atic cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	atic
Entrez Gene ID	140622
Full Name	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Synonyms	cb72,id:ibd1333,wu:fb50b10,wu:fb58a11,wu:fi76g09,wu:fy77g01
General protein information	Preferred Names 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase Names bifunctional purine biosynthesis protein PURH
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001082796.2	NP_001076265.2	bifunctional purine biosynthesis protein PURH

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ATIC	XP_001150761.1
Danio rerio (zebrafish)	atic	NP_001076265.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001423	XP_321707.4
Neurospora crassa	NCU02629	XP_964054.1
Homo sapiens (human)	ATIC	NP_004035.2
Drosophila melanogaster (fruit fly)	CG11089	NP_651305.1
Caenorhabditis elegans (roundworm)	C55F2.1	NP_741452.2
Eremothecium gossypii	AGOS_AFR213C	NP_985760.2
Schizosaccharomyces pombe (fission yeast)	ade10	NP_588027.1
Magnaporthe oryzae (rice blast fungus)	MGG_04435	XP_003713530.1
Bos taurus (cattle)	ATIC	NP_001068722.1
Mus musculus (house mouse)	Atic	NP_080471.2
Rattus norvegicus (Norway rat)	Atic	NP_112276.2
Canis lupus familiaris (dog)	ATIC	XP_545634.2
Gallus gallus (chicken)	ATIC	NP_990509.1
Saccharomyces cerevisiae (baker's yeast)	ADE17	NP_013839.1
Xenopus tropicalis (tropical clawed frog)	atic	NP_001005460.1
	LOC694819	XP_002808069.1
Kluyveromyces lactis	KLLA0F17655g	XP_455873.1
Arabidopsis thaliana (thale cress)	AT2G35040	NP_001189681.1
Oryza sativa (rice)	Os08g0206600	NP_001061240.1

Gene Ontology
Bibliography

Related articles in PubMed

Evolution of complexity in the zebrafish synapse proteome.
Bay?s ?, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 Mar)

RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R
Nature communications68549(2015 Oct)

Integrative analysis of circadian transcriptome and metabolic network reveals the role of de novo purine synthesis in circadian control of cell cycle.
Li Y, Li G, G?rling B, Luy B, Du J, Yan J
PLoS computational biology11(2)e1004086(2015 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following atic gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the atic cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa00619	NM_001082796.2 Latest version!	Danio rerio 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (atic), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

atic ( NM_001082796.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_001076265.2 Danio rerio 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (atic), mRNA.

Price & Availability↑

CloneID	ODa00619
Clone ID Related Accession (Same CDS sequence)	NM_001082796.2
Accession Version	NM_001082796.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1773bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-19
Organism	Danio rerio(zebrafish)
Product	bifunctional purine biosynthesis protein PURH
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC163887.1. On Aug 3, 2008 this sequence version replaced NM_001082796.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC163887.1, BC045385.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END##

ATGGCATCTG AAATAGCATT GCTGAGCGTT TCGGATAAGA CTGGACTGGT GGAGTTCGCC 
AGGCGTCTGG TGTCAGTGGG TCTGTCATTA GTGGCATCAG GAGGAACCGC CAAAACACTC 
AGAGATGCTG GACTTGCAGT CAGGGATGTA TCCGAGATCA CTGGATTCCC TGAGATGCTC 
GGAGGCAGAG TTAAAACCCT TCATCCGGCT GTCCACGGTG GTATTTTGGC CAGAAAAACT 
CCATCTGATA ATGCTGATAT GGAAAAACTT GGGTTTAGTC TTGTCAGAGT GGCCGTGTGC 
AACCTTTACC CGTTTGTGAA GACCGTTTCA TCCCCTGGTG TGACTGTGGA AGACGCTGTT 
GAGCAGATTG ACATCGGTGG TGTTACTCTT CTTCGAGCGG CAGCTAAGAA CCACGCTAGA 
GTCACCGTCG TCTGCGATCC ATCCGACTAC AATGTTGTGG CCAAGGAAAT GGAGACCTCT 
GAAATCCACG ACACCACAAT GGAAACCCGC AAAACTCTCG CGCTCAAGGC CTTCACGCAC 
ACCGCTCAGT ACGACGAGGC CATCTCTGAT TACTTCAGAC GTGAATACAG TCGAGGAGTT 
TCCCAGCTTC CTCTGCGTTA CGGGATGAAC CCACATCAAG CACCAGCTCA GCTCTACACT 
ACACGACCAG CACTTCCGCT CGCAGTCCTG AATGGATCTC CTGGCTTCAT TAATCTGTGT 
GATGCTCTGA ACGCCTGGCA GCTGGTCAGA GAGTTGAAGA AGGCTCTCGG TTTGCCAGCC 
GCCACTTCAT TTAAACACGT CAGTCCTGCA GGAGCTGCTG TCGGCGTCCC GTTGAGTGAA 
GACGAGGCCA AAGTGTGTAT GGTGAATGAC ATGCTGCAGG ATCTCACTCC TCTCGCCACT 
GCGTACGCCA GAGCCAGAGG ATCTGACAGA ATGTCCTCTT TTGGAGACTT CATCGCTTTG 
TCTGATGTCT GTGATGTTCC CACTGCCAAG ATCATCTCCA GAGAGGTGTC TGATGGTATT 
GTTGCTCCTG GTTATGAAGA GGATGCCCTG CGAATTCTGT CCAAAAAGAA GAATGGAAAC 
TATTGTGTTC TTAAGATGGA TCCTGAATAT GAACCTGATG AGGAAGAGGT GAGGGTGCTG 
TTTGGTTTAC ATCTCAAACA GAAGAGGAAT GGAGCAGTCA TTGATAAAGA GCTCTTCAGC 
AACATTGTGT CAAAGGGAAA GCTCTCTGAG AGTGCTCTGC GAGACCTCAT CGTTGCCTCC 
ATCGCTGTAA AGTACACCCA GTCTAACTCT GTGTGTTATG CTAAGGATGG GCAGGTGATT 
GGCATCGGAG CTGGGCAGCA GTCTCGTATC CACTGCACCC GGCTGGCAGG AGACAAGGCT 
GATAACTGGT GGCTCAGGCA CCATCCAGGA GTGCTCAGTA TGAGGTTTCG CAGCGGAGTG 
AAGCGTGCAG AGATGGCTAA TGCTATTGAT CAGTATGTCA GCGGCACAGT TGGAGAGGGA 
CCAGATAAGG AGGTCTGGAA GGGTCTGTTT GAGGAGGTCC CTGAGCCTCT GTCAGAGGTG 
GAGAAGAAGA ACTGGATCAG TTCTCTGCAG GCTGTGGCCC TCAGCTCTGA TGCTTTCTTC 
CCCTTTAGGG ACAATGTTGA CCGTGCCAAA CAGAGCGGTG TGGAGTATAT CGCTGCTCCG 
TCTGGCTCTA CTGCTGATGA AGTGGTTGTC AAGGCCTGCA ATGAGCTGGG AATTACCCTG 
GTACACACCA ACATTCGTCT CTTCCATCAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001076265.2
CDS	45..1817
Translation	MASEIALLSVSDKTGLVEFARRLVSVGLSLVASGGTAKTLRDAGLAVRDVSEITGFPEMLGGRVKTLHPAVHGGILARKTPSDNADMEKLGFSLVRVAVCNLYPFVKTVSSPGVTVEDAVEQIDIGGVTLLRAAAKNHARVTVVCDPSDYNVVAKEMETSEIHDTTMETRKTLALKAFTHTAQYDEAISDYFRREYSRGVSQLPLRYGMNPHQAPAQLYTTRPALPLAVLNGSPGFINLCDALNAWQLVRELKKALGLPAATSFKHVSPAGAAVGVPLSEDEAKVCMVNDMLQDLTPLATAYARARGSDRMSSFGDFIALSDVCDVPTAKIISREVSDGIVAPGYEEDALRILSKKKNGNYCVLKMDPEYEPDEEEVRVLFGLHLKQKRNGAVIDKELFSNIVSKGKLSESALRDLIVASIAVKYTQSNSVCYAKDGQVIGIGAGQQSRIHCTRLAGDKADNWWLRHHPGVLSMRFRSGVKRAEMANAIDQYVSGTVGEGPDKEVWKGLFEEVPEPLSEVEKKNWISSLQAVALSSDAFFPFRDNVDRAKQSGVEYIAAPSGSTADEVVVKACNELGITLVHTNIRLFHH

Target ORF information:

RefSeq Version	NM_001082796.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (atic), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001082796.2

ORF Insert Sequence:

ATGGCATCTG AAATAGCATT GCTGAGCGTT TCGGATAAGA CTGGACTGGT GGAGTTCGCC 
AGGCGTCTGG TGTCAGTGGG TCTGTCATTA GTGGCATCAG GAGGAACCGC CAAAACACTC 
AGAGATGCTG GACTTGCAGT CAGGGATGTA TCCGAGATCA CTGGATTCCC TGAGATGCTC 
GGAGGCAGAG TTAAAACCCT TCATCCGGCT GTCCACGGTG GTATTTTGGC CAGAAAAACT 
CCATCTGATA ATGCTGATAT GGAAAAACTT GGGTTTAGTC TTGTCAGAGT GGCCGTGTGC 
AACCTTTACC CGTTTGTGAA GACCGTTTCA TCCCCTGGTG TGACTGTGGA AGACGCTGTT 
GAGCAGATTG ACATCGGTGG TGTTACTCTT CTTCGAGCGG CAGCTAAGAA CCACGCTAGA 
GTCACCGTCG TCTGCGATCC ATCCGACTAC AATGTTGTGG CCAAGGAAAT GGAGACCTCT 
GAAATCCACG ACACCACAAT GGAAACCCGC AAAACTCTCG CGCTCAAGGC CTTCACGCAC 
ACCGCTCAGT ACGACGAGGC CATCTCTGAT TACTTCAGAC GTGAATACAG TCGAGGAGTT 
TCCCAGCTTC CTCTGCGTTA CGGGATGAAC CCACATCAAG CACCAGCTCA GCTCTACACT 
ACACGACCAG CACTTCCGCT CGCAGTCCTG AATGGATCTC CTGGCTTCAT TAATCTGTGT 
GATGCTCTGA ACGCCTGGCA GCTGGTCAGA GAGTTGAAGA AGGCTCTCGG TTTGCCAGCC 
GCCACTTCAT TTAAACACGT CAGTCCTGCA GGAGCTGCTG TCGGCGTCCC GTTGAGTGAA 
GACGAGGCCA AAGTGTGTAT GGTGAATGAC ATGCTGCAGG ATCTCACTCC TCTCGCCACT 
GCGTACGCCA GAGCCAGAGG ATCTGACAGA ATGTCCTCTT TTGGAGACTT CATCGCTTTG 
TCTGATGTCT GTGATGTTCC CACTGCCAAG ATCATCTCCA GAGAGGTGTC TGATGGTATT 
GTTGCTCCTG GTTATGAAGA GGATGCCCTG CGAATTCTGT CCAAAAAGAA GAATGGAAAC 
TATTGTGTTC TTAAGATGGA TCCTGAATAT GAACCTGATG AGGAAGAGGT GAGGGTGCTG 
TTTGGTTTAC ATCTCAAACA GAAGAGGAAT GGAGCAGTCA TTGATAAAGA GCTCTTCAGC 
AACATTGTGT CAAAGGGAAA GCTCTCTGAG AGTGCTCTGC GAGACCTCAT CGTTGCCTCC 
ATCGCTGTAA AGTACACCCA GTCTAACTCT GTGTGTTATG CTAAGGATGG GCAGGTGATT 
GGCATCGGAG CTGGGCAGCA GTCTCGTATC CACTGCACCC GGCTGGCAGG AGACAAGGCT 
GATAACTGGT GGCTCAGGCA CCATCCAGGA GTGCTCAGTA TGAGGTTTCG CAGCGGAGTG 
AAGCGTGCAG AGATGGCTAA TGCTATTGAT CAGTATGTCA GCGGCACAGT TGGAGAGGGA 
CCAGATAAGG AGGTCTGGAA GGGTCTGTTT GAGGAGGTCC CTGAGCCTCT GTCAGAGGTG 
GAGAAGAAGA ACTGGATCAG TTCTCTGCAG GCTGTGGCCC TCAGCTCTGA TGCTTTCTTC 
CCCTTTAGGG ACAATGTTGA CCGTGCCAAA CAGAGCGGTG TGGAGTATAT CGCTGCTCCG 
TCTGGCTCTA CTGCTGATGA AGTGGTTGTC AAGGCCTGCA ATGAGCTGGG AATTACCCTG 
GTACACACCA ACATTCGTCT CTTCCATCAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evolution of complexity in the zebrafish synapse proteome.
Nature communications814613(2017 Mar)
Bay?s ?,Collins MO,Reig-Viader R,Gou G,Goulding D,Izquierdo A,Choudhary JS,Emes RD,Grant SG

RFX transcription factors are essential for hearing in mice.
Nature communications68549(2015 Oct)
Elkon R,Milon B,Morrison L,Shah M,Vijayakumar S,Racherla M,Leitch CC,Silipino L,Hadi S,Weiss-Gayet M,Barras E,Schmid CD,Ait-Lounis A,Barnes A,Song Y,Eisenman DJ,Eliyahu E,Frolenkov GI,Strome SE,Durand B,Zaghloul NA,Jones SM,Reith W,Hertzano R

Integrative analysis of circadian transcriptome and metabolic network reveals the role of de novo purine synthesis in circadian control of cell cycle.
PLoS computational biology11(2)e1004086(2015 Feb)
Li Y,Li G,G?rling B,Luy B,Du J,Yan J