Catalog Peptides » GS-PepFirming™ Acetyl Hexapeptide-8

GS-PepFirming™ Acetyl Hexapeptide-8

Acetyl hexapeptide-8, also known as acetyl hexapeptide-3 or Argireline, is a neurotransmitter inhibitor as oligopeptide consisting of six amino acid residues. It is widely used in anti-wrinkle products with higher activity and lower side effects as a biosafe alternative to BoNTs.
RP30143
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Overview
Description Acetyl hexapeptide-8, also known as acetyl hexapeptide-3 or Argireline, is a neurotransmitter inhibitor as oligopeptide consisting of six amino acid residues. It is widely used in anti-wrinkle products with higher activity and lower side effects as a biosafe alternative to BoNTs.
Cas No 616204-22-9
Molecular Formula C34H60N14O12S
Molecular Weight 889.0

Properties
Purity >95%
Form Lyophilized
Storage Store at -20°C. Keep tightly closed. Store in a cool dry place.
Note Processing and Dosage: The peptide can be incorporated at a temperature below 40℃ during the final stage of cosmetic manufacturing. It is recommended that 5 to 5000 ppm of the powder is present in the final formulation in order to obtain significant activity.

Applications
Acetyl hexapeptide-8 is a mimic of the N-terminal end of SNAP-25 which competes with SNAP-25 for a position in the SNARE complex, thereby modulating its formation. If the SNARE complex is slightly destabilized, the vesicle cannot release neurotransmitters efficiently and therefore muscle contraction is attenuated, preventing the formation of lines and wrinkles. It can be incorporated in cosmetic formulations such as emulsions, gels, essence, eye cream, etc., where removal of the deep lines or wrinkles in the forehead or around the eyes area is desired.