安定細胞株製品 » Human Recombinant Neuropeptide S Receptor Isoform A Stable Cell Line
CHO-K1/NPS1a/Gα15 Stable Cell Line

CHO-K1/NPS1a/Gα15 Stable Cell Line

The neuropeptide S receptor isoform a (NPS1a) is Gq/11 and Gs-coupled GPCRs expressed in the bronchial smooth muscle cells, basally in colon epithelium and in occasional basal keratinocytes in skin. An Asn107->Ile mutation is significantly up-regulated in a mouse model of ovalbumen-induced lung inflammation supporting a role in the pathogenesis of asthma.
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Description

The neuropeptide S receptor isoform a (NPS1a) is Gq/11 and Gs-coupled GPCRs expressed in the bronchial smooth muscle cells, basally in colon epithelium and in occasional basal keratinocytes in skin. An Asn107->Ile mutation is significantly up-regulated in a mouse model of ovalbumen-induced lung inflammation supporting a role in the pathogenesis of asthma.
Synonyms

Neuropeptide S receptor(Isoform A or isoform1), GPR154, GPRA, PGR14

Overview
Applications Functional assay for NPS1a receptor

Product Introduction
Species Human

Culture Conditions
Freeze Medium 45% culture medium, 45% FBS (Cat. #10099-141, Gibco), 10% DMSO (Cat. #D2650, Sigma)
Culture Medium Ham’s F-12K (Kaighn’s) (Cat. #21127-022, Gibco), 10% FBS, 200 μg/ml Zeocin (Cat. #R250-01, Life Technologies) and 100 μg/ml Hygromycin B (Cat. #10687010, Invitrogen)

Examples
  • CHO-K1/NPS1a/Gα15 Stable Cell Line
    • CHO-K1/NPS1a/Gα15 Stable Cell Line