B7-1/CD80 hFc Chimera, Cynomolgus
B7-1/CD80 HFc Chimera, Cynomolgus

Immobilized Cynomolgus CTLA-4, His Tag at 0.5 μg/ml (100 μI/well) on the plate. Dose response curve for B7-1/CD80 hFc Chimera, Cynomolgus, hFc Tag with the EC50 of 15.4ng/ml determined by ELISA.

B7-1/CD80 HFc Chimera, Cynomolgus

The purity of B7-1/CD80 hFc Chimera, Cynomolgus is greater than 95% as determined by SEC-HPLC.

B7-1/CD80 HFc Chimera, Cynomolgus

B7-1/CD80 hFc Chimera, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

B7-1/CD80 hFc Chimera, Cynomolgus

Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4.
Z04738
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Product Introduction
Species Cynomolgus
Protein Construction
B7-1/CD80 (Val35-Asn242)
Accession # G7NXN7		 hFc
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 49.84 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 60-80 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • B7-1/CD80 HFc Chimera, Cynomolgus
    • B7-1/CD80 HFc Chimera, Cynomolgus

    Immobilized Cynomolgus CTLA-4, His Tag at 0.5 μg/ml (100 μI/well) on the plate. Dose response curve for B7-1/CD80 hFc Chimera, Cynomolgus, hFc Tag with the EC50 of 15.4ng/ml determined by ELISA.

  • B7-1/CD80 HFc Chimera, Cynomolgus
    • B7-1/CD80 HFc Chimera, Cynomolgus

    The purity of B7-1/CD80 hFc Chimera, Cynomolgus is greater than 95% as determined by SEC-HPLC.

  • B7-1/CD80 HFc Chimera, Cynomolgus
    • B7-1/CD80 HFc Chimera, Cynomolgus

    B7-1/CD80 hFc Chimera, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.


Background
Target Background Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4.
Synonyms CD80 molecule; B7; B71; B7-1; BB1; CD28LG1; CD80; B7.1; CD28LG1; LAB7

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.