EMMPRIN/CD147, His, Human
EMMPRIN/CD147, His, Human

Immobilized EMMPRIN/CD147, His, Human, His Tag at 1 μg /ml (100 μl/well) on the plate. Dose response curve for Anti-EMMPRIN Antibody, hFc Tag with the EC50 of 3.0ng/ml determined by ELISA.

EMMPRIN/CD147, His, Human

The purity of EMMPRIN/CD147, His, Human is greater than 95% as determined by SEC-HPLC.

EMMPRIN/CD147, His, Human

EMMPRIN/CD147, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

EMMPRIN/CD147, His, Human

CD147, also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulation of extracellular matrix (ECM) remodeling during physiological and pathological processes including wound healing, inflammatory diseases, and cancer. CD147 is a diagnostic and therapeutic target in cancer and inflammatory diseases, either directly or indirectly, by targeting CD147 partners.
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Product Introduction
Species Human
Protein Construction
EMMPRIN/CD147 (Ala22-His205)
Accession # NP_940991.1		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 21.2 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 28-40 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • EMMPRIN/CD147, His, Human
    • EMMPRIN/CD147, His, Human

    Immobilized EMMPRIN/CD147, His, Human, His Tag at 1 μg /ml (100 μl/well) on the plate. Dose response curve for Anti-EMMPRIN Antibody, hFc Tag with the EC50 of 3.0ng/ml determined by ELISA.

  • EMMPRIN/CD147, His, Human
    • EMMPRIN/CD147, His, Human

    The purity of EMMPRIN/CD147, His, Human is greater than 95% as determined by SEC-HPLC.

  • EMMPRIN/CD147, His, Human
    • EMMPRIN/CD147, His, Human

    EMMPRIN/CD147, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background CD147, also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulation of extracellular matrix (ECM) remodeling during physiological and pathological processes including wound healing, inflammatory diseases, and cancer. CD147 is a diagnostic and therapeutic target in cancer and inflammatory diseases, either directly or indirectly, by targeting CD147 partners.
Synonyms Basigin; BSG; CD147; 5F7; M6; OK; TCSF

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.