VEGF R3/FLT4, His&Avi, Human
VEGF R3/FLT4, His&Avi, Human

The purity of VEGF R3/FLT4, His & Avi, Human is greater than 95% as determined by SEC-HPLC.

VEGF R3/FLT4, His&Avi, Human

VEGF R3/FLT4, His & Avi, Humanon Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

VEGF R3/FLT4, His&Avi, Human

VEGF R3/FLT4, His&Avi, Human, His Tag immobilized on CM5 Chip can bind Human VEGF-C, His Tag with an affinity constant of 0.29 nM as determined in SPR assay (Biacore T200).

VEGF R3/FLT4, His&Avi, Human

Vascular endothelial growth factor (VEGF) and its receptors VEGF-R1, -R2 and -R3 play important roles in tumor angiogenesis and are associated with poor prognosis in several solid tumors.VEGF-R1, -R2 and -R3 were highly expressed in CRC cells and stromal vessels. VEGF-R1 strong positive staining correlated with shorter survival after CRC surgery.
Z03967
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Product Introduction
Species Human
Protein Construction
VEGF R3/FLT4 (Tyr25-Ile776)
Accession # P35916-1		 His Avi
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 87.4 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 110-130 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4.
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O more than 100 μg/ml.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.

Examples
  • VEGF R3/FLT4, His&Avi, Human
    • VEGF R3/FLT4, His&Avi, Human

    The purity of VEGF R3/FLT4, His & Avi, Human is greater than 95% as determined by SEC-HPLC.

  • VEGF R3/FLT4, His&Avi, Human
    • VEGF R3/FLT4, His&Avi, Human

    VEGF R3/FLT4, His & Avi, Humanon Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

  • VEGF R3/FLT4, His&Avi, Human
    • VEGF R3/FLT4, His&Avi, Human

    VEGF R3/FLT4, His&Avi, Human, His Tag immobilized on CM5 Chip can bind Human VEGF-C, His Tag with an affinity constant of 0.29 nM as determined in SPR assay (Biacore T200).


Background
Target Background Vascular endothelial growth factor receptor 3 (VEGFR3) is one kind of tyrosine-protein kinase. VEGFR3 acts as a cell-surface receptor for VEGFC and VEGFD. It is a key regulator of lymphatic system development and establishment. VEGFR3 plays important roles in angiogenesis. It is also up-regulated in the endothelium of blood vessels in breast cancer and various other tumors.
Synonyms VEGFR-3; FLT-4; LMPH1A; PCLFLT41; VEGFR3; FLT-41; PCL

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.