IL-1 alpha/IL-1A, His, Mouse
IL-1 Alpha/IL-1A, His, Mouse

The purity of IL-1 alpha/IL-1A, His, Mouse is greater than 95% as determined by SEC-HPLC.

IL-1 Alpha/IL-1A, His, Mouse

IL-1 alpha/IL-1A, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

IL-1 Alpha/IL-1A, His, Mouse

IL-1 alpha/IL-1A, His, Mouse on CM5 Chip can bind Mouse IL-1 alpha, His Tag with an affinity constant of 51.22 nM as determined in SPR assay (Biacore T200).

IL-1 alpha/IL-1A, His, Mouse

The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1α and IL-1β were the first members of the IL-1 family to be described, and both signal via the same receptor, IL-1R. Over the last decade, much progress has been made in our understanding of biogenesis of IL-1β and its functions in human diseases.
Z06181
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Product Introduction
Species Mouse
Protein Construction
IL-1 alpha/IL-1A (Ser115-Ser270)_x000D_
Accession # P01582		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 19.08 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 24-30 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • IL-1 Alpha/IL-1A, His, Mouse
    • IL-1 Alpha/IL-1A, His, Mouse

    The purity of IL-1 alpha/IL-1A, His, Mouse is greater than 95% as determined by SEC-HPLC.

  • IL-1 Alpha/IL-1A, His, Mouse
    • IL-1 Alpha/IL-1A, His, Mouse

    IL-1 alpha/IL-1A, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

  • IL-1 Alpha/IL-1A, His, Mouse
    • IL-1 Alpha/IL-1A, His, Mouse

    IL-1 alpha/IL-1A, His, Mouse on CM5 Chip can bind Mouse IL-1 alpha, His Tag with an affinity constant of 51.22 nM as determined in SPR assay (Biacore T200).


Background
Target Background The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1α and IL-1β were the first members of the IL-1 family to be described, and both signal via the same receptor, IL-1R. Over the last decade, much progress has been made in our understanding of biogenesis of IL-1β and its functions in human diseases.
Synonyms Interleukin-1 alpha; IL-1 alpha; Hematopoietin-1; IL1A; IL1F1; IL-1 ALPHA; IL1α; IL-1A; IL1

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.