The purity of VEGF R2/KDR[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC.

VEGF R2/KDR[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Immobilized VEGF R2/KDR[Biotin], His & Avi, Human at 0.5 μg/ml (100 μl/Well) on streptavidin(5 μg/ml) precoated plate. Dose response curve for Anti-VEGF R2 Antibody, hFc Tag with the EC50 of 2.6 ng/ml determined by ELISA.

Serial dilutions of Anti-VEGF165 Antibody were added into Human VEGF165, No Tag : VEGF R2/KDR[Biotin], His&Avi, Human, His Avi Tag binding reactioins. The half maximal inhibitiory concentration(IC50) is 0.30 mg/ml.

Immobilized Human VEGF165, No Tag at 5 mg/ml (100 mI/well) on the plate. Dose response curve for VEGF R2/KDR[Biotin], His&Avi, Human, His-Avi Tag with the EC50 of 1.27 mg/ml determined by ELISA.

VEGF R2/KDR[Biotin], His&Avi, Human

Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. The tyrosine kinase receptor vascular endothelial growth factor receptor 2 (VEGFR2) is a key regulator of angiogenesis.

Cat. No.	Z03970
Size	100 μg : Quote 500 μg : Quote Buy in bulk
Quantity
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Price	¥121,253.00


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Product Introduction

Species

Human

Protein Construction

VEGF R2/KDR (Ala20-Glu764) Accession # P35968-1	His	Avi
N-term		C-term

Conjugate

Biotin

Purity

> 95% as determined by Bis-Tris PAGE

Endotoxin Level

Less than 1EU per μg by the LAL method.

Biological Activity

Measured by its binding ability in a functional ELISA.Test result was comparable to standard batch.

Expression System

HEK293

Theoretical Molecular Weight

86.2 kDa

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 120-160 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from a 0.22 μm filtered solution in PBS, (pH 7.4).

Reconstitution

It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O more than 100 μg/ml.

Storage & Stability

Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples

The purity of VEGF R2/KDR[Biotin], His & Avi, Human is greater than 95% as determined by SEC-HPLC.

VEGF R2/KDR[Biotin], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Immobilized Human VEGF165, No Tag at 5 mg/ml (100 mI/well) on the plate. Dose response curve for VEGF R2/KDR[Biotin], His&Avi, Human, His-Avi Tag with the EC50 of 1.27 mg/ml determined by ELISA.

Background

Target Background	Vascular endothelial growth factor receptor 2 (VEGFR2) is one kind of tyrosine kinase receptors. VEGFR2 acts as a cell-surface receptor for VEGFA, VEGFB and PGF. It plays an important role in the development of embryonic vasculature, cell survival and cancer cell invasion. VEGFR2 is a key regulator of angiogenesis.
Synonyms	CD309; KDR; VEGFR; VEGFR2; VEGFR-21; FLK1; KRD1; Ly73

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.

VEGF R2/KDR[Biotin], His&Avi, Human

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