etv6 cDNA ORF clone, Danio rerio(zebrafish)

Gene
Clones
gRNAs

Summary

Gene Symbol	etv6
Entrez Gene ID	114444
Full Name	ets variant 6
Synonyms	id:ibd2308,tel
General protein information	Preferred Names ets variant 6 Names transcription factor ETV6 ets variant gene 6 (TEL oncogene) ztel
Gene Type	protein-coding
Organism	Danio rerio(zebrafish)

mRNA and Protein(s)

mRNA	Protein	Name
NM_131832.2	NP_571907.2	transcription factor ETV6

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Etv6	NP_031987.3
Gallus gallus (chicken)	ETV6	NP_001186202.1
Xenopus tropicalis (tropical clawed frog)	etv6	XP_004913130.1
Pan troglodytes (chimpanzee)	ETV6	XP_528737.2
Canis lupus familiaris (dog)	ETV6	XP_543812.3
Rattus norvegicus (Norway rat)	Etv6	NP_001032430.1
Danio rerio (zebrafish)	etv6	NP_571907.2
Homo sapiens (human)	ETV6	NP_001978.1
Bos taurus (cattle)	ETV6	NP_001015514.2
	ETV6	XP_001083583.1

Gene Ontology
Bibliography

Related articles in PubMed

Functional analysis of truncated forms of ETV6.
Rasighaemi P, Liongue C, Onnebo SM, Ward AC
British journal of haematology171(4)658-62(2015 Nov)

ETV6 (TEL1) regulates embryonic hematopoiesis in zebrafish.
Rasighaemi P, Onnebo SM, Liongue C, Ward AC
Haematologica100(1)23-31(2015 Jan)

ETS factors regulate Vegf-dependent arterial specification.
Wythe JD, Dang LT, Devine WP, Boudreau E, Artap ST, He D, Schachterle W, Stainier DY, Oettgen P, Black BL, Bruneau BG, Fish JE
Developmental cell26(1)45-58(2013 Jul)

Alternative TEL-JAK2 fusions associated with T-cell acute lymphoblastic leukemia and atypical chronic myelogenous leukemia dissected in zebrafish.
Onnebo SM, Rasighaemi P, Kumar J, Liongue C, Ward AC
Haematologica97(12)1895-903(2012 Dec)

An evolutionarily conserved kernel of gata5, gata6, otx2 and prdm1a operates in the formation of endoderm in zebrafish.
Tseng WF, Jang TH, Huang CB, Yuh CH
Developmental biology357(2)541-57(2011 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Dominant-negative truncated ETV6 with deletions of the ETS domain or the PNT domain interfered with repression by full-length ETV6 and affected expression of early hematopoietic and erythroid markers in embryos.
Title: Functional analysis of truncated forms of ETV6.

the transcriptional repressor Tel plays an evolutionarily conserved role in angiogenesis: it is indispensable for the sprouting of human endothelial cells and for normal development of the Danio rerio blood circulatory system
Title: Control of endothelial sprouting by a Tel-CtBP complex.

The following etv6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the etv6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODa03382	NM_131832.2 Latest version!	Danio rerio ETS variant transcription factor 6 (etv6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$258.30 $369.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

etv6 ( NM_131832.2 ) cDNA ORF clone, Danio rerio(zebrafish) -> NP_571907.2 Danio rerio ETS variant transcription factor 6 (etv6), mRNA.

Price & Availability↑

CloneID	ODa03382
Clone ID Related Accession (Same CDS sequence)	NM_131832.2
Accession Version	NM_131832.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1335bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-11
Organism	Danio rerio(zebrafish)
Product	transcription factor ETV6
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC045451.1. On or before Jul 6, 2005 this sequence version replaced XM_696903.1, NM_131832.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC045451.1 [ECO:0000332] ##Evidence-Data-END##

ATGTCCGATT CCCCCTCGCA GCAGCTCATT ATTAAGGAGA GGAGCGCGTT CAGCCCGTCC 
GCCAGTCCAC TGCCAAACTC CACTTCCTCT CCCGGCCATG TGCCGCTCGC ACCCAACACT 
GCCAGAACAG AAGAGGAGAC CAGCAGACTG CCTGCACACC TGCGCATGCA GCCGGTGTTC 
TGGAGCCGTG AGGATGTGTG TGTGTGGCTG CGCTGGGCGG AGAGAGAGTT TGCGCTGAGG 
CCGATATCCA GCGGAAGCTT CCAGATGAAC GGGAAAGCCC TGCTGCTGCT CACCAAAGAG 
GACTTCAGAT ACCGCTCACC ACACTCAGGC GATGTGTTGT ACGAGCTCCT GCAGCACATT 
CTCAAGCAGA GGAAACCACA CGCGTATTTT CCCATCAGCC CCTTCCACAC ACTGAATGAC 
ACGCCACCAC AGCAGCACAA ACACGAAGAA ACGGTACGCC GGCCAGTGCG AGGGACAGAC 
TCTGCTGTCT CCCTGCAGCC GCCCACAATA GAGCTGCGCC ACCGCTCACG CTCGCCTCTC 
CATCATCATC ATCACCACCT TCATCATCTC CATCACCGGC CCACATCAGC CGAGGACCCG 
CAGCAGATGT CTGCACCGCT GCCTGACAGC AACCACCACC TGCCTGAGGA TTCATACCCG 
CTGTCTGTAT CTCCTGCTGC CGCCGCTAAT GGGCACTGCC CTGCTCGGGA CGCCCCGCCG 
CCTGCCAGCC CCGGCCCGGA GGAGAGCGCC CCGCCGCGGG TCATCCAGCT GCTGCCTAGC 
GCAATCATGC ACCCGCTGAT GCTGAGCCCG GCCCGTGGCC CACCAGCACC TCCGCAGAAC 
GGCCGCGAGA GTAAAGCGCA GCATCAGCAC AGCGGCAGCG GAGGACACTA CAGCCTCAGT 
GCACAGCTCC CTCTGCTGGA CGACAGACAC TACCGCAACC ACATCAGCCT GCAGGATGAG 
CAGGCCACGC CCATGGGACG CATCGCAGAC TGCCGGCTGC TGTGGGATTA CGTCTATCAG 
CTGCTGTCCG ACAGCCGCTA TGAGAACTAC ATCCGCTGGG AGGACCGCGA CACCAAAGTC 
TTCCGCATCA TGGACCCCAA CGGCCTGGCC CGCCTCTGGG GGAACCACAA GAACAGGACC 
AATATGACGT ATGAGAAGAT GTCACGAGCG CTCAGACACT ACTATAAACT CAACATCATC 
CGCAAAGAGC CCGGACAGAG ACTGCTCTCC AGGTTCATGA AGACGCCGGA TGAGATCATG 
AGCGGTCAGA CGGAGCGTCT GGAGCATCTG GAGTCAGACA CAGACGATCA GATCTACGTG 
AAGGAGGAGT GTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_571907.2
CDS	260..1594
Translation	MSDSPSQQLIIKERSAFSPSASPLPNSTSSPGHVPLAPNTARTEEETSRLPAHLRMQPVFWSREDVCVWLRWAEREFALRPISSGSFQMNGKALLLLTKEDFRYRSPHSGDVLYELLQHILKQRKPHAYFPISPFHTLNDTPPQQHKHEETVRRPVRGTDSAVSLQPPTIELRHRSRSPLHHHHHHLHHLHHRPTSAEDPQQMSAPLPDSNHHLPEDSYPLSVSPAAAANGHCPARDAPPPASPGPEESAPPRVIQLLPSAIMHPLMLSPARGPPAPPQNGRESKAQHQHSGSGGHYSLSAQLPLLDDRHYRNHISLQDEQATPMGRIADCRLLWDYVYQLLSDSRYENYIRWEDRDTKVFRIMDPNGLARLWGNHKNRTNMTYEKMSRALRHYYKLNIIRKEPGQRLLSRFMKTPDEIMSGQTERLEHLESDTDDQIYVKEEC

Target ORF information:

RefSeq Version	NM_131832.2
Organism	Danio rerio(zebrafish)
Definition	Danio rerio ETS variant transcription factor 6 (etv6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_131832.2

ORF Insert Sequence:

ATGTCCGATT CCCCCTCGCA GCAGCTCATT ATTAAGGAGA GGAGCGCGTT CAGCCCGTCC 
GCCAGTCCAC TGCCAAACTC CACTTCCTCT CCCGGCCATG TGCCGCTCGC ACCCAACACT 
GCCAGAACAG AAGAGGAGAC CAGCAGACTG CCTGCACACC TGCGCATGCA GCCGGTGTTC 
TGGAGCCGTG AGGATGTGTG TGTGTGGCTG CGCTGGGCGG AGAGAGAGTT TGCGCTGAGG 
CCGATATCCA GCGGAAGCTT CCAGATGAAC GGGAAAGCCC TGCTGCTGCT CACCAAAGAG 
GACTTCAGAT ACCGCTCACC ACACTCAGGC GATGTGTTGT ACGAGCTCCT GCAGCACATT 
CTCAAGCAGA GGAAACCACA CGCGTATTTT CCCATCAGCC CCTTCCACAC ACTGAATGAC 
ACGCCACCAC AGCAGCACAA ACACGAAGAA ACGGTACGCC GGCCAGTGCG AGGGACAGAC 
TCTGCTGTCT CCCTGCAGCC GCCCACAATA GAGCTGCGCC ACCGCTCACG CTCGCCTCTC 
CATCATCATC ATCACCACCT TCATCATCTC CATCACCGGC CCACATCAGC CGAGGACCCG 
CAGCAGATGT CTGCACCGCT GCCTGACAGC AACCACCACC TGCCTGAGGA TTCATACCCG 
CTGTCTGTAT CTCCTGCTGC CGCCGCTAAT GGGCACTGCC CTGCTCGGGA CGCCCCGCCG 
CCTGCCAGCC CCGGCCCGGA GGAGAGCGCC CCGCCGCGGG TCATCCAGCT GCTGCCTAGC 
GCAATCATGC ACCCGCTGAT GCTGAGCCCG GCCCGTGGCC CACCAGCACC TCCGCAGAAC 
GGCCGCGAGA GTAAAGCGCA GCATCAGCAC AGCGGCAGCG GAGGACACTA CAGCCTCAGT 
GCACAGCTCC CTCTGCTGGA CGACAGACAC TACCGCAACC ACATCAGCCT GCAGGATGAG 
CAGGCCACGC CCATGGGACG CATCGCAGAC TGCCGGCTGC TGTGGGATTA CGTCTATCAG 
CTGCTGTCCG ACAGCCGCTA TGAGAACTAC ATCCGCTGGG AGGACCGCGA CACCAAAGTC 
TTCCGCATCA TGGACCCCAA CGGCCTGGCC CGCCTCTGGG GGAACCACAA GAACAGGACC 
AATATGACGT ATGAGAAGAT GTCACGAGCG CTCAGACACT ACTATAAACT CAACATCATC 
CGCAAAGAGC CCGGACAGAG ACTGCTCTCC AGGTTCATGA AGACGCCGGA TGAGATCATG 
AGCGGTCAGA CGGAGCGTCT GGAGCATCTG GAGTCAGACA CAGACGATCA GATCTACGTG 
AAGGAGGAGT GTTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Functional analysis of truncated forms of ETV6.
British journal of haematology171(4)658-62(2015 Nov)
Rasighaemi P,Liongue C,Onnebo SM,Ward AC

ETV6 (TEL1) regulates embryonic hematopoiesis in zebrafish.
Haematologica100(1)23-31(2015 Jan)
Rasighaemi P,Onnebo SM,Liongue C,Ward AC

ETS factors regulate Vegf-dependent arterial specification.
Developmental cell26(1)45-58(2013 Jul)
Wythe JD,Dang LT,Devine WP,Boudreau E,Artap ST,He D,Schachterle W,Stainier DY,Oettgen P,Black BL,Bruneau BG,Fish JE

Alternative TEL-JAK2 fusions associated with T-cell acute lymphoblastic leukemia and atypical chronic myelogenous leukemia dissected in zebrafish.
Haematologica97(12)1895-903(2012 Dec)
Onnebo SM,Rasighaemi P,Kumar J,Liongue C,Ward AC

An evolutionarily conserved kernel of gata5, gata6, otx2 and prdm1a operates in the formation of endoderm in zebrafish.
Developmental biology357(2)541-57(2011 Sep)
Tseng WF,Jang TH,Huang CB,Yuh CH