csnk1db cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	csnk1db
Entrez Gene ID	406533
Full Name	casein kinase 1, delta b
Synonyms	csnk1d,wu:fb69b03,wu:fj97a05,zgc:77627
General protein information	Preferred Names casein kinase 1, delta b Names casein kinase I isoform delta-B CKI-delta-B CKId-B
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_213250.1	NP_998415.1	casein kinase I isoform delta-B

Pathways from BioSystems

Homologies

Gallus gallus (chicken)	CSNK1D	XP_415634.3
Saccharomyces cerevisiae (baker's yeast)	HRR25	NP_015120.1
Neurospora crassa	NCU00685	XP_965825.2
Xenopus tropicalis (tropical clawed frog)	csnk1d	NP_989089.1
Mus musculus (house mouse)	Csnk1d	NP_620690.1
Rattus norvegicus (Norway rat)	Csnk1d	NP_620691.2
Homo sapiens (human)	CSNK1D	NP_001884.2
Canis lupus familiaris (dog)	CSNK1D	XP_533137.4
Caenorhabditis elegans (roundworm)	kin-20	NP_872247.4
Kluyveromyces lactis	KLLA0D03168g	XP_453206.1
Eremothecium gossypii	AGOS_AFL091W	NP_985457.1
Magnaporthe oryzae (rice blast fungus)	MGG_02829	XP_003720909.1
Pan troglodytes (chimpanzee)	CSNK1D	XP_001167815.1
Danio rerio (zebrafish)	csnk1db	NP_998415.1
Schizosaccharomyces pombe (fission yeast)	hhp1	NP_595760.1
Arabidopsis thaliana (thale cress)	ckl5	NP_179537.1

Gene Ontology
Bibliography

Related articles in PubMed

Evolution of complexity in the zebrafish synapse proteome.
Bay?s ?, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 Mar)

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I, Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y, Bobe J
BMC genomics17368(2016 05)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

The circadian clock of teleost fish: a comparative analysis reveals distinct fates for duplicated genes.
Toloza-Villalobos J, Arroyo JI, Opazo JC
Journal of molecular evolution80(1)57-64(2015 Jan)

Casein kinase 1? activity: a key element in the zebrafish circadian timing system.
Smadja Storz S, Tovin A, Mracek P, Alon S, Foulkes NS, Gothilf Y
PloS one8(1)e54189(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data indicate that CK1delta inhibition abolishes rhythmic pineal aanat2 mRNA expression.
Title: Casein kinase 1? activity: a key element in the zebrafish circadian timing system.

The phosphorylation of p53 by CK1 is an isoform-specific reaction to the K(221)RQK(224) loop.
Title: Isoform specific phosphorylation of p53 by protein kinase CK1.

The following csnk1db gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the csnk1db cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa37804	NM_213250.1 Latest version!	Danio rerio casein kinase 1, delta b (csnk1db), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

csnk1db ( NM_213250.1 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_998415.1 Danio rerio casein kinase 1, delta b (csnk1db), mRNA.

Price & Availability↑

CloneID	ODa37804
Clone ID Related Accession (Same CDS sequence)	NM_213250.1
Accession Version	NM_213250.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1230bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Danio rerio(zebrafish)
Product	casein kinase I isoform delta-B
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC063953.1. ##Evidence-Data-START## Transcript exon combination :: BC063953.1, EU127825.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGGAGCTAC GAGTTGGAAA CAGATACAGA CTGGGCAGAA AAATTGGAAG TGGATCGTTT 
GGTGACATTT ATTTAGGCAC AGACATTTCA GTTGGAGAGG AAGTGGCCAT CAAACTGGAA 
TGTGTGAAGA CAAAGCATCC ACAGCTCCAT ATCGAGAGCA AGATTTACAA GATGATGCAG 
GGTGGAGTTG GCATCCCTAC CATAAAGTGG TGTGGTGCAG AAGGAGATTA TAACGTGATG 
GTGATGGAGT TGCTCGGCCC CAGTCTGGAG GATCTCTTCA ATTTCTGCTC CAGAAAATTC 
AGCCTGAAAA CTGTCCTCCT GTTGGCCGAT CAGATGATTA GCCGCATAGA GTACATCCAC 
TCCAAGAACT TCATTCACAG AGACGTGAAG CCTGATAACT TTCTGATGGG CTTGGGAAAG 
AAAGGCAACC TTGTCTACAT AATTGACTTC GGTTTGGCAA AGAAATACCG TGATGCCCGA 
ACACACCAGC ACATTCCCTA TCGTGAGAAC AAGAACCTCA CAGGCACTGC GCGCTATGCA 
TCCATCAACA CACATCTTGG CATTGAGCAA TCTCGGAGAG ATGACCTGGA GTCTCTTGGT 
TATGTGCTGA TGTACTTCAA CTTGGGCTCA CTGCCTTGGC AGGGACTGAA AGCCGCCACC 
AAGAGACAGA AGTATGAGCG TATCAGTGAA AAGAAAATGT CCACTCCCAT TGAAGTTCTC 
TGCAAGGGCT ACCCATCTGA ATTTGCCACA TACCTCAACT TCTGCCGGTC ACTGCGATTT 
GATGATAAGC CAGACTACTC GTATTTGAGG CAGCTCTTCA GGAATCTGTT CCACAGACAG 
GGCTTTTCCT ATGACTACGT GTTTGATTGG AACATGCTCA AATTTGGCGC TAACCGTACA 
GCAGAGGAAG CAGATCGTGA GAGGAGAGAG CGGGATGAGC GAATGAGGCA CAGCAGGAAT 
CCTGCTGCTC GAGGGATCCC AGCAGCATCA GGCAGACCCC GGCCTACACA GGACGGTGCT 
CCACCCACCC CACTCACACC CACCTCTCAC ACAGCAAACA CATCCTCACC GAGACCAGTC 
ACTGGGATGG AGCGTGAACG CAAGGTCAGC ATGCGGCTTC ATCGTGGCGC CCCAGTAAAC 
GTGTCATCCT CAGACCTGAC GGGGCGACAA GACACTTCCC GCATGTCCAC ATCACAGAAT 
AGCATTCCTT TCGATCACCA CGGCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_998415.1
CDS	373..1602
Translation	MELRVGNRYRLGRKIGSGSFGDIYLGTDISVGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGANRTAEEADRERRERDERMRHSRNPAARGIPAASGRPRPTQDGAPPTPLTPTSHTANTSSPRPVTGMERERKVSMRLHRGAPVNVSSSDLTGRQDTSRMSTSQNSIPFDHHGK

Target ORF information:

RefSeq Version	NM_213250.1
Organism	Danio rerio(zebrafish)
Definition	Danio rerio casein kinase 1, delta b (csnk1db), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_213250.1

ORF Insert Sequence:

ATGGAGCTAC GAGTTGGAAA CAGATACAGA CTGGGCAGAA AAATTGGAAG TGGATCGTTT 
GGTGACATTT ATTTAGGCAC AGACATTTCA GTTGGAGAGG AAGTGGCCAT CAAACTGGAA 
TGTGTGAAGA CAAAGCATCC ACAGCTCCAT ATCGAGAGCA AGATTTACAA GATGATGCAG 
GGTGGAGTTG GCATCCCTAC CATAAAGTGG TGTGGTGCAG AAGGAGATTA TAACGTGATG 
GTGATGGAGT TGCTCGGCCC CAGTCTGGAG GATCTCTTCA ATTTCTGCTC CAGAAAATTC 
AGCCTGAAAA CTGTCCTCCT GTTGGCCGAT CAGATGATTA GCCGCATAGA GTACATCCAC 
TCCAAGAACT TCATTCACAG AGACGTGAAG CCTGATAACT TTCTGATGGG CTTGGGAAAG 
AAAGGCAACC TTGTCTACAT AATTGACTTC GGTTTGGCAA AGAAATACCG TGATGCCCGA 
ACACACCAGC ACATTCCCTA TCGTGAGAAC AAGAACCTCA CAGGCACTGC GCGCTATGCA 
TCCATCAACA CACATCTTGG CATTGAGCAA TCTCGGAGAG ATGACCTGGA GTCTCTTGGT 
TATGTGCTGA TGTACTTCAA CTTGGGCTCA CTGCCTTGGC AGGGACTGAA AGCCGCCACC 
AAGAGACAGA AGTATGAGCG TATCAGTGAA AAGAAAATGT CCACTCCCAT TGAAGTTCTC 
TGCAAGGGCT ACCCATCTGA ATTTGCCACA TACCTCAACT TCTGCCGGTC ACTGCGATTT 
GATGATAAGC CAGACTACTC GTATTTGAGG CAGCTCTTCA GGAATCTGTT CCACAGACAG 
GGCTTTTCCT ATGACTACGT GTTTGATTGG AACATGCTCA AATTTGGCGC TAACCGTACA 
GCAGAGGAAG CAGATCGTGA GAGGAGAGAG CGGGATGAGC GAATGAGGCA CAGCAGGAAT 
CCTGCTGCTC GAGGGATCCC AGCAGCATCA GGCAGACCCC GGCCTACACA GGACGGTGCT 
CCACCCACCC CACTCACACC CACCTCTCAC ACAGCAAACA CATCCTCACC GAGACCAGTC 
ACTGGGATGG AGCGTGAACG CAAGGTCAGC ATGCGGCTTC ATCGTGGCGC CCCAGTAAAC 
GTGTCATCCT CAGACCTGAC GGGGCGACAA GACACTTCCC GCATGTCCAC ATCACAGAAT 
AGCATTCCTT TCGATCACCA CGGCAAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 Mar)
Bay?s ?,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.
BMC genomics17368(2016 05)
Pasquier J,Cabau C,Nguyen T,Jouanno E,Severac D,Braasch I,Journot L,Pontarotti P,Klopp C,Postlethwait JH,Guiguen Y,Bobe J

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

The circadian clock of teleost fish: a comparative analysis reveals distinct fates for duplicated genes.
Journal of molecular evolution80(1)57-64(2015 Jan)
Toloza-Villalobos J,Arroyo JI,Opazo JC

Casein kinase 1? activity: a key element in the zebrafish circadian timing system.
PloS one8(1)e54189(2013)
Smadja Storz S,Tovin A,Mracek P,Alon S,Foulkes NS,Gothilf Y