockout models.
Shu Y, Lou Q, Dai Z, Dai X, He J, Hu W, Yin Z
Scientific reports618597(2016 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The mutated amino acid residues in the dominant alleles line the pore surface of Aqp3a and influence pore permeability.
Title: Gain-of-function mutations in Aqp3a influence zebrafish pigment pattern formation through the tissue environment.

Enhanced water and cryoprotectant permeability of porcine oocytes after artificial expression of human and zebrafish aquaporin-3 channels.
Title: Enhanced water and cryoprotectant permeability of porcine oocytes after artificial expression of human and zebrafish aquaporin-3 channels.

The following aqp3a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the aqp3a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa37314	NM_213468.1 Latest version!	Danio rerio aquaporin 3a (aqp3a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

aqp3a ( NM_213468.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_998633.1 Danio rerio aquaporin 3a (aqp3a), mRNA.

Price & Availability↑

CloneID	ODa37314
Clone ID Related Accession (Same CDS sequence)	NM_213468.1
Accession Version	NM_213468.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 891bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-10
Organism	Danio rerio(zebrafish)
Product	aquaporin 3a
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC044188.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC044188.1, EH454835.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGGGTTGGC AGAAAAGCGT TCTGGATAAG CTTGCGCAGA CTTTCCAAAT CCGCAACAAG 
TTACTGCGCC AGGGATTGGC TGAATGCTTA GGAACTCTCA TCCTGGTGAT GTTTGGCTGT 
GGTTCATTGG CCCAGTTGAA ACTAAGCGAA GGTTCTCATG GTCTCTTTCT CACTGCAAAC 
CTTGCTTTTG GGTTTGGTGC TACTCTTGGA ATCTTGGTTT GCGGCCAGGT GTCAGGCGGA 
CATTTAAATC CTGCTGTTAC ATTTGCTCTC TGCCTCTTGG GAAGAGAAAA ATGGAGAAAG 
TTTCCTGTGT ACTTTCTGTT CCAAACACTC GGATCCTTCT TGGGTGCTGC TATTATCTTT 
GCCGAATACC ATGACGCAAT TTATGATTAT GCTGGAGAAT CAAATGAATT GCTTGTACTG 
GGTGAAAAAG AAACAGCTGG GATTTTTGCT ACATACCCAA GCAAATATCT CACCCCCCTA 
AATGGATTTT TTGACCAGGT GATAGGCACA GCATCCCTGA TTGTGTGCAT CCTGGCCATT 
GTGGACCCCT ACAACAACCC GATCCCTCAA GGTCTTGAGG CCTTCACAGT GGGATTCAGC 
GTCCTTATCA TTGGTCTCTC CATGGGCTTC AATTCTGGCT ATGCAGTAAA CCCAGCTCGA 
GATTTTGGAC CTCGTCTTTT TACTGCCATG GCTGGTTGGG GTAGTGAAGT CTTCACAGCC 
AGGGATTATT GGTTTTTGGT GCCCATCTTT GCTCCGTTCA TTGGAGCCGT TATTGGTGTG 
ATTGTGTACC AGCTGATGGT GGGATGGCAT GTGGAAGGAG AGGCACGAGA TAAGAAAGCT 
AAAGCTAGAG AGGAGGTGAT GAACCTCAAT GACGTCGCCA GCAAGGAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_998633.1
CDS	72..962
Translation	MGWQKSVLDKLAQTFQIRNKLLRQGLAECLGTLILVMFGCGSLAQLKLSEGSHGLFLTANLAFGFGATLGILVCGQVSGGHLNPAVTFALCLLGREKWRKFPVYFLFQTLGSFLGAAIIFAEYHDAIYDYAGESNELLVLGEKETAGIFATYPSKYLTPLNGFFDQVIGTASLIVCILAIVDPYNNPIPQGLEAFTVGFSVLIIGLSMGFNSGYAVNPARDFGPRLFTAMAGWGSEVFTARDYWFLVPIFAPFIGAVIGVIVYQLMVGWHVEGEARDKKAKAREEVMNLNDVASKE

Target ORF information:

RefSeq Version	NM_213468.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio aquaporin 3a (aqp3a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_213468.1

ORF Insert Sequence:

ATGGGTTGGC AGAAAAGCGT TCTGGATAAG CTTGCGCAGA CTTTCCAAAT CCGCAACAAG 
TTACTGCGCC AGGGATTGGC TGAATGCTTA GGAACTCTCA TCCTGGTGAT GTTTGGCTGT 
GGTTCATTGG CCCAGTTGAA ACTAAGCGAA GGTTCTCATG GTCTCTTTCT CACTGCAAAC 
CTTGCTTTTG GGTTTGGTGC TACTCTTGGA ATCTTGGTTT GCGGCCAGGT GTCAGGCGGA 
CATTTAAATC CTGCTGTTAC ATTTGCTCTC TGCCTCTTGG GAAGAGAAAA ATGGAGAAAG 
TTTCCTGTGT ACTTTCTGTT CCAAACACTC GGATCCTTCT TGGGTGCTGC TATTATCTTT 
GCCGAATACC ATGACGCAAT TTATGATTAT GCTGGAGAAT CAAATGAATT GCTTGTACTG 
GGTGAAAAAG AAACAGCTGG GATTTTTGCT ACATACCCAA GCAAATATCT CACCCCCCTA 
AATGGATTTT TTGACCAGGT GATAGGCACA GCATCCCTGA TTGTGTGCAT CCTGGCCATT 
GTGGACCCCT ACAACAACCC GATCCCTCAA GGTCTTGAGG CCTTCACAGT GGGATTCAGC 
GTCCTTATCA TTGGTCTCTC CATGGGCTTC AATTCTGGCT ATGCAGTAAA CCCAGCTCGA 
GATTTTGGAC CTCGTCTTTT TACTGCCATG GCTGGTTGGG GTAGTGAAGT CTTCACAGCC 
AGGGATTATT GGTTTTTGGT GCCCATCTTT GCTCCGTTCA TTGGAGCCGT TATTGGTGTG 
ATTGTGTACC AGCTGATGGT GGGATGGCAT GTGGAAGGAG AGGCACGAGA TAAGAAAGCT 
AAAGCTAGAG AGGAGGTGAT GAACCTCAAT GACGTCGCCA GCAAGGAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gain-of-function mutations in Aqp3a influence zebrafish pigment pattern formation through the tissue environment.
Development (Cambridge, England)144(11)2059-2069(2017 06)
Eskova A,Chauvign? F,Maischein HM,Ammelburg M,Cerd? J,N?sslein-Volhard C,Irion U

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

Genome Wide Identification, Phylogeny, and Expression of Aquaporin Genes in Common Carp (Cyprinus carpio).
PloS one11(12)e0166160(2016)
Dong C,Chen L,Feng J,Xu J,Mahboob S,Al-Ghanim K,Li X,Xu P

The basal function of teleost prolactin as a key regulator on ion uptake identified with zebrafish knockout models.
Scientific reports618597(2016 Jan)
Shu Y,Lou Q,Dai Z,Dai X,He J,Hu W,Yin Z