GITR Ligand/TNFSF18, His, Cynomolgus
GITR Ligand/TNFSF18, His, Cynomolgus

The purity of GITR Ligand/TNFSF18, His, Cynomolgus is greater than 95% as determined by SEC-HPLC.

GITR Ligand/TNFSF18, His, Cynomolgus

GITR Ligand/TNFSF18, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

GITR Ligand/TNFSF18, His, Cynomolgus

GITR Ligand/TNFSF18, His, Cynomolgus, His Tag immobilized on CM5 Chip can bind Cynomolgus GITR, His Tag with an affinity constant of 0.21 μM as determined in SPR assay (Biacore T200).

GITR Ligand/TNFSF18, His, Cynomolgus

B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFF-R.
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Product Introduction
Species Cynomolgus
Protein Construction
GITR Ligand/TNFSF18 (Gln72-Ser199)
Accession # A0A7N9CM47		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 15.62 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 17-27 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • GITR Ligand/TNFSF18, His, Cynomolgus
    • GITR Ligand/TNFSF18, His, Cynomolgus

    The purity of GITR Ligand/TNFSF18, His, Cynomolgus is greater than 95% as determined by SEC-HPLC.

  • GITR Ligand/TNFSF18, His, Cynomolgus
    • GITR Ligand/TNFSF18, His, Cynomolgus

    GITR Ligand/TNFSF18, His, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

  • GITR Ligand/TNFSF18, His, Cynomolgus
    • GITR Ligand/TNFSF18, His, Cynomolgus

    GITR Ligand/TNFSF18, His, Cynomolgus, His Tag immobilized on CM5 Chip can bind Cynomolgus GITR, His Tag with an affinity constant of 0.21 μM as determined in SPR assay (Biacore T200).


Background
Target Background B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFF-R.
Synonyms TNFSF18; AITRL; TL6; GITRL; GITR Ligand

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.