Activin RIIB/ACVR2B, His, Mouse
Activin RIIB/ACVR2B, His, Mouse

Immobilized Human Activin A, No Tag at 1 μg /ml (100 μl/well) on the plate. Dose response curve for Activin RIIB/ACVR2B, His, Mouse, His Tag with the EC50 of 10.5ng/ml determined by ELISA.

Activin RIIB/ACVR2B, His, Mouse

The purity of Activin RIIB/ACVR2B, His, Mouse is greater than 95% as determined by SEC-HPLC.

Activin RIIB/ACVR2B, His, Mouse

Activin RIIB/ACVR2B, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Activin RIIB/ACVR2B, His, Mouse

ActRIIB (activin receptor type-2B) is an activin receptor subtype constitutively expressed in the whole body, playing a role in cellular proliferation, differentiation, and metabolism. For its various physiological activities, ActRIIB interacts with activin and multiple other ligands including myostatin (MSTN), growth differentiation factor 11 (GDF11), and bone morphogenetic protein 9 (BMP9).
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Product Introduction
Species Mouse
Protein Construction
Activin RIIB/ACVR2B (Ser19-Thr137)
Accession # P27040-1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 14.78 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 30-50 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • Activin RIIB/ACVR2B, His, Mouse
    • Activin RIIB/ACVR2B, His, Mouse

    Immobilized Human Activin A, No Tag at 1 μg /ml (100 μl/well) on the plate. Dose response curve for Activin RIIB/ACVR2B, His, Mouse, His Tag with the EC50 of 10.5ng/ml determined by ELISA.

  • Activin RIIB/ACVR2B, His, Mouse
    • Activin RIIB/ACVR2B, His, Mouse

    The purity of Activin RIIB/ACVR2B, His, Mouse is greater than 95% as determined by SEC-HPLC.

  • Activin RIIB/ACVR2B, His, Mouse
    • Activin RIIB/ACVR2B, His, Mouse

    Activin RIIB/ACVR2B, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background ActRIIB (activin receptor type-2B) is an activin receptor subtype constitutively expressed in the whole body, playing a role in cellular proliferation, differentiation, and metabolism. For its various physiological activities, ActRIIB interacts with activin and multiple other ligands including myostatin (MSTN), growth differentiation factor 11 (GDF11), and bone morphogenetic protein 9 (BMP9).
Synonyms Activin receptor type-2B; ACVR2B; Activin RIIB

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.