CCL17 cDNA ORF clone, Canis lupus familiaris(Dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	CCL17
Entrez Gene ID	403586
Full Name	C-C motif chemokine ligand 17
Synonyms	TARC
General protein information	Preferred Names C-C motif chemokine ligand 17 Names C-C motif chemokine 17 CC chemokine TARC chemokine (C-C motif) ligand 17 small-inducible cytokine A17 thymus and activation-regulated chemokine
Gene Type	protein-coding
Organism	Canis lupus familiaris(Dog)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005617215.3	XP_005617272.1	C-C motif chemokine 17 isoform X1
NM_001003051.1	NP_001003051.1	C-C motif chemokine 17 precursor
XM_005617215.2	XP_005617272.1	C-C motif chemokine 17 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Ccl17	NP_476492.1
Pan troglodytes (chimpanzee)	CCL17	XP_523377.2
Bos taurus (cattle)	CCL17	XP_002694838.1
Mus musculus (house mouse)	Ccl17	NP_035462.2
Homo sapiens (human)	CCL17	NP_002978.1
Canis lupus familiaris (dog)	CCL17	NP_001003051.1
	CCL17	NP_001028024.1

Gene Ontology
Bibliography

Related articles in PubMed

Effect of recombinant canine interferon-? on granulocyte-macrophage colony-stimulating factor, transforming growth factor-? and CC chemokine ligand 17 mRNA transcription in a canine keratinocyte cell line (CPEK).
Shibata S, Maeda S, Kondo N, Inoue A, Maeda S, Chimura N, Fukata T
Veterinary dermatology22(1)24-30(2011 Feb)

Identification of the signaling pathway of TNF-?-induced CCL17/TARC transcription in a canine keratinocyte cell line.
Shibata S, Maeda S, Kondo N, Chimura N, Inoue A, Fukata T
Veterinary immunology and immunopathology139(2-4)90-8(2011 Feb)

Augmentation of CCL17 and CCL28 gene expression by TNF-alpha, IL-1beta, or IFN-gamma in cultured canine keratinocytes.
Shibata S, Maeda S, Maeda S, Chimura N, Kondo N, Fukata T
Research in veterinary science88(3)422-6(2010 Jun)

Molecular cloning of canine thymus and activation-regulated chemokine (TARC) gene and its expression in various tissues.
Maeda S, Mizuno T, Yamashita K, Kurata K, Masuda K, Ohno K, Tsujimoto H
The Journal of veterinary medical science63(9)1035-8(2001 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study suggests that interferon-gamma may suppress granulocyte-macrophage colony stimulating factor production from canine keratinocytes, although further studies are required to confirm this.
Title: Effect of recombinant canine interferon-? on granulocyte-macrophage colony-stimulating factor, transforming growth factor-? and CC chemokine ligand 17 mRNA transcription in a canine keratinocyte cell line (CPEK).

The present results suggest that TNF-alpha-induced CCL17 mRNA transcription in canine keratinocytes is positively regulated by p38 but negatively controlled by ERK.
Title: Identification of the signaling pathway of TNF-?-induced CCL17/TARC transcription in a canine keratinocyte cell line.

Inflammatory cytokines are important inducing factors for the production of CCL17 in the lesional skin of dogs with atopic dermatitis. atopic dermatitis.
Title: Augmentation of CCL17 and CCL28 gene expression by TNF-alpha, IL-1beta, or IFN-gamma in cultured canine keratinocytes.

The following CCL17 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCL17 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OCe02911	NM_001003051.1 Latest version!	Canis lupus familiaris C-C motif chemokine ligand 17 (CCL17), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OCe02911	XM_005617215.3 Latest version!	Canis lupus familiaris C-C motif chemokine ligand 17 (CCL17), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
View Old Accession Versions >>
OCe02911	XM_005617215.2	Canis lupus familiaris chemokine (C-C motif) ligand 17 (CCL17), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CCL17 ( NM_001003051.1 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> NP_001003051.1 Canis lupus familiaris C-C motif chemokine ligand 17 (CCL17), mRNA.

Price & Availability↑

CloneID	OCe02911
Clone ID Related Accession (Same CDS sequence)	XM_005617215.3 , NM_001003051.1 , XM_005617215.2
Accession Version	NM_001003051.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-06-06
Organism	Canis lupus familiaris(dog)
Product	C-C motif chemokine 17 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB054642.1. ##Evidence-Data-START## Transcript exon combination :: AB054642.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA103936001, SAMEA103936002 [ECO:0000348] ##Evidence-Data-END##

ATGATTCCCT TGAAGATGCT GCTCCTGGTC ACGCTCCTCC TGGGGGCTTC TCTGCAGGTC 
ACCCATGCAG CTCGAGGCAC CAACGTGGGC CGGGAGTGCT GCCTAGAGTA CTTCAAAGGA 
GCCATTCCTA TCAGCAGGCT GACAAGGTGG TACAAGACTT CAGGGGAGTG TCCCAAGGAT 
GCCATCGTGT TTGTAACTGT CCAAGGCAAG TCCATCTGTT CCGACCCCAA GGACAAGAGG 
GTGAAGAAGG CGGTCAGATA TTTACAAAGA ACCTGGAAGG GAGGGCCCCA AGAGTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003051.1
CDS	1..300
Translation	MIPLKMLLLVTLLLGASLQVTHAARGTNVGRECCLEYFKGAIPISRLTRWYKTSGECPKDAIVFVTVQGKSICSDPKDKRVKKAVRYLQRTWKGGPQES

Target ORF information:

RefSeq Version	NM_001003051.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris C-C motif chemokine ligand 17 (CCL17), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003051.1

ORF Insert Sequence:

ATGATTCCCT TGAAGATGCT GCTCCTGGTC ACGCTCCTCC TGGGGGCTTC TCTGCAGGTC 
ACCCATGCAG CTCGAGGCAC CAACGTGGGC CGGGAGTGCT GCCTAGAGTA CTTCAAAGGA 
GCCATTCCTA TCAGCAGGCT GACAAGGTGG TACAAGACTT CAGGGGAGTG TCCCAAGGAT 
GCCATCGTGT TTGTAACTGT CCAAGGCAAG TCCATCTGTT CCGACCCCAA GGACAAGAGG 
GTGAAGAAGG CGGTCAGATA TTTACAAAGA ACCTGGAAGG GAGGGCCCCA AGAGTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCL17 ( XM_005617215.3 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> XP_005617272.1 Canis lupus familiaris C-C motif chemokine ligand 17 (CCL17), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe02911
Clone ID Related Accession (Same CDS sequence)	XM_005617215.3 , NM_001003051.1 , XM_005617215.2
Accession Version	XM_005617215.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-04
Organism	Canis lupus familiaris(dog)
Product	C-C motif chemokine 17 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006584.3) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Sep 5, 2017 this sequence version replaced XM_005617215.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTCCCT TGAAGATGCT GCTCCTGGTC ACGCTCCTCC TGGGGGCTTC TCTGCAGGTC 
ACCCATGCAG CTCGAGGCAC CAACGTGGGC CGGGAGTGCT GCCTAGAGTA CTTCAAAGGA 
GCCATTCCTA TCAGCAGGCT GACAAGGTGG TACAAGACTT CAGGGGAGTG TCCCAAGGAT 
GCCATCGTGT TTGTAACTGT CCAAGGCAAG TCCATCTGTT CCGACCCCAA GGACAAGAGG 
GTGAAGAAGG CGGTCAGATA TTTACAAAGA ACCTGGAAGG GAGGGCCCCA AGAGTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005617272.1
CDS	3902..4201
Translation	MIPLKMLLLVTLLLGASLQVTHAARGTNVGRECCLEYFKGAIPISRLTRWYKTSGECPKDAIVFVTVQGKSICSDPKDKRVKKAVRYLQRTWKGGPQES

Target ORF information:

RefSeq Version	XM_005617215.3
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris C-C motif chemokine ligand 17 (CCL17), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005617215.3

ORF Insert Sequence:

ATGATTCCCT TGAAGATGCT GCTCCTGGTC ACGCTCCTCC TGGGGGCTTC TCTGCAGGTC 
ACCCATGCAG CTCGAGGCAC CAACGTGGGC CGGGAGTGCT GCCTAGAGTA CTTCAAAGGA 
GCCATTCCTA TCAGCAGGCT GACAAGGTGG TACAAGACTT CAGGGGAGTG TCCCAAGGAT 
GCCATCGTGT TTGTAACTGT CCAAGGCAAG TCCATCTGTT CCGACCCCAA GGACAAGAGG 
GTGAAGAAGG CGGTCAGATA TTTACAAAGA ACCTGGAAGG GAGGGCCCCA AGAGTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CCL17 ( XM_005617215.2 ) cDNA ORF clone, Canis lupus familiaris(Dog) -> XP_005617272.1 Canis lupus familiaris chemokine (C-C motif) ligand 17 (CCL17), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe02911
Clone ID Related Accession (Same CDS sequence)	XM_005617215.3 , NM_001003051.1 , XM_005617215.2
Accession Version	XM_005617215.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-09-16
Organism	Canis lupus familiaris(Dog)
Product	C-C motif chemokine 17 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726050.1) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Sep 17, 2015 this sequence version replaced XM_005617215.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATTCCCT TGAAGATGCT GCTCCTGGTC ACGCTCCTCC TGGGGGCTTC TCTGCAGGTC 
ACCCATGCAG CTCGAGGCAC CAACGTGGGC CGGGAGTGCT GCCTAGAGTA CTTCAAAGGA 
GCCATTCCTA TCAGCAGGCT GACAAGGTGG TACAAGACTT CAGGGGAGTG TCCCAAGGAT 
GCCATCGTGT TTGTAACTGT CCAAGGCAAG TCCATCTGTT CCGACCCCAA GGACAAGAGG 
GTGAAGAAGG CGGTCAGATA TTTACAAAGA ACCTGGAAGG GAGGGCCCCA AGAGTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005617272.1
CDS	3148..3447
Translation	MIPLKMLLLVTLLLGASLQVTHAARGTNVGRECCLEYFKGAIPISRLTRWYKTSGECPKDAIVFVTVQGKSICSDPKDKRVKKAVRYLQRTWKGGPQES

Target ORF information:

RefSeq Version	XM_005617215.2
Organism	Canis lupus familiaris(Dog)
Definition	Canis lupus familiaris chemokine (C-C motif) ligand 17 (CCL17), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005617215.2

ORF Insert Sequence:

ATGATTCCCT TGAAGATGCT GCTCCTGGTC ACGCTCCTCC TGGGGGCTTC TCTGCAGGTC 
ACCCATGCAG CTCGAGGCAC CAACGTGGGC CGGGAGTGCT GCCTAGAGTA CTTCAAAGGA 
GCCATTCCTA TCAGCAGGCT GACAAGGTGG TACAAGACTT CAGGGGAGTG TCCCAAGGAT 
GCCATCGTGT TTGTAACTGT CCAAGGCAAG TCCATCTGTT CCGACCCCAA GGACAAGAGG 
GTGAAGAAGG CGGTCAGATA TTTACAAAGA ACCTGGAAGG GAGGGCCCCA AGAGTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Effect of recombinant canine interferon-? on granulocyte-macrophage colony-stimulating factor, transforming growth factor-? and CC chemokine ligand 17 mRNA transcription in a canine keratinocyte cell line (CPEK).
Veterinary dermatology22(1)24-30(2011 Feb)
Shibata S,Maeda S,Kondo N,Inoue A,Maeda S,Chimura N,Fukata T

Identification of the signaling pathway of TNF-?-induced CCL17/TARC transcription in a canine keratinocyte cell line.
Veterinary immunology and immunopathology139(2-4)90-8(2011 Feb)
Shibata S,Maeda S,Kondo N,Chimura N,Inoue A,Fukata T

Augmentation of CCL17 and CCL28 gene expression by TNF-alpha, IL-1beta, or IFN-gamma in cultured canine keratinocytes.
Research in veterinary science88(3)422-6(2010 Jun)
Shibata S,Maeda S,Maeda S,Chimura N,Kondo N,Fukata T

Molecular cloning of canine thymus and activation-regulated chemokine (TARC) gene and its expression in various tissues.
The Journal of veterinary medical science63(9)1035-8(2001 Sep)
Maeda S,Mizuno T,Yamashita K,Kurata K,Masuda K,Ohno K,Tsujimoto H