LAIR2/CD306, His & Avi, Human
LAIR2/CD306, His & Avi, Human

The purity of LAIR2/CD306, His & Avi, Human is greater than 95% as determined by SEC-HPLC.

LAIR2/CD306, His & Avi, Human

LAIR2/CD306, His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

LAIR2/CD306, His & Avi, Human

LAIR2/CD306, His & Avi, Human, His Tag captured on CM5 Chip via Anti-His Antibody can bind Native Human Collagen I protein with an affinity constant of 0.95 nM as determined in SPR assay (Biacore T200).

LAIR2/CD306, His & Avi, Human

The leukocyte-associated immunoglobulin-like receptor 2 (LAIR2) shows increased expression during pregnancy and its reduced expression is associated with pregnancy complications. Although LAIR2 was expressed in the human placenta villus and decidua in the first trimester of pregnancy, it was not expressed in mouse tissues. Knockdown of LAIR2 markedly improved cell viability and inhibited the invasive ability of HTR8/SVneo cells.
Z04974
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Product Introduction
Species Human
Protein Construction
LAIR2/CD306 (Gln22-Pro152)
Accession # Q6ISS4-1		 His Avi
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity LAIR2/CD306, His & Avi, Human captured on CM5 Chip via Anti­His Antibody can bind Native Human Collagen I protein in SPR assay (Biacore T200). Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 17 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 20-25 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • LAIR2/CD306, His & Avi, Human
    • LAIR2/CD306, His & Avi, Human

    The purity of LAIR2/CD306, His & Avi, Human is greater than 95% as determined by SEC-HPLC.

  • LAIR2/CD306, His & Avi, Human
    • LAIR2/CD306, His & Avi, Human

    LAIR2/CD306, His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

  • LAIR2/CD306, His & Avi, Human
    • LAIR2/CD306, His & Avi, Human

    LAIR2/CD306, His & Avi, Human, His Tag captured on CM5 Chip via Anti-His Antibody can bind Native Human Collagen I protein with an affinity constant of 0.95 nM as determined in SPR assay (Biacore T200).


Background
Target Background The leukocyte-associated immunoglobulin-like receptor 2 (LAIR2) shows increased expression during pregnancy and its reduced expression is associated with pregnancy complications. Although LAIR2 was expressed in the human placenta villus and decidua in the first trimester of pregnancy, it was not expressed in mouse tissues. Knockdown of LAIR2 markedly improved cell viability and inhibited the invasive ability of HTR8/SVneo cells.
Synonyms LAIR-2; CD306; LAIR2; MGC71634; XXbac-BCX535A19.6

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.