kctd12.1 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	kctd12.1
Entrez Gene ID	373865
Full Name	potassium channel tetramerisation domain containing 12.1
Synonyms	lov
General protein information	Preferred Names potassium channel tetramerisation domain containing 12.1 Names BTB/POZ domain-containing protein KCTD12 leftover
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_194405.2	NP_919386.1	BTB/POZ domain-containing protein KCTD12

Pathways from BioSystems

Homologies

Homo sapiens (human)	KCTD12	NP_612453.1
Pan troglodytes (chimpanzee)	KCTD12	XP_001137708.2
Bos taurus (cattle)	KCTD12	XP_005213929.1
Rattus norvegicus (Norway rat)	Kctd12	XP_006252482.1
Danio rerio (zebrafish)	kctd12.1	NP_919386.1
Canis lupus familiaris (dog)	KCTD12	XP_542614.3
	KCTD12	XP_001085454.1
Danio rerio (zebrafish)	kctd12.2	NP_001029191.1
Mus musculus (house mouse)	Kctd12	NP_808383.3
Xenopus tropicalis (tropical clawed frog)	kctd12	NP_001096456.1

Gene Ontology
Bibliography

Related articles in PubMed

Targeted knockout of a chemokine-like gene increases anxiety and fear responses.
Choi JH, Jeong YM, Kim S, Lee B, Ariyasiri K, Kim HT, Jung SH, Hwang KS, Choi TI, Park CO, Huh WK, Carl M, Rosenfeld JA, Raskin S, Ma A, Gecz J, Kim HG, Kim JS, Shin HC, Park DS, Gerlai R, Jamieson BB, Kim JS, Iremonger KJ, Lee SH, Shin HS, Kim CH
Proceedings of the National Academy of Sciences of the United States of America(2018 Jan)

Evolution of complexity in the zebrafish synapse proteome.
Bay?s ?, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 Mar)

Early Commissural Diencephalic Neurons Control Habenular Axon Extension and Targeting.
Beretta CA, Dross N, Guglielmi L, Bankhead P, Soulika M, Gutierrez-Triana JA, Paolini A, Poggi L, Falk J, Ryu S, Kapsimali M, Engel U, Carl M
Current biology : CB27(2)270-278(2017 Jan)

A transcription factor network controls cell migration and fate decisions in the developing zebrafish pineal complex.
Khuansuwan S, Clanton JA, Dean BJ, Patton JG, Gamse JT
Development (Cambridge, England)143(14)2641-50(2016 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Ulk2, which interacts with Kctd12 proteins via a small proline-serine rich domain, promotes branching and elaboration of dendrites
Title: Kctd12 and Ulk2 partner to regulate dendritogenesis and behavior in the habenular nuclei.

ATP-2 interacts with the PLAT domain of lov and is involved in polycystin signaling.
Title: ATP-2 interacts with the PLAT domain of LOV-1 and is involved in Caenorhabditis elegans polycystin signaling.

The following kctd12.1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the kctd12.1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa00250	NM_194405.2 Latest version!	Danio rerio potassium channel tetramerisation domain containing 12.1 (kctd12.1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

kctd12.1 ( NM_194405.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_919386.1 Danio rerio potassium channel tetramerisation domain containing 12.1 (kctd12.1), mRNA.

Price & Availability↑

CloneID	ODa00250
Clone ID Related Accession (Same CDS sequence)	NM_194405.2
Accession Version	NM_194405.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 867bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-26
Organism	Danio rerio(zebrafish)
Product	BTB/POZ domain-containing protein KCTD12
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY120891.1. On Aug 31, 2012 this sequence version replaced NM_194405.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: AY120891.1, AY394957.1 [ECO:0000345] ##Evidence-Data-END##

ATGGCTTTGG CAGACCCCGA GTGTGGAATA TCAAACGGCG CTGATTCCGC GTCTCCGTTT 
TCCGTCATTA TCGAACTTAA CGTGGGAGGA CAGGTGTATG TAACGCGGCA CACCACTTTA 
ATAGCCGTAC CGGACTCTCT GCTGTGGAAC ATGTTCAGTA AGAAAACACC GGCTGAGCTG 
GCGCGGGACA GCAAAGGTCG TTTTTTTCTG GACAGGGACG GCTTTCTTTT CCGCTACATT 
TTAGACTACC TACGGGATCT AAACCTGGTT CTGCCGGACT ATTTTCCAGA GAAAAGTAGA 
TTACAGAGAG AGGCTGAGTT CTTTCAGCTG CGGGACCTTA GCAAGCTCTT GAGTCCCAAA 
ATGAGTAAAG ACAACTCCAT CACTGACGAG ATCTGCCAGA GTGACTCGGA GGAGCCGAGC 
GCGAGCGCGA CTCCGGTGGT CGGACCCGAG ACTTCTCGCA CACTGTCCGT CGCCAGCAGC 
GCACATTCTC CCTCCCTGGA GTCCAGAAAG TCTGGGTACA TCACGGTTGG TTACCGAGGC 
TCGTACACAA TGGGAAGAGA CATACAGACA GACGCCAAAT TCAGGCGGGT CGCGCGGATC 
ACGGTTTGCG GGAAGACTTC TTTGGCAAAG GAGGTGTTTG GAGACACATT GAACGAAAGC 
AGAGACCCGG ACCGGCCCCC AGAGAGGTAC ACCTCGCGCT ATTATCTGAA ATATAATTTC 
CTCGAACAGG CGTTTGACAA ACTGTCAGAG TTTGGCTTCC AGATGGTCGC GTGCAGCTCC 
ACGGGCACGT GCGCGTACTC CAGCAGCGAC CCAAACGAGG ACAAAGTCTG GACAAGCTAC 
ACAGAGTATG TTTTCTGTCG AGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_919386.1
CDS	63..929
Translation	MALADPECGISNGADSASPFSVIIELNVGGQVYVTRHTTLIAVPDSLLWNMFSKKTPAELARDSKGRFFLDRDGFLFRYILDYLRDLNLVLPDYFPEKSRLQREAEFFQLRDLSKLLSPKMSKDNSITDEICQSDSEEPSASATPVVGPETSRTLSVASSAHSPSLESRKSGYITVGYRGSYTMGRDIQTDAKFRRVARITVCGKTSLAKEVFGDTLNESRDPDRPPERYTSRYYLKYNFLEQAFDKLSEFGFQMVACSSTGTCAYSSSDPNEDKVWTSYTEYVFCRE

Target ORF information:

RefSeq Version	NM_194405.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio potassium channel tetramerisation domain containing 12.1 (kctd12.1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_194405.2

ORF Insert Sequence:

ATGGCTTTGG CAGACCCCGA GTGTGGAATA TCAAACGGCG CTGATTCCGC GTCTCCGTTT 
TCCGTCATTA TCGAACTTAA CGTGGGAGGA CAGGTGTATG TAACGCGGCA CACCACTTTA 
ATAGCCGTAC CGGACTCTCT GCTGTGGAAC ATGTTCAGTA AGAAAACACC GGCTGAGCTG 
GCGCGGGACA GCAAAGGTCG TTTTTTTCTG GACAGGGACG GCTTTCTTTT CCGCTACATT 
TTAGACTACC TACGGGATCT AAACCTGGTT CTGCCGGACT ATTTTCCAGA GAAAAGTAGA 
TTACAGAGAG AGGCTGAGTT CTTTCAGCTG CGGGACCTTA GCAAGCTCTT GAGTCCCAAA 
ATGAGTAAAG ACAACTCCAT CACTGACGAG ATCTGCCAGA GTGACTCGGA GGAGCCGAGC 
GCGAGCGCGA CTCCGGTGGT CGGACCCGAG ACTTCTCGCA CACTGTCCGT CGCCAGCAGC 
GCACATTCTC CCTCCCTGGA GTCCAGAAAG TCTGGGTACA TCACGGTTGG TTACCGAGGC 
TCGTACACAA TGGGAAGAGA CATACAGACA GACGCCAAAT TCAGGCGGGT CGCGCGGATC 
ACGGTTTGCG GGAAGACTTC TTTGGCAAAG GAGGTGTTTG GAGACACATT GAACGAAAGC 
AGAGACCCGG ACCGGCCCCC AGAGAGGTAC ACCTCGCGCT ATTATCTGAA ATATAATTTC 
CTCGAACAGG CGTTTGACAA ACTGTCAGAG TTTGGCTTCC AGATGGTCGC GTGCAGCTCC 
ACGGGCACGT GCGCGTACTC CAGCAGCGAC CCAAACGAGG ACAAAGTCTG GACAAGCTAC 
ACAGAGTATG TTTTCTGTCG AGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Targeted knockout of a chemokine-like gene increases anxiety and fear responses.
Proceedings of the National Academy of Sciences of the United States of America(2018 Jan)
Choi JH,Jeong YM,Kim S,Lee B,Ariyasiri K,Kim HT,Jung SH,Hwang KS,Choi TI,Park CO,Huh WK,Carl M,Rosenfeld JA,Raskin S,Ma A,Gecz J,Kim HG,Kim JS,Shin HC,Park DS,Gerlai R,Jamieson BB,Kim JS,Iremonger KJ,Lee SH,Shin HS,Kim CH

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 Mar)
Bay?s ?,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

Early Commissural Diencephalic Neurons Control Habenular Axon Extension and Targeting.
Current biology : CB27(2)270-278(2017 Jan)
Beretta CA,Dross N,Guglielmi L,Bankhead P,Soulika M,Gutierrez-Triana JA,Paolini A,Poggi L,Falk J,Ryu S,Kapsimali M,Engel U,Carl M

A transcription factor network controls cell migration and fate decisions in the developing zebrafish pineal complex.
Development (Cambridge, England)143(14)2641-50(2016 Jul)
Khuansuwan S,Clanton JA,Dean BJ,Patton JG,Gamse JT