Tau peptide (45-73) (Exon2/Insert1 domain)

Tau peptide (45-73) (Exon2/Insert1 domain)

Tau Peptide (45-73) is a 29-amino acid long peptide derived from the Exon 2/Insert 1 domain.
RP30888
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Description

TAU proteins belong to the microtubule-associated protein (MAP) family and are involved in the pathogenesis of Alzheimer’s disease. In the human brain, there are six TAU isoforms ranging from 352 to 441 amino acids in length. These isoforms vary at the carboxyl terminal according to the presence of either three repeat or four repeat domains (R1-R4), in addition to the presence or absence of one or two insert domains at the amino-terminus. Tau Peptide (45-73) is a 29-amino acid long peptide derived from the Exon 2/Insert 1 domain.

Overview
Synonyms Tau peptide (45-73) (Exon2/Insert1 domain)
Description TAU proteins belong to the microtubule-associated protein (MAP) family and are involved in the pathogenesis of Alzheimer’s disease. In the human brain, there are six TAU isoforms ranging from 352 to 441 amino acids in length. These isoforms vary at the carboxyl terminal according to the presence of either three repeat or four repeat domains (R1-R4), in addition to the presence or absence of one or two insert domains at the amino-terminus. Tau Peptide (45-73) is a 29-amino acid long peptide derived from the Exon 2/Insert 1 domain.
Sequence
{Glu}{Ser}{Pro}{Leu}{Gln}{Thr}{Pro}{Thr}{Glu}{Asp}{Gly}{Ser}
{Glu}{Glu}{Pro}{Gly}{Ser}{Glu}{Thr}{Ser}{Asp}{Ala}{Lys}{Ser}
{Thr}{Pro}{Thr}{Ala}{Glu}
Sequence Shortening ESPLQTPTEDGSEEPGSETSDAKSTPTAE
Molecular Formula C₁₂₀H₁₈₉N₃₁O₅₇
Molecular Weight 2977.99

Properties
Length 29
Purity >95%
Solubility Can be dissolved in Ultrapure water
Form Lyophilized
Storage Store at -20°C. Keep tightly closed. Store in a cool dry place.