IL-12, His, Mouse
IL-12, His, Mouse

Measured by its ability to induce Interferon gamma secretion by human natural killer lymphoma NK-92 cells. The ED50 for this effect is 0.5 - 2 ng/mL.

IL-12, His, Mouse

The purity of IL-12, His, Mouse is greater than 95% as determined by SEC-HPLC.

IL-12, His, Mouse

IL-12, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

IL-12, His, Mouse

Interleukin 12 (IL-12) is a pleiotropic cytokine that plays an essential role in Th1-type immune response against cancer, a condition where cells in a particular part of the body grow and reproduce uncontrollably.
Z06183
¥104,464.00

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Product Introduction
Species Mouse
Protein Construction
IL-12 [Arg23-Ala215(IL-12A)&Met23-Ser335(IL-12B)]
Accession # P43431(IL-12A)&P43432(IL-12B)		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its ability to induce Interferon gamma secretion by human natural killer lymphoma NK­92 cells. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 22.80 kDa(IL-12A)&35.79 kDa(IL-12B)
Apparent Molecular Weight Due to glycosylation, the protein migrates to 25-30 kDa(IL-12A)&45-55 kDa(IL-12B) based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • IL-12, His, Mouse
    • IL-12, His, Mouse

    Measured by its ability to induce Interferon gamma secretion by human natural killer lymphoma NK-92 cells. The ED50 for this effect is 0.5 - 2 ng/mL.

  • IL-12, His, Mouse
    • IL-12, His, Mouse

    The purity of IL-12, His, Mouse is greater than 95% as determined by SEC-HPLC.

  • IL-12, His, Mouse
    • IL-12, His, Mouse

    IL-12, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Interleukin 12 (IL-12) is a pleiotropic cytokine that plays an essential role in Th1-type immune response against cancer, a condition where cells in a particular part of the body grow and reproduce uncontrollably.
Synonyms CLMF; CLMF2; IL-12A; IL-12B; IL12; IL12 p70; IMD28; IMD29; NFSK; NKSF1; NKSF2; P35; IL-12 subunit p35; IL12A; interleukin 12

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.