il-6 cDNA ORF clone, Takifugu rubripes(torafugu)

Gene
Clones
gRNAs

Summary

Gene Symbol	il-6
Entrez Gene ID	503562
Full Name	interleukin-6
Synonyms	il6
Gene Type	protein-coding
Organism	Takifugu rubripes(torafugu)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001032722.1	NP_001027894.1	interleukin-6 precursor

Pathways from BioSystems
Gene Ontology
Bibliography

Related articles in PubMed

Teleost IL-6 promotes antibody production through STAT3 signaling via IL-6R and gp130.
Kaneda M, Odaka T, Suetake H, Tahara D, Miyadai T
Developmental and comparative immunology38(2)224-31(2012 Oct)

Characterisation and expression analysis of an interleukin 6 homologue in the Japanese pufferfish, Fugu rubripes.
Bird S, Zou J, Savan R, Kono T, Sakai M, Woo J, Secombes C
Developmental and comparative immunology29(9)775-89(2005)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results suggest that fugu IL-6 regulates antibody production through STAT3 signaling via IL-6R and gp130.
Title: Teleost IL-6 promotes antibody production through STAT3 signaling via IL-6R and gp130.

The following il-6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the il-6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OTo00013	NM_001032722.1 Latest version!	Takifugu rubripes interleukin-6 (il-6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

il-6 ( NM_001032722.1 ) cDNA ORF clone, Takifugu rubripes(torafugu) -> NP_001027894.1 Takifugu rubripes interleukin-6 (il-6), mRNA.

Price & Availability↑

CloneID	OTo00013
Clone ID Related Accession (Same CDS sequence)	NM_001032722.1
Accession Version	NM_001032722.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 684bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Takifugu rubripes(torafugu)
Product	interleukin-6 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ544721.2. ##Evidence-Data-START## Transcript exon combination :: AJ544721.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02369524, SAMN07172356 [ECO:0000348] ##Evidence-Data-END##

ATGGCTTCCA TCAGTTACCT GCTCGCTCCT CTGGTGCTGG CTGCGGTGCT GCAGCCCACC 
GCAGGGGCCC CGCTTGACGC GCCCACCGAG AGCCCCGCAG GGGAGACCTC AGGGGAGGAG 
GCGGAGACCG GGAGCCCCGA TGACGCGCTG GCGGTGGCCC TTGAATCTGT TCTCGGGGCC 
ACCAAACTGC ATAAAAACGA GTTCTTAGTT GAATTTCAAG GGGAGGTAAA GTACGACTTT 
CTGGACCGTT ACAAAATCCC ATCTCTTCCA GCCAAGTGCC CTTACTCCAA CTTTGGCAAG 
GATGCTTGTC TACGAAGGTT ACTCGAAGGT CTCCTTATCT ACTCAGTTCT TCTCAAGCGG 
GTTGAAGAGG AATTTCCTTC CAGCAGTATC CTCTCAGAGG TCAGATTCTA CAGCAACATC 
CTGATCAAAG AGCTGGAAAA CAAGGTGAGG GACCGTGACC AGGTGATGAG GCTGACCAGC 
AGCCAGGAGG AGCAGCTGCT TAAGGACACC GACTACCCCG ACACCTTCCA CAGGAAGATG 
ACCGCGCACG GCATCCTGTA CAACCTCCAC TACTTCCTGG TCGACTGCAG GAGGGTGATC 
AACAAGAGAG CGAAGCACAG GGAGTCCGCA GGCAGCAGGG TCGTGAGGGC CGTCACCTTC 
TACCACCCAA AGAAGAGATC GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001027894.1
CDS	183..866
Translation	MASISYLLAPLVLAAVLQPTAGAPLDAPTESPAGETSGEEAETGSPDDALAVALESVLGATKLHKNEFLVEFQGEVKYDFLDRYKIPSLPAKCPYSNFGKDACLRRLLEGLLIYSVLLKRVEEEFPSSSILSEVRFYSNILIKELENKVRDRDQVMRLTSSQEEQLLKDTDYPDTFHRKMTAHGILYNLHYFLVDCRRVINKRAKHRESAGSRVVRAVTFYHPKKRS

Target ORF information:

RefSeq Version	NM_001032722.1
Organism	Takifugu rubripes(torafugu)
Definition	Takifugu rubripes interleukin-6 (il-6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001032722.1

ORF Insert Sequence:

ATGGCTTCCA TCAGTTACCT GCTCGCTCCT CTGGTGCTGG CTGCGGTGCT GCAGCCCACC 
GCAGGGGCCC CGCTTGACGC GCCCACCGAG AGCCCCGCAG GGGAGACCTC AGGGGAGGAG 
GCGGAGACCG GGAGCCCCGA TGACGCGCTG GCGGTGGCCC TTGAATCTGT TCTCGGGGCC 
ACCAAACTGC ATAAAAACGA GTTCTTAGTT GAATTTCAAG GGGAGGTAAA GTACGACTTT 
CTGGACCGTT ACAAAATCCC ATCTCTTCCA GCCAAGTGCC CTTACTCCAA CTTTGGCAAG 
GATGCTTGTC TACGAAGGTT ACTCGAAGGT CTCCTTATCT ACTCAGTTCT TCTCAAGCGG 
GTTGAAGAGG AATTTCCTTC CAGCAGTATC CTCTCAGAGG TCAGATTCTA CAGCAACATC 
CTGATCAAAG AGCTGGAAAA CAAGGTGAGG GACCGTGACC AGGTGATGAG GCTGACCAGC 
AGCCAGGAGG AGCAGCTGCT TAAGGACACC GACTACCCCG ACACCTTCCA CAGGAAGATG 
ACCGCGCACG GCATCCTGTA CAACCTCCAC TACTTCCTGG TCGACTGCAG GAGGGTGATC 
AACAAGAGAG CGAAGCACAG GGAGTCCGCA GGCAGCAGGG TCGTGAGGGC CGTCACCTTC 
TACCACCCAA AGAAGAGATC GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Teleost IL-6 promotes antibody production through STAT3 signaling via IL-6R and gp130.
Developmental and comparative immunology38(2)224-31(2012 Oct)
Kaneda M,Odaka T,Suetake H,Tahara D,Miyadai T

Characterisation and expression analysis of an interleukin 6 homologue in the Japanese pufferfish, Fugu rubripes.
Developmental and comparative immunology29(9)775-89(2005)
Bird S,Zou J,Savan R,Kono T,Sakai M,Woo J,Secombes C