Loaded Human IL-13, hFc Tag on ProA-Biosensor can bind IL-13Ra2, His, Mouse, His Tag with an affinity constant of 1.88 nM as determined in BLI assay (Gator® Prime).
Immobilized IL-13Ra2, His, Mouse, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Human IL-13, hFc Tag with the EC50 of 10.2ng/ml determined by ELISA.
The purity of IL-13Ra2, His, Mouse is greater than 95% as determined by SEC-HPLC.
IL-13Ra2, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
IL-13Ra2, His, Mouse
Two type 1 membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with differing affinities. The lower affinity IL-13 binding protein, previously designated IL-13 R alpha, IL-13 R alpha ' or NR4, is now referred to as IL-13 R alpha 1. The high-affinity IL-13 binding protein, previously also designated IL-13 R or IL-13 R alpha ', is now referred to as IL-13 R alpha 2.
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