Immobilized MSLN/Mesothelin(306-590) hFc Chimera, Cynomolgus, hFc Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-MSLN Antibody, hFc Tag with the EC50 of 37.6 ng/ml determined by ELISA.
The purity of MSLN/Mesothelin(306-590) hFc Chimera, Cynomolgus is greater than 95% as determined by SEC-HPLC.
MSLN/Mesothelin(306-590) hFc Chimera, Cynomolgus on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
MSLN/Mesothelin(306-590) hFc Chimera, Cynomolgus
Mesothelin, also known as MSLN, is a protein that in humans is encoded by the MSLN gene.Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF). Although it has been proposed that mesothelin may be involved in cell adhesion, its biological function is not known.A knockout mouse line that lacks mesothelin reproduces and develops normally.
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