CDCP1, His, Rhesus macaque
CDCP1, His, Rhesus Macaque

Immobilized CDCP1, His, Rhesus macaque, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-CDCP1 Antibody, hFc Tag with the EC50 of 8.6ng/ml determined by ELISA.

CDCP1, His, Rhesus Macaque

The purity of CDCP1, His, Rhesus macaque is greater than 95% as determined by SEC-HPLC.

CDCP1, His, Rhesus Macaque

CDCP1, His, Rhesus macaque on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

CDCP1, His, Rhesus macaque

Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression.
Z06434
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Product Introduction
Species Rhesus macaque
Protein Construction
CDCP1 (Ala29-Thr667)_x000D_
Accession # XP_001114659.2		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 73.2 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 80-115 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • CDCP1, His, Rhesus Macaque
    • CDCP1, His, Rhesus Macaque

    Immobilized CDCP1, His, Rhesus macaque, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-CDCP1 Antibody, hFc Tag with the EC50 of 8.6ng/ml determined by ELISA.

  • CDCP1, His, Rhesus Macaque
    • CDCP1, His, Rhesus Macaque

    The purity of CDCP1, His, Rhesus macaque is greater than 95% as determined by SEC-HPLC.

  • CDCP1, His, Rhesus Macaque
    • CDCP1, His, Rhesus Macaque

    CDCP1, His, Rhesus macaque on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss of CDCP1 have been observed in the same cancer types to promote metastatic progression.
Synonyms CDCP1; CD318; SIMA135; TRASK; UNQ2486; PRO5773

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.