L1CAM, His, Human
L1CAM, His, Human

Immobilized L1CAM, His, Human, His Tag at 0.2 μg /ml (100 μl/well) on the plate. Dose response curve for Anti-L1CAM Antibody, hFc Tag with the EC50 of 4.6ng/ml determined by ELISA.

L1CAM, His, Human

The purity of L1CAM, His, Human is greater than 95% as determined by SEC-HPLC.

L1CAM, His, Human

L1CAM, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

L1CAM, His, Human

L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described with important functions in the development of the nervous system. Subsequent work discovered that L1CAM is expressed in many human cancers and is often associated with bad prognosis. This is most likely due to the motility and invasion promoting function of L1CAM. L1CAM is a valuable diagnostic/prognostic marker and an attractive target for the therapy of several human cancers.
Z05555
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Product Introduction
Species Human
Protein Construction
L1CAM (Ile20-Glu1120)
Accession # P32004-1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 124.6 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 150-180 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • L1CAM, His, Human
    • L1CAM, His, Human

    Immobilized L1CAM, His, Human, His Tag at 0.2 μg /ml (100 μl/well) on the plate. Dose response curve for Anti-L1CAM Antibody, hFc Tag with the EC50 of 4.6ng/ml determined by ELISA.

  • L1CAM, His, Human
    • L1CAM, His, Human

    The purity of L1CAM, His, Human is greater than 95% as determined by SEC-HPLC.

  • L1CAM, His, Human
    • L1CAM, His, Human

    L1CAM, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described with important functions in the development of the nervous system. Subsequent work discovered that L1CAM is expressed in many human cancers and is often associated with bad prognosis. This is most likely due to the motility and invasion promoting function of L1CAM. L1CAM is a valuable diagnostic/prognostic marker and an attractive target for the therapy of several human cancers.
Synonyms N-CAM-L1; NCAM-L1; CD171; L1CAM; CAML1; MIC5; CALL; CHL1; CHL-1; FLJ44930; L1CAM-2; MGC132578; HSAS; HSAS1; MASA; S10; SPG1

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.