IGF2R cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	IGF2R
Entrez Gene ID	281849
Full Name	insulin like growth factor 2 receptor
Synonyms	CI-MPR,CIMPR
General protein information	Preferred Names insulin like growth factor 2 receptor Names cation-independent mannose-6-phosphate receptor 300 kDa mannose 6-phosphate receptor CI Man-6-P receptor IGF-II receptor M6PR MPR 300 insulin-like growth factor II receptor insulin-like growth factor receptor type 2
Gene Type	protein-coding
Organism	Bos taurus(cattle)
Genome	Chromosome: 9 Map Location: 9q27-q28

mRNA and Protein(s)

mRNA	Protein	Name
NM_174352.2	NP_776777.1	cation-independent mannose-6-phosphate receptor precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	IGF2R	NP_776777.1
Xenopus tropicalis (tropical clawed frog)	igf2r	XP_002933917.2
Mus musculus (house mouse)	Igf2r	NP_034645.2
Danio rerio (zebrafish)	igf2r	NP_001034716.1
	IGF2R	XP_002804004.1
Canis lupus familiaris (dog)	IGF2R	NP_001116074.1
Pan troglodytes (chimpanzee)	IGF2R	XP_003311618.2
Homo sapiens (human)	IGF2R	NP_000867.2
Rattus norvegicus (Norway rat)	Igf2r	NP_036888.1
Gallus gallus (chicken)	IGF2R	NP_990301.1

Gene Ontology
Bibliography

Related articles in PubMed

Global misregulation of genes largely uncoupled to DNA methylome epimutations characterizes a congenital overgrowth syndrome.
Chen Z, Hagen DE, Ji T, Elsik CG, Rivera RM
Scientific reports7(1)12667(2017 Oct)

Melatonin significantly improves the developmental competence of bovine somatic cell nuclear transfer embryos.
Su J, Wang Y, Xing X, Zhang L, Sun H, Zhang Y
Journal of pineal research59(4)455-68(2015 Nov)

Possible role of IGF2 receptors in regulating selection of 2 dominant follicles in cattle selected for twin ovulations and births.
Aad PY, Echternkamp SE, Spicer LJ
Domestic animal endocrinology45(4)187-95(2013 Nov)

Tissue-specific and minor inter-individual variation in imprinting of IGF2R is a common feature of Bos taurus Concepti and not correlated with fetal weight.
Bebbere D, Bauersachs S, F?rst RW, Reichenbach HD, Reichenbach M, Medugorac I, Ulbrich SE, Wolf E, Ledda S, Hiendleder S
PloS one8(4)e59564(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

study hypothesizes that reduced granulosa cell insulin-like growth factor II receptor expression in F2 follicles of Twinner cows may play a role in the development of 2 or more dominant follicles
Title: Possible role of IGF2 receptors in regulating selection of 2 dominant follicles in cattle selected for twin ovulations and births.

imprinting of Bos taurus IGF2R is similar to mouse except in placenta, which could indicate an effect of reproductive strategy
Title: Tissue-specific and minor inter-individual variation in imprinting of IGF2R is a common feature of Bos taurus Concepti and not correlated with fetal weight.

Increases in CYP19A1 and FSHR mRNA expression and decreases in IGF2R mRNA expression in follicles of Twinners support the hypothesis that increased follicular development and steroidogenesis result from increased extra-ovarian IGF-1 production.
Title: Increased abundance of aromatase and follicle stimulating hormone receptor mRNA and decreased insulin-like growth factor-2 receptor mRNA in small ovarian follicles of cattle selected for twin births.

Sex-sorting procedure by flow cytometry did not affect the overall DNA methylation patterns of the IGF2 and IGF2R genes, although individual variation in their methylation patterns among bulls was observed.
Title: The methylation patterns of the IGF2 and IGF2R genes in bovine spermatozoa are not affected by flow-cytometric sex sorting.

Study demonstrates associations between IGF2R polymorphisms and growth- and body-related traits in cattle.
Title: Single nucleotide polymorphisms in the imprinted bovine insulin-like growth factor 2 receptor gene (IGF2R) are associated with body size traits in Irish Holstein-Friesian cattle.

The following IGF2R gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IGF2R cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa41522	NM_174352.2 Latest version!	Bos taurus insulin like growth factor 2 receptor (IGF2R), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$1371.30 $1959.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

IGF2R ( NM_174352.2 ) cDNA ORF clone, Bos taurus(cattle) -> NP_776777.1 Bos taurus insulin like growth factor 2 receptor (IGF2R), mRNA.

Price & Availability↑

CloneID	OBa41522
Clone ID Related Accession (Same CDS sequence)	NM_174352.2
Accession Version	NM_174352.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 7500bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-19
Organism	Bos taurus(cattle)
Product	cation-independent mannose-6-phosphate receptor precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF342811.1. On or before Mar 29, 2005 this sequence version replaced XM_600989.1, XM_612539.1, NM_174352.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF342811.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145415 [ECO:0000348] ##Evidence-Data-END##

ATGGAGGCGG CCGCCGGCCG GAGCTCGCAC CTGGGGCCCG CGCCCGCCGG GCGCCCGCCG 
CGGTGCCCGC TCCTGCTGCA GCTGCAGCTG CTGCTGCTGC TGCTGCTGCT GCCGCCGGGC 
TGGGTTCCCG GGGCCGCGGG CACCCAGGGC GCCGAGTTCC CAGAGCTGTG CAGTTATACA 
TGGGAAGCAG TGGATACCAA AAATAACATG CTTTATAAAA TCAACATCTG TGGAAATATG 
GGTGTTGCCC AGTGTGGACC ATCAAGTGCT GTCTGTATGC ATGACTTGAA GACAGACAGC 
TTTCATTCTG TGGGTGACTC TCTTTTGAAA ACAGCAAGCA GATCTCTTCT GGAATTTAAC 
ACAACAGTGA ACTGTAAGCA GCAGAATCAC AAAATTCAGA GTAGCATCAC CTTCTTATGT 
GGGAAAACCT TGGGAACTCC CGAGTTTGTA ACTGCAACAG ATTGTGTGCA TTACTTCGAG 
TGGAGGACTA CTGCAGCCTG CAAAAAGAAT ATATTTAAAG CGAATAAAGA GGTGCCCTGT 
TACGCTTTCG ACAGAGAGCT CAAGAAGCAC GATTTAAACC CACTGATCAA GACCAGCGGT 
GCTTACTTGG TGGACGACTC TGACCCGGAC ACATCTCTGT TCATCAATGT CTGCAGGGAC 
ATAGAGGTGC TCCGGGCCTC GAGTCCACAA GTGCGCGTGT GTCCCACCGG CGCGGCCGCC 
TGCCTGGTGC GAGGGGACCG CGCGTTCGAC GTGGGCCGGC CCCAGGAGGG GCTGAAGCTC 
GTGAGCAATG ACAGGCTCGT CCTGAGTTAC GTGAAGGAAG GGGCCGGCCA GCCCGACTTC 
TGTGACGGCC ACAGCCCGGC GGTGACCATC ACGTTCGTGT GCCCGTCGGA GCGCAGAGAG 
GGCACCATTC CCAAGCTCAC AGCGAAATCC AACTGCCGCT TTGAGATCGA GTGGGTCACC 
GAGTACGCCT GCCACAGGGA TTACCTGGAA AGCCGGAGCT GCTCCCTGAG CAGCGCGCAG 
CATGACGTGG CCGTCGACCT CCAGCCGTTG AGCCGGGTGG AAGCCTCAGA CTCCTTGTTC 
TACACCTCGG AGGCGGACGA GTATACATAT TATTTGAGCA TCTGCGGAGG AAGCCAAGCG 
CCCATCTGTA ATAAGAAAGA TGCTGCAGTG TGCCAAGTGA AAAAGGCAGA TTCCACTCAA 
GTCAAAGTGG CCGGGAGACC CCAGAACCTG ACCCTCCGGT ACTCGGATGG AGACCTCACC 
TTGATCTATT TCGGGGGTGA AGAGTGCAGC TCCGGCTTCC AGCGGATGAG TGTCATCAAC 
TTCGAGTGCA ATCAGACAGC AGGTAACAAT GGCAGAGGGG CTCCTGTGTT CACCGGGGAG 
GTGGACTGCA CCTACTTCTT CACGTGGGAT ACGAAGTACG CCTGTGTCCA CGAGAAGGAG 
GCCCTGCTGT GCGGCGTCTC CGACGGGAAA CAGCGCTTCG ACCTGTCGGC GCTGGCCCGG 
CACTCAGAAC TGGAACAAAA TTGGGAAGCT GTGGATGGCA GTCAGAGGGA AGCAGAAAAG 
AAGCATTTCT TCATTAACAT CTGCCACAGG GTCCTGCAGA CGGGCCAGGC ACGGGGCTGC 
CCCGAAGACG CGGCCGTGTG TGCCGTGGAT AAGAATGGAA GTAAAAATCT GGGCAGATTT 
ATTTCTTCTC CCACCAGAGA GAAAGGAAAT ATTCAGCTCT CTTACTCAGA TGGTGATGAG 
TGCGGTGGTG GCCAGAAGAT AATAACAAAT ATAACACTCA TGTGCAAACC AGGTGATTTA 
GAAAGTGCCC CGGTGCTGAC AACCTCCAGG GCTGACGGCT GCTTCTACGA GTTTGAGTGG 
CGCACGGCTG CAGCCTGCGT GCTCTCCAGG ACCGAGGGGG ACAACTGCAC TGTCTTTGAC 
TCCCAGGCAG GGTTTTCTTT CGACTTGACG CCTCTCACGA AGAAGGACGC CTACAAGGTC 
GAGACGGACA AGTACGAGTT CCACATCAAC GTGTGCGGCC CGGTGTCCGT GGGCGCCTGC 
CCGCCGGACT CGGGGGCCTG TCAGGTGTCC AGGAGTGATA GGAAGTCTTG GAACTTGGGA 
CGCAGCAATG CTAAGCTTTC GTATTACGAC GGGATGATCC AGCTGACCTA CAGGGACGGC 
ACACCCTACA ATAACGAGAA GCGCACGCCG AGAGCCACGC TCATCACCTT CCTCTGTGAC 
CGAGACGCCG GAGTGGGTTT CCCCGAATAT CAGGAGGAAG ATAACTCTAC ATACAACTTC 
CGGTGGTACA CCAGTTACGC CTGCCCGGAG GAGCCGCTGG AGTGCATCGT GACTGACCCC 
GTCACACTGG ACCAGTACGA CCTCTCCAGG CTAGCGAAAT CCGAGGGCGG TCCTGGGGGA 
AACTGGTACT CTCTGGACAA CGGCGGGGCA CGCAGCACGT GGCGGAAGTA CTACATCAAC 
GTGTGTCGTC CCCTGAACCC GGTGCCGGGC TGTGACCGCT ACGCGTCCGC CTGTCAGATG 
AAGTACCAGG GCGAGCAGGG CTCGTACTCT GAGACCGTCT CCATCAGCAA CCTGGGGGTG 
GCGAAGACGG GCCCCATGGT GGAGGACAGC GGCAGCCTGC TCCTGGAGTA CGTCAACGGC 
TCCGCCTGCA CCACCAGCGA CCAGAGGCGC ACCACCTACA CCACCAGGAT CCACCTTGTC 
TGCTCTACCG GCAGCCTGTA TACCCATCCC ATATTTTCTC TCAACTGGGA GTGTGTGGTC 
AGCTTCCTGT GGAACACGGC GGCAGCCTGT CCTATCCGAA TCACCACGGA CATAGACCAG 
GTCTGCTCCA TCAAGGACCC CAACAGCGGG TACGTGTTTG ATCTGAACCC ACTGAACAAT 
TCCCGAGGAT ACGTGGTTTT GGGCATCGGG AAGACGTTTC TGTTCAACGT GTGCGGTGAC 
ATGCCCGCCT GTGGCACCCT GGATGGGAAG CCAGCTTCCG GCTGCGAGGC AGAAGTCCAG 
ATGGACGACA TGAAGACCCT GAAGCCGGGC AGGCTGGTGG GCCTGGAGAA GAGCCTGCAG 
CTGTCCACCG AGGGCTTTAT AACCCTGAAC TACACGGGGC TTCCTTCCCA CCCCAACGGG 
AGGGCTGATG CCTTCATCAT CCGCTTCGTC TGCAATGATG ACGTTTACCC AGGGACACCC 
AAGTTCCTGC ACCAGGACAT CGACTCTAGC CTGGGGATCC GGGACACTTT CTTCGAGTTT 
GAAACCGCGC TGGCCTGTGT ACCTTCTCCG GTAGATTGCC AAGTCACAGA CCCCGCCGGG 
AACGAGTATG ATCTGAGTGG CCTGAGCAAG GCCAGGAAGC CGTGGACTGC GGTTGACACG 
TTCGATGAGG GGAAGAAGAG GACCTTCTAC CTGAGCGTGT GCACGCCTCT CCCGTACATT 
CCCGGCTGCC ACGGCACCGC TGTGGGGTGC TGCCTGGTGA CGGAAGACAG CAAGTTGAAC 
CTAGGCGTCG TGCAGATCAG TCCTCAGGTG GGCGCCAACG GGTCCCTGAG CCTCGTCTAC 
GTCAACGGGG ACAAGTGCAA GAACCAGCGT TTCTCCACCA GGATAAACCT CGAGTGTGCC 
CACACAACGG GCTCCCCGAC CTTTCAGCTC CAGAACGACT GTGAGTATGT GTTTCTCTGG 
AGAACCGTGG AAGCCTGTCC CGTCGTGCGT GCGGAAGGAG ACTACTGCGA GGTGAGAGAC 
CCAAGGCACG GCAACCTGTA TAACCTGATA CCTCTTGGTC TGAACGACAC TGTCGTGCGG 
GCCGGCGAAT ACACCTATTA CTTCCGCGTC TGCGGAGAGC TGACATCCGG CGTCTGCCCA 
ACCAGTGACA AGTCCAAGGT CATCTCATCA TGCCAGGAAA AGCGGGGACC CCAGGGATTT 
CAAAAAGTGG CAGGTCTGTT TAATCAGAAG CTGACCTACG AGAATGGGGT GCTGAAGATG 
AACTACACCG GGGGCGACAC CTGCCACAAG GTGTACCAGC GTTCCACCAC CATCTTTTTC 
TACTGCGACC GCAGCACGCA GGCGCCCGTG TTTCTCCAGG AGACGTCCGA TTGCTCCTAC 
CTGTTTGAGT GGCGCACGCA GTACGCCTGC CCGCCCTACG ACCTGACCGA GTGTTCGTTC 
AAAAACGAGG CTGGGGAAAC CTACGACCTC TCGTCTCTGT CGAGGTACAG CGACAACTGG 
GAGGCTGTCA CGGGCACAGG GTCCACCGAG CACTACCTCA TCAACGTGTG CAAGTCCCTG 
TCCCCGCAGG CTGGCTCAGA TCCGTGCCCT CCGGAGGCGG CCGTGTGTCT GCTGGGCGGC 
CCCAAGCCCG TGAACCTGGG CAGGGTGCGG GACAGTCCTC AGTGGAGCCA GGGCTTGACC 
CTCCTGAAGT ACGTTGACGG TGACTTGTGT CCAGACCAGA TTCGGAAGAA GTCAACCACC 
ATCCGCTTCA CGTGCAGCGA GAGCCACGTG AACTCCAGGC CCATGTTCAT CAGCGCTGTG 
GAGGACTGCG AATACACCTT CTCCTGGCCC ACGGCCGCCG CCTGCGCGGT CAAGAGCAAC 
GTGCACGACG ACTGCCAGGT CACCAACCCC GCCACGGGAC ACCTGTTTGA CCTGAGCTCT 
CTGAGCGGCC GGGCCGGCTT CACCGCCGCC TACAGCGAGA AGGGGTTAGT CTACCTCAGC 
GTGTGCGGGG ACAACGAGAA CTGCGCCAAC GGCGTGGGGG CCTGCTTTGG GCAGACCAGG 
ATCAGCGTGG GCAAGGCGAG CAAGAGGCTG ACCTACGTGG ACCAGGTCTT GCAACTGGTG 
TATGAGGGCG GCTCCCCCTG CCCCTCCAAG ACCGGCCTGA GCTACAAGAG CGTCATCAGC 
TTCGTGTGCA GGCCTGAGGT CGGGCCCACC AACAGGCCCA TGCTGATCTC CCTGGACAAG 
CGCACGTGCA CGCTTTTCTT CTCCTGGCAC ACACCCCTGG CCTGCGAGCA GACGACCGAG 
TGCTCCGTGA GGAACGGCAG CTCCCTCATC GACCTGTCCC CACTCATCCA CCGCACCGGG 
GGTTACGAAG CATACGATGA GAGTGAGGAC GACGGCTCCG ACACCAGCCC TGACTTCTAC 
ATCAACATCT GCCAGCCGCT CAACCCCATG CACGGGTTGG CCTGCCCCGC CGGCACGGCC 
GTGTGCAAGG TTCCCGTGGA CGGCCCCCCG ATAGATATTG GCCGAGTGGC AGGACCTCCG 
ATCCTCAATC CCATAGCCAA CGAAGTTTAC TTGAACTTTG AAAGCAGCAC TCCTTGCTTG 
GCGGACCGGC ACTTCAACTA CACCTCACTG ATCACGTTCC ACTGTAAGCG GGGCGTGAGC 
ATGGGAACGC CAAAACTGCT GAGGACCAGT GTGTGTGACT TCGTGTTTGA GTGGGAGACT 
CCTCTGGTCT GTCCCGACGA AGTGAAGACG GACGGCTGCT CCCTCACGGA CGAACAGCTG 
TACTACAGCT TCAACCTGTC CAGCCTCTCC AAGAGCACCT TCAAGGTGAC CCGAGGCCCG 
CACACCTACA GTGTGGGGGT GTGCACCGCA GCCGCAGGCC TGGACGAAGG AGGCTGCAAG 
GACGGTGCTG TCTGCCTGCT GTCCGGGAGC AAGGGGGCGT CTTTCGGGCG GCTGGCGTCC 
ATGAAGCTGG ACTACAGGCA TCAGGACGAA GCTGTCATCC TGAGTTACGC CAACGGAGAC 
ACTTGCCCTC CGGAAACTGA GGACGGCGAG CCGTGTGTGT TCCCCTTCGT GTTCAACGGG 
AAGAGCTACG AGGAGTGTGT TGTGGAGAGC AGGGCCAGGC TCTGGTGCGC GACCACCGCC 
AACTACGACA GAGACCACGA GTGGGGCTTC TGCAAGCACT CCACCAGCCA CCGGACGTCC 
GTCATCATCT TCAAGTGTGA CGAGGACGCC GACGTGGGGC GGCCCCAGGT CTTCAGCGAG 
GTGCGCGGCT GTGAGGTGAC CTTCGAGTGG AAGACGAAGG TGGTCTGCCC CCCGAAGAAG 
ATGGAGTGCA AGTTCGTCCA GAAGCACCGG ACCTACGACC TGCGGCTGCT CTCGTCCCTC 
ACCGGCTCCT GGTCCTTCGT CCACAACGGA GCCTCGTACT ACATCAACCT GTGTCAGAAA 
ATATACAAGG GACCCCAGGA CTGCTCGGAG AGAGCCAGCG TGTGCAAAAA GAGCACCTCT 
GGCGAGGTGC AGGTCCTCGG GCTCGTTCAC ACACAGAAGC TGGATGTTGT AGATGACAGA 
GTCATCGTAA CTTACTCTAA AGGCCACTAC TGTGGGGACA ATAAGACAGC GTCTGCTGTC 
ATCGAGCTGA CCTGTGCCAA GACAGTGGGG CGGCCTTCGT TCACGAGGTT CGACGTCGAC 
AGCTGCACCT ACCACTTCAG CTGGGACTCA CGAGCGGCCT GCGCCGTGAA GCCTCAGGAG 
GTGCAGATGG TGAATGGGAC CATCACCAAC CCGGCCAACG GCCGGAGCTT CAGCCTCGGG 
GATATTTACT TCAAACGATT CAGCGCCTCT GGGGACGTGA GAACCAACGG GGACAGGTAC 
ATCTACGAGA TCCAGCTGTC GTCCATCACG GGCTCCAGCA GCCCCGCCTG CTCTGGGGCC 
AGCATCTGCC AGAGGAAGGC CAACGACCAG CACTTCAGTC GCAAAGTCGG AACCTCCAAC 
CAAACCAGAT ACTACGTTCA AGATGGCGAC CTGGATGTGG TGTTCACCTC GTCCTCCAAG 
TGTGGAAAAG ACAAGACAAA GTCTGTGTCC TCCACCATCT TCTTCCACTG TGACCCCCTG 
GTGAAGGACG GGATCCCCGA GTTCAGCCAC GAGACTGCCG ACTGCCAGTA CCTCTTCTCC 
TGGCACACCT CTGCCGTGTG CCCGCTGGGG GCGGGCTTCG ACGAGGAGAT CGCAGGGGAT 
GACGCCCAGG AGCACAAAGG GCTCTCAGAG CGCAGCCAGG CGGTCGGGGC AGTGCTCAGC 
CTGCTGCTGG TGGCACTCAC CGCCTGCCTG CTCACCCTGC TGCTGTACAA GAAGGAGCGC 
CGGGAGATGG TAATGAGCAG GCTTACCAAC TGCTGCCGCC GGAGCGCGAA CGTGTCCTAC 
AAGTACTCGA AGGTGAACAA GGAGGAGGAG GCCGACGAGA ACGAGACCGA GTGGCTGATG 
GAGGAGATCC AGCCGCCGGC GCCGCGGCCC GGGAAGGAGG GCCAGGAGAA CGGGCACGTG 
GCCGCCAAGT CGGTGAGAGC TGCCGACACG CTGAGCGCCC TGCACGGCGA CGAGCAGGAT 
AGCGAGGACG AGGTCCTGAC GCTGCCCGAG GTGAAGGTGC GCCCGCCAGG CCGGGCTCCT 
GGTGCCGAAG GTGGCCCCCC GCTGCGGCCA CTGCCTCGGA AGGCGCCACC GCCGCTGCGG 
GCGGACGACC GGGTGGGGCT GGTGCGTGGG GAGCCGGCGC GCCGGGGGCG GCCCCGGGCG 
GCGGCCACGC CCATCAGCAC CTTCCACGAC GACAGCGACG AGGACCTCCT GCACGTCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_776777.1
CDS	153..7652
Translation	MEAAAGRSSHLGPAPAGRPPRCPLLLQLQLLLLLLLLPPGWVPGAAGTQGAEFPELCSYTWEAVDTKNNMLYKINICGNMGVAQCGPSSAVCMHDLKTDSFHSVGDSLLKTASRSLLEFNTTVNCKQQNHKIQSSITFLCGKTLGTPEFVTATDCVHYFEWRTTAACKKNIFKANKEVPCYAFDRELKKHDLNPLIKTSGAYLVDDSDPDTSLFINVCRDIEVLRASSPQVRVCPTGAAACLVRGDRAFDVGRPQEGLKLVSNDRLVLSYVKEGAGQPDFCDGHSPAVTITFVCPSERREGTIPKLTAKSNCRFEIEWVTEYACHRDYLESRSCSLSSAQHDVAVDLQPLSRVEASDSLFYTSEADEYTYYLSICGGSQAPICNKKDAAVCQVKKADSTQVKVAGRPQNLTLRYSDGDLTLIYFGGEECSSGFQRMSVINFECNQTAGNNGRGAPVFTGEVDCTYFFTWDTKYACVHEKEALLCGVSDGKQRFDLSALARHSELEQNWEAVDGSQREAEKKHFFINICHRVLQTGQARGCPEDAAVCAVDKNGSKNLGRFISSPTREKGNIQLSYSDGDECGGGQKIITNITLMCKPGDLESAPVLTTSRADGCFYEFEWRTAAACVLSRTEGDNCTVFDSQAGFSFDLTPLTKKDAYKVETDKYEFHINVCGPVSVGACPPDSGACQVSRSDRKSWNLGRSNAKLSYYDGMIQLTYRDGTPYNNEKRTPRATLITFLCDRDAGVGFPEYQEEDNSTYNFRWYTSYACPEEPLECIVTDPVTLDQYDLSRLAKSEGGPGGNWYSLDNGGARSTWRKYYINVCRPLNPVPGCDRYASACQMKYQGEQGSYSETVSISNLGVAKTGPMVEDSGSLLLEYVNGSACTTSDQRRTTYTTRIHLVCSTGSLYTHPIFSLNWECVVSFLWNTAAACPIRITTDIDQVCSIKDPNSGYVFDLNPLNNSRGYVVLGIGKTFLFNVCGDMPACGTLDGKPASGCEAEVQMDDMKTLKPGRLVGLEKSLQLSTEGFITLNYTGLPSHPNGRADAFIIRFVCNDDVYPGTPKFLHQDIDSSLGIRDTFFEFETALACVPSPVDCQVTDPAGNEYDLSGLSKARKPWTAVDTFDEGKKRTFYLSVCTPLPYIPGCHGTAVGCCLVTEDSKLNLGVVQISPQVGANGSLSLVYVNGDKCKNQRFSTRINLECAHTTGSPTFQLQNDCEYVFLWRTVEACPVVRAEGDYCEVRDPRHGNLYNLIPLGLNDTVVRAGEYTYYFRVCGELTSGVCPTSDKSKVISSCQEKRGPQGFQKVAGLFNQKLTYENGVLKMNYTGGDTCHKVYQRSTTIFFYCDRSTQAPVFLQETSDCSYLFEWRTQYACPPYDLTECSFKNEAGETYDLSSLSRYSDNWEAVTGTGSTEHYLINVCKSLSPQAGSDPCPPEAAVCLLGGPKPVNLGRVRDSPQWSQGLTLLKYVDGDLCPDQIRKKSTTIRFTCSESHVNSRPMFISAVEDCEYTFSWPTAAACAVKSNVHDDCQVTNPATGHLFDLSSLSGRAGFTAAYSEKGLVYLSVCGDNENCANGVGACFGQTRISVGKASKRLTYVDQVLQLVYEGGSPCPSKTGLSYKSVISFVCRPEVGPTNRPMLISLDKRTCTLFFSWHTPLACEQTTECSVRNGSSLIDLSPLIHRTGGYEAYDESEDDGSDTSPDFYINICQPLNPMHGLACPAGTAVCKVPVDGPPIDIGRVAGPPILNPIANEVYLNFESSTPCLADRHFNYTSLITFHCKRGVSMGTPKLLRTSVCDFVFEWETPLVCPDEVKTDGCSLTDEQLYYSFNLSSLSKSTFKVTRGPHTYSVGVCTAAAGLDEGGCKDGAVCLLSGSKGASFGRLASMKLDYRHQDEAVILSYANGDTCPPETEDGEPCVFPFVFNGKSYEECVVESRARLWCATTANYDRDHEWGFCKHSTSHRTSVIIFKCDEDADVGRPQVFSEVRGCEVTFEWKTKVVCPPKKMECKFVQKHRTYDLRLLSSLTGSWSFVHNGASYYINLCQKIYKGPQDCSERASVCKKSTSGEVQVLGLVHTQKLDVVDDRVIVTYSKGHYCGDNKTASAVIELTCAKTVGRPSFTRFDVDSCTYHFSWDSRAACAVKPQEVQMVNGTITNPANGRSFSLGDIYFKRFSASGDVRTNGDRYIYEIQLSSITGSSSPACSGASICQRKANDQHFSRKVGTSNQTRYYVQDGDLDVVFTSSSKCGKDKTKSVSSTIFFHCDPLVKDGIPEFSHETADCQYLFSWHTSAVCPLGAGFDEEIAGDDAQEHKGLSERSQAVGAVLSLLLVALTACLLTLLLYKKERREMVMSRLTNCCRRSANVSYKYSKVNKEEEADENETEWLMEEIQPPAPRPGKEGQENGHVAAKSVRAADTLSALHGDEQDSEDEVLTLPEVKVRPPGRAPGAEGGPPLRPLPRKAPPPLRADDRVGLVRGEPARRGRPRAAATPISTFHDDSDEDLLHV

Target ORF information:

RefSeq Version	NM_174352.2
Organism	Bos taurus(cattle)
Definition	Bos taurus insulin like growth factor 2 receptor (IGF2R), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174352.2

ORF Insert Sequence:

ATGGAGGCGG CCGCCGGCCG GAGCTCGCAC CTGGGGCCCG CGCCCGCCGG GCGCCCGCCG 
CGGTGCCCGC TCCTGCTGCA GCTGCAGCTG CTGCTGCTGC TGCTGCTGCT GCCGCCGGGC 
TGGGTTCCCG GGGCCGCGGG CACCCAGGGC GCCGAGTTCC CAGAGCTGTG CAGTTATACA 
TGGGAAGCAG TGGATACCAA AAATAACATG CTTTATAAAA TCAACATCTG TGGAAATATG 
GGTGTTGCCC AGTGTGGACC ATCAAGTGCT GTCTGTATGC ATGACTTGAA GACAGACAGC 
TTTCATTCTG TGGGTGACTC TCTTTTGAAA ACAGCAAGCA GATCTCTTCT GGAATTTAAC 
ACAACAGTGA ACTGTAAGCA GCAGAATCAC AAAATTCAGA GTAGCATCAC CTTCTTATGT 
GGGAAAACCT TGGGAACTCC CGAGTTTGTA ACTGCAACAG ATTGTGTGCA TTACTTCGAG 
TGGAGGACTA CTGCAGCCTG CAAAAAGAAT ATATTTAAAG CGAATAAAGA GGTGCCCTGT 
TACGCTTTCG ACAGAGAGCT CAAGAAGCAC GATTTAAACC CACTGATCAA GACCAGCGGT 
GCTTACTTGG TGGACGACTC TGACCCGGAC ACATCTCTGT TCATCAATGT CTGCAGGGAC 
ATAGAGGTGC TCCGGGCCTC GAGTCCACAA GTGCGCGTGT GTCCCACCGG CGCGGCCGCC 
TGCCTGGTGC GAGGGGACCG CGCGTTCGAC GTGGGCCGGC CCCAGGAGGG GCTGAAGCTC 
GTGAGCAATG ACAGGCTCGT CCTGAGTTAC GTGAAGGAAG GGGCCGGCCA GCCCGACTTC 
TGTGACGGCC ACAGCCCGGC GGTGACCATC ACGTTCGTGT GCCCGTCGGA GCGCAGAGAG 
GGCACCATTC CCAAGCTCAC AGCGAAATCC AACTGCCGCT TTGAGATCGA GTGGGTCACC 
GAGTACGCCT GCCACAGGGA TTACCTGGAA AGCCGGAGCT GCTCCCTGAG CAGCGCGCAG 
CATGACGTGG CCGTCGACCT CCAGCCGTTG AGCCGGGTGG AAGCCTCAGA CTCCTTGTTC 
TACACCTCGG AGGCGGACGA GTATACATAT TATTTGAGCA TCTGCGGAGG AAGCCAAGCG 
CCCATCTGTA ATAAGAAAGA TGCTGCAGTG TGCCAAGTGA AAAAGGCAGA TTCCACTCAA 
GTCAAAGTGG CCGGGAGACC CCAGAACCTG ACCCTCCGGT ACTCGGATGG AGACCTCACC 
TTGATCTATT TCGGGGGTGA AGAGTGCAGC TCCGGCTTCC AGCGGATGAG TGTCATCAAC 
TTCGAGTGCA ATCAGACAGC AGGTAACAAT GGCAGAGGGG CTCCTGTGTT CACCGGGGAG 
GTGGACTGCA CCTACTTCTT CACGTGGGAT ACGAAGTACG CCTGTGTCCA CGAGAAGGAG 
GCCCTGCTGT GCGGCGTCTC CGACGGGAAA CAGCGCTTCG ACCTGTCGGC GCTGGCCCGG 
CACTCAGAAC TGGAACAAAA TTGGGAAGCT GTGGATGGCA GTCAGAGGGA AGCAGAAAAG 
AAGCATTTCT TCATTAACAT CTGCCACAGG GTCCTGCAGA CGGGCCAGGC ACGGGGCTGC 
CCCGAAGACG CGGCCGTGTG TGCCGTGGAT AAGAATGGAA GTAAAAATCT GGGCAGATTT 
ATTTCTTCTC CCACCAGAGA GAAAGGAAAT ATTCAGCTCT CTTACTCAGA TGGTGATGAG 
TGCGGTGGTG GCCAGAAGAT AATAACAAAT ATAACACTCA TGTGCAAACC AGGTGATTTA 
GAAAGTGCCC CGGTGCTGAC AACCTCCAGG GCTGACGGCT GCTTCTACGA GTTTGAGTGG 
CGCACGGCTG CAGCCTGCGT GCTCTCCAGG ACCGAGGGGG ACAACTGCAC TGTCTTTGAC 
TCCCAGGCAG GGTTTTCTTT CGACTTGACG CCTCTCACGA AGAAGGACGC CTACAAGGTC 
GAGACGGACA AGTACGAGTT CCACATCAAC GTGTGCGGCC CGGTGTCCGT GGGCGCCTGC 
CCGCCGGACT CGGGGGCCTG TCAGGTGTCC AGGAGTGATA GGAAGTCTTG GAACTTGGGA 
CGCAGCAATG CTAAGCTTTC GTATTACGAC GGGATGATCC AGCTGACCTA CAGGGACGGC 
ACACCCTACA ATAACGAGAA GCGCACGCCG AGAGCCACGC TCATCACCTT CCTCTGTGAC 
CGAGACGCCG GAGTGGGTTT CCCCGAATAT CAGGAGGAAG ATAACTCTAC ATACAACTTC 
CGGTGGTACA CCAGTTACGC CTGCCCGGAG GAGCCGCTGG AGTGCATCGT GACTGACCCC 
GTCACACTGG ACCAGTACGA CCTCTCCAGG CTAGCGAAAT CCGAGGGCGG TCCTGGGGGA 
AACTGGTACT CTCTGGACAA CGGCGGGGCA CGCAGCACGT GGCGGAAGTA CTACATCAAC 
GTGTGTCGTC CCCTGAACCC GGTGCCGGGC TGTGACCGCT ACGCGTCCGC CTGTCAGATG 
AAGTACCAGG GCGAGCAGGG CTCGTACTCT GAGACCGTCT CCATCAGCAA CCTGGGGGTG 
GCGAAGACGG GCCCCATGGT GGAGGACAGC GGCAGCCTGC TCCTGGAGTA CGTCAACGGC 
TCCGCCTGCA CCACCAGCGA CCAGAGGCGC ACCACCTACA CCACCAGGAT CCACCTTGTC 
TGCTCTACCG GCAGCCTGTA TACCCATCCC ATATTTTCTC TCAACTGGGA GTGTGTGGTC 
AGCTTCCTGT GGAACACGGC GGCAGCCTGT CCTATCCGAA TCACCACGGA CATAGACCAG 
GTCTGCTCCA TCAAGGACCC CAACAGCGGG TACGTGTTTG ATCTGAACCC ACTGAACAAT 
TCCCGAGGAT ACGTGGTTTT GGGCATCGGG AAGACGTTTC TGTTCAACGT GTGCGGTGAC 
ATGCCCGCCT GTGGCACCCT GGATGGGAAG CCAGCTTCCG GCTGCGAGGC AGAAGTCCAG 
ATGGACGACA TGAAGACCCT GAAGCCGGGC AGGCTGGTGG GCCTGGAGAA GAGCCTGCAG 
CTGTCCACCG AGGGCTTTAT AACCCTGAAC TACACGGGGC TTCCTTCCCA CCCCAACGGG 
AGGGCTGATG CCTTCATCAT CCGCTTCGTC TGCAATGATG ACGTTTACCC AGGGACACCC 
AAGTTCCTGC ACCAGGACAT CGACTCTAGC CTGGGGATCC GGGACACTTT CTTCGAGTTT 
GAAACCGCGC TGGCCTGTGT ACCTTCTCCG GTAGATTGCC AAGTCACAGA CCCCGCCGGG 
AACGAGTATG ATCTGAGTGG CCTGAGCAAG GCCAGGAAGC CGTGGACTGC GGTTGACACG 
TTCGATGAGG GGAAGAAGAG GACCTTCTAC CTGAGCGTGT GCACGCCTCT CCCGTACATT 
CCCGGCTGCC ACGGCACCGC TGTGGGGTGC TGCCTGGTGA CGGAAGACAG CAAGTTGAAC 
CTAGGCGTCG TGCAGATCAG TCCTCAGGTG GGCGCCAACG GGTCCCTGAG CCTCGTCTAC 
GTCAACGGGG ACAAGTGCAA GAACCAGCGT TTCTCCACCA GGATAAACCT CGAGTGTGCC 
CACACAACGG GCTCCCCGAC CTTTCAGCTC CAGAACGACT GTGAGTATGT GTTTCTCTGG 
AGAACCGTGG AAGCCTGTCC CGTCGTGCGT GCGGAAGGAG ACTACTGCGA GGTGAGAGAC 
CCAAGGCACG GCAACCTGTA TAACCTGATA CCTCTTGGTC TGAACGACAC TGTCGTGCGG 
GCCGGCGAAT ACACCTATTA CTTCCGCGTC TGCGGAGAGC TGACATCCGG CGTCTGCCCA 
ACCAGTGACA AGTCCAAGGT CATCTCATCA TGCCAGGAAA AGCGGGGACC CCAGGGATTT 
CAAAAAGTGG CAGGTCTGTT TAATCAGAAG CTGACCTACG AGAATGGGGT GCTGAAGATG 
AACTACACCG GGGGCGACAC CTGCCACAAG GTGTACCAGC GTTCCACCAC CATCTTTTTC 
TACTGCGACC GCAGCACGCA GGCGCCCGTG TTTCTCCAGG AGACGTCCGA TTGCTCCTAC 
CTGTTTGAGT GGCGCACGCA GTACGCCTGC CCGCCCTACG ACCTGACCGA GTGTTCGTTC 
AAAAACGAGG CTGGGGAAAC CTACGACCTC TCGTCTCTGT CGAGGTACAG CGACAACTGG 
GAGGCTGTCA CGGGCACAGG GTCCACCGAG CACTACCTCA TCAACGTGTG CAAGTCCCTG 
TCCCCGCAGG CTGGCTCAGA TCCGTGCCCT CCGGAGGCGG CCGTGTGTCT GCTGGGCGGC 
CCCAAGCCCG TGAACCTGGG CAGGGTGCGG GACAGTCCTC AGTGGAGCCA GGGCTTGACC 
CTCCTGAAGT ACGTTGACGG TGACTTGTGT CCAGACCAGA TTCGGAAGAA GTCAACCACC 
ATCCGCTTCA CGTGCAGCGA GAGCCACGTG AACTCCAGGC CCATGTTCAT CAGCGCTGTG 
GAGGACTGCG AATACACCTT CTCCTGGCCC ACGGCCGCCG CCTGCGCGGT CAAGAGCAAC 
GTGCACGACG ACTGCCAGGT CACCAACCCC GCCACGGGAC ACCTGTTTGA CCTGAGCTCT 
CTGAGCGGCC GGGCCGGCTT CACCGCCGCC TACAGCGAGA AGGGGTTAGT CTACCTCAGC 
GTGTGCGGGG ACAACGAGAA CTGCGCCAAC GGCGTGGGGG CCTGCTTTGG GCAGACCAGG 
ATCAGCGTGG GCAAGGCGAG CAAGAGGCTG ACCTACGTGG ACCAGGTCTT GCAACTGGTG 
TATGAGGGCG GCTCCCCCTG CCCCTCCAAG ACCGGCCTGA GCTACAAGAG CGTCATCAGC 
TTCGTGTGCA GGCCTGAGGT CGGGCCCACC AACAGGCCCA TGCTGATCTC CCTGGACAAG 
CGCACGTGCA CGCTTTTCTT CTCCTGGCAC ACACCCCTGG CCTGCGAGCA GACGACCGAG 
TGCTCCGTGA GGAACGGCAG CTCCCTCATC GACCTGTCCC CACTCATCCA CCGCACCGGG 
GGTTACGAAG CATACGATGA GAGTGAGGAC GACGGCTCCG ACACCAGCCC TGACTTCTAC 
ATCAACATCT GCCAGCCGCT CAACCCCATG CACGGGTTGG CCTGCCCCGC CGGCACGGCC 
GTGTGCAAGG TTCCCGTGGA CGGCCCCCCG ATAGATATTG GCCGAGTGGC AGGACCTCCG 
ATCCTCAATC CCATAGCCAA CGAAGTTTAC TTGAACTTTG AAAGCAGCAC TCCTTGCTTG 
GCGGACCGGC ACTTCAACTA CACCTCACTG ATCACGTTCC ACTGTAAGCG GGGCGTGAGC 
ATGGGAACGC CAAAACTGCT GAGGACCAGT GTGTGTGACT TCGTGTTTGA GTGGGAGACT 
CCTCTGGTCT GTCCCGACGA AGTGAAGACG GACGGCTGCT CCCTCACGGA CGAACAGCTG 
TACTACAGCT TCAACCTGTC CAGCCTCTCC AAGAGCACCT TCAAGGTGAC CCGAGGCCCG 
CACACCTACA GTGTGGGGGT GTGCACCGCA GCCGCAGGCC TGGACGAAGG AGGCTGCAAG 
GACGGTGCTG TCTGCCTGCT GTCCGGGAGC AAGGGGGCGT CTTTCGGGCG GCTGGCGTCC 
ATGAAGCTGG ACTACAGGCA TCAGGACGAA GCTGTCATCC TGAGTTACGC CAACGGAGAC 
ACTTGCCCTC CGGAAACTGA GGACGGCGAG CCGTGTGTGT TCCCCTTCGT GTTCAACGGG 
AAGAGCTACG AGGAGTGTGT TGTGGAGAGC AGGGCCAGGC TCTGGTGCGC GACCACCGCC 
AACTACGACA GAGACCACGA GTGGGGCTTC TGCAAGCACT CCACCAGCCA CCGGACGTCC 
GTCATCATCT TCAAGTGTGA CGAGGACGCC GACGTGGGGC GGCCCCAGGT CTTCAGCGAG 
GTGCGCGGCT GTGAGGTGAC CTTCGAGTGG AAGACGAAGG TGGTCTGCCC CCCGAAGAAG 
ATGGAGTGCA AGTTCGTCCA GAAGCACCGG ACCTACGACC TGCGGCTGCT CTCGTCCCTC 
ACCGGCTCCT GGTCCTTCGT CCACAACGGA GCCTCGTACT ACATCAACCT GTGTCAGAAA 
ATATACAAGG GACCCCAGGA CTGCTCGGAG AGAGCCAGCG TGTGCAAAAA GAGCACCTCT 
GGCGAGGTGC AGGTCCTCGG GCTCGTTCAC ACACAGAAGC TGGATGTTGT AGATGACAGA 
GTCATCGTAA CTTACTCTAA AGGCCACTAC TGTGGGGACA ATAAGACAGC GTCTGCTGTC 
ATCGAGCTGA CCTGTGCCAA GACAGTGGGG CGGCCTTCGT TCACGAGGTT CGACGTCGAC 
AGCTGCACCT ACCACTTCAG CTGGGACTCA CGAGCGGCCT GCGCCGTGAA GCCTCAGGAG 
GTGCAGATGG TGAATGGGAC CATCACCAAC CCGGCCAACG GCCGGAGCTT CAGCCTCGGG 
GATATTTACT TCAAACGATT CAGCGCCTCT GGGGACGTGA GAACCAACGG GGACAGGTAC 
ATCTACGAGA TCCAGCTGTC GTCCATCACG GGCTCCAGCA GCCCCGCCTG CTCTGGGGCC 
AGCATCTGCC AGAGGAAGGC CAACGACCAG CACTTCAGTC GCAAAGTCGG AACCTCCAAC 
CAAACCAGAT ACTACGTTCA AGATGGCGAC CTGGATGTGG TGTTCACCTC GTCCTCCAAG 
TGTGGAAAAG ACAAGACAAA GTCTGTGTCC TCCACCATCT TCTTCCACTG TGACCCCCTG 
GTGAAGGACG GGATCCCCGA GTTCAGCCAC GAGACTGCCG ACTGCCAGTA CCTCTTCTCC 
TGGCACACCT CTGCCGTGTG CCCGCTGGGG GCGGGCTTCG ACGAGGAGAT CGCAGGGGAT 
GACGCCCAGG AGCACAAAGG GCTCTCAGAG CGCAGCCAGG CGGTCGGGGC AGTGCTCAGC 
CTGCTGCTGG TGGCACTCAC CGCCTGCCTG CTCACCCTGC TGCTGTACAA GAAGGAGCGC 
CGGGAGATGG TAATGAGCAG GCTTACCAAC TGCTGCCGCC GGAGCGCGAA CGTGTCCTAC 
AAGTACTCGA AGGTGAACAA GGAGGAGGAG GCCGACGAGA ACGAGACCGA GTGGCTGATG 
GAGGAGATCC AGCCGCCGGC GCCGCGGCCC GGGAAGGAGG GCCAGGAGAA CGGGCACGTG 
GCCGCCAAGT CGGTGAGAGC TGCCGACACG CTGAGCGCCC TGCACGGCGA CGAGCAGGAT 
AGCGAGGACG AGGTCCTGAC GCTGCCCGAG GTGAAGGTGC GCCCGCCAGG CCGGGCTCCT 
GGTGCCGAAG GTGGCCCCCC GCTGCGGCCA CTGCCTCGGA AGGCGCCACC GCCGCTGCGG 
GCGGACGACC GGGTGGGGCT GGTGCGTGGG GAGCCGGCGC GCCGGGGGCG GCCCCGGGCG 
GCGGCCACGC CCATCAGCAC CTTCCACGAC GACAGCGACG AGGACCTCCT GCACGTCTAG