RET, His, Human
RET, His, Human

The purity of RET, His, Human is greater than 95% as determined by SEC-HPLC.

RET, His, Human

RET, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

RET, His, Human

RET is a proto-oncogene encoding a receptor tyrosine kinase. RET regulates key aspects of cellular proliferation, differentiation and survival. The activation of RET via gene fusions or point mutations is closely related to lung, thyroid and other cancers.
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Product Introduction
Species Human
Protein Construction
RET (Leu29-Arg635)_x000D_
Accession # P07949-1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1 EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 68.87 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 90-120 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • RET, His, Human
    • RET, His, Human

    The purity of RET, His, Human is greater than 95% as determined by SEC-HPLC.

  • RET, His, Human
    • RET, His, Human

    RET, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background RET is a proto-oncogene encoding a receptor tyrosine kinase. RET regulates key aspects of cellular proliferation, differentiation and survival. The activation of RET via gene fusions or point mutations is closely related to lung, thyroid and other cancers.
Synonyms Cadherin family member 12; CDHF12; CDHR16; PTC; RET51; HSCR1; MTC1; RET-ELE1; RET51

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.