Tgfb1 cDNA ORF clone, Cavia porcellus(domestic guinea pig)

Gene
Clones
gRNAs

Summary

Gene Symbol	Tgfb1
Entrez Gene ID	100135628
Full Name	transforming growth factor beta 1
Synonyms	TGF-beta
Gene Type	protein-coding
Organism	Cavia porcellus(domestic guinea pig)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001173023.1	NP_001166494.1	transforming growth factor beta-1 proprotein precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Expressions of TGF-?1 and MMP-9 in a guinea pig model of tympanosclerosis: possible role in the pathogenesis of this disorder.
Guo W, Bai X, Han Y, Xu L, Liu W, Zhang G, Li J, Fan Z, Wang H
The Laryngoscope122(9)2037-42(2012 Sep)

[Effects of minimal persistent inflammation on nasal mucosa of experimental allergic rhinitis in guinea pigs].
Lei F, Cui YN, Jiang YP, Kong H, Zhu DD, Dong Z
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery43(7)499-503(2008 Jul)

Spontaneous cytokine gene expression in normal guinea pig blood and tissues.
Scarozza AM, Ramsingh AI, Wicher V, Wicher K
Cytokine10(11)851-9(1998 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

TGF beta is involved in the pathogenesis of tympanosclerosis.
Title: Expressions of TGF-?1 and MMP-9 in a guinea pig model of tympanosclerosis: possible role in the pathogenesis of this disorder.

There was significantly higher expression of TGF-beta1 and MMP-9 in nasal mucosa of experimental allergic rhinitis guinea pigs than in controls.
Title: [Effects of minimal persistent inflammation on nasal mucosa of experimental allergic rhinitis in guinea pigs].

The following Tgfb1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tgfb1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ODo00103	NM_001173023.1 Latest version!	Cavia porcellus transforming growth factor beta 1 (Tgfb1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Tgfb1 ( NM_001173023.1 ) cDNA ORF clone, Cavia porcellus(domestic guinea pig) -> NP_001166494.1 Cavia porcellus transforming growth factor beta 1 (Tgfb1), mRNA.

Price & Availability↑

CloneID	ODo00103
Clone ID Related Accession (Same CDS sequence)	NM_001173023.1
Accession Version	NM_001173023.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1173bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Cavia porcellus(domestic guinea pig)
Product	transforming growth factor beta-1 proprotein precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF191297.1. ##Evidence-Data-START## Transcript exon combination :: AF191297.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1876905, SAMN01831863 [ECO:0000348] ##Evidence-Data-END##

ATGCCTCCCT CTCGGCTGCG GCTCCTGCCG CTCCTGCTAC CGTTACTGTG GCTACTGGTG 
CTGGCACCTG GCCGGCCAGC CTCGGGACTG TCCACCTGCA AGACCATCGA TATGGAGCTG 
GTGAAGCGGA AGCGCATCGA GGCCATCCGC GGTCAGATCC TGTCCAAATT ACGGCTCGCC 
AGCCCCCCGA GCCAGGGGGA TGTACCGCCC GGCCCGCTGC CCGAAGCCGT GCTCGCCCTG 
TACAACAGCA CCCGCGACCG GGTGGCCGGG GAGAGCGCCG AGCCAGAGCC CGAACCCGAG 
CCGGACTACT ATGCCAAGGA GGTGACCCGC GTGTTAATGG TGGACAACAG CCACAATATC 
TATAAAAGCA TTGAGACTGT CGCACACAGT ATATATATGT TCTTCAACAC GTCAGAGCTC 
CGGGAAGCTG TGCCTGACCC TCTGTTGCTG TCTCGGGCAG AGCTGCGAAT GCAGAGACTC 
AAGTTAAATG TGGAACAGCA CGTGGAACTG TACCAAAAAT ACAGCAACAA TTCCTGGCGC 
TACCTCAGCA ACCAGCTCCT GACCCCCAGT GATACCCCAG AGTGGTTGTC CTTTGATGTC 
ACTGGAGTTG TGCGGCAGTG GCTGAGCCAA GGAGAGGAAT TAGAGGGCTT TCGCTTCAGT 
GCTCACTGCT CCTGTGATAG CAAAGATAAC ACGCTCCGCG TGGAAATCAA CGGGATCGGT 
CCCAAACGCC GGGGTGACCT GGCTGCTATT CATGGCATGA ACCGGCCCTT CCTGCTCCTC 
ATGGCCACCC CACTGGAGAG GGCCCAGCAC CTGCACAGCT CCAGACACCG CCGGGGCCTG 
GACACCAACT ATTGCTTCAG CTCCACGGAG AAGAACTGCT GTGTGCGGCA GCTCTACATT 
GACTTCCGCA AGGACCTAGG ATGGAAGTGG ATCCACGAGC CCAAGGGCTA CCATGCCAAC 
TTCTGCCTGG GGCCCTGCCC CTACATTTGG AGCCTGGACA CACAGTACAG CAAGGTCCTG 
GCCCTGTACA ACCAGCACAA CCCCGGCGCT TCGGCGGCGC CTTGCTGTGT GCCGCAGGCG 
TTGGAGCCAC TGCCCATCGT GTACTACGTG GGCCGCAAAG CCAAGGTGGA GCAGCTCTCC 
AACATGATCG TGCGCTCCTG CAAGTGCAGC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001166494.1
CDS	299..1471
Translation	MPPSRLRLLPLLLPLLWLLVLAPGRPASGLSTCKTIDMELVKRKRIEAIRGQILSKLRLASPPSQGDVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEPDYYAKEVTRVLMVDNSHNIYKSIETVAHSIYMFFNTSELREAVPDPLLLSRAELRMQRLKLNVEQHVELYQKYSNNSWRYLSNQLLTPSDTPEWLSFDVTGVVRQWLSQGEELEGFRFSAHCSCDSKDNTLRVEINGIGPKRRGDLAAIHGMNRPFLLLMATPLERAQHLHSSRHRRGLDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKAKVEQLSNMIVRSCKCS

Target ORF information:

RefSeq Version	NM_001173023.1
Organism	Cavia porcellus(domestic guinea pig)
Definition	Cavia porcellus transforming growth factor beta 1 (Tgfb1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001173023.1

ORF Insert Sequence:

ATGCCTCCCT CTCGGCTGCG GCTCCTGCCG CTCCTGCTAC CGTTACTGTG GCTACTGGTG 
CTGGCACCTG GCCGGCCAGC CTCGGGACTG TCCACCTGCA AGACCATCGA TATGGAGCTG 
GTGAAGCGGA AGCGCATCGA GGCCATCCGC GGTCAGATCC TGTCCAAATT ACGGCTCGCC 
AGCCCCCCGA GCCAGGGGGA TGTACCGCCC GGCCCGCTGC CCGAAGCCGT GCTCGCCCTG 
TACAACAGCA CCCGCGACCG GGTGGCCGGG GAGAGCGCCG AGCCAGAGCC CGAACCCGAG 
CCGGACTACT ATGCCAAGGA GGTGACCCGC GTGTTAATGG TGGACAACAG CCACAATATC 
TATAAAAGCA TTGAGACTGT CGCACACAGT ATATATATGT TCTTCAACAC GTCAGAGCTC 
CGGGAAGCTG TGCCTGACCC TCTGTTGCTG TCTCGGGCAG AGCTGCGAAT GCAGAGACTC 
AAGTTAAATG TGGAACAGCA CGTGGAACTG TACCAAAAAT ACAGCAACAA TTCCTGGCGC 
TACCTCAGCA ACCAGCTCCT GACCCCCAGT GATACCCCAG AGTGGTTGTC CTTTGATGTC 
ACTGGAGTTG TGCGGCAGTG GCTGAGCCAA GGAGAGGAAT TAGAGGGCTT TCGCTTCAGT 
GCTCACTGCT CCTGTGATAG CAAAGATAAC ACGCTCCGCG TGGAAATCAA CGGGATCGGT 
CCCAAACGCC GGGGTGACCT GGCTGCTATT CATGGCATGA ACCGGCCCTT CCTGCTCCTC 
ATGGCCACCC CACTGGAGAG GGCCCAGCAC CTGCACAGCT CCAGACACCG CCGGGGCCTG 
GACACCAACT ATTGCTTCAG CTCCACGGAG AAGAACTGCT GTGTGCGGCA GCTCTACATT 
GACTTCCGCA AGGACCTAGG ATGGAAGTGG ATCCACGAGC CCAAGGGCTA CCATGCCAAC 
TTCTGCCTGG GGCCCTGCCC CTACATTTGG AGCCTGGACA CACAGTACAG CAAGGTCCTG 
GCCCTGTACA ACCAGCACAA CCCCGGCGCT TCGGCGGCGC CTTGCTGTGT GCCGCAGGCG 
TTGGAGCCAC TGCCCATCGT GTACTACGTG GGCCGCAAAG CCAAGGTGGA GCAGCTCTCC 
AACATGATCG TGCGCTCCTG CAAGTGCAGC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expressions of TGF-?1 and MMP-9 in a guinea pig model of tympanosclerosis: possible role in the pathogenesis of this disorder.
The Laryngoscope122(9)2037-42(2012 Sep)
Guo W,Bai X,Han Y,Xu L,Liu W,Zhang G,Li J,Fan Z,Wang H

[Effects of minimal persistent inflammation on nasal mucosa of experimental allergic rhinitis in guinea pigs].
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery43(7)499-503(2008 Jul)
Lei F,Cui YN,Jiang YP,Kong H,Zhu DD,Dong Z

Spontaneous cytokine gene expression in normal guinea pig blood and tissues.
Cytokine10(11)851-9(1998 Nov)
Scarozza AM,Ramsingh AI,Wicher V,Wicher K