Immobilized PDGF R beta/CD140b[Biotin], His & Avi, Human, His Avi Tag at 1 μg/ml(100 μl/well) on the streptavidin precoated plate(5 μg/ml). Dose response curve for Anti-PDGFRB Antibody, hFc Tag with the EC50 of 8.8ng/ml determined by ELISA.
The purity of PDGF R beta/CD140b[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC.
PDGF R beta/CD140b[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
PDGF R beta/CD140b[Biotin], His & Avi, Human
PDGF is a major serum mitogen that can exist as a homo or hetero-dimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA,PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities. Where as PDGF R alpha binds all three PDGF isoforms with high affinity, PDGF R beta binds PDGF-BB only with high-affinity. PDGF R plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites.
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| ¥123,118.00 | |
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